ARTICLES:

GM Pieper, GA Clarke, and GJ Gross

Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes
J Pharmacol Exp Ther 1994 269: 451-456. [Abstract] [PDF]  

M Ozawa, K Sugimachi, Y Nakada-Kometani, T Akai, and M Yamaguchi

Chronic pharmacological activities of the novel anxiolytic beta- carboline abecarnil in rats
J Pharmacol Exp Ther 1994 269: 457-462. [Abstract] [PDF]  

YX Wang and CC Pang

Effects of adrenalectomy and chemical sympathectomy on pressor and tachycardic responses to diphenyleneiodonium
J Pharmacol Exp Ther 1994 269: 463-469. [Abstract] [PDF]  

E Agneter, IS Hoffmann, EA Singer, and LX Cubeddu

Behavior of mesocortical dopamine terminals during single and repetitive stimulation: comparison with nigrostriatal neurons
J Pharmacol Exp Ther 1994 269: 470-476. [Abstract] [PDF]  

R Sheldon, E Thakore, L Wilson, and H Duff

Interaction of drug metabolites with the class I antiarrhythmic drug receptor on rat cardiac myocytes
J Pharmacol Exp Ther 1994 269: 477-481. [Abstract] [PDF]  

S Hashimoto, Y Kawai, and T Ohhashi

Effects of vasoactive substances on the pig isolated hepatic lymph vessels
J Pharmacol Exp Ther 1994 269: 482-488. [Abstract] [PDF]  

H Ohnota, T Koizumi, N Tsutsumi, M Kobayashi, S Inoue, and F Sato

Novel rapid- and short-acting hypoglycemic agent, a calcium(2s)-2- benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) that acts on the sulfonylurea receptor: comparison of effects between KAD-1229 and gliclazide
J Pharmacol Exp Ther 1994 269: 489-495. [Abstract] [PDF]  

NM Griffiths, BH Hirst, and NL Simmons

Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?
J Pharmacol Exp Ther 1994 269: 496-502. [Abstract] [PDF]  

LG Aguayo and J Grossie

Dopamine inhibits a sustained calcium current through activation of alpha adrenergic receptors and a GTP-binding protein in adult rat sympathetic neurons
J Pharmacol Exp Ther 1994 269: 503-508. [Abstract] [PDF]  

JS Zhang, JC Van Meel, M Pfaffendorf, and PA Van Zwieten

Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve
J Pharmacol Exp Ther 1994 269: 509-514. [Abstract] [PDF]  

C Breugnot, S Privat, C Guillonneau, G Regnier, F Bouzom, JP Vilaine, and A Lenaers

S 12340: a potent inhibitor of the oxidative modification of low- density lipoprotein in vitro and ex vivo in WHHL rabbits
J Pharmacol Exp Ther 1994 269: 515-520. [Abstract] [PDF]  

A Hoogerkamp, PW Vis, M Danhof, and RA Voskuyl

Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat
J Pharmacol Exp Ther 1994 269: 521-528. [Abstract] [PDF]  

Y Egi, Y Matsumura, S Murata, T Umekawa, K Hisaki, M Takaoka, and S Morimoto

The effects of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs
J Pharmacol Exp Ther 1994 269: 529-535. [Abstract] [PDF]  

GJ Grover, AJ D'Alonzo, PG Sleph, S Dzwonczyk, TA Hess, and RB Darbenzio

The cardioprotective and electrophysiological effects of cromakalim are attenuated by meclofenamate through a cyclooxygenase-independent mechanism
J Pharmacol Exp Ther 1994 269: 536-540. [Abstract] [PDF]  

JJ Jr Lynch, AA Wallace, RF 3rd Stupienski, EP Baskin, CM Beare, SD Appleby, JJ Salata, NK Jurkiewicz, MC Sanguinetti, and RB Stein

Cardiac electrophysiologic and antiarrhythmic actions of two long- acting spirobenzopyran piperidine class III agents, L-702,958 and L- 706,000 [MK-499]
J Pharmacol Exp Ther 1994 269: 541-554. [Abstract] [PDF]  

CS Konkoy, SM Waters, and TP Davis

Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices
J Pharmacol Exp Ther 1994 269: 555-563. [Abstract] [PDF]  

F Menzaghi, RL Howard, SC Heinrichs, W Vale, J Rivier, and GF Koob

Characterization of a novel and potent corticotropin-releasing factor antagonist in rats
J Pharmacol Exp Ther 1994 269: 564-572. [Abstract] [PDF]  

AJ Carter

Many agents that antagonize the NMDA receptor-channel complex in vivo also cause disturbances of motor coordination
J Pharmacol Exp Ther 1994 269: 573-580. [Abstract] [PDF]  

BI Ghanayem, IM Sanchez, and LT Burka

Investigation of methacrylonitrile metabolism and the metabolic basis for the differences in its toxicity in rats and mice
J Pharmacol Exp Ther 1994 269: 581-588. [Abstract] [PDF]  

M Ito, A Naruse, I Yamamoto, M Oguri, Y Suzuki, N Satake, and S Shibata

Nephrosis augments contractile response to adrenoceptor agonists by the decrease in release of endothelium-derived relaxing factor from the endothelial cells
J Pharmacol Exp Ther 1994 269: 589-595. [Abstract] [PDF]  

BL Hodges, MJ Gagnon, TR Gillespie, JR Breneisen, DF O'Leary, S Hara, and RM Quock

Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade
J Pharmacol Exp Ther 1994 269: 596-600. [Abstract] [PDF]  

CE McDonald, MJ Gagnon, EA Ellenberger, BL Hodges, JK Ream, SA Tousman, and RM Quock

Inhibitors of nitric oxide synthesis antagonize nitrous oxide antinociception in mice and rats
J Pharmacol Exp Ther 1994 269: 601-608. [Abstract] [PDF]  

TC Krejcie, TK Henthorn, CA Shanks, and MJ Avram

A recirculatory pharmacokinetic model describing the circulatory mixing, tissue distribution and elimination of antipyrine in dogs
J Pharmacol Exp Ther 1994 269: 609-616. [Abstract] [PDF]  

SW Watts and RC Webb

Mechanism of ergonovine-induced contraction in the mesenteric artery from deoxycorticosterone acetate-salt hypertensive rat
J Pharmacol Exp Ther 1994 269: 617-625. [Abstract] [PDF]  

RK Rao, PJ Riviere, X Pascaud, JL Junien, and F Porreca

Tonic regulation of mouse ileal ion transport by nitric oxide
J Pharmacol Exp Ther 1994 269: 626-631. [Abstract] [PDF]  

SM Sadrzadeh, AA Nanji, and PL Price

The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats
J Pharmacol Exp Ther 1994 269: 632-636. [Abstract] [PDF]  

TM Cabrera and G Battaglia

Delayed decreases in brain 5-hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine
J Pharmacol Exp Ther 1994 269: 637-645. [Abstract] [PDF]  

M Tence, J Cordier, J Premont, and J Glowinski

Muscarinic cholinergic agonists stimulate arachidonic acid release from mouse striatal neurons in primary culture
J Pharmacol Exp Ther 1994 269: 646-653. [Abstract] [PDF]  

P Wils, A Warnery, V Phung-Ba, S Legrain, and D Scherman

High lipophilicity decreases drug transport across intestinal epithelial cells
J Pharmacol Exp Ther 1994 269: 654-658. [Abstract] [PDF]  

H Hohage, M Lohr, U Querl, and J Greven

The renal basolateral transport system for organic anions: properties of the regulation mechanism
J Pharmacol Exp Ther 1994 269: 659-664. [Abstract] [PDF]  

T Maurice, M Hiramatsu, T Kameyama, T Hasegawa, and T Nabeshima

Cholecystokinin-related peptides, after systemic or central administration, prevent carbon monoxide-induced amnesia in mice
J Pharmacol Exp Ther 1994 269: 665-673. [Abstract] [PDF]  

CA Branch and MM Knuepfer

Causes of differential cardiovascular sensitivity to cocaine. I: Studies in conscious rats
J Pharmacol Exp Ther 1994 269: 674-683. [Abstract] [PDF]  

KJ Ullrich, G Fritzsch, G Rumrich, and C David

Polysubstrates: substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: sulfamoyl-, sulfonylurea-, thiazide- and benzeneamino-carboxylate (nicotinate) compounds
J Pharmacol Exp Ther 1994 269: 684-692. [Abstract] [PDF]  

DJ Carr, LR Gerak, and CP France

Naltrexone antagonizes the analgesic and immunosuppressive effects of morphine in mice
J Pharmacol Exp Ther 1994 269: 693-698. [Abstract] [PDF]  

ET Iwamoto and L Marion

Pharmacological evidence that nitric oxide mediates the antinociception produced by muscarinic agonists in the rostral ventral medulla of rats
J Pharmacol Exp Ther 1994 269: 699-708. [Abstract] [PDF]  

QM Chen, DD Smyth, JK McKenzie, GB Glavin, JG Gu, JD Geiger, and FS LaBella

Chlorotyrosine exerts renal effects and antagonizes renal and gastric responses to atrial natriuretic peptide
J Pharmacol Exp Ther 1994 269: 709-716. [Abstract] [PDF]  

JT Emmick, S Kwon, KR Bidasee, KT Besch, and HR Jr Besch

Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes
J Pharmacol Exp Ther 1994 269: 717-724. [Abstract] [PDF]  

A Nishida, K Miyata, R Tsutsumi, H Yuki, S Akuzawa, A Kobayashi, T Kamato, H Ito, M Yamano, and Y Katuyama

Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2- oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo
J Pharmacol Exp Ther 1994 269: 725-731. [Abstract] [PDF]  

HT Yang and M Endoh

Dissociation of the positive inotropic effect of methoxamine from the hydrolysis of phosphoinositide in rabbit ventricular myocardium: a comparison with the effects of phenylephrine and the subtype of the alpha-1 adrenoceptor involved
J Pharmacol Exp Ther 1994 269: 732-742. [Abstract] [PDF]  

GR King, EH Jr Ellinwood, C Silvia, CM Joyner, Z Xue, MG Caron, and TH Lee

Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function
J Pharmacol Exp Ther 1994 269: 743-749. [Abstract] [PDF]  

CL Williams, GC Rosenfeld, N Dafny, SN Fang, VJ Hruby, G Bowden, CA Cullinan, and TF Burks

SNF9007: a novel analgesic that acts simultaneously at delta 1, delta 2 and mu opioid receptors
J Pharmacol Exp Ther 1994 269: 750-755. [Abstract] [PDF]  

LO Derewlany, B Knie, and G Koren

Arylamine N-acetyltransferase activity of the human placenta
J Pharmacol Exp Ther 1994 269: 756-760. [Abstract] [PDF]  

LO Derewlany, B Knie, and G Koren

Human placental transfer and metabolism of p-aminobenzoic acid
J Pharmacol Exp Ther 1994 269: 761-765. [Abstract] [PDF]  

G Alloatti, G Montrucchio, and G Camussi

Role of platelet-activating factor (PAF) in oxygen radical-induced cardiac dysfunction
J Pharmacol Exp Ther 1994 269: 766-771. [Abstract] [PDF]  

P Savi, MC Laplace, JP Maffrand, and JM Herbert

Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine
J Pharmacol Exp Ther 1994 269: 772-777. [Abstract] [PDF]  

RH Schwinger, M Bohm, A Koch, I Morano, JC Ruegg, and E Erdmann

Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium
J Pharmacol Exp Ther 1994 269: 778-786. [Abstract] [PDF]  

C Perret, MT Foultier, V Vonarx-Coinsman, O Quancard, A Combre, and T Patrice

Malondialdehyde dosimetry in laser-irradiated tissues sensitized by hematoporphyrin derivative
J Pharmacol Exp Ther 1994 269: 787-791. [Abstract] [PDF]  

U McCann, G Hatzidimitriou, A Ridenour, C Fischer, J Yuan, J Katz, and G Ricaurte

Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated
J Pharmacol Exp Ther 1994 269: 792-798. [Abstract] [PDF]  

H Hara, K Tanaka, Y Harada, and T Sukamoto

Sigma receptor-mediated effects of a new antiulcer agent, KB-5492, on experimental gastric mucosal lesions and gastric alkaline secretion in rats
J Pharmacol Exp Ther 1994 269: 799-805. [Abstract] [PDF]  

KM Merchant, GR Hanson, and DM Dorsa

Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: comparison with acute haloperidol effects
J Pharmacol Exp Ther 1994 269: 806-812. [Abstract] [PDF]  

JH Hochman, JA Fix, and EL LeCluyse

In vitro and in vivo analysis of the mechanism of absorption enhancement by palmitoylcarnitine
J Pharmacol Exp Ther 1994 269: 813-822. [Abstract] [PDF]  

M Ohtsuyama, F Sato, T Toyomoto, and K Sato

Stimulation of Cl conductance by minoxidil sulfate and K conductance by minoxidil in eccrine clear cells
J Pharmacol Exp Ther 1994 269: 823-831. [Abstract] [PDF]  

AA Nanji, S Zhao, S Khwaja, SM Sadrzadeh, and DJ Waxman

Cimetidine prevents alcoholic hepatic injury in the intragastric feeding rat model
J Pharmacol Exp Ther 1994 269: 832-837. [Abstract] [PDF]  

CA Louis, SG Wood, V Kostrubsky, PR Sinclair, and JF Sinclair

Synergistic increases in rat hepatic cytochrome P450s by ethanol and isopentanol
J Pharmacol Exp Ther 1994 269: 838-845. [Abstract] [PDF]  

D Van Rossum, DP Menard, A Fournier, S St-Pierre, and R Quirion

Binding profile of a selective calcitonin gene-related peptide (CGRP) receptor antagonist ligand, [125I-Tyr]hCGRP8-37, in rat brain and peripheral tissues
J Pharmacol Exp Ther 1994 269: 846-853. [Abstract] [PDF]  

SH Graham, J Chen, J Lan, MJ Leach, and RP Simon

Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion
J Pharmacol Exp Ther 1994 269: 854-859. [Abstract] [PDF]  

T Umekawa, Y Matsumura, N Yoshimura, S Murata, K Takada, Y Tsukahara, M Takaoka, and S Morimoto

Platelets-induced stimulation of endothelin-1 production and inhibition by phosphoramidon
J Pharmacol Exp Ther 1994 269: 860-866. [Abstract] [PDF]  

CG Plopper, AJ Weir, SJ Nishio, A Chang, M Voit, RM Philpot, and AR Buckpitt

Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits
J Pharmacol Exp Ther 1994 269: 867-880. [Abstract] [PDF]  

M Cho, C Chichester, D Morin, C Plopper, and A Buckpitt

Covalent interactions of reactive naphthalene metabolites with proteins
J Pharmacol Exp Ther 1994 269: 881-889. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1994 269: 889. [Abstract] [PDF]  

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