ARTICLES:

Y Yamaguchi, FJ Fenoy, RJ Roman, and A Nasjletti

Angiotensin II influences the renal hemodynamic response to blockade of thromboxane A2 and prostaglandin H2 receptors
J Pharmacol Exp Ther 1992 263: 905-909. [Abstract] [PDF]  

EH Jr Gerstin, T Luong, and FJ Ehlert

Heparin, dextran and trypan blue allosterically modulate M2 muscarinic receptor binding properties and interfere with receptor-mediated inhibition of adenylate cyclase
J Pharmacol Exp Ther 1992 263: 910-917. [Abstract] [PDF]  

KJ Slavik and JE Szilagyi

Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors
J Pharmacol Exp Ther 1992 263: 918-927. [Abstract] [PDF]  

T Li, K Croce, and RJ Winquist

Vasoconstrictor and vasodilator effects of serotonin in the isolated rabbit kidney
J Pharmacol Exp Ther 1992 263: 928-932. [Abstract] [PDF]  

RM Burch, JR Connor, JM Bator, M Weitzberg, K Laemont, L Noronha-Blob, JP Sullivan, and LR Steranka

NPC 15669 inhibits the reversed passive Arthus reaction in rats by blocking neutrophil recruitment
J Pharmacol Exp Ther 1992 263: 933-937. [Abstract] [PDF]  

U Frei, R Schindler, C Matthies, and KM Koch

Glomerular hemodynamics of the clipped kidney: effects of captopril and diltiazem
J Pharmacol Exp Ther 1992 263: 938-942. [Abstract] [PDF]  

M Ohno, T Yamamoto, and S Watanabe

Effects of intrahippocampal injections of N-methyl-D-aspartate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task
J Pharmacol Exp Ther 1992 263: 943-950. [Abstract] [PDF]  

K Kuratani, M Yamazaki, H Kodama, and I Yamaguchi

Possible involvement of hyperinsulinemia and adrenergic activation in the pathogenesis of indomethacin-induced antral ulcers in nonfasted hamsters and refed rats
J Pharmacol Exp Ther 1992 263: 951-955. [Abstract] [PDF]  

Y Suzuki, Y Matsumura, Y Egi, and S Morimoto

Effects of Losartan, a nonpeptide angiotensin II receptor antagonist, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs
J Pharmacol Exp Ther 1992 263: 956-963. [Abstract] [PDF]  

R Kannan, JF Kuhlenkamp, M Ookhtens, and N Kaplowitz

Transport of glutathione at blood-brain barrier of the rat: inhibition by glutathione analogs and age-dependence
J Pharmacol Exp Ther 1992 263: 964-970. [Abstract] [PDF]  

T Fujita, M Nishikawa, C Tamaki, Y Takakura, M Hashida, and H Sezaki

Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives
J Pharmacol Exp Ther 1992 263: 971-978. [Abstract] [PDF]  

M Columbo, M Taglialatela, JA Warner, DW Jr MacGlashan, T Yasumoto, L Annunziato, and G Marone

Maitotoxin, a novel activator of mediator release from human basophils, induces large increases in cytosolic calcium resulting in histamine, but not leukotriene C4, release
J Pharmacol Exp Ther 1992 263: 979-986. [Abstract] [PDF]  

C Nebigil and KU Malik

Comparison of signal transduction mechanisms of alpha-2C and alpha-1A adrenergic receptor-stimulated prostaglandin synthesis
J Pharmacol Exp Ther 1992 263: 987-996. [Abstract] [PDF]  

RK Gordon, RR Gray, CB Reaves, DL Butler, and PK Chiang

Induced release of acetylcholine from guinea pig ileum longitudinal muscle-myenteric plexus by anatoxin-a
J Pharmacol Exp Ther 1992 263: 997-1002. [Abstract] [PDF]  

C Madhu, Z Gregus, and CD Klaassen

Marked interanimal differences in susceptibility of Sprague-Dawley rats to diquat-induced oxidative stress in the liver: correlation with hepatic uptake of diquat
J Pharmacol Exp Ther 1992 263: 1003-1008. [Abstract] [PDF]  

WT Jackson, RJ Boyd, LL Froelich, BE Mallett, and DM Gapinski

Specific inhibition of leukotriene B4-induced neutrophil activation by LY223982
J Pharmacol Exp Ther 1992 263: 1009-1014. [Abstract] [PDF]  

MD Swedberg, HE Shannon, B Nickel, and SR Goldberg

D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat
J Pharmacol Exp Ther 1992 263: 1015-1022. [Abstract] [PDF]  

MR Cernadas, A Lopez-Farre, A Riesco, MJ Gallego, G Espinosa, E Digiuni, L Hernando, S Casado, and C Caramelo

Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids
J Pharmacol Exp Ther 1992 263: 1023-1029. [Abstract] [PDF]  

RB Raffa, KD Wild, HI Mosberg, and F Porreca

Thermodynamic analysis of the temperature dependence of the dissociation constant of naloxone at opioid delta receptors in the mouse isolated vas deferens
J Pharmacol Exp Ther 1992 263: 1030-1035. [Abstract] [PDF]  

H Watanabe, S Ohdo, M Ishikawa, and N Ogawa

Effects of social isolation on pentobarbital activity in mice: relationship to racemate levels and enantiomer levels in brain
J Pharmacol Exp Ther 1992 263: 1036-1045. [Abstract] [PDF]  

C Correa-Sales, C Nacif-Coelho, K Reid, and M Maze

Inhibition of adenylate cyclase in the locus coeruleus mediates the hypnotic response to an alpha 2 agonist in the rat
J Pharmacol Exp Ther 1992 263: 1046-1049. [Abstract] [PDF]  

SE Ishikawa, K Okada, and T Saito

Modulation by intracellular calcium pool of arginine vasopressin- induced cellular cyclic AMP production in rat renal papillary collecting tubule cells in culture
J Pharmacol Exp Ther 1992 263: 1050-1055. [Abstract] [PDF]  

PJ Little, ML Adams, and TJ Cicero

Effects of alcohol on the hypothalamic-pituitary-gonadal axis in the developing male rat
J Pharmacol Exp Ther 1992 263: 1056-1061. [Abstract] [PDF]  

JE Porter, FJ Dowd, and PW Abel

Atypical alpha-1 adrenergic receptors on the rat parotid gland acinar cell
J Pharmacol Exp Ther 1992 263: 1062-1067. [Abstract] [PDF]  

TS Gaginella, MB Grisham, DB Thomas, R Walsh, and C Moummi

Oxidant-evoked release of acetylcholine from enteric neurons of the rat colon
J Pharmacol Exp Ther 1992 263: 1068-1073. [Abstract] [PDF]  

GJ Grover, PG Sleph, M Fox, and NC Trippodo

Role of endothelin-1 and big endothelin-1 in modulating coronary vascular tone, contractile function and severity of ischemia in rat hearts
J Pharmacol Exp Ther 1992 263: 1074-1082. [Abstract] [PDF]  

G Tavernier, J Galitzky, A Bousquet-Melou, JL Montastruc, and M Berlan

The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms
J Pharmacol Exp Ther 1992 263: 1083-1090. [Abstract] [PDF]  

CD la Rochelle, V Richard, JL Dubois-Rande, E Roupie, JF Giudicelli, L Hittinger, and A Berdeaux

Potassium channel openers dilate large epicardial coronary arteries in conscious dogs by an indirect, endothelium-dependent mechanism
J Pharmacol Exp Ther 1992 263: 1091-1096. [Abstract] [PDF]  

GE DeLander, HI Mosberg, and F Porreca

Involvement of adenosine in antinociception produced by spinal or supraspinal receptor-selective opioid agonists: dissociation from gastrointestinal effects in mice
J Pharmacol Exp Ther 1992 263: 1097-1104. [Abstract] [PDF]  

MZ Badr

Induction of peroxisomal enzyme activities by di-(2-ethylhexyl) phthalate in thyroidectomized rats with parathyroid replants
J Pharmacol Exp Ther 1992 263: 1105-1110. [Abstract] [PDF]  

JJ Andazola, JA Underwood, M Chiono, OA Torres, and CA Herman

Leukotriene B4 and leukotriene B5 have binding sites on lung membranes and cause contraction of bullfrog lung
J Pharmacol Exp Ther 1992 263: 1111-1117. [Abstract] [PDF]  

DR Compton, LH Gold, SJ Ward, RL Balster, and BR Martin

Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol
J Pharmacol Exp Ther 1992 263: 1118-1126. [Abstract] [PDF]  

H Ito, K Hidaka, K Miyata, T Kamato, A Nishida, and K Honda

Characterization of YM060, a potent and selective 5-hydroxytryptamine3 receptor antagonist, in rabbit nodose ganglion and N1E-115 neuroblastoma cells
J Pharmacol Exp Ther 1992 263: 1127-1132. [Abstract] [PDF]  

BT Gabelt and PL Kaufman

Inhibition of outflow facility and accommodative and miotic responses to pilocarpine in rhesus monkeys by muscarinic receptor subtype antagonists
J Pharmacol Exp Ther 1992 263: 1133-1139. [Abstract] [PDF]  

U Jaehde, MW Langemeijer, AG de Boer, and DD Breimer

Cerebrospinal fluid transport and disposition of the quinolones ciprofloxacin and pefloxacin in rats
J Pharmacol Exp Ther 1992 263: 1140-1146. [Abstract] [PDF]  

TA Pugsley, CL Christofferson, A Corbin, HA DeWald, S Demattos, LT Meltzer, SL Myers, YH Shih, SZ Whetzel, and JN Wiley

Pharmacological characterization of PD 118717, a putative piperazinyl benzopyranone dopamine autoreceptor agonist
J Pharmacol Exp Ther 1992 263: 1147-1158. [Abstract] [PDF]  

L Cook, SW Tam, and KW Rohrbach

DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects
J Pharmacol Exp Ther 1992 263: 1159-1166. [Abstract] [PDF]  

SW Tam, GF Steinfels, PJ Gilligan, WK Schmidt, and L Cook

DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles
J Pharmacol Exp Ther 1992 263: 1167-1174. [Abstract] [PDF]  

SG Culp, D Rominger, SW Tam, and EB De Souza

[3H]DuP 734 [1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'- oxoethyl)-piperidine HBr]: a receptor binding profile of a high- affinity novel sigma receptor ligand in guinea pig brain
J Pharmacol Exp Ther 1992 263: 1175-1187. [Abstract] [PDF]  

YX Wang and DP Brooks

The role of adenosine in glycine-induced glomerular hyperfiltration in rats
J Pharmacol Exp Ther 1992 263: 1188-1194. [Abstract] [PDF]  

TJ Torphy, HL Zhou, and LB Cieslinski

Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity
J Pharmacol Exp Ther 1992 263: 1195-1205. [Abstract] [PDF]  

JL Vatier, Z Gao, XM Fu-Cheng, MT Vitre, DA Levy, G Cohen, and M Mignon

Evidence for the interaction between antacid and gastric mucosa using an "artificial stomach" model including gastric mucosa
J Pharmacol Exp Ther 1992 263: 1206-1211. [Abstract] [PDF]  

FP Monnet, A Fournier, G Debonnel, and C de Montigny

Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor
J Pharmacol Exp Ther 1992 263: 1212-1218. [Abstract] [PDF]  

FP Monnet, G Debonnel, A Fournier, and C de Montigny

Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor
J Pharmacol Exp Ther 1992 263: 1219-1225. [Abstract] [PDF]  

A Claing, S Telemaque, A Cadieux, A Fournier, D Regoli, and P D'Orleans-Juste

Nonadrenergic and noncholinergic arterial dilatation and venoconstriction are mediated by calcitonin gene-related peptide1 and neurokinin-1 receptors, respectively, in the mesenteric vasculature of the rat after perivascular nerve stimulation
J Pharmacol Exp Ther 1992 263: 1226-1232. [Abstract] [PDF]  

OF Schanne and R Dumaine

Interaction of taurine with the fast Na-current in isolated rabbit myocytes
J Pharmacol Exp Ther 1992 263: 1233-1240. [Abstract] [PDF]  

A Giacometti, M Quartaroli, G Gaviraghi, D Micheli, and D Trist

Analysis of the interaction between lacidipine and BAY K 8644 in two isolated rabbit arteries
J Pharmacol Exp Ther 1992 263: 1241-1247. [Abstract] [PDF]  

J Kitanaka, H Hashimoto, M Gotoh, T Mayumi, and A Baba

Mechanism of extracellular ATP-stimulated phosphoinositide hydrolysis in rat glioma C6 cells
J Pharmacol Exp Ther 1992 263: 1248-1252. [Abstract] [PDF]  

A Veltmar, J Culman, F Qadri, W Rascher, and T Unger

Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release
J Pharmacol Exp Ther 1992 263: 1253-1260. [Abstract] [PDF]  

CF Toombs, NR Norman, VE Groppi, KS Lee, RC Gadwood, and RJ Shebuski

Limitation of myocardial injury with the potassium channel opener cromakalim and the nonvasoactive analog U-89,232: vascular vs. cardiac actions in vitro and in vivo
J Pharmacol Exp Ther 1992 263: 1261-1268. [Abstract] [PDF]  

RV Considine, JR Sherwin, and LL Simpson

Role of protein kinase C in short-term transmission at the mammalian neuromuscular junction
J Pharmacol Exp Ther 1992 263: 1269-1274. [Abstract] [PDF]  

CD Mahle, HL Wiener, FD Yocca, and S Maayani

Allosteric interactions between the binding sites of receptor agonists and guanine nucleotides: a comparative study of the 5- hydroxytryptamine1A and adenosine A1 receptor systems in rat hippocampal membranes
J Pharmacol Exp Ther 1992 263: 1275-1284. [Abstract] [PDF]  

C van Horne, BJ Hoffer, I Stromberg, and GA Gerhardt

Clearance and diffusion of locally applied dopamine in normal and 6- hydroxydopamine-lesioned rat striatum
J Pharmacol Exp Ther 1992 263: 1285-1292. [Abstract] [PDF]  

Y Takata, F Shimada, and H Kato

Differential effects of diazoxide, cromakalim and pinacidil on adrenergic neurotransmission and 86Rb+ efflux in rat brain cortical slices
J Pharmacol Exp Ther 1992 263: 1293-1301. [Abstract] [PDF]  

A Miyake, H Yamamoto, Y Takebayashi, H Imai, and K Honda

The novel natural product YM-26567-1 [(+)-trans-4-(3-dodecanoyl-2,4,6- trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman]: a competitive inhibitor of group II phospholipase A2
J Pharmacol Exp Ther 1992 263: 1302-1307. [Abstract] [PDF]  

SJ Weber, DL Greene, VJ Hruby, HI Yamamura, F Porreca, and TP Davis

Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration
J Pharmacol Exp Ther 1992 263: 1308-1316. [Abstract] [PDF]  

P Lazarovici and PI Lelkes

Pardaxin induces exocytosis in bovine adrenal medullary chromaffin cells independent of calcium
J Pharmacol Exp Ther 1992 263: 1317-1326. [Abstract] [PDF]  

I Angel, H Schoemaker, S Arbilla, AM Galzin, C Berry, R Niddam, C Pimoule, M Sevrin, A Wick, and SZ Langer

SL 84.0418: a novel, potent and selective alpha-2 adrenoceptor antagonist: in vitro pharmacological profile
J Pharmacol Exp Ther 1992 263: 1327-1333. [Abstract] [PDF]  

H Bergstrand, T Eriksson, A Hallberg, B Johansson, K Karabelas, P Michelsen, and A Nybom

Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase
J Pharmacol Exp Ther 1992 263: 1334-1346. [Abstract] [PDF]  

A Wada, Y Uezono, M Arita, T Yuhi, H Kobayashi, N Yanagihara, and F Izumi

Cooperative modulation of voltage-dependent sodium channels by brevetoxin and classical neurotoxins in cultured bovine adrenal medullary cells
J Pharmacol Exp Ther 1992 263: 1347-1351. [Abstract] [PDF]  

RH Schwinger, M Bohm, R Uhlmann, K La Rosee, A Koch, and E Erdmann

Increase of the extracellular magnesium concentration reduces cardiac glycoside toxicity in the human myocardium
J Pharmacol Exp Ther 1992 263: 1352-1359. [Abstract] [PDF]  

M Serra, MC Foddi, CA Ghiani, MA Melis, C Motzo, A Concas, E Sanna, and G Biggio

Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta- carboline derivative abecarnil
J Pharmacol Exp Ther 1992 263: 1360-1368. [Abstract] [PDF]  

JP Beregi, D Escande, N Coudray, P Mery, M Mestre, D Chemla, and Y Lecarpentier

Positive inotropic effects of RP 62719, a new pure class III antiarrhythmic agent, on guinea pig myocardium
J Pharmacol Exp Ther 1992 263: 1369-1376. [Abstract] [PDF]  

A Trifilieff, A Da Silva, Y Landry, and JP Gies

Effect of Hoe 140, a new B2 noncompetitive antagonist, on guinea pig tracheal bradykinin receptors
J Pharmacol Exp Ther 1992 263: 1377-1382. [Abstract] [PDF]  

BF Thomas, X Wei, and BR Martin

Characterization and autoradiographic localization of the cannabinoid binding site in rat brain using [3H]11-OH-delta 9-THC-DMH
J Pharmacol Exp Ther 1992 263: 1383-1390. [Abstract] [PDF]  

KA Frey and MM Howland

Quantitative autoradiography of muscarinic cholinergic receptor binding in the rat brain: distinction of receptor subtypes in antagonist competition assays
J Pharmacol Exp Ther 1992 263: 1391-1400. [Abstract] [PDF]  

BX Carlson, AM Mans, RA Hawkins, and HA Baghdoyan

Pentobarbital-enhanced [3H]flunitrazepam binding throughout the rat brain: an autoradiographic study
J Pharmacol Exp Ther 1992 263: 1401-1414. [Abstract] [PDF]  

NM Appel, JD Robbins, EB De Souza, and KB Seamon

[125I]-labeled forskolin analogs which discriminate adenylyl cyclase and a glucose transporter: pharmacological characterization and localization of binding sites in rat brain by in vitro receptor autoradiography
J Pharmacol Exp Ther 1992 263: 1415-1423. [Abstract] [PDF]  

CC Deck, TE Raya, MA Gaballa, and S Goldman

Baroreflex control of heart rate in rats with heart failure after myocardial infarction: effects of captopril
J Pharmacol Exp Ther 1992 263: 1424-1431. [Abstract] [PDF]  

MB Genter, J Llorens, JP O'Callaghan, DB Peele, KT Morgan, and KM Crofton

Olfactory toxicity of beta,beta'-iminodipropionitrile in the rat
J Pharmacol Exp Ther 1992 263: 1432-1439. [Abstract] [PDF]  

SD Skaper, L Facci, N Schiavo, G Vantini, F Moroni, R Dal Toso, and A Leon

Characterization of 2,4,5-trihydroxyphenylalanine neurotoxicity in vitro and protective effects of ganglioside GM1: implications for Parkinson's disease
J Pharmacol Exp Ther 1992 263: 1440-1446. [Abstract] [PDF]  

F Amenta, F Ferrante, A Rossodivita, and A Ricci

Pharmacological characterization and autoradiographic localization of dopamine receptors in human epicardial arteries
J Pharmacol Exp Ther 1992 263: 1447-1453. [Abstract] [PDF]  

PE Simson, KB Johnson, HA Jurevics, HE Criswell, TC Napier, GE Duncan, RA Mueller, and GR Breese

Augmented sensitivity of D1-dopamine receptors in lateral but not medial striatum after 6-hydroxydopamine-induced lesions in the neonatal rat
J Pharmacol Exp Ther 1992 263: 1454-1463. [Abstract] [PDF]  

SJ Kohlhepp, DN McGregor, SJ Cohen, ME Kohlhepp, and DN Gilbert

Determinants of the in vitro interaction of polyaspartic acid and aminoglycoside antibiotics
J Pharmacol Exp Ther 1992 263: 1464-1470. [Abstract] [PDF]  

X Boulenc, M Bourrie, I Fabre, C Roque, H Joyeux, Y Berger, and G Fabre

Regulation of cytochrome P450IA1 gene expression in a human intestinal cell line, Caco-2
J Pharmacol Exp Ther 1992 263: 1471-1478. [Abstract] [PDF]  

J Zhu, W Li, ML Toews, and TD Hexum

Neuropeptide Y inhibits forskolin-stimulated adenylate cyclase in bovine adrenal chromaffin cells via a pertussis toxin-sensitive process
J Pharmacol Exp Ther 1992 263: 1479-1486. [Abstract] [PDF]  

J Kukkonen, P Ojala, J Nasman, H Hamalainen, J Heikkila, and KE Akerman

Muscarinic receptor subtypes in human neuroblastoma cell lines SH-SY5Y and IMR-32 as determined by receptor binding, Ca++ mobilization and northern blotting
J Pharmacol Exp Ther 1992 263: 1487-1493. [Abstract] [PDF]  

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