ARTICLES:

YD Sun and CG Benishin

Effects of calcitonin gene-related peptide on longitudinal muscle and myenteric plexus of guinea pig ileum
J Pharmacol Exp Ther 1991 259: 947-952. [Abstract] [PDF]  

H Echizen, H Takahashi, H Nakamura, K Ochiai, K Chiba, K Koike, H Ogata, and T Ishizaki

Stereoselective disposition and metabolism of disopyramide in pediatric patients
J Pharmacol Exp Ther 1991 259: 953-960. [Abstract] [PDF]  

JA Auchampach, M Maruyama, I Cavero, and GJ Gross

The new K+ channel opener Aprikalim (RP 52891) reduces experimental infarct size in dogs in the absence of hemodynamic changes
J Pharmacol Exp Ther 1991 259: 961-967. [Abstract] [PDF]  

T Ingi, Y Kitajima, Y Minamitake, and S Nakanishi

Characterization of ligand-binding properties and selectivities of three rat tachykinin receptors by transfection and functional expression of their cloned cDNAs in mammalian cells
J Pharmacol Exp Ther 1991 259: 968-975. [Abstract] [PDF]  

HE Nye, FJ Seidler, and TA Slotkin

Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs
J Pharmacol Exp Ther 1991 259: 976-981. [Abstract] [PDF]  

D Rampe and AE Lacerda

A new site for the activation of cardiac calcium channels defined by the nondihydropyridine FPL 64176
J Pharmacol Exp Ther 1991 259: 982-987. [Abstract] [PDF]  

WA Banks, L Ortiz, SR Plotkin, and AJ Kastin

Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism
J Pharmacol Exp Ther 1991 259: 988-996. [Abstract] [PDF]  

G Drapeau, D deBlois, and F Marceau

Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins
J Pharmacol Exp Ther 1991 259: 997-1003. [Abstract] [PDF]  

WE Perkins, EG Burton, BS Tsai, PW Collins, JJ Casler, AF Gasiecki, RF Bauer, PH Jones, and TS Gaginella

SC-46275: a potent, long-acting gastric antisecretory prostaglandin with low oral bioavailability in the dog
J Pharmacol Exp Ther 1991 259: 1004-1007. [Abstract] [PDF]  

EM Gould, CR Craig, WW Fleming, and DA Taylor

Sensitivity of cerebellar Purkinje neurons to neurotransmitters in genetically epileptic rats
J Pharmacol Exp Ther 1991 259: 1008-1012. [Abstract] [PDF]  

MI Sweeney, TD White, and J Sawynok

Intracerebroventricular morphine releases adenosine and adenosine 3',5'- cyclic monophosphate from the spinal cord via a serotonergic mechanism
J Pharmacol Exp Ther 1991 259: 1013-1018. [Abstract] [PDF]  

M Kageyama, T Mori, T Yanagisawa, and N Taira

Is staurosporine a specific inhibitor of protein kinase C in intact porcine coronary arteries?
J Pharmacol Exp Ther 1991 259: 1019-1026. [Abstract] [PDF]  

A Dedeoglu and LA Fisher

Central and peripheral injections of the 5-HT2 agonist, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane, modify cardiovascular function through different mechanisms
J Pharmacol Exp Ther 1991 259: 1027-1034. [Abstract] [PDF]  

AJ de Brum-Fernandes, G Guillemette, P Borgeat, and P Sirois

Specific binding sites for leukotriene B4 in guinea pig brain membranes
J Pharmacol Exp Ther 1991 259: 1035-1042. [Abstract] [PDF]  

GA FitzGerald, M Lupinetti, SA Charman, and WN Charman

Presystemic acetylation of platelets by aspirin: reduction in rate of drug delivery to improve biochemical selectivity for thromboxane A2
J Pharmacol Exp Ther 1991 259: 1043-1049. [Abstract] [PDF]  

M Roberts, SB Hladky, RJ Pickles, and AW Cuthbert

Stimulation of sodium transport by duramycin in cultured human colonic epithelia
J Pharmacol Exp Ther 1991 259: 1050-1058. [Abstract] [PDF]  

V Coutant-Perronne, H Mansour, C Marquetty, B Rouveix, and JJ Pocidalo

Activities of lung NADPH-cytochrome C-reductase and of cytochrome P-450 peroxidase during the protection of rat from hyperoxic injury by polyriboinosinic acid-polyribocytidilic acid
J Pharmacol Exp Ther 1991 259: 1059-1063. [Abstract] [PDF]  

G Damsma, GS Robertson, CS Tham, and HC Fibiger

Dopaminergic regulation of striatal acetylcholine release: importance of D1 and N-methyl-D-aspartate receptors
J Pharmacol Exp Ther 1991 259: 1064-1072. [Abstract] [PDF]  

JJ Rady, JM Fujimoto, and LF Tseng

Dynorphins other than dynorphin A(1-17) lack spinal antianalgesic activity but do act on dynorphin A(1-17) receptors
J Pharmacol Exp Ther 1991 259: 1073-1080. [Abstract] [PDF]  

D Clarke and LC Garg

Alpha-1 adrenergic receptors in renal medullary collecting duct cells
J Pharmacol Exp Ther 1991 259: 1081-1087. [Abstract] [PDF]  

L Zhang and JE Barrett

Imipramine as a discriminative stimulus
J Pharmacol Exp Ther 1991 259: 1088-1093. [Abstract] [PDF]  

DA Taylor, JA Leedham, LE Bennett, and WW Fleming

Effects of GABA in the morphine-tolerant longitudinal muscle, myenteric plexus preparation of the guinea pig
J Pharmacol Exp Ther 1991 259: 1094-1101. [Abstract] [PDF]  

K Ishii, TD Warner, H Sheng, and F Murad

Endothelin increases cyclic GMP levels in LLC-PK1 porcine kidney epithelial cells via formation of an endothelium-derived relaxing factor-like substance
J Pharmacol Exp Ther 1991 259: 1102-1108. [Abstract] [PDF]  

SJ Weber, DL Greene, SD Sharma, HI Yamamura, TH Kramer, TF Burks, VJ Hruby, LB Hersh, and TP Davis

Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration
J Pharmacol Exp Ther 1991 259: 1109-1117. [Abstract] [PDF]  

CJ Hillard and JJ Pounds

[3H]tetraphenylphosphonium accumulation in cerebral cortical synaptosomes as a measure of nicotine-induced changes in membrane potential
J Pharmacol Exp Ther 1991 259: 1118-1123. [Abstract] [PDF]  

MM Gleason and JP Hieble

Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung
J Pharmacol Exp Ther 1991 259: 1124-1132. [Abstract] [PDF]  

AC Rudy, PM Knight, DC Brater, and SD Hall

Stereoselective metabolism of ibuprofen in humans: administration of R- , S- and racemic ibuprofen [published erratum appears in J Pharmacol Exp Ther 1992 Mar;260(3):1456]
J Pharmacol Exp Ther 1991 259: 1133-1139. [Abstract] [PDF]  

K Matsunaga and RF Furchgott

Responses of rabbit aorta to nitric oxide and superoxide generated by ultraviolet irradiation of solutions containing inorganic nitrite
J Pharmacol Exp Ther 1991 259: 1140-1146. [Abstract] [PDF]  

DA Schwinn, C Correa-Sales, SO Page, and M Maze

Functional effects of activation of alpha-1 adrenoceptors by dexmedetomidine: in vivo and in vitro studies
J Pharmacol Exp Ther 1991 259: 1147-1152. [Abstract] [PDF]  

G Bonanno, A Gemignani, E Fedele, G Fontana, and M Raiteri

gamma-Aminobutyric acidB receptors mediate inhibition of somatostatin release from cerebrocortex nerve terminals
J Pharmacol Exp Ther 1991 259: 1153-1157. [Abstract] [PDF]  

TL Grant and JS Zuzack

Effects of K+ channel blockers and cromakalim (BRL 34915) on the mechanical activity of guinea pig detrusor smooth muscle
J Pharmacol Exp Ther 1991 259: 1158-1164. [Abstract] [PDF]  

RJ Lamb, KL Preston, CW Schindler, RA Meisch, F Davis, JL Katz, JE Henningfield, and SR Goldberg

The reinforcing and subjective effects of morphine in post-addicts: a dose-response study
J Pharmacol Exp Ther 1991 259: 1165-1173. [Abstract] [PDF]  

DR Luthin and WH Cline

Evidence for enhanced inhibitory modulation by cyclooxygenase products of noradrenergic neurotransmission in the mesenteric vasculature of young spontaneously hypertensive rats
J Pharmacol Exp Ther 1991 259: 1174-1181. [Abstract] [PDF]  

PJ Rice, JC Hardin, A Hamdi, and ST Abraham

Imidazoline desensitization of epinephrine responses in rat vas deferens
J Pharmacol Exp Ther 1991 259: 1182-1187. [Abstract] [PDF]  

ME Reith, AE Jacobson, KC Rice, M Benuck, and I Zimanyi

Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel
J Pharmacol Exp Ther 1991 259: 1188-1196. [Abstract] [PDF]  

GR Hanson, N Singh, L Bush, and JW Gibb

Response of extrapyramidal and limbic neuropeptides to fenfluramine administration: comparison with methamphetamine
J Pharmacol Exp Ther 1991 259: 1197-1202. [Abstract] [PDF]  

RL Webb, BW Barclay, and SC Graybill

Cardiovascular effects of adenosine A2 agonists in the conscious spontaneously hypertensive rat: a comparative study of three structurally distinct ligands
J Pharmacol Exp Ther 1991 259: 1203-1212. [Abstract] [PDF]  

DG Fraser and JF Regal

Recombinant human C5a-induced bronchoconstriction in the guinea pig: inhibition by an H1 antagonist after depletion of circulating granulocytes and platelets
J Pharmacol Exp Ther 1991 259: 1213-1220. [Abstract] [PDF]  

KH Park, JP Long, and JG Cannon

Evaluation of the central and peripheral components for induction of postural hypotension by guanethidine, clonidine, dopamine2 receptor agonists and 5-hydroxytryptamine1A receptor agonists
J Pharmacol Exp Ther 1991 259: 1221-1230. [Abstract] [PDF]  

WA Mann, GE Welzel, RS Goldstein, RS Sozio, MJ Cyronak, J Kao, and LB Kinter

Characterization of the renal effects and renal elimination of sulotroban in the dog
J Pharmacol Exp Ther 1991 259: 1231-1240. [Abstract] [PDF]  

AE Cribb, DM Grant, MA Miller, and SP Spielberg

Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes
J Pharmacol Exp Ther 1991 259: 1241-1246. [Abstract] [PDF]  

P Camus, B Coudert, P D'Athis, P Foucher, J Delchambre, A Dupront, and L Jeannin

Pharmacokinetics and metabolism of nilutamide in the isolated rat lung
J Pharmacol Exp Ther 1991 259: 1247-1255. [Abstract] [PDF]  

Y Yamashita, T Yukimura, K Miura, M Okumura, and K Yamamoto

Effects of endothelin-3 on renal functions
J Pharmacol Exp Ther 1991 259: 1256-1260. [Abstract] [PDF]  

DC Mays, KF Dixon, A Balboa, LJ Pawluk, MR Bauer, S Nawoot, and N Gerber

A nonprimate animal model applicable to zidovudine pharmacokinetics in humans: inhibition of glucuronidation and renal excretion of zidovudine by probenecid in rats
J Pharmacol Exp Ther 1991 259: 1261-1270. [Abstract] [PDF]  

PF Cardoso, M Spino, E Mayer, SQ Shi, RD Pop, J Puskas, D Perrier, J Tong, AD Baines, and GA Patterson

Use of an isolated in situ canine lung perfusion model to evaluate dopamine clearance by the lung
J Pharmacol Exp Ther 1991 259: 1271-1276. [Abstract] [PDF]  

DP Brooks, RM Edwards, PD Depalma, TA Fredrickson, JP Hieble, and M Gellai

The water diuretic effect of the alpha-2 adrenoceptor agonist, AGN 190851, is species-dependent
J Pharmacol Exp Ther 1991 259: 1277-1282. [Abstract] [PDF]  

PP Sokol

Mechanism of vancomycin transport in the kidney: studies in rabbit renal brush border and basolateral membrane vesicles
J Pharmacol Exp Ther 1991 259: 1283-1287. [Abstract] [PDF]  

PE Simson, HE Criswell, and GR Breese

Ethanol potentiates gamma-aminobutyric acid-mediated inhibition in the inferior colliculus: evidence for local ethanol/gamma-aminobutyric acid interactions
J Pharmacol Exp Ther 1991 259: 1288-1293. [Abstract] [PDF]  

WL Hasler, A Heldsinger, and C Owyang

Cisapride acts on muscarinic (glandular M2) receptors to induce contraction of isolated gastric myocytes: mediation via a calcium- phosphoinositide pathway
J Pharmacol Exp Ther 1991 259: 1294-1300. [Abstract] [PDF]  

X Chen, SE Orfanos, JW Ryan, AY Chung, DC Hess, and JD Catravas

Species variation in pulmonary endothelial aminopeptidase P activity
J Pharmacol Exp Ther 1991 259: 1301-1307. [Abstract] [PDF]  

A d'Amore, P Lorenzini, and M Massotti

Antinociceptive action of opiates and opioid peptides after unilateral microinjection into area tempestas in rats
J Pharmacol Exp Ther 1991 259: 1308-1315. [Abstract] [PDF]  

RE Purdy and MR Milburn

Evidence against serotonin-induced endothelium-dependent relaxation in bovine coronary artery
J Pharmacol Exp Ther 1991 259: 1316-1322. [Abstract] [PDF]  

R Bascom, A Kagey-Sobotka, and D Proud

Effect of intranasal capsaicin on symptoms and mediator release
J Pharmacol Exp Ther 1991 259: 1323-1327. [Abstract] [PDF]  

C Pons, PM Dansette, C Amar, M Jaouen, CR Wolf, J Gregeois, JC Homberg, and D Mansuy

Detection of human hepatitis anti-liver kidney microsomes (LKM2) autoantibodies on rat liver sections is predominantly due to reactivity with rat liver P-450 IIC11
J Pharmacol Exp Ther 1991 259: 1328-1334. [Abstract] [PDF]  

CJ Helke, KB Thor, and ET Phillips

5-Hydroxytryptamine1C/2 agonists in the thoracic spinal cord: cardiovascular effects and binding sites in the intermediolateral cell column
J Pharmacol Exp Ther 1991 259: 1335-1343. [Abstract] [PDF]  

HX Yu and JT Turner

Functional studies in the human submandibular duct cell line, HSG-PA, suggest a second salivary gland receptor subtype for nucleotides
J Pharmacol Exp Ther 1991 259: 1344-1350. [Abstract] [PDF]  

AJ Fischman, NM Alpert, E Livni, S Ray, I Sinclair, DR Elmaleh, S Weiss, JA Correia, D Webb, and R Liss

Pharmacokinetics of 18F-labeled fluconazole in rabbits with candidal infections studied with positron emission tomography
J Pharmacol Exp Ther 1991 259: 1351-1359. [Abstract] [PDF]  

P Boulenguez, J Chauveau, L Segu, A Morel, M Delaage, and J Lanoir

Pharmacological characterization of serotonin-O-carboxymethyl-glycyl- tyrosinamide, a new selective indolic ligand for 5-hydroxytryptamine (5- HT)1B and 5-HT1D binding sites
J Pharmacol Exp Ther 1991 259: 1360-1365. [Abstract] [PDF]  

AI Sacaan, JA Monn, and DD Schoepp

Intrastriatal injection of a selective metabotropic excitatory amino acid receptor agonist induces contralateral turning in the rat
J Pharmacol Exp Ther 1991 259: 1366-1370. [Abstract] [PDF]  

SC Lam, JP Dieter, LC Strebel, TM Taylor, G Muscolino, H Feinberg, and GC Le Breton

Rapid dissociation of platelet-rich fibrin clots in vitro by a combination of plasminogen activators and antiplatelet agents
J Pharmacol Exp Ther 1991 259: 1371-1378. [Abstract] [PDF]  

SC Hu, FW Chang, YJ Sung, WM Hsu, and EH Lee

Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the substantia nigra and the locus coeruleus in BALB/c mice
J Pharmacol Exp Ther 1991 259: 1379-1387. [Abstract] [PDF]  

TP Abrahams, PJ Hornby, DP Walton, AM Taveira DaSilva, and RA Gillis

An excitatory amino acid(s) in the ventrolateral medulla is (are) required for breathing to occur in the anesthetized cat
J Pharmacol Exp Ther 1991 259: 1388-1395. [Abstract] [PDF]  

M Kamouchi, Z Xiong, N Teramoto, S Kajioka, K Okabe, and K Kitamura

Ionic currents involved in vasodilating actions of E4080, a newly synthesized bradycardia-inducing agent, in dispersed smooth muscle cells of the rabbit portal vein
J Pharmacol Exp Ther 1991 259: 1396-1403. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1991 259: 1404. [Abstract] [PDF]  

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