ARTICLES:

J Imagawa, K Kamei, S Yoshida, I Sugo, T Koga, and H Nabata

In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig
J Pharmacol Exp Ther 1994 269: 1-6. [Abstract] [PDF]  

F Betoin, D Ardid, A Herbet, O Aumaitre, JL Kemeny, P Duchene-Marullaz, J Lavarenne, and A Eschalier

Evidence for a central long-lasting antinociceptive effect of vapreotide, an analog of somatostatin, involving an opioidergic mechanism
J Pharmacol Exp Ther 1994 269: 7-14. [Abstract] [PDF]  

J Itoh, M Ukai, and T Kameyama

Dynorphin A-(1-13) potently improves the impairment of spontaneous alternation performance induced by the mu-selective opioid receptor agonist DAMGO in mice
J Pharmacol Exp Ther 1994 269: 15-21. [Abstract] [PDF]  

T Colombo, M Zucchetti, and M D'Incalci

Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats
J Pharmacol Exp Ther 1994 269: 22-27. [Abstract] [PDF]  

MM Barzago, D Omarini, A Bortolotti, FF Stellari, G Lucchini, S Efrati, and M Bonati

Mefloquine transfer during in vitro human placenta perfusion
J Pharmacol Exp Ther 1994 269: 28-31. [Abstract] [PDF]  

M Serra, CA Ghiani, C Motzo, T Cuccheddu, S Floris, P Giusti, and G Biggio

Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function
J Pharmacol Exp Ther 1994 269: 32-38. [Abstract] [PDF]  

JC Wurzer, RJ Tallarida, and MA Sirover

New mechanism of action of the cancer chemotherapeutic agent 5- fluorouracil in human cells
J Pharmacol Exp Ther 1994 269: 39-43. [Abstract] [PDF]  

I Terleckyj and PK Sonsalla

The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine- induced dopaminergic neurotoxicity via interactions at dopamine receptors
J Pharmacol Exp Ther 1994 269: 44-50. [Abstract] [PDF]  

A Sanbe, K Tanonaka, Y Niwano, and S Takeo

Improvement of cardiac function and myocardial energy metabolism of rats with chronic heart failure by long-term coenzyme Q10 treatment
J Pharmacol Exp Ther 1994 269: 51-56. [Abstract] [PDF]  

G Zernig, ER Butelman, JW Lewis, EA Walker, and JH Woods

In vivo determination of mu opioid receptor turnover in rhesus monkeys after irreversible blockade with clocinnamox
J Pharmacol Exp Ther 1994 269: 57-65. [Abstract] [PDF]  

MT Slawsky and NA Castle

K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes
J Pharmacol Exp Ther 1994 269: 66-74. [Abstract] [PDF]  

MJ Mangino, MK Murphy, and CB Anderson

Effects of the arachidonate 5-lipoxygenase synthesis inhibitor A-64077 in intestinal ischemia-reperfusion injury
J Pharmacol Exp Ther 1994 269: 75-81. [Abstract] [PDF]  

CK Jr Kost, WA Herzer, P Li, and EK Jackson

Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats
J Pharmacol Exp Ther 1994 269: 82-88. [Abstract] [PDF]  

PA Cossum, L Truong, SR Owens, PM Markham, JP Shea, and ST Crooke

Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats
J Pharmacol Exp Ther 1994 269: 89-94. [Abstract] [PDF]  

IA Paul, G Nowak, RT Layer, P Popik, and P Skolnick

Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments
J Pharmacol Exp Ther 1994 269: 95-102. [Abstract] [PDF]  

W Piekoszewski, FS Chow, and WJ Jusko

Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits
J Pharmacol Exp Ther 1994 269: 103-109. [Abstract] [PDF]  

K Bervoets and MJ Millan

5-HT1A receptors and the tail-flick response. V. Opposite modulation of 5-HT1A receptor-induced spontaneous tail-flicks by alpha 1A- as compared with alpha 2D-adrenoceptors in rat lumbar spinal cord
J Pharmacol Exp Ther 1994 269: 110-120. [Abstract] [PDF]  

MJ Millan, JM Rivet, A Gobert, H Canton, S Veiga, and K Bervoets

5-HT1A receptors and the tail-flick response. VI. Intrinsic alpha 1A- adrenoceptor antagonist properties can mask the actions of 5-HT1A receptor agonists in the spontaneous tail-flick paradigm
J Pharmacol Exp Ther 1994 269: 121-131. [Abstract] [PDF]  

RW Fuller, SK Hemrick-Luecke, and HD Snoddy

Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice
J Pharmacol Exp Ther 1994 269: 132-136. [Abstract] [PDF]  

TA Kosten, MJ Miserendino, S Chi, and EJ Nestler

Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion
J Pharmacol Exp Ther 1994 269: 137-144. [Abstract] [PDF]  

PA Bombardt, JE Brewer, and MG Johnson

Protein binding of tirilazad (U-74006) in human, Sprague-Dawley rat, beagle dog and cynomolgus monkey serum
J Pharmacol Exp Ther 1994 269: 145-150. [Abstract] [PDF]  

WE Perkins, RG Bianchi, SJ Tremont, PW Collins, JJ Casler, RL Fenton, GM Wagner, MP McGrath, JC Stolzenbach, and DL Kowalski

Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem
J Pharmacol Exp Ther 1994 269: 151-156. [Abstract] [PDF]  

W Marszalec, Y Kurata, BJ Hamilton, DB Carter, and T Narahashi

Selective effects of alcohols on gamma-aminobutyric acid A receptor subunits expressed in human embryonic kidney cells
J Pharmacol Exp Ther 1994 269: 157-163. [Abstract] [PDF]  

K Nagata and T Narahashi

Dual action of the cyclodiene insecticide dieldrin on the gamma- aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons
J Pharmacol Exp Ther 1994 269: 164-171. [Abstract] [PDF]  

M Babich, GE Alford, and RA Nissenson

A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells
J Pharmacol Exp Ther 1994 269: 172-177. [Abstract] [PDF]  

SK Mishra and K Hermsmeyer

Resting state block and use independence of rat vascular muscle Ca++ channels by Ro 40-5967
J Pharmacol Exp Ther 1994 269: 178-183. [Abstract] [PDF]  

JC Crabbe, JK Belknap, SR Mitchell, and LI Crawshaw

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice
J Pharmacol Exp Ther 1994 269: 184-192. [Abstract] [PDF]  

S Palea, M Corsi, C Pietra, W Artibani, A Calpista, G Gaviraghi, and DG Trist

ADP beta S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y
J Pharmacol Exp Ther 1994 269: 193-197. [Abstract] [PDF]  

CC Chao, G Gekker, WS Sheng, S Hu, M Tsang, and PK Peterson

Priming effect of morphine on the production of tumor necrosis factor- alpha by microglia: implications in respiratory burst activity and human immunodeficiency virus-1 expression
J Pharmacol Exp Ther 1994 269: 198-203. [Abstract] [PDF]  

RJ Ott, JK Chan, VK Ramanathan, AC Hui, and KM Giacomini

Effect of phenylisothiocyanate on organic cation transport in opossum kidney cells
J Pharmacol Exp Ther 1994 269: 204-208. [Abstract] [PDF]  

J Ren, E Karpinski, and CG Benishin

Inhibition of a K+ current by beta-dendrotoxin in primary and subcultured vascular smooth muscle cells
J Pharmacol Exp Ther 1994 269: 209-214. [Abstract] [PDF]  

AL Chamienia and EJ Johns

Renal functional responses to the 5-HT1A receptor agonist flesinoxan: effects of controlled renal perfusion pressure
J Pharmacol Exp Ther 1994 269: 215-220. [Abstract] [PDF]  

M Endou, E Poli, and R Levi

Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels
J Pharmacol Exp Ther 1994 269: 221-229. [Abstract] [PDF]  

ML Adams, ER Meyer, BN Sewing, and TJ Cicero

Effects of nitric oxide-related agents on rat testicular function
J Pharmacol Exp Ther 1994 269: 230-237. [Abstract] [PDF]  

P Salvati, L Dho, G Ukmar, L Vaga, O Rimoldi, and C Patrono

A comparative evaluation of thromboxane receptor blockade, thromboxane synthase inhibition and both in animal models of arterial thrombosis
J Pharmacol Exp Ther 1994 269: 238-245. [Abstract] [PDF]  

CD Unsworth and PB Molinoff

Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells
J Pharmacol Exp Ther 1994 269: 246-255. [Abstract] [PDF]  

LL Simpson, JA Coffield, and N Bakry

Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins
J Pharmacol Exp Ther 1994 269: 256-262. [Abstract] [PDF]  

AA Seymour, JH Sheldon, PL Smith, M Asaad, and WL Rogers

Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs
J Pharmacol Exp Ther 1994 269: 263-270. [Abstract] [PDF]  

HE Shannon, FP Bymaster, DO Calligaro, B Greenwood, CH Mitch, BD Sawyer, JS Ward, DT Wong, PH Olesen, and MJ Sheardown

Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors
J Pharmacol Exp Ther 1994 269: 271-281. [Abstract] [PDF]  

FP Bymaster, DT Wong, CH Mitch, JS Ward, DO Calligaro, DD Schoepp, HE Shannon, MJ Sheardown, PH Olesen, and PD Suzdak

Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232)
J Pharmacol Exp Ther 1994 269: 282-289. [Abstract] [PDF]  

CS Moravec, T Ruhe, JR Cifani, M Milovanovic, and PA Khairallah

Structural and functional consequences of minoxidil-induced cardiac hypertrophy
J Pharmacol Exp Ther 1994 269: 290-296. [Abstract] [PDF]  

MD Levitt and DG Levitt

The critical role of the rate of ethanol absorption in the interpretation of studies purporting to demonstrate gastric metabolism of ethanol
J Pharmacol Exp Ther 1994 269: 297-304. [Abstract] [PDF]  

RH Alper and MH 3rd Zink

Adrenergic and nonadrenergic regulation of hindlimb blood flow during stress in rats
J Pharmacol Exp Ther 1994 269: 305-312. [Abstract] [PDF]  

J Zhang, LA Chiodo, and AS Freeman

Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra
J Pharmacol Exp Ther 1994 269: 313-321. [Abstract] [PDF]  

SK Salzman, G Kelly, J Chavin, L Wang, MA Puniak, CA Agresta, and S Azim

Characterization of mianserin neuroprotection in experimental spinal trauma: dose/route response and late treatment
J Pharmacol Exp Ther 1994 269: 322-328. [Abstract] [PDF]  

RA Huff, JJ Corcoran, JK Anderson, and MB Abou-Donia

Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum
J Pharmacol Exp Ther 1994 269: 329-335. [Abstract] [PDF]  

A Zaza, G Malfatto, and PJ Schwartz

Diverse electrophysiologic effects of propafenone and flecainide in canine Purkinje fibers: implications for antiarrhythmic drug classification
J Pharmacol Exp Ther 1994 269: 336-343. [Abstract] [PDF]  

YS Kang and WM Pardridge

Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate
J Pharmacol Exp Ther 1994 269: 344-350. [Abstract] [PDF]  

L Cooke and KH Muntz

Differences in beta adrenergic receptor agonist affinity between cardiac myocytes and coronary arterioles in canine heart
J Pharmacol Exp Ther 1994 269: 351-357. [Abstract] [PDF]  

JB Long, DD Rigamonti, MA Oleshansky, CP Wingfield, and A Martinez-Arizala

Dynorphin A-induced rat spinal cord injury: evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury
J Pharmacol Exp Ther 1994 269: 358-366. [Abstract] [PDF]  

GM Adamson and RE Billings

Tumor necrosis factor: receptor binding and expression of receptors in cultured mouse hepatocytes
J Pharmacol Exp Ther 1994 269: 367-373. [Abstract] [PDF]  

LH Lash, PJ Sausen, RJ Duescher, AJ Cooley, and AA Elfarra

Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)- L-cysteine sulfoxide
J Pharmacol Exp Ther 1994 269: 374-383. [Abstract] [PDF]  

R Curi-Pedrosa, M Daujat, L Pichard, JC Ourlin, P Clair, L Gervot, P Lesca, J Domergue, H Joyeux, and G Fourtanier

Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture
J Pharmacol Exp Ther 1994 269: 384-392. [Abstract] [PDF]  

M Weller, AM Marini, B Martin, and SM Paul

The reduced unsubstituted pteroate moiety is required for folate toxicity of cultured cerebellar granule neurons
J Pharmacol Exp Ther 1994 269: 393-401. [Abstract] [PDF]  

RK Dubey

Vasodilator-derived nitric oxide inhibits fetal calf serum- and angiotensin-II-induced growth of renal arteriolar smooth muscle cells
J Pharmacol Exp Ther 1994 269: 402-408. [Abstract] [PDF]  

GE Billman

The effect of adrenergic receptor antagonists on cocaine-induced ventricular fibrillation: alpha but not beta adrenergic receptor antagonists prevent malignant arrhythmias independent of heart rate
J Pharmacol Exp Ther 1994 269: 409-416. [Abstract] [PDF]  

CJ Omiecinski, L Aicher, and L Swenson

Developmental expression of human microsomal epoxide hydrolase
J Pharmacol Exp Ther 1994 269: 417-423. [Abstract] [PDF]  

A Giacometti, D Micheli, G Gaviraghi, and DG Trist

Quantification of the calcium antagonism of lacidipine by kinetic analysis
J Pharmacol Exp Ther 1994 269: 424-429. [Abstract] [PDF]  

L Tesoriere, M Ciaccio, M Valenza, A Bongiorno, E Maresi, R Albiero, and MA Livrea

Effect of vitamin A administration on resistance of rat heart against doxorubicin-induced cardiotoxicity and lethality
J Pharmacol Exp Ther 1994 269: 430-436. [Abstract] [PDF]  

MA Klitenick and PW Kalivas

Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus
J Pharmacol Exp Ther 1994 269: 437-448. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1994 269: 449. [Abstract] [PDF]  

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