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January 1993; 264 (1)   [Index by Author]       Other Issues:  
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Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |
To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

ARTICLES:

E Donato di Paola, B Cusack, M Yamada, and E Richelson
Desensitization and down-regulation of neurotensin receptors in murine neuroblastoma clone N1E-115 by [D-Lys8] neurotensin(8-13)
J Pharmacol Exp Ther 1993 264: 1-5. [Abstract] [PDF]  

GL DeGraaf, DT Pals, SJ Couch, and JA Lawson
Hormonal and cardiovascular effects of losartan (DuP753), an angiotensin receptor antagonist, in nonhuman primates
J Pharmacol Exp Ther 1993 264: 6-10. [Abstract] [PDF]  

MJ Miller, H Sadowska-Krowicka, S Chotinaruemol, JL Kakkis, and DA Clark
Amelioration of chronic ileitis by nitric oxide synthase inhibition
J Pharmacol Exp Ther 1993 264: 11-16. [Abstract] [PDF]  

R Patacchini, L Quartara, P Rovero, C Goso, and CA Maggi
Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties
J Pharmacol Exp Ther 1993 264: 17-21. [Abstract] [PDF]  

E Reuveny, DA Twombly, and T Narahashi
Chlordiazepoxide block of two types of calcium channels in neuroblastoma cells
J Pharmacol Exp Ther 1993 264: 22-28. [Abstract] [PDF]  

TS King, MS Canez, S Gaskill, MA Javors, and RS Schenken
Chronic cocaine disruption of estrous cyclicity in the rat: dose- dependent effects
J Pharmacol Exp Ther 1993 264: 29-34. [Abstract] [PDF]  

M Ohta, J Nelson, D Nelson, MD Meglasson, and M Erecinska
Effect of Ca++ channel blockers on energy level and stimulated insulin secretion in isolated rat islets of Langerhans
J Pharmacol Exp Ther 1993 264: 35-40. [Abstract] [PDF]  

IY Hwang and AA Elfarra
Detection and mechanisms of formation of S-(6-purinyl)glutathione and 6- mercaptopurine in rats given 6-chloropurine
J Pharmacol Exp Ther 1993 264: 41-46. [Abstract] [PDF]  

TJ Cicero, B Nock, and L O'Connor
Naloxone does not reverse the inhibitory effect of morphine on luteinizing hormone secretion in prepubescent male rats
J Pharmacol Exp Ther 1993 264: 47-53. [Abstract] [PDF]  

K Yokotani and Y Osumi
Cholinergic M2 muscarinic receptor-mediated inhibition of endogenous noradrenaline release from the isolated vascularly perfused rat stomach
J Pharmacol Exp Ther 1993 264: 54-60. [Abstract] [PDF]  

TR Traynor, DR Brown, and SM O'Grady
Effects of inflammatory mediators on electrolyte transport across the porcine distal colon epithelium
J Pharmacol Exp Ther 1993 264: 61-66. [Abstract] [PDF]  

GR Thomas, H Thibodeaux, WF Bennett, CJ Refino, JM Badillo, CJ Errett, and JA Zivin
Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke
J Pharmacol Exp Ther 1993 264: 67-73. [Abstract] [PDF]  

M McKinney, JH Miller, and PJ Aagaard
Pharmacological characterization of the rat hippocampal muscarinic autoreceptor
J Pharmacol Exp Ther 1993 264: 74-78. [Abstract] [PDF]  

WJ de Ridder and JA Schuurkes
Cisapride and 5-hydroxytryptamine enhance motility in the canine antrum via separate pathways, not involving 5-hydroxytryptamine1,2,3,4 receptors
J Pharmacol Exp Ther 1993 264: 79-88. [Abstract] [PDF]  

T Yasumori, L Chen, K Nagata, Y Yamazoe, and R Kato
Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A)
J Pharmacol Exp Ther 1993 264: 89-94. [Abstract] [PDF]  

K Bervoets, JM Rivet, and MJ Millan
5-HT1A receptors and the tail-flick response. IV. Spinally localized 5- HT1A receptors postsynaptic to serotoninergic neurones mediate spontaneous tail-flicks in the rat
J Pharmacol Exp Ther 1993 264: 95-104. [Abstract] [PDF]  

S Homma, E Kusano, S Takeda, N Murayama, Y Asano, and TP Dousa
Both beta-1 and beta-2 adrenoceptors are coupled to the cyclic AMP system in connecting tubules of rabbit nephron
J Pharmacol Exp Ther 1993 264: 105-109. [Abstract] [PDF]  

K Raynor and T Reisine
Subtypes of somatostatin receptors are expressed in the anterior pituitary cell line GH3
J Pharmacol Exp Ther 1993 264: 110-116. [Abstract] [PDF]  

A Ogasawara, H Hisa, and S Satoh
An intracellular calcium release inhibitor TMB-8 suppresses renal nerve stimulation-induced antinatriuresis in dogs
J Pharmacol Exp Ther 1993 264: 117-121. [Abstract] [PDF]  

K Ichihara, T Nabeshima, and T Kameyama
Dopaminergic agonists impair latent learning in mice: possible modulation by noradrenergic function
J Pharmacol Exp Ther 1993 264: 122-128. [Abstract] [PDF]  

G Balasubramaniam, HS Lee, and SC Mah
Differences in the acute and chronic antihypertensive mechanism of action of ketanserin in spontaneously hypertensive rats
J Pharmacol Exp Ther 1993 264: 129-134. [Abstract] [PDF]  

GD Lopaschuk, RB Wambolt, and RL Barr
An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts
J Pharmacol Exp Ther 1993 264: 135-144. [Abstract] [PDF]  

ER Butelman, CP France, and JH Woods
Apparent pA2 analysis on the respiratory depressant effects of alfentanil, etonitazene, ethylketocyclazocine (EKC) and Mr2033 in rhesus monkeys
J Pharmacol Exp Ther 1993 264: 145-151. [Abstract] [PDF]  

S Ueki, M Seiki, T Yoneta, H Aita, K Chaki, Y Hori, H Morita, E Tagashira, and Z Itoh
Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats
J Pharmacol Exp Ther 1993 264: 152-157. [Abstract] [PDF]  

M Oka, Y Noda, Y Ochi, K Furukawa, T Une, S Kurumiya, K Hino, and T Karasawa
Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties
J Pharmacol Exp Ther 1993 264: 158-165. [Abstract] [PDF]  

Y Imamura, K Iwamoto, Y Yanachi, T Higuchi, and M Otagiri
Postnatal development, sex-related difference and hormonal regulation of acetohexamide reductase activities in rat liver and kidney
J Pharmacol Exp Ther 1993 264: 166-171. [Abstract] [PDF]  

P Ernsberger, TH Damon, LM Graff, SG Schafer, and MO Christen
Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites
J Pharmacol Exp Ther 1993 264: 172-182. [Abstract] [PDF]  

JL Katz, JW Griffiths, LG Sharpe, EB De Souza, and JM Witkin
Cocaine tolerance and cross-tolerance
J Pharmacol Exp Ther 1993 264: 183-192. [Abstract] [PDF]  

DJ Cushing and ML Cohen
Serotonin-induced contraction in porcine coronary artery: use of ergolines to support vascular 5-hydroxytryptamine2-receptor heterogeneity
J Pharmacol Exp Ther 1993 264: 193-200. [Abstract] [PDF]  

Y Shimamoto, H Shimamoto, CY Kwan, and EE Daniel
Rauwolscine induces contraction in the dog mesenteric artery precontracted with KCl and endothelin-1: mediation via 5- hydroxytryptamine1-like receptors
J Pharmacol Exp Ther 1993 264: 201-209. [Abstract] [PDF]  

JS Fedan, JJ Belt, LX Yuan, and DG Frazer
Contractile effects of nucleotides in guinea pig isolated, perfused trachea: involvement of respiratory epithelium, prostanoids and Na+ and Cl- channels
J Pharmacol Exp Ther 1993 264: 210-216. [Abstract] [PDF]  

JS Fedan, JJ Belt, LX Yuan, and DG Frazer
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine
J Pharmacol Exp Ther 1993 264: 217-220. [Abstract] [PDF]  

EF Domino and J Sheng
N-methyl-D-aspartate receptor antagonist and dopamine D1 and D2 agonist interactions in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced hemiparkinsonian monkeys
J Pharmacol Exp Ther 1993 264: 221-225. [Abstract] [PDF]  

S Fujita, S Umeda, Y Funae, S Imaoka, H Abe, R Ishida, T Adachi, M Masuda, A Kazusaka, and T Suzuki
Regio- and stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver
J Pharmacol Exp Ther 1993 264: 226-233. [Abstract] [PDF]  

P Kostka, E Jang, EG Watson, JL Stewart, and EE Daniel
Nitric oxide synthase in the autonomic nervous system of canine ileum
J Pharmacol Exp Ther 1993 264: 234-239. [Abstract] [PDF]  

GW Gullikson, MA Virina, RF Loeffler, DC Yang, B Goldstin, SX Wang, C Moummi, DL Flynn, and DL Zabrowski
SC-49518 enhances gastric emptying of solid and liquid meals and stimulates gastrointestinal motility in dogs by a 5-hydroxytryptamine4 receptor mechanism
J Pharmacol Exp Ther 1993 264: 240-248. [Abstract] [PDF]  

ME Wolf, FJ White, R Nassar, RJ Brooderson, and MR Khansa
Differential development of autoreceptor subsensitivity and enhanced dopamine release during amphetamine sensitization
J Pharmacol Exp Ther 1993 264: 249-255. [Abstract] [PDF]  

JW Ferkany, GS Hamilton, RJ Patch, Z Huang, SA Borosky, DL Bednar, BE Jones, R Zubrowski, J Willetts, and EW Karbon
Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2- cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist
J Pharmacol Exp Ther 1993 264: 256-264. [Abstract] [PDF]  

MJ Winn, NK Asante, and DD Ku
Vasomotor responses of canine coronary arterial rings to NG-monomethyl- L-arginine and N omega nitro L-arginine methyl ester
J Pharmacol Exp Ther 1993 264: 265-270. [Abstract] [PDF]  

SW Watts and ML Cohen
Further evidence that the guinea pig tracheal contractile serotonergic receptor is a 5-hydroxytryptamine2 receptor: use of 5-methyltryptamine and dipropyl-5-carboxamidotryptamine
J Pharmacol Exp Ther 1993 264: 271-275. [Abstract] [PDF]  

NA Shahabi and BM Sharp
Activation of protein kinase C rapidly down-regulates naloxone- resistant receptors for beta-endorphin on U937 cells
J Pharmacol Exp Ther 1993 264: 276-281. [Abstract] [PDF]  

RA Gonzales, LC Roper, and SL Westbrook
Cholinergic modulation of N-methyl-D-aspartate-evoked [3H]norepinephrine release from rat cortical slices
J Pharmacol Exp Ther 1993 264: 282-288. [Abstract] [PDF]  

KD Youngren, DA Daly, and B Moghaddam
Distinct actions of endogenous excitatory amino acids on the outflow of dopamine in the nucleus accumbens
J Pharmacol Exp Ther 1993 264: 289-293. [Abstract] [PDF]  

CJ Heyser, RE Hampson, and SA Deadwyler
Effects of delta-9-tetrahydrocannabinol on delayed match to sample performance in rats: alterations in short-term memory associated with changes in task specific firing of hippocampal cells
J Pharmacol Exp Ther 1993 264: 294-307. [Abstract] [PDF]  

DJ Pettibone, BV Clineschmidt, MT Kishel, EV Lis, DR Reiss, CJ Woyden, BE Evans, RM Freidinger, DF Veber, and MJ Cook
Identification of an orally active, nonpeptidyl oxytocin antagonist
J Pharmacol Exp Ther 1993 264: 308-314. [Abstract] [PDF]  

JM Gallo, AR Swagler, M Mehta, and M Qian
Pharmacokinetic evaluation of drug interactions with anti-human immunodeficiency virus drugs. VI. Effect of the calcium channel blocker nimodipine on zidovudine kinetics in monkeys
J Pharmacol Exp Ther 1993 264: 315-320. [Abstract] [PDF]  

K Kaechi, Y Furukawa, R Ikegami, N Nakamura, F Omae, Y Hashimoto, K Hayashi, and S Furukawa
Pharmacological induction of physiologically active nerve growth factor in rat peripheral nervous system
J Pharmacol Exp Ther 1993 264: 321-326. [Abstract] [PDF]  

Y Takano and TL Yaksh
Chronic spinal infusion of dexmedetomidine, ST-91 and clonidine: spinal alpha 2 adrenoceptor subtypes and intrinsic activity
J Pharmacol Exp Ther 1993 264: 327-335. [Abstract] [PDF]  

P Hoffmann, I Heinroth-Hoffmann, and M Toraason
Alterations by a thromboxane A2 analog (U46619) of calcium dynamics in isolated rat cardiomyocytes
J Pharmacol Exp Ther 1993 264: 336-344. [Abstract] [PDF]  

P Nambi, M Pullen, M Jugus, and M Gellai
Rat kidney endothelin receptors in ischemia-induced acute renal failure
J Pharmacol Exp Ther 1993 264: 345-348. [Abstract] [PDF]  

B Nock, AL Giordano, BW Moore, and TJ Cicero
Properties of the putative epsilon opioid receptor: identification in rat, guinea pig, cow, pig and chicken brain
J Pharmacol Exp Ther 1993 264: 349-359. [Abstract] [PDF]  

WK Bickel, AH Oliveto, JB Kamien, ST Higgins, and JR Hughes
A novel-response procedure enhances the selectivity and sensitivity of a triazolam discrimination in humans
J Pharmacol Exp Ther 1993 264: 360-367. [Abstract] [PDF]  

JM Thomas and BB Hoffman
Buprenorphine prevents and reverses the expression of chronic etorphine- induced sensitization of adenylyl cyclase in SK-N-SH human neuroblastoma cells
J Pharmacol Exp Ther 1993 264: 368-374. [Abstract] [PDF]  

JJ Galligan
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by mu opioid and alpha-2 adrenergic agonists in guinea pig ileum
J Pharmacol Exp Ther 1993 264: 375-383. [Abstract] [PDF]  

DM Hammerbeck and DR Brown
Neurally mediated actions of leukotrienes on ion transport in guinea pig distal colon
J Pharmacol Exp Ther 1993 264: 384-390. [Abstract] [PDF]  

P Holzer, W Schluet, and CA Maggi
Ascending enteric reflex contraction: roles of acetylcholine and tachykinins in relation to distension and propagation of excitation
J Pharmacol Exp Ther 1993 264: 391-396. [Abstract] [PDF]  

T Hohlfeld, H Strobach, and K Schror
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury
J Pharmacol Exp Ther 1993 264: 397-405. [Abstract] [PDF]  

P Soares-da-Silva, MH Fernandes, and M Pestana
Studies on the role of sodium on the synthesis of dopamine in the rat kidney
J Pharmacol Exp Ther 1993 264: 406-414. [Abstract] [PDF]  

JK Zubieta and KA Frey
Autoradiographic mapping of M3 muscarinic receptors in the rat brain
J Pharmacol Exp Ther 1993 264: 415-422. [Abstract] [PDF]  

I Holopainen and WJ Wojcik
A specific antisense oligodeoxynucleotide to mRNAs encoding receptors with seven transmembrane spanning regions decreases muscarinic m2 and gamma-aminobutyric acidB receptors in rat cerebellar granule cells
J Pharmacol Exp Ther 1993 264: 423-430. [Abstract] [PDF]  

A Ricci, S Escaf, JA Vega, and F Amenta
Autoradiographic localization of dopamine D1 receptors in the human kidney
J Pharmacol Exp Ther 1993 264: 431-437. [Abstract] [PDF]  

TM Badger, MJ Ronis, CK Lumpkin, CR Valentine, M Shahare, D Irby, J Huang, C Mercado, P Thomas, and M Ingelman-Sundberg
Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat
J Pharmacol Exp Ther 1993 264: 438-447. [Abstract] [PDF]  

CR Breese, A D'Costa, RL Ingram, J Lenham, and WE Sonntag
Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth
J Pharmacol Exp Ther 1993 264: 448-456. [Abstract] [PDF]  

MD Maines, RD Mayer, JF Ewing, and WK Jr McCoubrey
Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein by ischemia/reperfusion: possible role of heme as both promotor of tissue damage and regulator of HSP32
J Pharmacol Exp Ther 1993 264: 457-462. [Abstract] [PDF]  

K Sunaga, DM Chuang, and R Ishitani
Tetrahydroaminoacridine is neurotrophic and promotes the expression of muscarinic receptor-coupled phosphoinositide turnover in differentiating cerebellar granule cells
J Pharmacol Exp Ther 1993 264: 463-468. [Abstract] [PDF]  

S Kamei, H Okada, Y Inoue, T Yoshioka, Y Ogawa, and H Toguchi
Antitumor effects of angiogenesis inhibitor TNP-470 in rabbits bearing VX-2 carcinoma by arterial administration of microspheres and oil solution
J Pharmacol Exp Ther 1993 264: 469-474. [Abstract] [PDF]  

C Jin, JO Miners, KJ Lillywhite, and PI Mackenzie
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs
J Pharmacol Exp Ther 1993 264: 475-479. [Abstract] [PDF]  

K Rasmussen, JF Czachura, ME Stockton, and JJ Howbert
Electrophysiological effects of diphenylpyrazolidinone cholecystokinin- B and cholecystokinin-A antagonists on midbrain dopamine neurons
J Pharmacol Exp Ther 1993 264: 480-488. [Abstract] [PDF]  

R Bals-Kubik, A Ableitner, A Herz, and TS Shippenberg
Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats
J Pharmacol Exp Ther 1993 264: 489-495. [Abstract] [PDF]  

J Nagakawa, K Hirota, I Hishinuma, K Miyamoto, J Sonoda, T Yamanaka, K Katayama, and I Yamatsu
Protective effect of E3330, a novel quinone derivative, in galactosamine-induced hepatitis in rats
J Pharmacol Exp Ther 1993 264: 496-500. [Abstract] [PDF]  

SP Roux, TB Tschopp, H Kuhn, B Steiner, and P Hadvary
Effects of heparin, aspirin and a synthetic platelet glycoprotein IIb- IIIa receptor antagonist (Ro 43-5054) on coronary artery reperfusion and reocclusion after thrombolysis with tissue-type plasminogen activator in the dog
J Pharmacol Exp Ther 1993 264: 501-508. [Abstract] [PDF]  

G Petersson, E Bacci, DM McDonald, and JA Nadel
Neurogenic plasma extravasation in the rat nasal mucosa is potentiated by peptidase inhibitors
J Pharmacol Exp Ther 1993 264: 509-514. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1993 264: 514. [Abstract] [PDF]  

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