ARTICLES:

T Takahashi, Y Tsunoda, Y Lu, J Wiley, and C Owyang

Nicotinic receptor-evoked release of acetylcholine and somatostatin in the myenteric plexus is coupled to calcium influx via N-type calcium channels
J Pharmacol Exp Ther 1992 263: 1-5. [Abstract] [PDF]  

D de Cheffoy de Courcelles, K de Loore, E Freyne, and PA Janssen

Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds
J Pharmacol Exp Ther 1992 263: 6-14. [Abstract] [PDF]  

JA Leedham, JQ Kong, DA Taylor, SM Johnson, and WW Fleming

Membrane potential in myenteric neurons associated with tolerance and dependence to morphine
J Pharmacol Exp Ther 1992 263: 15-19. [Abstract] [PDF]  

AN Schoffelmeer, TJ De Vries, F Hogenboom, VJ Hruby, PS Portoghese, and AH Mulder

Opioid receptor antagonists discriminate between presynaptic mu and delta receptors and the adenylate cyclase-coupled opioid receptor complex in the brain
J Pharmacol Exp Ther 1992 263: 20-24. [Abstract] [PDF]  

A Yamamoto, E Hayakawa, Y Kato, A Nishiura, and VH Lee

A mechanistic study on enhancement of rectal permeability to insulin in the albino rabbit
J Pharmacol Exp Ther 1992 263: 25-31. [Abstract] [PDF]  

T van der Hoeven, R Lefevre, and R Mankes

Effects of intrauterine position on the hepatic microsomal polysubstrate monooxygenase and cytosolic glutathione S-transferase activity, plasma sex steroids and relative organ weights in adult male and female Long-Evans rats
J Pharmacol Exp Ther 1992 263: 32-39. [Abstract] [PDF]  

ZH Zhang, CH Follmer, JS Sarma, F Chen, and BN Singh

Effect of ambasilide, a new class III agent, on plateau currents in isolated guinea pig ventricular myocytes: block of delayed outward potassium current
J Pharmacol Exp Ther 1992 263: 40-48. [Abstract] [PDF]  

JJ Choi, GJ Huang, E Shafik, WH Wu, and JJ McArdle

Imipramine's selective suppression of an L-type calcium channel in neurons of murine dorsal root ganglia involves G proteins
J Pharmacol Exp Ther 1992 263: 49-53. [Abstract] [PDF]  

SJ Henderson and WE Lindup

Renal organic acid transport: uptake by rat kidney slices of a furan dicarboxylic acid which inhibits plasma protein binding of acidic ligands in uremia
J Pharmacol Exp Ther 1992 263: 54-60. [Abstract] [PDF]  

P Blandina, D Johnson, J Walcott, and J Goldfarb

Release of endogenous norepinephrine from rat hypothalamus by stimulation of N-methyl-D-aspartic acid receptors
J Pharmacol Exp Ther 1992 263: 61-68. [Abstract] [PDF]  

D Fau, A Berson, D Eugene, B Fromenty, C Fisch, and D Pessayre

Mechanism for the hepatotoxicity of the antiandrogen, nilutamide. Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes
J Pharmacol Exp Ther 1992 263: 69-77. [Abstract] [PDF]  

ME Berger, MS Golub, CT Chang, JA al-Kharouf, MD Nyby, M Hori, AS Brickman, and ML Tuck

Flavonoid potentiation of contractile responses in rat blood vessels
J Pharmacol Exp Ther 1992 263: 78-83. [Abstract] [PDF]  

MK James, A Vuong, MK Grizzle, SV Schuster, and JE Shaffer

Hemodynamic effects of GI 87084B, an ultra-short acting mu-opioid analgesic, in anesthetized dogs
J Pharmacol Exp Ther 1992 263: 84-91. [Abstract] [PDF]  

TL Yue, HY Cheng, PG Lysko, PJ McKenna, R Feuerstein, JL Gu, KA Lysko, LL Davis, and G Feuerstein

Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger
J Pharmacol Exp Ther 1992 263: 92-98. [Abstract] [PDF]  

DE Selley and JM Bidlack

Effects of beta-endorphin on mu and delta opioid receptor-coupled G- protein activity: low-Km GTPase studies
J Pharmacol Exp Ther 1992 263: 99-104. [Abstract] [PDF]  

JH Lin, IW Chen, and J King

Dose-dependent toxicokinetics of L-689,502, a potent human immunodeficiency virus protease inhibitor, in rats and dogs
J Pharmacol Exp Ther 1992 263: 105-111. [Abstract] [PDF]  

T Godfraind, C Dessy, and S Salomone

A comparison of the potency of selective L-calcium channel blockers in human coronary and internal mammary arteries exposed to serotonin
J Pharmacol Exp Ther 1992 263: 112-122. [Abstract] [PDF]  

DJ Cushing and ML Cohen

Serotonin-induced relaxation in canine coronary artery smooth muscle
J Pharmacol Exp Ther 1992 263: 123-129. [Abstract] [PDF]  

RE Howell and PN Lanken

Pulmonary accumulation of propranolol in vivo: sites and physiochemical mechanism
J Pharmacol Exp Ther 1992 263: 130-135. [Abstract] [PDF]  

AB Malmberg and TL Yaksh

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat
J Pharmacol Exp Ther 1992 263: 136-146. [Abstract] [PDF]  

F Porreca, AE Takemori, M Sultana, PS Portoghese, WD Bowen, and HI Mosberg

Modulation of mu-mediated antinociception in the mouse involves opioid delta-2 receptors
J Pharmacol Exp Ther 1992 263: 147-152. [Abstract] [PDF]  

B Tesfamariam, ML Brown, and RA Cohen

Aldose reductase and myo-inositol in endothelial cell dysfunction caused by elevated glucose
J Pharmacol Exp Ther 1992 263: 153-157. [Abstract] [PDF]  

AF Hajj-Ali and BG Zimmerman

Enhanced blood pressure and renal hemodynamic effect of chronic versus acute lisinopril administration in the rabbit
J Pharmacol Exp Ther 1992 263: 158-162. [Abstract] [PDF]  

GD Pennock, TE Raya, JJ Bahl, S Goldman, and E Morkin

Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity
J Pharmacol Exp Ther 1992 263: 163-169. [Abstract] [PDF]  

N Marczin, US Ryan, and JD Catravas

Methylene blue inhibits nitrovasodilator- and endothelium-derived relaxing factor-induced cyclic GMP accumulation in cultured pulmonary arterial smooth muscle cells via generation of superoxide anion
J Pharmacol Exp Ther 1992 263: 170-179. [Abstract] [PDF]  

BK Yamamoto and HY Meltzer

The effect of the atypical antipsychotic drug, amperozide, on carrier- mediated striatal dopamine release measured in vivo
J Pharmacol Exp Ther 1992 263: 180-185. [Abstract] [PDF]  

JS Strobl and VA Peterson

Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13
J Pharmacol Exp Ther 1992 263: 186-193. [Abstract] [PDF]  

M Iguchi, T Nakajima, T Hisada, T Sugimoto, and Y Kurachi

On the mechanism of papaverine inhibition of the voltage-dependent Ca++ current in isolated smooth muscle cells from the guinea pig trachea
J Pharmacol Exp Ther 1992 263: 194-200. [Abstract] [PDF]  

H Yazawa, M Takanashi, K Sudoh, O Inagaki, and K Honda

Characterization of [3H]YM617, R-(-)-5-[2-[[2[ethoxyring(n)-3H](o- ethoxyphenoxy)ethyl]amino]- propyl]-2-methoxybenzenesulfonamide HCl, a potent and selective alpha-1 adrenoceptor radioligand
J Pharmacol Exp Ther 1992 263: 201-206. [Abstract] [PDF]  

Y Zhu, HK Im, and WB Im

Block of voltage-gated potassium currents by anticonvulsant U-54494A in mouse neuroblastoma cells
J Pharmacol Exp Ther 1992 263: 207-213. [Abstract] [PDF]  

F Hata, A Fujita, K Saeki, I Kishi, T Takeuchi, and O Yagasaki

Selective inhibitory effects of calcium channel antagonists on the two components of the neurogenic response of guinea pig vas deferens
J Pharmacol Exp Ther 1992 263: 214-220. [Abstract] [PDF]  

MT Griffin and FJ Ehlert

Specific inhibition of isoproterenol-stimulated cyclic AMP accumulation by M2 muscarinic receptors in rat intestinal smooth muscle
J Pharmacol Exp Ther 1992 263: 221-225. [Abstract] [PDF]  

P Kostka, S Ahmad, CY Kwan, EE Daniel, RK Gordon, and PK Chiang

Prejunctional muscarinic receptors in the deep muscular plexus of canine ileum: comparison with smooth muscle receptors
J Pharmacol Exp Ther 1992 263: 226-231. [Abstract] [PDF]  

NC De Fiebre, RJ Marley, JM Wehner, and AC Collins

Lipid solubility of sedative-hypnotic drugs influences hypothermic and hypnotic responses of long-sleep and short-sleep mice
J Pharmacol Exp Ther 1992 263: 232-240. [Abstract] [PDF]  

S Oda, T Sano, Y Morishita, and Y Matsuda

Pharmacological profile of HS-142-1, a novel nonpeptide atrial natriuretic peptide (ANP) antagonist of microbial origin. II. Restoration by HS-142-1 of ANP-induced inhibition of aldosterone production in adrenal glomerulosa cells
J Pharmacol Exp Ther 1992 263: 241-245. [Abstract] [PDF]  

JY Xu, JM Fujimoto, and LF Tseng

Involvement of supraspinal epsilon and mu opioid receptors in inhibition of the tail-flick response induced by etorphine in the mouse
J Pharmacol Exp Ther 1992 263: 246-252. [Abstract] [PDF]  

MF Jarvis, GW Gessner, GE Martin, M Jaye, MW Ravera, and CA Dionne

Characterization of [125I]acidic fibroblast growth factor binding to the cloned human fibroblast growth factor receptor, FGF-flg, on NIH 3T3 cell membranes: inhibitory effects of heparin, pertussis toxin and guanine nucleotides
J Pharmacol Exp Ther 1992 263: 253-263. [Abstract] [PDF]  

AB Malmberg and TL Yaksh

Isobolographic and dose-response analyses of the interaction between intrathecal mu and delta agonists: effects of naltrindole and its benzofuran analog (NTB)
J Pharmacol Exp Ther 1992 263: 264-275. [Abstract] [PDF]  

EM Hoenicke, SA Vanecek, and JH Woods

The discriminative stimulus effects of clozapine in pigeons: involvement of 5-hydroxytryptamine1C and 5-hydroxytryptamine2 receptors
J Pharmacol Exp Ther 1992 263: 276-284. [Abstract] [PDF]  

SW Kerr, LV Buchanan, S Bunting, and WR Mathews

Evidence that S-nitrosothiols are responsible for the smooth muscle relaxing activity of the bovine retractor penis inhibitory factor
J Pharmacol Exp Ther 1992 263: 285-292. [Abstract] [PDF]  

HO Garland, DJ Phipps, and ES Harpur

Gentamicin-induced hypercalciuria in the rat: assessment of nephron site involved
J Pharmacol Exp Ther 1992 263: 293-297. [Abstract] [PDF]  

G Perrault, E Morel, DJ Sanger, and B Zivkovic

Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem
J Pharmacol Exp Ther 1992 263: 298-303. [Abstract] [PDF]  

M Garbarg, JM Arrang, A Rouleau, X Ligneau, MD Tuong, JC Schwartz, and CR Ganellin

S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist
J Pharmacol Exp Ther 1992 263: 304-310. [Abstract] [PDF]  

TW Moody, J Staley, F Zia, DH Coy, and RT Jensen

Neuromedin B binds with high affinity, elevates cytosolic calcium and stimulates the growth of small-cell lung cancer cell lines
J Pharmacol Exp Ther 1992 263: 311-317. [Abstract] [PDF]  

CW Callaway and MA Geyer

Tolerance and cross-tolerance to the activating effects of 3,4- methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist
J Pharmacol Exp Ther 1992 263: 318-326. [Abstract] [PDF]  

A Pittaluga and M Raiteri

N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. III. Changes in the NMDA receptor complex induced by their functional cooperation
J Pharmacol Exp Ther 1992 263: 327-333. [Abstract] [PDF]  

Z Hu and PG Wells

In vitro and in vivo biotransformation and covalent binding of benzo(a)pyrene in Gunn and RHA rats with a genetic deficiency in bilirubin uridine diphosphate-glucuronosyltransferase
J Pharmacol Exp Ther 1992 263: 334-342. [Abstract] [PDF]  

RV Bhat, AJ Cole, and JM Baraban

Chronic cocaine treatment suppresses basal expression of zif268 in rat forebrain: in situ hybridization studies
J Pharmacol Exp Ther 1992 263: 343-349. [Abstract] [PDF]  

SG Beck, KC Choi, and TJ List

Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells
J Pharmacol Exp Ther 1992 263: 350-359. [Abstract] [PDF]  

JS Leeder, RJ Riley, VA Cook, and SP Spielberg

Human anti-cytochrome P450 antibodies in aromatic anticonvulsant- induced hypersensitivity reactions
J Pharmacol Exp Ther 1992 263: 360-367. [Abstract] [PDF]  

XZ Ding and I Mocchetti

Regulation of cholecystokinin mRNA content in rat striatum: a glutamatergic hypothesis
J Pharmacol Exp Ther 1992 263: 368-373. [Abstract] [PDF]  

ML Ogletree, EH O'Keefe, SK Durham, B Rubin, and G Aberg

Gastroprotective effects of thromboxane receptor antagonists
J Pharmacol Exp Ther 1992 263: 374-380. [Abstract] [PDF]  

H Sakai, T Okamoto, and Y Kikkawa

Suppression of hepatic drug metabolism by the interferon inducer, polyriboinosinic acid:polyribocitidylic acid
J Pharmacol Exp Ther 1992 263: 381-386. [Abstract] [PDF]  

SD Ray, CL Sorge, LM Kamendulis, and GB Corcoran

Ca(++)-activated DNA fragmentation and dimethylnitrosamine-induced hepatic necrosis: effects of Ca(++)-endonuclease and poly(ADP-ribose) polymerase inhibitors in mice
J Pharmacol Exp Ther 1992 263: 387-394. [Abstract] [PDF]  

IM Lang and SK Sarna

The role of adrenergic receptors in the initiation of vomiting and its gastrointestinal motor correlates
J Pharmacol Exp Ther 1992 263: 395-403. [Abstract] [PDF]  

CR Albrightson, P Nambi, B Zabko-Potapovich, G Dytko, and T Groom

Effect of thrombin on proliferation, contraction and prostaglandin production of rat glomerular mesangial cells in culture
J Pharmacol Exp Ther 1992 263: 404-412. [Abstract] [PDF]  

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