ARTICLES:

S Yasar, CW Schindler, EB Thorndike, I Szelenyi, and SR Goldberg

Evaluation of the stereoisomers of deprenyl for amphetamine-like discriminative stimulus effects in rats
J Pharmacol Exp Ther 1993 265: 1-6. [Abstract] [PDF]  

P Blier, A Lista, and C De Montigny

Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone
J Pharmacol Exp Ther 1993 265: 7-15. [Abstract] [PDF]  

P Blier, A Lista, and C De Montigny

Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: II. Effect of pertussis and cholera toxins
J Pharmacol Exp Ther 1993 265: 16-23. [Abstract] [PDF]  

RP Simon, J Chen, and SH Graham

GM1 ganglioside treatment of focal ischemia: a dose-response and microdialysis study
J Pharmacol Exp Ther 1993 265: 24-29. [Abstract] [PDF]  

RD Bukoski, J Bo, H Xue, and K Bian

Antiproliferative and endothelium-dependent vasodilator properties of 1,3-dihydro-3-p-chlorophenyl-7-hydroxy-6-methyl-furo-(3,4c) pyridine hydrochloride (cicletanine)
J Pharmacol Exp Ther 1993 265: 30-35. [Abstract] [PDF]  

G Piedimonte, JI Hoffman, WK Husseini, C Bertrand, RM Snider, MC Desai, G Petersson, and JA Nadel

Neurogenic vasodilation in the rat nasal mucosa involves neurokinin1 tachykinin receptors
J Pharmacol Exp Ther 1993 265: 36-40. [Abstract] [PDF]  

M Okamoto, LJ Viskatis, G de la Roza, and JC Vidal

Induction of tolerance to crotoxin in mice
J Pharmacol Exp Ther 1993 265: 41-46. [Abstract] [PDF]  

RJ Lamb and RR Griffiths

Behavioral effects of pentobarbital, lorazepam, ethanol and chlorpromazine substitution in pentobarbital-dependent baboons
J Pharmacol Exp Ther 1993 265: 47-52. [Abstract] [PDF]  

TS Shippenberg, R Bals-Kubik, and A Herz

Examination of the neurochemical substrates mediating the motivational effects of opioids: role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors
J Pharmacol Exp Ther 1993 265: 53-59. [Abstract] [PDF]  

PP Sokol, KL Longenecker, DL Kachel, and WJ 2d Martin

Mechanism of putrescine transport in human pulmonary artery endothelial cells
J Pharmacol Exp Ther 1993 265: 60-66. [Abstract] [PDF]  

K Raynor, I Lucki, and T Reisine

Somatostatin receptors in the nucleus accumbens selectively mediate the stimulatory effect of somatostatin on locomotor activity in rats
J Pharmacol Exp Ther 1993 265: 67-73. [Abstract] [PDF]  

JC Sill, S Eskuri, R Nelson, J Tarara, and RA Van Dyke

The volatile anesthetic isoflurane attenuates Ca++ mobilization in cultured vascular smooth muscle cells
J Pharmacol Exp Ther 1993 265: 74-80. [Abstract] [PDF]  

DO Freier and BA Fuchs

Morphine-induced alterations in thymocyte subpopulations of B6C3F1 mice
J Pharmacol Exp Ther 1993 265: 81-88. [Abstract] [PDF]  

SC Baraban, RL Stornetta, and PG Guyenet

Respiratory control of sympathetic nerve activity during naloxone- precipitated morphine withdrawal in rats
J Pharmacol Exp Ther 1993 265: 89-95. [Abstract] [PDF]  

M Million, J Fioramonti, S Gicquel, JM Zajac, and L Bueno

Comparative action of Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 analogs on intestinal motility and nociception in rats
J Pharmacol Exp Ther 1993 265: 96-102. [Abstract] [PDF]  

A Colzi, F D'Agostini, AM Cesura, E Borroni, and M Da Prada

Monoamine oxidase-A inhibitors and dopamine metabolism in rat caudatus: evidence that an increased cytosolic level of dopamine displaces reversible monoamine oxidase-A inhibitors in vivo
J Pharmacol Exp Ther 1993 265: 103-111. [Abstract] [PDF]  

YX Wang, CI Poon, and CC Pang

In vitro and ex vivo inhibitory effects of L- and D-enantiomers of NG- nitro-arginine on endothelium-dependent relaxation of rat aorta
J Pharmacol Exp Ther 1993 265: 112-119. [Abstract] [PDF]  

TJ Hudzik and GR Wenger

Effects of drugs of abuse and cholinergic agents on delayed matching-to- sample responding in the squirrel monkey
J Pharmacol Exp Ther 1993 265: 120-127. [Abstract] [PDF]  

SL Cruz and JE Villarreal

Acute opioid dependence in the cardiovascular system of the spinal rat
J Pharmacol Exp Ther 1993 265: 128-133. [Abstract] [PDF]  

DR Kapusta, JC Obih, and GF Dibona

Central mu opioid receptor-mediated changes in renal function in conscious rats
J Pharmacol Exp Ther 1993 265: 134-143. [Abstract] [PDF]  

LA Burns and AE Munson

Reversal of gallium arsenide-induced suppression of the antibody- forming cell response by vehicle supernatants. I. Pharmacokinetics after in vitro and in vivo exposure
J Pharmacol Exp Ther 1993 265: 144-149. [Abstract] [PDF]  

LA Burns and AE Munson

Reversal of gallium arsenide-induced suppression of the antibody- forming cell response by vehicle supernatants. II. Nature and identification of reversing factors
J Pharmacol Exp Ther 1993 265: 150-158. [Abstract] [PDF]  

AA Larson and X Sun

Modulation of kainic acid-induced activity in the mouse spinal cord by the amino terminus of substance P: sensitivity to opioid antagonists
J Pharmacol Exp Ther 1993 265: 159-165. [Abstract] [PDF]  

CG Pick, RJ Nejat, and GW Pasternak

Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains
J Pharmacol Exp Ther 1993 265: 166-171. [Abstract] [PDF]  

RE Tessel, DW Miller, GA Misse, X Dong, and MB Doughty

Characterization of vascular postsynaptic neuropeptide Y receptor function and regulation. 1. NPY-induced constriction in isolated rat femoral artery rings is mediated by both Y1 and Y2 receptors: evidence from benextramine protection studies
J Pharmacol Exp Ther 1993 265: 172-177. [Abstract] [PDF]  

LA Burns and AE Munson

Gallium arsenide selectively inhibits T cell proliferation and alters expression of CD25 (IL-2R/p55)
J Pharmacol Exp Ther 1993 265: 178-186. [Abstract] [PDF]  

TC Major, RW Overhiser, DG Jr Taylor, and RL Panek

Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats
J Pharmacol Exp Ther 1993 265: 187-193. [Abstract] [PDF]  

SB Backman, M Bachoo, and C Polosa

Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine
J Pharmacol Exp Ther 1993 265: 194-200. [Abstract] [PDF]  

PL Martin, AA Potts, AM Sykes, and DG McKenna

(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria
J Pharmacol Exp Ther 1993 265: 201-206. [Abstract] [PDF]  

BS Neal-Beliveau, JN Joyce, and I Lucki

Serotonergic involvement in haloperidol-induced catalepsy
J Pharmacol Exp Ther 1993 265: 207-217. [Abstract] [PDF]  

DR Compton, KC Rice, BR De Costa, RK Razdan, LS Melvin, MR Johnson, and BR Martin

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities
J Pharmacol Exp Ther 1993 265: 218-226. [Abstract] [PDF]  

RJ Barrett, JM May, PL Martin, and JR Miller

In vitro and in vivo pharmacological characterization of N6-cyclopentyl- 9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist
J Pharmacol Exp Ther 1993 265: 227-236. [Abstract] [PDF]  

C Carpene, J Galitzky, P Collon, F Esclapez, M Dauzats, and M Lafontan

Desensitization of beta-1 and beta-2, but not beta-3, adrenoceptor- mediated lipolytic responses of adipocytes after long-term norepinephrine infusion
J Pharmacol Exp Ther 1993 265: 237-247. [Abstract] [PDF]  

PL Martin, M Ueeda, and RA Olsson

2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig
J Pharmacol Exp Ther 1993 265: 248-253. [Abstract] [PDF]  

JE Zadina, SL Chang, LJ Ge, and AJ Kastin

Mu opiate receptor down-regulation by morphine and up-regulation by naloxone in SH-SY5Y human neuroblastoma cells
J Pharmacol Exp Ther 1993 265: 254-262. [Abstract] [PDF]  

YX Wang and CC Pang

Functional integrity of the central and sympathetic nervous systems is a prerequisite for pressor and tachycardic effects of diphenyleneiodonium, a novel inhibitor of nitric oxide synthase
J Pharmacol Exp Ther 1993 265: 263-272. [Abstract] [PDF]  

G Sprakties, HJ Macherey, and KU Petersen

Secretin and somatostatin as modulators of electrolyte transport in guinea pig gallbladder epithelium
J Pharmacol Exp Ther 1993 265: 273-280. [Abstract] [PDF]  

JM Mathews and JR Bend

N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme- selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo
J Pharmacol Exp Ther 1993 265: 281-285. [Abstract] [PDF]  

S Parvini, SR Hamann, and WR Martin

Pharmacologic characteristics of a medullary hyperalgesic center
J Pharmacol Exp Ther 1993 265: 286-293. [Abstract] [PDF]  

RJ Lukas

Expression of ganglia-type nicotinic acetylcholine receptors and nicotinic ligand binding sites by cells of the IMR-32 human neuroblastoma clonal line
J Pharmacol Exp Ther 1993 265: 294-302. [Abstract] [PDF]  

JL Goudreau, J Manzanares, KJ Lookingland, and KE Moore

5HT2 receptors mediate the effects of stress on the activity of periventricular hypophysial dopaminergic neurons and the secretion of alpha-melanocyte-stimulating hormone
J Pharmacol Exp Ther 1993 265: 303-307. [Abstract] [PDF]  

L Wang, MR Lucey, AM Fras, EJ Wilson, and J Del Valle

Epidermal growth factor and transforming growth factor-alpha directly inhibit parietal cell function through a similar mechanism
J Pharmacol Exp Ther 1993 265: 308-313. [Abstract] [PDF]  

BC Yoburn, B Billings, and A Duttaroy

Opioid receptor regulation in mice
J Pharmacol Exp Ther 1993 265: 314-320. [Abstract] [PDF]  

CA Yiamouyiannis, BJ Martin, and JB 3d Watkins

Chronic physical activity alters hepatobiliary excretory function in rats
J Pharmacol Exp Ther 1993 265: 321-327. [Abstract] [PDF]  

T Imai, A Fukuhara, I Ueda, and M Otagiri

An evaluation of an anti-inflammatory-histamine H2 antagonist drug complex on gastric erosions in the rat
J Pharmacol Exp Ther 1993 265: 328-333. [Abstract] [PDF]  

PC Churchill and VR Ellis

Pharmacological characterization of the renovascular P2 purinergic receptors
J Pharmacol Exp Ther 1993 265: 334-338. [Abstract] [PDF]  

FY Chen and TJ Lee

Role of nitric oxide in neurogenic vasodilation of porcine cerebral artery
J Pharmacol Exp Ther 1993 265: 339-345. [Abstract] [PDF]  

RH Schwinger, M Bohm, C Schulz, U Schmidt, U Schmidt, B Schmid, H Dienemann, B Reichart, and E Erdmann

Cardiac inotropic as well as coronary and pulmonary artery actions of epinine in human isolated tissues
J Pharmacol Exp Ther 1993 265: 346-357. [Abstract] [PDF]  

JJ Pancrazio, MJ Frazer, and C 3d Lynch

Barbiturate anesthetics depress the resting K+ conductance of myocardium
J Pharmacol Exp Ther 1993 265: 358-365. [Abstract] [PDF]  

A Berson, C Wolf, C Chachaty, C Fisch, D Fau, D Eugene, J Loeper, JC Gauthier, P Beaune, and D Pompon

Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies
J Pharmacol Exp Ther 1993 265: 366-372. [Abstract] [PDF]  

S Benloucif, MJ Keegan, and MP Galloway

Serotonin-facilitated dopamine release in vivo: pharmacological characterization
J Pharmacol Exp Ther 1993 265: 373-377. [Abstract] [PDF]  

AA Alhaider and GL Wilcox

Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice
J Pharmacol Exp Ther 1993 265: 378-385. [Abstract] [PDF]  

RD Verschoyle, D Dinsdale, and CR Wolf

Inhibition and induction of cytochrome P450 isoenzymes in rat lung
J Pharmacol Exp Ther 1993 265: 386-391. [Abstract] [PDF]  

R Imberti, AL Nieminen, B Herman, and JJ Lemasters

Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine
J Pharmacol Exp Ther 1993 265: 392-400. [Abstract] [PDF]  

W Tassaneeyakul, DJ Birkett, ME Veronese, ME McManus, RH Tukey, LC Quattrochi, HV Gelboin, and JO Miners

Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2
J Pharmacol Exp Ther 1993 265: 401-407. [Abstract] [PDF]  

SF Rosebrough

Plasma stability and pharmacokinetics of radiolabeled deferoxamine- biotin derivatives
J Pharmacol Exp Ther 1993 265: 408-415. [Abstract] [PDF]  

P Tagari, A Becker, C Brideau, R Frenette, V Sadl, E Thomas, P Vickers, and A Ford- Hutchinson

Leukotriene generation and metabolism in dogs: inhibition of biosynthesis by MK-0591
J Pharmacol Exp Ther 1993 265: 416-425. [Abstract] [PDF]  

AM Lin, RK Freund, and MR Palmer

Sensitization of gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons to the potentiative effects of ethanol by beta adrenergic mechanisms in rat brain
J Pharmacol Exp Ther 1993 265: 426-432. [Abstract] [PDF]  

JG Contrera, SW Mcleskey, I Holopainen, J Xu, and WJ Wojcik

Muscarinic m2 receptors in cerebellar granule cell cultures from rat: mechanism of short-term desensitization
J Pharmacol Exp Ther 1993 265: 433-440. [Abstract] [PDF]  

P Longone, I Mocchetti, MA Riva, and WJ Wojcik

Characterization of a decrease in muscarinic m2 mRNA in cerebellar granule cells by carbachol
J Pharmacol Exp Ther 1993 265: 441-446. [Abstract] [PDF]  

GW 2d Dorn and MW Becker

Thromboxane A2 stimulated signal transduction in vascular smooth muscle
J Pharmacol Exp Ther 1993 265: 447-456. [Abstract] [PDF]  

CW Benjamin, AH Lin, J Morris, DG Wishka, and RR Gorman

2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity
J Pharmacol Exp Ther 1993 265: 457-462. [Abstract] [PDF]  

T Gemba, M Ninomiya, K Matsunaga, and M Ueda

Effects of a novel calcium antagonist, S-(+)-methyl-4,7-dihydro-3- isobutyl-6- methyl-4-(3-nitrophenyl)thieno[2,3-b]pyridine-5-carboxylate (S-312-d), on ischemic amino acid release and neuronal injury in stroke- prone spontaneously hypertensive rats
J Pharmacol Exp Ther 1993 265: 463-467. [Abstract] [PDF]  

ZK Krowicki and PJ Hornby

Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway
J Pharmacol Exp Ther 1993 265: 468-476. [Abstract] [PDF]  

M Murray, E Cantrill, and GC Farrell

Induction of cytochrome P450 2B1 in rat liver by the aromatase inhibitor aminoglutethimide
J Pharmacol Exp Ther 1993 265: 477-481. [Abstract] [PDF]  

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