ARTICLES:

AS Gross and AA Somogyi

Interaction of the stereoisomers of basic drugs with the uptake of tetraethylammonium by rat renal brush-border membrane vesicles
J Pharmacol Exp Ther 1994 268: 1073-1080. [Abstract] [PDF]  

BK Taylor, D Holloway, and MP Printz

A unique central cholinergic deficit in the spontaneously hypertensive rat: physostigmine reveals a bradycardia associated with sensory stimulation
J Pharmacol Exp Ther 1994 268: 1081-1090. [Abstract] [PDF]  

DP Brooks, PD DePalma, M Pullen, and P Nambi

Characterization of canine renal endothelin receptor subtypes and their function
J Pharmacol Exp Ther 1994 268: 1091-1097. [Abstract] [PDF]  

MA Harrington, K Shaw, P Zhong, and RD Ciaranello

Agonist-induced desensitization and loss of high-affinity binding sites of stably expressed human 5-HT1A receptors
J Pharmacol Exp Ther 1994 268: 1098-1106. [Abstract] [PDF]  

Q Jiang, A Sebastian, S Archer, and JM Bidlack

5 beta-Methyl-14 beta-(p-nitrocinnamoylamino)-7,8-dihydromorphinone and its corresponding N-cyclopropylmethyl analog, N-cyclopropylmethylnor-5 beta-methyl-14 beta-(p-nitrocinnamoylamino)- 7,8-dihydromorphinone: mu- selective irreversible opioid antagonists
J Pharmacol Exp Ther 1994 268: 1107-1113. [Abstract] [PDF]  

S Liu, JS Beckman, and DD Ku

Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs
J Pharmacol Exp Ther 1994 268: 1114-1121. [Abstract] [PDF]  

S Mihara, S Nakajima, S Matumura, T Kohnoike, and M Fujimoto

Pharmacological characterization of a potent nonpeptide endothelin receptor antagonist, 97-139
J Pharmacol Exp Ther 1994 268: 1122-1128. [Abstract] [PDF]  

LR Flores, MC Hernandez, and BM Bayer

Acute immunosuppressive effects of morphine: lack of involvement of pituitary and adrenal factors
J Pharmacol Exp Ther 1994 268: 1129-1134. [Abstract] [PDF]  

X Xu and KS Lee

A selective blocker for rested T-type Ca++ channels in guinea pig atrial cells
J Pharmacol Exp Ther 1994 268: 1135-1142. [Abstract] [PDF]  

A Campos-Barros, H Meinhold, M Stula, F Muller, R Kohler, M Eravci, O Putzien, and A Baumgartner

The influence of desipramine on thyroid hormone metabolism in rat brain
J Pharmacol Exp Ther 1994 268: 1143-1152. [Abstract] [PDF]  

JQ Kong, DA Taylor, and WW Fleming

Functional distribution and role of alpha-1 adrenoceptor subtypes in the mesenteric vasculature of the rat
J Pharmacol Exp Ther 1994 268: 1153-1159. [Abstract] [PDF]  

GN Kumar, UK Walle, and T Walle

Cytochrome P450 3A-mediated human liver microsomal taxol 6 alpha- hydroxylation
J Pharmacol Exp Ther 1994 268: 1160-1165. [Abstract] [PDF]  

RJ Barrett, DA Droppleman, and KF Wright

Discrimination of A1 versus A2 receptor subtype selectivity of adenosine receptor agonists in vivo
J Pharmacol Exp Ther 1994 268: 1166-1173. [Abstract] [PDF]  

AP Williamson, E Seifen, JP Lindemann, and RH Kennedy

Effects of WB4101 and chloroethylclonidine on the positive and negative inotropic actions of phenylephrine in rat cardiac muscle
J Pharmacol Exp Ther 1994 268: 1174-1182. [Abstract] [PDF]  

PY Sze and Z Iqbal

Ethanol modulates [125I]calmodulin binding to synaptic plasma membranes from rat brain
J Pharmacol Exp Ther 1994 268: 1183-1189. [Abstract] [PDF]  

MJ Picker

Kappa agonist and antagonist properties of mixed action opioids in a pigeon drug discrimination procedure
J Pharmacol Exp Ther 1994 268: 1190-1198. [Abstract] [PDF]  

DD Christ, PC Wong, YN Wong, SD Hart, CY Quon, and GN Lam

The pharmacokinetics and pharmacodynamics of the angiotensin II receptor antagonist losartan potassium (DuP 753/MK 954) in the dog
J Pharmacol Exp Ther 1994 268: 1199-1205. [Abstract] [PDF]  

WL Hasler, HC Soudah, and C Owyang

Somatostatin analog inhibits afferent response to rectal distention in diarrhea-predominant irritable bowel patients
J Pharmacol Exp Ther 1994 268: 1206-1211. [Abstract] [PDF]  

E Kim, SN Giri, and IN Pessah

Antithetical actions of mitoxantrone and doxorubicin on ryanodine- sensitive Ca++ release channels of rat cardiac sarcoplasmic reticulum: evidence for a competitive mechanism
J Pharmacol Exp Ther 1994 268: 1212-1221. [Abstract] [PDF]  

JJ Rady, F Aksu, and JM Fujimoto

The heroin metabolite, 6-monoacetylmorphine, activates delta opioid receptors to produce antinociception in Swiss-Webster mice
J Pharmacol Exp Ther 1994 268: 1222-1231. [Abstract] [PDF]  

CP Cheng, T Noda, M Nordlander, M Ohno, and WC Little

Comparison of effects of dihydropyridine calcium antagonists on left ventricular systolic and diastolic performance
J Pharmacol Exp Ther 1994 268: 1232-1241. [Abstract] [PDF]  

G Eisenhofer and JP Finberg

Different metabolism of norepinephrine and epinephrine by catechol-O- methyltransferase and monoamine oxidase in rats
J Pharmacol Exp Ther 1994 268: 1242-1251. [Abstract] [PDF]  

G Rousseau, P Provost, D Tran, G Caille, and JG Latour

Clentiazem given at reperfusion improves subendocardial reflow and reduces myocardial infarct size in the dog
J Pharmacol Exp Ther 1994 268: 1252-1260. [Abstract] [PDF]  

LD Deleve

Dacarbazine toxicity in murine liver cells: a model of hepatic endothelial injury and glutathione defense
J Pharmacol Exp Ther 1994 268: 1261-1270. [Abstract] [PDF]  

DM Evans, JT Lake, MR Johnson, and AC Howlett

Endogenous cannabinoid receptor binding activity released from rat brain slices by depolarization
J Pharmacol Exp Ther 1994 268: 1271-1277. [Abstract] [PDF]  

LL von Moltke, DJ Greenblatt, MM Cotreau-Bibbo, SX Duan, JS Harmatz, and RI Shader

Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake- inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo
J Pharmacol Exp Ther 1994 268: 1278-1283. [Abstract] [PDF]  

CL Beauregard and PG Smith

Parasympathetic innervation of rat peri-orbital smooth muscle: prejunctional cholinergic inhibition of sympathetic neurotransmission without direct postjunctional actions
J Pharmacol Exp Ther 1994 268: 1284-1288. [Abstract] [PDF]  

S Diaz, S Specter, JY Vanderhoek, and RG Coffey

The effect of delta-9-tetrahydrocannabinol on arachidonic acid metabolism in human peripheral blood mononuclear cells
J Pharmacol Exp Ther 1994 268: 1289-1296. [Abstract] [PDF]  

MF Piercey, MW Smith, and JT Lum-Ragan

Excitation of noradrenergic cell firing by 5-hydroxytryptamine1A agonists correlates with dopamine antagonist properties
J Pharmacol Exp Ther 1994 268: 1297-1303. [Abstract] [PDF]  

MF Piercey, AH Tang, RA Lahti, PF VonVoigtlander, PJ Schreur, RB McCall, JT Lum- Ragan, WE Hoffmann, SR Franklin, and RA Code

Pharmacology of a mixed 5-hydroxytryptamine1A/dopamine agonist
J Pharmacol Exp Ther 1994 268: 1304-1310. [Abstract] [PDF]  

MA Mahajan and M Acara

Uptake and phosphorylation of thiamine in rat kidney cortical slices. I. Effect of ethanol
J Pharmacol Exp Ther 1994 268: 1311-1315. [Abstract] [PDF]  

MA Mahajan, M Acara, and M Taub

Uptake and phosphorylation of thiamine in rabbit primary proximal tubule cells and Madin Darby canine kidney cells. II. Effect of ethanol
J Pharmacol Exp Ther 1994 268: 1316-1320. [Abstract] [PDF]  

JS Fedan, JL Stem, and B Day

Contraction of the guinea pig isolated, perfused trachea to purine and pyrimidine agonists
J Pharmacol Exp Ther 1994 268: 1321-1327. [Abstract] [PDF]  

S Ali, SJ Mustafa, and WJ Metzger

Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor
J Pharmacol Exp Ther 1994 268: 1328-1334. [Abstract] [PDF]  

TJ Hudzik and DE McMillan

Drug effects on response-duration differentiation. II: Selective effects of antidepressant drugs
J Pharmacol Exp Ther 1994 268: 1335-1342. [Abstract] [PDF]  

AM el-Mowafy and AA Abdel-Latif

Characterization of iris sphincter smooth muscle endothelin receptor subtypes which are coupled to cyclic AMP formation and polyphosphoinositide hydrolysis
J Pharmacol Exp Ther 1994 268: 1343-1351. [Abstract] [PDF]  

SS Greenberg, A Johns, J Kleha, J Xie, Y Wang, J Bianchi, and K Conley

Phenol red is a thromboxane A2/prostaglandin H2 receptor antagonist in canine lingual arteries and human platelets
J Pharmacol Exp Ther 1994 268: 1352-1361. [Abstract] [PDF]  

MF O'Rourke, HS Blaxall, LJ Iversen, and DB Bylund

Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes
J Pharmacol Exp Ther 1994 268: 1362-1367. [Abstract] [PDF]  

MA Osinski and P Bass

Increased active stress generation of denervated rat intestinal smooth muscle: functional analysis of muscarinic receptor population
J Pharmacol Exp Ther 1994 268: 1368-1373. [Abstract] [PDF]  

R Crowther, D Jukic, D Regoli, and PK Rangachari

Functional subtyping of neurokinin receptors on canine proximal colonic mucosa
J Pharmacol Exp Ther 1994 268: 1374-1380. [Abstract] [PDF]  

PB Smith, SP Welch, and BR Martin

Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice
J Pharmacol Exp Ther 1994 268: 1381-1387. [Abstract] [PDF]  

JL Weiner, L Zhang, and PL Carlen

Potentiation of GABAA-mediated synaptic current by ethanol in hippocampal CA1 neurons: possible role of protein kinase C
J Pharmacol Exp Ther 1994 268: 1388-1395. [Abstract] [PDF]  

CARLOS BARAJAS-LÓPEZ, ROSA ESPINOSA-LUNA, and VLADIMIR GERZANICH

ATP Closes a Potassium and Opens a Cationic Conductance through Different Receptors in Neurons of Guinea Pig Submucous Plexus
J Pharmacol Exp Ther 1994 268: 1396-1402. [Abstract] [PDF]  

C Barajas-Lopez, R Espinosa-Luna, and V Gerzanich

ATP closes a potassium and opens a cationic conductance through different receptors in neurons of guinea pig submucous plexus
J Pharmacol Exp Ther 1994 268: 1397-1402. [Abstract]  

BL Roth, SC Craigo, MS Choudhary, A Uluer, FJ Jr Monsma, Y Shen, HY Meltzer, and DR Sibley

Binding of typical and atypical antipsychotic agents to 5- hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
J Pharmacol Exp Ther 1994 268: 1403-1410. [Abstract] [PDF]  

M Magnon, I Durand, and I Cavero

The contribution of guanylate cyclase stimulation and K+ channel opening to nicorandil-induced vasorelaxation depends on the conduit vessel and on the nature of the spasmogen
J Pharmacol Exp Ther 1994 268: 1411-1418. [Abstract] [PDF]  

E Petitclerc, PE Poubelle, and F Marceau

Rapid protein synthesis and turnover is involved in interleukin-1- induced relaxation of the rabbit isolated mesenteric artery. Analysis of the arachidonate cascade
J Pharmacol Exp Ther 1994 268: 1419-1425. [Abstract] [PDF]  

Z Li and SP Duckles

Influence of gender on vascular reactivity in the rat
J Pharmacol Exp Ther 1994 268: 1426-1431. [Abstract] [PDF]  

T Jolas, S Haj-Dahmane, EJ Kidd, X Langlois, L Lanfumey, CM Fattaccini, V Vantalon, AM Laporte, J Adrien, and H Gozlan

Central pre- and postsynaptic 5-HT1A receptors in rats treated chronically with a novel antidepressant, cericlamine
J Pharmacol Exp Ther 1994 268: 1432-1443. [Abstract] [PDF]  

M Berlan, J Galitzky, A Bousquet-Melou, M Lafontan, and JL Montastruc

Beta-3 adrenoceptor-mediated increase in cutaneous blood flow in the dog
J Pharmacol Exp Ther 1994 268: 1444-1451. [Abstract] [PDF]  

HY Meltzer, BL Chai, PA Thompson, and BK Yamamoto

Effect of scopolamine on the efflux of dopamine and its metabolites after clozapine, haloperidol or thioridazine
J Pharmacol Exp Ther 1994 268: 1452-1461. [Abstract] [PDF]  

HC Akunne, CM Dersch, JL Cadet, MH Baumann, GU Char, JS Partilla, BR de Costa, KC Rice, FI Carroll, and RB Rothman

Studies of the biogenic amine transporters. III. Demonstration of two binding sites for [3H]GBR12935 and [3H]BTCP in rat caudate membranes
J Pharmacol Exp Ther 1994 268: 1462-1475. [Abstract] [PDF]  

AM Vites and AJ Pappano

Distinct modes of inhibition by ruthenium red and ryanodine of calcium- induced calcium release in avian atrium
J Pharmacol Exp Ther 1994 268: 1476-1484. [Abstract] [PDF]  

X Lamas, M Farre, and J Cami

Acute effects of pentazocine, naloxone and morphine in opioid-dependent volunteers
J Pharmacol Exp Ther 1994 268: 1485-1492. [Abstract] [PDF]  

BS Tsai, RH Keith, D Villani-Price, RA Haack, and SW Djuric

The leukotriene B4 receptor agonist/antagonist activities of SC-45694 in human neutrophils
J Pharmacol Exp Ther 1994 268: 1493-1498. [Abstract] [PDF]  

BS Tsai, RH Keith, D Villani-Price, JF Kachur, DC Yang, SW Djuric, and S Yu

The in vitro pharmacology of SC-51146: a potent antagonist of leukotriene B4 receptors
J Pharmacol Exp Ther 1994 268: 1499-1505. [Abstract] [PDF]  

C Casati, A Monopoli, S Dionisotti, C Zocchi, E Bonizzoni, and E Ongini

Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects
J Pharmacol Exp Ther 1994 268: 1506-1511. [Abstract] [PDF]  

F Audebert, M Urtizberea, A Sabouraud, JM Scherrmann, and C Bon

Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits
J Pharmacol Exp Ther 1994 268: 1512-1517. [Abstract] [PDF]  

H Echizen, K Mochizuki, M Tani, and T Ishizaki

Interspecies differences in enantioselective mono-N-dealkylation of disopyramide by human and mouse liver microsomes
J Pharmacol Exp Ther 1994 268: 1518-1525. [Abstract] [PDF]  

A Ahluwalia and M Perretti

Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors
J Pharmacol Exp Ther 1994 268: 1526-1531. [Abstract] [PDF]  

GQ He, A Zhang, BT Altura, and BM Altura

Cocaine-induced cerebrovasospasm and its possible mechanism of action
J Pharmacol Exp Ther 1994 268: 1532-1539. [Abstract] [PDF]  

Y Inada, T Wada, Y Shibouta, M Ojima, T Sanada, K Ohtsuki, K Itoh, K Kubo, Y Kohara, and T Naka

Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1- (cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats
J Pharmacol Exp Ther 1994 268: 1540-1547. [Abstract] [PDF]  

MA Kling, DL Gardner, AE Calogero, R Coppola, J Trettau, CH Kellner, L Lefter, MJ Hart, RW Cowdry, and RM Post

Effects of local anesthetics on experiential, physiologic and endocrine measures in healthy humans and on rat hypothalamic corticotropin- releasing hormone release in vitro: clinical and psychobiologic implications
J Pharmacol Exp Ther 1994 268: 1548-1564. [Abstract] [PDF]  

PN Zannikos, AM Bandyopadhyay, LW Robertson, and RA Blouin

Cytochrome P450 2B enzyme induction defect after 2,2',4,4',5,5'- hexachlorobiphenyl treatment in the fa/fa Zucker rat
J Pharmacol Exp Ther 1994 268: 1565-1570. [Abstract] [PDF]  

JF Bowyer, DL Davies, L Schmued, HW Broening, GD Newport, W Jr Slikker, and RR Holson

Further studies of the role of hyperthermia in methamphetamine neurotoxicity
J Pharmacol Exp Ther 1994 268: 1571-1580. [Abstract] [PDF]  

O Binah, G Berke, D Rosen, and BF Hoffman

Calcium channel blockers modify electrophysiological effects induced by lytic granules from cytotoxic T lymphocytes in guinea pig ventricular myocytes
J Pharmacol Exp Ther 1994 268: 1581-1587. [Abstract] [PDF]  

DR Jr Blue, DA Craig, JT Ransom, JA Camacho, PA Insel, and DE Clarke

Characterization of the alpha-1 adrenoceptor subtype mediating [3H]- arachidonic acid release and calcium mobilization in Madin-Darby canine kidney cells
J Pharmacol Exp Ther 1994 268: 1588-1596. [Abstract] [PDF]  

T Watanabe, S Yuki, M Egawa, and H Nishi

Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions
J Pharmacol Exp Ther 1994 268: 1597-1604. [Abstract] [PDF]  

B Meister, A Dagerlind, AP Nicholas, and T Hokfelt

Patterns of messenger RNA expression for adrenergic receptor subtypes in the rat kidney
J Pharmacol Exp Ther 1994 268: 1605-1611. [Abstract] [PDF]  

AB Lynn and M Herkenham

Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids
J Pharmacol Exp Ther 1994 268: 1612-1623. [Abstract] [PDF]  

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