ARTICLES:

MJ Millan, JM Rivet, H Canton, F Lejeune, K Bervoets, M Brocco, A Gobert, B Lefebvre de Ladonchamps, S Le Marouille-Girardon, and L Verriele

S 14671: a naphtylpiperazine 5-hydroxytryptamine1A agonist of exceptional potency and high efficacy possessing antagonist activity at 5-hydroxytryptamine1C/2 receptors
J Pharmacol Exp Ther 1992 262: 451-463. [Abstract] [PDF]  

Y Itzhak and I Stein

Sensitization to the toxic effects of cocaine in mice is associated with the regulation of N-methyl-D-aspartate receptors in the cortex
J Pharmacol Exp Ther 1992 262: 464-470. [Abstract] [PDF]  

ML Toews, JM Hoffman, SA Liewer, and LJ Arneson-Rotert

Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells
J Pharmacol Exp Ther 1992 262: 471-478. [Abstract] [PDF]  

LH Gold, RL Balster, RL Barrett, DT Britt, and BR Martin

A comparison of the discriminative stimulus properties of delta 9- tetrahydrocannabinol and CP 55,940 in rats and rhesus monkeys
J Pharmacol Exp Ther 1992 262: 479-486. [Abstract] [PDF]  

JE Dildy-Mayfield and RA Harris

Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino- 3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes
J Pharmacol Exp Ther 1992 262: 487-494. [Abstract] [PDF]  

M Schwanstecher, S Behrends, C Brandt, and U Panten

The binding properties of the solubilized sulfonylurea receptor from a pancreatic B-cell line are modulated by the Mg(++)-complex of ATP
J Pharmacol Exp Ther 1992 262: 495-502. [Abstract] [PDF]  

RP Koopmans, MC Braat, B Oosterhuis, and CJ van Boxtel

Time-dependent effects of dexamethasone administration on the suppression of plasma hydrocortisone, assessed with a pharmacokinetic model
J Pharmacol Exp Ther 1992 262: 503-508. [Abstract] [PDF]  

MC Braat, B Oosterhuis, RP Koopmans, JM Meewis, and CJ Van Boxtel

Kinetic-dynamic modeling of lymphocytopenia induced by the combined action of dexamethasone and hydrocortisone in humans, after inhalation and intravenous administration of dexamethasone
J Pharmacol Exp Ther 1992 262: 509-515. [Abstract] [PDF]  

D Chemla, E Scalbert, P Desche, JC Pourny, F Lambert, and Y Lecarpentier

Effects of perindopril on myocardial inotropy, lusitropy and economy, and on diaphragmatic contractility in the cardiomyopathic Syrian hamster
J Pharmacol Exp Ther 1992 262: 516-525. [Abstract] [PDF]  

Q Jiang, A Seyed-Mozaffari, S Archer, and JM Bidlack

Antinociceptive properties of two alkylating derivatives of morphinone: 14 beta-(thioglycolamido)-7,8-dihydromorphinone (TAMO) and 14 beta- (bromoacetamido)-7,8-dihydromorphinone (H2BAMO)
J Pharmacol Exp Ther 1992 262: 526-531. [Abstract] [PDF]  

NM Deighton, S Motomura, S Bals, HR Zerkowski, and OE Brodde

Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, dopamine, dobutamine, denopamine and xamoterol in isolated human right atrium
J Pharmacol Exp Ther 1992 262: 532-538. [Abstract] [PDF]  

K Williams, LM Pullan, C Romano, RJ Powel, AI Salama, and PB Molinoff

An antagonist/partial agonist at the polyamine recognition site of the N-methyl-D-aspartate receptor that alters the properties of the glutamate recognition site
J Pharmacol Exp Ther 1992 262: 539-544. [Abstract] [PDF]  

NA Moore, NC Tye, MS Axton, and FC Risius

The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent
J Pharmacol Exp Ther 1992 262: 545-551. [Abstract] [PDF]  

I Van Liefde, A Van Witzenburg, and G Vauquelin

Multiple beta adrenergic receptor subclasses mediate the l- isoproterenol-induced lipolytic response in rat adipocytes
J Pharmacol Exp Ther 1992 262: 552-558. [Abstract] [PDF]  

BF Ramos, Y Zhang, V Angkachatchai, and BA Jakschik

Mast cell mediators regulate vascular permeability changes in Arthus reaction
J Pharmacol Exp Ther 1992 262: 559-565. [Abstract] [PDF]  

BE Wood, SE O'Connor, and P Leff

Adenosine 5'-(2-fluorodiphosphate) is not a selective P2Y purinoceptor agonist in the rabbit jugular vein
J Pharmacol Exp Ther 1992 262: 566-569. [Abstract] [PDF]  

H Ninomiya, Y Uchida, M Saotome, A Nomura, H Ohse, H Matsumoto, F Hirata, and S Hasegawa

Endothelins constrict guinea pig tracheas by multiple mechanisms
J Pharmacol Exp Ther 1992 262: 570-576. [Abstract] [PDF]  

M Narita, Y Furukawa, M Murakami, M Takei, LM Ren, and S Chiba

Parasympatholytic effects of vecuronium are mediated by nicotinic and muscarinic receptors in hearts of anesthetized dogs
J Pharmacol Exp Ther 1992 262: 577-583. [Abstract] [PDF]  

SJ Wall, RP Yasuda, M Li, W Ciesla, and BB Wolfe

Differential regulation of subtypes m1-m5 of muscarinic receptors in forebrain by chronic atropine administration
J Pharmacol Exp Ther 1992 262: 584-588. [Abstract] [PDF]  

S Yamada, Y Matsuoka, Y Kato, R Kimura, and O Inagaki

A sustained occupancy in vivo of cardiovascular calcium antagonist receptors by mepirodipine and its relation to pharmacodynamic effect in spontaneously hypertensive rats
J Pharmacol Exp Ther 1992 262: 589-594. [Abstract] [PDF]  

EH Ohlstein, M Gellai, DP Brooks, L Vickery, J Jugus, A Sulpizio, RR Jr Ruffolo, J Weinstock, and RM Edwards

The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism
J Pharmacol Exp Ther 1992 262: 595-601. [Abstract] [PDF]  

SR Tella, CW Schindler, and SR Goldberg

Cardiovascular effects of cocaine in conscious rats: relative significance of central sympathetic stimulation and peripheral neuronal monoamine uptake and release mechanisms
J Pharmacol Exp Ther 1992 262: 602-610. [Abstract] [PDF]  

CL Cioffi, RF Jr Neale, RH Jackson, and MA Sills

Characterization of rat lung endothelin receptor subtypes which are coupled to phosphoinositide hydrolysis
J Pharmacol Exp Ther 1992 262: 611-618. [Abstract] [PDF]  

WJ Dutczak and N Ballatori

gamma-Glutamyltransferase-dependent biliary-hepatic recycling of methyl mercury in the guinea pig
J Pharmacol Exp Ther 1992 262: 619-623. [Abstract] [PDF]  

AC Petropoulos, SL Winbery, and LA Barker

Effect of short-term treatment with gastrin and related peptides on gastrointestinal histamine H2-receptors
J Pharmacol Exp Ther 1992 262: 624-631. [Abstract] [PDF]  

M Naka, DE Mais, TA Morinelli, N Hamanaka, JE Jr Oatis, and PV Halushka

7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors
J Pharmacol Exp Ther 1992 262: 632-637. [Abstract] [PDF]  

DN Jones and SG Holtzman

Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors
J Pharmacol Exp Ther 1992 262: 638-645. [Abstract] [PDF]  

JL Ellis and BJ Undem

Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea
J Pharmacol Exp Ther 1992 262: 646-653. [Abstract] [PDF]  

WF Hood, NM Gray, MS Dappen, GB Watson, RP Compton, AA Cordi, TH Lanthorn, and JB Monahan

Characterization of indole-2-carboxylate derivatives as antagonists of N-methyl-D-aspartate receptor activity at the associated glycine recognition site
J Pharmacol Exp Ther 1992 262: 654-660. [Abstract] [PDF]  

IN Pessah, FC Mohr, M Schiedt, and RM Joy

Stereoselective modulation of ryanodine-sensitive calcium channels by the delta isomer of hexachlorocyclohexane (delta-HCH)
J Pharmacol Exp Ther 1992 262: 661-669. [Abstract] [PDF]  

YQ Xu, AS Pickoff, and CW Clarkson

Developmental changes in the effects of lidocaine on sodium channels in rat cardiac myocytes
J Pharmacol Exp Ther 1992 262: 670-676. [Abstract] [PDF]  

PP Bertrand and JJ Galligan

Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine
J Pharmacol Exp Ther 1992 262: 677-682. [Abstract] [PDF]  

K Yeleswaram, DW Rurak, C Hall, MR Wright, and JE Axelson

Pharmacokinetics and pharmacodynamics of labetalol in the pregnant sheep
J Pharmacol Exp Ther 1992 262: 683-691. [Abstract] [PDF]  

NA Darmani, BR Martin, and RA Glennon

Behavioral evidence for differential adaptation of the serotonergic system after acute and chronic treatment with (+/- )-1-(2,5-dimethoxy-4- iodophenyl)-2-aminopropane (DOI) or ketanserin
J Pharmacol Exp Ther 1992 262: 692-698. [Abstract] [PDF]  

CR Bowden, SJ Voina, R Woestenborghs, R De Coster, and J Heykants

Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro
J Pharmacol Exp Ther 1992 262: 699-706. [Abstract] [PDF]  

KL Preston, B Wolf, JJ Guarino, and RR Griffiths

Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability
J Pharmacol Exp Ther 1992 262: 707-720. [Abstract] [PDF]  

SR Smith, AW Watnick, RW Bryant, M Billah, and MI Siegel

Actions of a 5-lipoxygenase inhibitor, Sch 40120, on acute inflammatory responses
J Pharmacol Exp Ther 1992 262: 721-728. [Abstract] [PDF]  

G Wiemer and K Wirth

Production of cyclic GMP via activation of B1 and B2 kinin receptors in cultured bovine aortic endothelial cells
J Pharmacol Exp Ther 1992 262: 729-733. [Abstract] [PDF]  

RT McCabe, AH Newman, and P Skolnick

AHN 683: a fluorescent ligand for peripheral-type benzodiazepine receptors
J Pharmacol Exp Ther 1992 262: 734-740. [Abstract] [PDF]  

JS Fedan and DG Frazer

Influence of epithelium on the reactivity of guinea pig isolated, perfused trachea to bronchoactive drugs
J Pharmacol Exp Ther 1992 262: 741-750. [Abstract] [PDF]  

SL Pugh, MS Boone, and MW Emmett-Oglesby

Tolerance, cross-tolerance and withdrawal in rats made dependent on diazepam
J Pharmacol Exp Ther 1992 262: 751-758. [Abstract] [PDF]  

M Rinaldi-Carmona, C Congy, V Santucci, J Simiand, B Gautret, G Neliat, B Labeeuw, G Le Fur, P Soubrie, and JC Breliere

Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonist
J Pharmacol Exp Ther 1992 262: 759-768. [Abstract] [PDF]  

R Invernizzi, L Pozzi, F Vallebuona, I Bonini, G Sacchetti, and R Samanin

Effect of amineptine on regional extracellular concentrations of dopamine and noradrenaline in the rat brain
J Pharmacol Exp Ther 1992 262: 769-774. [Abstract] [PDF]  

G Jagadeesh and RC Deth

Phorbol ester and staurosporine modulation of antagonist and agonist binding to alpha-2 adrenergic receptors: differential influence on Na+ versus guanylylnucleotide regulation
J Pharmacol Exp Ther 1992 262: 775-783. [Abstract] [PDF]  

GP Dube, DE Mais, JA Jakubowski, KA Brune, BG Utterback, TA True, LE Rinkema, and WL Kurtz

In vitro characterization of a novel TXA2/PGH2 receptor ligand (S-145) in platelets and vascular and airway smooth muscle
J Pharmacol Exp Ther 1992 262: 784-791. [Abstract] [PDF]  

MG Corda, M Orlandi, D Lecca, and O Giorgi

Decrease in GABAergic function induced by pentylenetetrazol kindling in rats: antagonism by MK-801
J Pharmacol Exp Ther 1992 262: 792-800. [Abstract] [PDF]  

DW Sapp, U Witte, DM Turner, B Longoni, N Kokka, and RW Olsen

Regional variation in steroid anesthetic modulation of [35S]TBPS binding to gamma-aminobutyric acidA receptors in rat brain
J Pharmacol Exp Ther 1992 262: 801-808. [Abstract] [PDF]  

E Carmeliet

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide
J Pharmacol Exp Ther 1992 262: 809-817. [Abstract] [PDF]  

V Mares, M Baudysova, J Kvitek, V Hnatovicz, J Cervena, J Vacik, and J Folbergrova

Accumulation of boron-10 (10B) in cell cultures exposed to mercaptododecaborate (Na2H(11)10B12SH) used for the neutron capture therapy of brain tumors
J Pharmacol Exp Ther 1992 262: 818-822. [Abstract] [PDF]  

DL Somers and RM Beckstead

N-methyl-D-aspartate receptor antagonism alters substance P and met5- enkephalin biosynthesis in neurons of the rat striatum
J Pharmacol Exp Ther 1992 262: 823-833. [Abstract] [PDF]  

T Whittem, RG Schnellmann, and DC Ferguson

Poly-L-aspartic acid does but triiodothyronine does not protect against gentamicin-induced cytotoxicity in the porcine kidney cell line LLC-PK1
J Pharmacol Exp Ther 1992 262: 834-840. [Abstract] [PDF]  

M Kimura, K Maeda, Y Harasawa, Y Ohno, M Nakamura, I Sakurai, and S Hayashi

Recovery of endothelium-dependent responses by reseeding endothelial cells in culture onto the denuded coronary artery
J Pharmacol Exp Ther 1992 262: 841-849. [Abstract] [PDF]  

E Montcalm-Mazzilli and T Shea-Donohue

Effect of leukotriene D4 on gastric emptying and secretion in rhesus monkeys
J Pharmacol Exp Ther 1992 262: 850-854. [Abstract] [PDF]  

KB Johnson, HE Criswell, KF Jensen, PE Simson, RA Mueller, and GR Breese

Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity
J Pharmacol Exp Ther 1992 262: 855-865. [Abstract] [PDF]  

PB Jacobson and RS Jacobs

Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part I: Physiological and biochemical studies in murine inflammatory models
J Pharmacol Exp Ther 1992 262: 866-873. [Abstract] [PDF]  

PB Jacobson and RS Jacobs

Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part II: Biochemical studies in the human neutrophil
J Pharmacol Exp Ther 1992 262: 874-882. [Abstract] [PDF]  

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