ARTICLES:

S Rosenzweig-Lipson and J Bergman

Modification of the behavioral effects of the selective dopamine D2 agonist (+)-4-propyl-9-hydroxynaphthoxazine by dopamine antagonists in monkeys
J Pharmacol Exp Ther 1993 265: 1039-1046. [Abstract] [PDF]  

SS Ahmed, HW Strobel, KL Napoli, and J Grevel

Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes
J Pharmacol Exp Ther 1993 265: 1047-1054. [Abstract] [PDF]  

J Willetts, DB Clissold, TL Hartman, RR Brandsgaard, GS Hamilton, and JW Ferkany

Behavioral pharmacology of NPC 17742, a competitive N-methyl-D- aspartate (NMDA) antagonist
J Pharmacol Exp Ther 1993 265: 1055-1062. [Abstract] [PDF]  

KG Steppuhn and L Turski

Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants
J Pharmacol Exp Ther 1993 265: 1063-1070. [Abstract] [PDF]  

DT Lysle, ME Coussons, VJ Watts, EH Bennett, and LA Dykstra

Morphine-induced alterations of immune status: dose dependency, compartment specificity and antagonism by naltrexone
J Pharmacol Exp Ther 1993 265: 1071-1078. [Abstract] [PDF]  

K Fecho, LA Dykstra, and DT Lysle

Evidence for beta adrenergic receptor involvement in the immunomodulatory effects of morphine
J Pharmacol Exp Ther 1993 265: 1079-1087. [Abstract] [PDF]  

PC Wong, PE Aldrich, AT Chiu, RA Earl, SD Hart, AL Johnson, P Ma, DE McCall, WA Jr Price, and RD Smith

Pharmacology of 2-amino-1,4-dihydro-4-(2-[4-[4-(2-methoxyphenyl)-1- piperazinyl]butylsulfinyl]phenyl)-6-methyl-5-nitro-3-pyridine carboxylic acid methyl ester (XB513), a novel calcium agonist with alpha-1 adrenergic receptor antagonistic
J Pharmacol Exp Ther 1993 265: 1088-1095. [Abstract] [PDF]  

DR Varma and S Chemtob

Endothelium- and beta-2 adrenoceptor-independent relaxation of rat aorta by tyramine and certain other phenylethylamines
J Pharmacol Exp Ther 1993 265: 1096-1104. [Abstract] [PDF]  

JE Shaffer, MK Grizzle, DK Anderson, and TN Wheeler

The inotropic and beta blocking effects of a chimeric molecule that putatively inhibits both type III phosphodiesterase and beta adrenoceptors in anesthetized dogs
J Pharmacol Exp Ther 1993 265: 1105-1112. [Abstract] [PDF]  

SH Pollock, MI Reichbaum, JC Colbert, PA Husain, JM Holbrook, AA Ogonowski, JS Khlief, and SW May

The oral antihypertensive activity of the methylated derivatives of phenyl-2-aminoethyl sulfide
J Pharmacol Exp Ther 1993 265: 1113-1117. [Abstract] [PDF]  

P Statkevich, DJ Fournier, and KR Sweeney

Characterization of methotrexate elimination and interaction with indomethacin and flurbiprofen in the isolated perfused rat kidney
J Pharmacol Exp Ther 1993 265: 1118-1124. [Abstract] [PDF]  

D Rampe, B Anderson, V Rapien-Pryor, T Li, and RC Dage

Comparison of the in vitro and in vivo cardiovascular effects of two structurally distinct Ca++ channel activators, BAY K 8644 and FPL 64176
J Pharmacol Exp Ther 1993 265: 1125-1130. [Abstract] [PDF]  

NL Kanagy and GD Fink

Losartan prevents salt-induced hypertension in reduced renal mass rats
J Pharmacol Exp Ther 1993 265: 1131-1136. [Abstract] [PDF]  

BR Shivakumar and V Ravindranath

Oxidative stress and thiol modification induced by chronic administration of haloperidol
J Pharmacol Exp Ther 1993 265: 1137-1141. [Abstract] [PDF]  

C Lugnier, B Muller, A Le Bec, C Beaudry, and E Rousseau

Characterization of indolidan- and rolipram-sensitive cyclic nucleotide phosphodiesterases in canine and human cardiac microsomal fractions
J Pharmacol Exp Ther 1993 265: 1142-1151. [Abstract] [PDF]  

JW Sloan, WR Martin, and E Wala

Effect of the chronic dose of diazepam on the intensity and characteristics of the precipitated abstinence syndrome in the dog
J Pharmacol Exp Ther 1993 265: 1152-1162. [Abstract] [PDF]  

RR Griffiths, SM Evans, JJ Guarino, JD Roache, WR Furman, I Liebson, and EM Schwam

Intravenous flumazenil following acute and repeated exposure to lorazepam in healthy volunteers: antagonism and precipitated withdrawal
J Pharmacol Exp Ther 1993 265: 1163-1174. [Abstract] [PDF]  

JA Calder, M Schachter, and PS Sever

Ion channel involvement in the acute vascular effects of thiazide diuretics and related compounds
J Pharmacol Exp Ther 1993 265: 1175-1180. [Abstract] [PDF]  

MI Glavinovic, JC Law Min, L Kapural, F Donati, and DR Bevan

Speed of action of various muscle relaxants at the neuromuscular junction binding vs. buffering hypothesis
J Pharmacol Exp Ther 1993 265: 1181-1186. [Abstract] [PDF]  

DL Luo, M Nakazawa, T Ishibashi, K Kato, and S Imai

Putative, selective inhibitors of sarcoplasmic reticulum Ca+(+)-pump ATPase inhibit relaxation by nitroglycerin and atrial natriuretic factor of the rabbit aorta contracted by phenylephrine
J Pharmacol Exp Ther 1993 265: 1187-1192. [Abstract] [PDF]  

TI Lidsky and SP Banerjee

Acute administration of haloperidol enhances dopaminergic transmission
J Pharmacol Exp Ther 1993 265: 1193-1198. [Abstract] [PDF]  

NW Fleming, BK Lewis, DA White, and KL Dretchen

Acute effects of calcitonin gene-related peptide on the mechanical and electrical responses of the rat hemidiaphragm
J Pharmacol Exp Ther 1993 265: 1199-1204. [Abstract] [PDF]  

A el Alj, N Winer, H Lallaoui, R Delansorne, F Ferre, and G Germain

Progesterone and mifepristone modify principally the responses of circular myometrium to oxytocin in preparturient rats: comparison with responses to acetylcholine and to calcium
J Pharmacol Exp Ther 1993 265: 1205-1212. [Abstract] [PDF]  

TJ Torphy, BJ Undem, LB Cieslinski, MA Luttmann, ML Reeves, and DW Hay

Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle
J Pharmacol Exp Ther 1993 265: 1213-1223. [Abstract] [PDF]  

S Giuliani, A Lecci, A Giachetti, and CA Maggi

Tachykinins and reflexly evoked atropine-resistant motility in the guinea pig colon in vivo
J Pharmacol Exp Ther 1993 265: 1224-1231. [Abstract] [PDF]  

RA Berg, JF Padbury, RL Donnerstein, SE Klewer, and JJ Jr Hutter

Dobutamine pharmacokinetics and pharmacodynamics in normal children and adolescents
J Pharmacol Exp Ther 1993 265: 1232-1238. [Abstract] [PDF]  

S Boesgaard, J Aldershvile, HE Poulsen, S Christensen, H Dige-Petersen, and J Giese

N-acetylcysteine inhibits angiotensin converting enzyme in vivo
J Pharmacol Exp Ther 1993 265: 1239-1244. [Abstract] [PDF]  

SS Negus, SJ Henriksen, A Mattox, GW Pasternak, PS Portoghese, AE Takemori, MB Weinger, and GF Koob

Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats
J Pharmacol Exp Ther 1993 265: 1245-1252. [Abstract] [PDF]  

VP Bakshi and AE Kelley

Feeding induced by opioid stimulation of the ventral striatum: role of opiate receptor subtypes
J Pharmacol Exp Ther 1993 265: 1253-1260. [Abstract] [PDF]  

SM Owens, M Gunnell, EM Laurenzana, and JL Valentine

Dose- and time-dependent changes in phencyclidine metabolite covalent binding in rats and the possible role of CYP2D1
J Pharmacol Exp Ther 1993 265: 1261-1266. [Abstract] [PDF]  

JA Bijlsma, HA Koomans, WH Boer, EJ Dorhout Mees, and HJ van Rijn

Indomethacin- and desamino-8-D-arginine vasopressin-induced lithium reabsorption is not amiloride sensitive in humans
J Pharmacol Exp Ther 1993 265: 1267-1271. [Abstract] [PDF]  

DL Nelson, VL Lucaites, JE Audia, JS Nissen, and DB Wainscott

Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines
J Pharmacol Exp Ther 1993 265: 1272-1279. [Abstract] [PDF]  

GN Pierce, WC Cole, K Liu, H Massaeli, TG Maddaford, YJ Chen, CD McPherson, S Jain, and D Sontag

Modulation of cardiac performance by amiloride and several selected derivatives of amiloride
J Pharmacol Exp Ther 1993 265: 1280-1291. [Abstract] [PDF]  

M Kohi, I Norota, M Takanashi, and M Endoh

On the mechanism of action of the beta-1 partial agonist denopamine in regulation of myocardial contractility: effects on myocardial alpha adrenoceptors and intracellular Ca++ transients
J Pharmacol Exp Ther 1993 265: 1292-1300. [Abstract] [PDF]  

K Sathirakul, H Suzuki, K Yasuda, M Hanano, O Tagaya, T Horie, and Y Sugiyama

Kinetic analysis of hepatobiliary transport of organic anions in Eisai hyperbilirubinemic mutant rats
J Pharmacol Exp Ther 1993 265: 1301-1312. [Abstract] [PDF]  

S Horie, S Yano, and K Watanabe

Inhibition of gastric acid secretion in vivo and in vitro by an inhibitor of Cl(-)-HCO3- exchanger, 4,4'-diisothiocyanostilbene-2,2'- disulfonic acid
J Pharmacol Exp Ther 1993 265: 1313-1318. [Abstract] [PDF]  

JJ Rutter and SB Auerbach

Acute uptake inhibition increases extracellular serotonin in the rat forebrain
J Pharmacol Exp Ther 1993 265: 1319-1324. [Abstract] [PDF]  

Y Miyamoto, PS Portoghese, and AE Takemori

Involvement of delta 2 opioid receptors in acute dependence on morphine in mice
J Pharmacol Exp Ther 1993 265: 1325-1327. [Abstract] [PDF]  

M Yakehiro, S Yamamoto, N Baba, S Nakajima, J Iwasa, and I Seyama

Structure-activity relationship for D-ring derivatives of grayanotoxin in the squid giant axon
J Pharmacol Exp Ther 1993 265: 1328-1332. [Abstract] [PDF]  

IP Chaudhary, S Tuntaterdtum, PJ McNamara, LW Robertson, and RA Blouin

Effect of genetic obesity and phenobarbital treatment on the hepatic conjugation pathways
J Pharmacol Exp Ther 1993 265: 1333-1338. [Abstract] [PDF]  

I Pham, W Gonzalez, AI el Amrani, MC Fournie-Zaluski, M Philippe, I Laboulandine, BP Roques, and JB Michel

Effects of converting enzyme inhibitor and neutral endopeptidase inhibitor on blood pressure and renal function in experimental hypertension
J Pharmacol Exp Ther 1993 265: 1339-1347. [Abstract] [PDF]  

CE Pendley, LR Fitzpatrick, RW Ewing, BF Molino, and GE Martin

The gastrin/cholecystokinin-B receptor antagonist L-365,260 reduces basal acid secretion and prevents gastrointestinal damage induced by aspirin, ethanol and cysteamine in the rat
J Pharmacol Exp Ther 1993 265: 1348-1354. [Abstract] [PDF]  

DP Rodeheaver and RG Schnellmann

Extracellular acidosis ameliorates metabolic-inhibitor-induced and potentiates oxidant-induced cell death in renal proximal tubules
J Pharmacol Exp Ther 1993 265: 1355-1360. [Abstract] [PDF]  

FS Wang and JM Fujimoto

Pentobarbital administered intracerebroventricularly antagonizes morphine-induced antinociception in mice
J Pharmacol Exp Ther 1993 265: 1361-1368. [Abstract] [PDF]  

M Dikshit, R Kumari, and RC Srimal

Pulmonary thromboembolism-induced alterations in nitric oxide release from rat circulating neutrophils
J Pharmacol Exp Ther 1993 265: 1369-1373. [Abstract] [PDF]  

DA Finn and KW Gee

The influence of estrus cycle on neurosteroid potency at the gamma- aminobutyric acidA receptor complex
J Pharmacol Exp Ther 1993 265: 1374-1379. [Abstract] [PDF]  

G Nowak, R Trullas, RT Layer, P Skolnick, and IA Paul

Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid
J Pharmacol Exp Ther 1993 265: 1380-1386. [Abstract] [PDF]  

EF Domino and J Sheng

Relative potency and efficacy of some dopamine agonists with varying selectivities for D1 and D2 receptors in MPTP-induced hemiparkinsonian monkeys [published erratum appears in J Pharmacol Exp Ther 1993 Oct;267(1):566]
J Pharmacol Exp Ther 1993 265: 1387-1391. [Abstract] [PDF]  

B Harris, G Wong, and P Skolnick

Neurochemical actions of inhalational anesthetics at the GABAA receptor complex
J Pharmacol Exp Ther 1993 265: 1392-1398. [Abstract] [PDF]  

NJ Lodge and NN Halaka

8-(Diethylamino)-octyl-3,4,5-trimethoxybenzoate inhibits cromakalim- induced 86Rb efflux from the rat aorta
J Pharmacol Exp Ther 1993 265: 1399-1405. [Abstract] [PDF]  

M Polhuijs, I Gasinska, WF Cherry, GJ Mulder, and KS Pang

Stereoselectivity in glutathione conjugation and amidase-catalyzed hydrolysis of the 2-bromoisovalerylurea enantiomers in the single-pass perfused rat liver
J Pharmacol Exp Ther 1993 265: 1406-1412. [Abstract] [PDF]  

J 3d Fulginiti, MM Cohen, and RS Moreland

Endothelin differentially affects rat gastric longitudinal and circular smooth muscle
J Pharmacol Exp Ther 1993 265: 1413-1420. [Abstract] [PDF]  

HR Brady, ML Zeidel, BC Kone, G Giebisch, and SR Gullans

Differential actions of cisplatin on renal proximal tubule and inner medullary collecting duct cells
J Pharmacol Exp Ther 1993 265: 1421-1428. [Abstract] [PDF]  

MV St-Pierre and KS Pang

Kinetics of sequential metabolism. I. Formation and metabolism of oxazepam from nordiazepam and temazepam in the perfused murine liver
J Pharmacol Exp Ther 1993 265: 1429-1436. [Abstract] [PDF]  

MV St-Pierre and KS Pang

Kinetics of sequential metabolism. II. Formation and metabolism of nordiazepam and oxazepam from diazepam in the perfused murine liver
J Pharmacol Exp Ther 1993 265: 1437-1445. [Abstract] [PDF]  

PJ Horan, A Mattia, EJ Bilsky, S Weber, TP Davis, HI Yamamura, E Malatynska, SM Appleyard, J Slaninova, and A Misicka

Antinociceptive profile of biphalin, a dimeric enkephalin analog
J Pharmacol Exp Ther 1993 265: 1446-1454. [Abstract] [PDF]  

NA Castle and MT Slawsky

Characterization of 4-aminopyridine block of the transient outward K+ current in adult rat ventricular myocytes [corrected and republished with original paging, article originally printed in J Pharmacol Exp Ther 1993 Mar;264(3):1450-9]
J Pharmacol Exp Ther 1993 265: 1450-1459. [Abstract]  

M Alkondon and EX Albuquerque

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes
J Pharmacol Exp Ther 1993 265: 1455-1473. [Abstract] [PDF]  

EF Pereira, S Reinhardt-Maelicke, A Schrattenholz, A Maelicke, and EX Albuquerque

Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons
J Pharmacol Exp Ther 1993 265: 1474-1491. [Abstract] [PDF]  

J Llorens, KM Crofton, and JP O'Callaghan

Administration of 3,3'-iminodipropionitrile to the rat results in region-dependent damage to the central nervous system at levels above the brain stem
J Pharmacol Exp Ther 1993 265: 1492-1498. [Abstract] [PDF]  

M Flezar and S Heisler

P2-purinergic receptors in human breast tumor cells: coupling of intracellular calcium signaling to anion secretion
J Pharmacol Exp Ther 1993 265: 1499-1510. [Abstract] [PDF]  

CJ Tseng, M Appalsamy, D Robertson, and R Mosqueda-Garcia

Effects of nicotine on brain stem mechanisms of cardiovascular control
J Pharmacol Exp Ther 1993 265: 1511-1518. [Abstract] [PDF]  

SL Cruz, LA Salazar, A Fernandez-Guasti, and JE Villarreal

Quantitative analysis of concentration-response curves for precipitated abstinence responses in the opiate-dependent guinea pig ileum
J Pharmacol Exp Ther 1993 265: 1519-1526. [Abstract] [PDF]  

S Hayashi, M Horie, and Y Okada

Ionic mechanism of minoxidil sulfate-induced shortening of action potential durations in guinea pig ventricular myocytes
J Pharmacol Exp Ther 1993 265: 1527-1533. [Abstract] [PDF]  

D Chansel, L Badre, S Czekalski, S Vandermeersch, J Cambar, and R Ardaillou

Intrinsic properties of the nonpeptide angiotensin II antagonist losartan in glomeruli and mesangial cells at high concentrations
J Pharmacol Exp Ther 1993 265: 1534-1543. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1993 265: 15661. [Abstract] [PDF]  

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