ARTICLES:

A Georg and A Friedl

Identification and characterization of two sigma-like binding sites in the mouse neuroblastoma x rat glioma hybrid cell line NG108-15
J Pharmacol Exp Ther 1991 259: 479-483. [Abstract] [PDF]  

M Ohara-Imaizumi, K Nakazawa, T Obama, K Fujimori, A Takanaka, and K Inoue

Inhibitory action of peripheral-type benzodiazepines on dopamine release from PC12 pheochromocytoma cells
J Pharmacol Exp Ther 1991 259: 484-489. [Abstract] [PDF]  

G Thomas and PW Ramwell

Effects of guanidino compounds on the endothelium-derived relaxing factor inhibitor NG-monomethyl L-arginine
J Pharmacol Exp Ther 1991 259: 490-494. [Abstract] [PDF]  

AD Levy, QA Li, JE Kerr, PA Rittenhouse, G Milonas, TM Cabrera, G Battaglia, MC Alvarez Sanz, and LD Van de Kar

Cocaine-induced elevation of plasma adrenocorticotropin hormone and corticosterone is mediated by serotonergic neurons
J Pharmacol Exp Ther 1991 259: 495-500. [Abstract] [PDF]  

MD Linnik, BT Butler, RR Gaddis, and NK Ahmed

Analysis of serotonergic mechanisms underlying benzamide-induced gastroprokinesis
J Pharmacol Exp Ther 1991 259: 501-507. [Abstract] [PDF]  

MH Sabouni, DJ Cushing, SR Makujina, and SJ Mustafa

Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery
J Pharmacol Exp Ther 1991 259: 508-512. [Abstract] [PDF]  

T Katsuragi, T Tokunaga, S Ogawa, O Soejima, C Sato, and T Furukawa

Existence of ATP-evoked ATP release system in smooth muscles
J Pharmacol Exp Ther 1991 259: 513-518. [Abstract] [PDF]  

EA Kowaluk and HL Fung

Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct
J Pharmacol Exp Ther 1991 259: 519-525. [Abstract] [PDF]  

C Borg, S Mondot, M Mestre, and I Cavero

Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin
J Pharmacol Exp Ther 1991 259: 526-534. [Abstract] [PDF]  

TL Dise, A Stolfi, CW Clarkson, and AS Pickoff

Rate-dependent effects of lidocaine on His-Purkinje conduction in the intact neonatal heart--characterization and amplification by N- acetylprocainamide
J Pharmacol Exp Ther 1991 259: 535-542. [Abstract] [PDF]  

TP Su, XZ Wu, EJ Cone, K Shukla, TM Gund, AL Dodge, and DW Parish

Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand
J Pharmacol Exp Ther 1991 259: 543-550. [Abstract] [PDF]  

F Boomsma, AJ Man in 't Veld, and MA Schalekamp

Not norepinephrine but its oxidation products bind specifically to plasma proteins
J Pharmacol Exp Ther 1991 259: 551-557. [Abstract] [PDF]  

E Patterson, BJ Scherlag, KD Berlin, and R Lazzara

Electrophysiological actions of BRB-I-28 in canine myocardial tissues
J Pharmacol Exp Ther 1991 259: 558-565. [Abstract] [PDF]  

S Zini, Y Ben-Ari, and ML Ashford

Characterization of sulfonylurea receptors and the action of potassium channel openers on cholinergic neurotransmission in guinea pig isolated small intestine
J Pharmacol Exp Ther 1991 259: 566-573. [Abstract] [PDF]  

NE Goeders

Cocaine differentially affects benzodiazepine receptors in discrete regions of the rat brain: persistence and potential mechanisms mediating these effects
J Pharmacol Exp Ther 1991 259: 574-581. [Abstract] [PDF]  

CA Paronis and SG Holtzman

Increased analgesic potency of mu agonists after continuous naloxone infusion in rats
J Pharmacol Exp Ther 1991 259: 582-589. [Abstract] [PDF]  

AS Nies, A Tunney, A Barden, M Sturm, and R Vandongen

Release of platelet activating factor by the isolated kidney is not linked to the production of prostaglandins
J Pharmacol Exp Ther 1991 259: 590-594. [Abstract] [PDF]  

JD Elsworth, MS Lawrence, RH Roth, JR Taylor, RB Mailman, DE Nichols, MH Lewis, and DE Jr Redmond

D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey
J Pharmacol Exp Ther 1991 259: 595-600. [Abstract] [PDF]  

JH Miller, VA Gibson, and M McKinney

Binding of [3H]AF-DX 384 to cloned and native muscarinic receptors
J Pharmacol Exp Ther 1991 259: 601-607. [Abstract] [PDF]  

P Stewart and L Isaac

Dynorphin-induced depression of the dorsal root potential in rat spinal cord: a possible mechanism for potentiation of the C-fiber reflex
J Pharmacol Exp Ther 1991 259: 608-613. [Abstract] [PDF]  

RC Carneiro, J Cipolla-Neto, and RP Markus

Diurnal variation of the rat vas deferens contraction induced by stimulation of presynaptic nicotinic receptors and pineal function
J Pharmacol Exp Ther 1991 259: 614-619. [Abstract] [PDF]  

H Matsushita, H Suzuki, Y Sugiyama, Y Sawada, T Iga, Y Kawaguchi, and M Hanano

Facilitated transport of cefodizime into the rat central nervous system
J Pharmacol Exp Ther 1991 259: 620-625. [Abstract] [PDF]  

IJ Reynolds, BM Baron, and ML Edwards

1,10-bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo
J Pharmacol Exp Ther 1991 259: 626-632. [Abstract] [PDF]  

CA Broomfield, DM Maxwell, RP Solana, CA Castro, AV Finger, and DE Lenz

Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates
J Pharmacol Exp Ther 1991 259: 633-638. [Abstract] [PDF]  

G Rubanyi, A Iqbal, A Schwartz, and PM Vanhoutte

Vascular actions of TA 3090, a novel analog of diltiazem: interaction with endothelium-dependent relaxation in canine femoral and coronary arteries
J Pharmacol Exp Ther 1991 259: 639-642. [Abstract] [PDF]  

JP Hieble, AC Sulpizio, R Edwards, H Chapman, P Young, SP Roberts, TP Blackburn, MD Wood, DH Shah, and RM Demarinis

Additional evidence for functional subclassification of alpha-2 adrenoceptors based on a new selective antagonist, SK&F 104856
J Pharmacol Exp Ther 1991 259: 643-652. [Abstract] [PDF]  

JQ Kong, DA Taylor, and WW Fleming

Antagonism of norepinephrine by clonidine in the isolated rat mesenteric vascular bed
J Pharmacol Exp Ther 1991 259: 653-658. [Abstract] [PDF]  

JB Calixto and YS Medeiros

Characterization of bradykinin mediating pertussis toxin-insensitive biphasic response in circular muscle of the isolated guinea pig ileum
J Pharmacol Exp Ther 1991 259: 659-665. [Abstract] [PDF]  

NF Voelkel and J Czartolomna

Vanadate potentiates hypoxic pulmonary vasoconstriction
J Pharmacol Exp Ther 1991 259: 666-672. [Abstract] [PDF]  

MC Olianas and P Onali

Muscarinic stimulation of adenylate cyclase activity of rat olfactory bulb. I. Analysis of agonist sensitivity
J Pharmacol Exp Ther 1991 259: 673-679. [Abstract] [PDF]  

MC Olianas and P Onali

Muscarinic stimulation of adenylate cyclase activity of rat olfactory bulb. II. Characterization of the antagonist sensitivity and comparison with muscarinic inhibitions of the enzyme in striatum and heart
J Pharmacol Exp Ther 1991 259: 680-686. [Abstract] [PDF]  

MG Cogan, FY Liu, PC Wong, and PB Timmermans

Comparison of inhibitory potency by nonpeptide angiotensin II receptor antagonists PD123177 and DuP 753 on proximal nephron and renal transport
J Pharmacol Exp Ther 1991 259: 687-691. [Abstract] [PDF]  

JM Desce, G Godeheu, T Galli, F Artaud, A Cheramy, and J Glowinski

Presynaptic facilitation of dopamine release through D,L-alpha-amino-3- hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum
J Pharmacol Exp Ther 1991 259: 692-698. [Abstract] [PDF]  

DW Hein, TD Rustan, KD Bucher, and LS Miller

Polymorphic and monomorphic expression of arylamine carcinogen N- acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus
J Pharmacol Exp Ther 1991 259: 699-704. [Abstract] [PDF]  

XM Wang, G Dayanithi, JR Lemos, JJ Nordmann, and SN Treistman

Calcium currents and peptide release from neurohypophysial terminals are inhibited by ethanol
J Pharmacol Exp Ther 1991 259: 705-711. [Abstract] [PDF]  

MK James, PL Feldman, SV Schuster, JM Bilotta, MF Brackeen, and HJ Leighton

Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues
J Pharmacol Exp Ther 1991 259: 712-718. [Abstract] [PDF]  

P Ashton, W Wang, and VH Lee

Location of penetration and metabolic barriers to levobunolol in the corneal epithelium of the pigmented rabbit
J Pharmacol Exp Ther 1991 259: 719-724. [Abstract] [PDF]  

EJ Drower, A Stapelfeld, MF Rafferty, BR de Costa, KC Rice, and DL Hammond

Selective antagonism by naltrindole of the antinociceptive effects of the delta opioid agonist cyclic[D-penicillamine2-D- penicillamine5]enkephalin in the rat
J Pharmacol Exp Ther 1991 259: 725-731. [Abstract] [PDF]  

K Noguchi, Y Ojiri, T Chibana, H Moromizato, and M Sakanashi

Cardiac effects of beta-2 adrenoceptor stimulation with intracoronary procaterol in the absence and presence of regional myocardial ischemia in dogs
J Pharmacol Exp Ther 1991 259: 732-737. [Abstract] [PDF]  

M Shirotani, Y Yui, R Hattori, and C Kawai

A new type of vasodilator, HA1077, an isoquinoline derivative, inhibits proliferation of bovine vascular smooth muscle cells in culture
J Pharmacol Exp Ther 1991 259: 738-744. [Abstract] [PDF]  

M Starec, B Rouveix, M Sinet, F Chau, B Desforges, JJ Pocidalo, and P Lechat

Immune status and survival of opiate- and cocaine-treated mice infected with Friend virus
J Pharmacol Exp Ther 1991 259: 745-750. [Abstract] [PDF]  

M O'Donnell, HJ Crowley, B Yaremko, N O'Neill, and AF Welton

Pharmacologic actions of Ro 24-5913, a novel antagonist of leukotriene D4
J Pharmacol Exp Ther 1991 259: 751-758. [Abstract] [PDF]  

P Geppetti, E Del Bianco, M Tramontana, T Vigano, GC Folco, CA Maggi, S Manzini, and M Fanciullacci

Arachidonic acid and bradykinin share a common pathway to release neuropeptide from capsaicin-sensitive sensory nerve fibers of the guinea pig heart
J Pharmacol Exp Ther 1991 259: 759-765. [Abstract] [PDF]  

JC Drieman and HH Thijssen

Renal selective N-acetyl-L-gamma-glutamyl prodrugs. III. N-acetyl-L- gamma-glutamyl-4'-aminowarfarin is not targeted to the kidney but is selectively excreted into the bile
J Pharmacol Exp Ther 1991 259: 766-771. [Abstract] [PDF]  

EA Walker, T Yamamoto, PJ Hollingsworth, CB Smith, and JH Woods

Discriminative-stimulus effects of quipazine and l-5-hydroxytryptophan in relation to serotonin binding sites in the pigeon
J Pharmacol Exp Ther 1991 259: 772-782. [Abstract] [PDF]  

XL Wang, E Wettwer, G Gross, and U Ravens

Reduction of cardiac outward currents by alpha-1 adrenoceptor stimulation: a subtype-specific effect?
J Pharmacol Exp Ther 1991 259: 783-788. [Abstract] [PDF]  

J Turgeon, C Fiset, R Giguere, M Gilbert, K Moerike, JR Rouleau, HK Kroemer, M Eichelbaum, O Grech-Belanger, and PM Belanger

Influence of debrisoquine phenotype and of quinidine on mexiletine disposition in man
J Pharmacol Exp Ther 1991 259: 789-798. [Abstract] [PDF]  

JR Hammond

Comparative pharmacology of the nitrobenzylthioguanosine-sensitive and - resistant nucleoside transport mechanisms of Ehrlich ascites tumor cells
J Pharmacol Exp Ther 1991 259: 799-807. [Abstract] [PDF]  

RM Maiorino, RC Dart, DE Carter, and HV Aposhian

Determination and metabolism of dithiol chelating agents. XII. Metabolism and pharmacokinetics of sodium 2,3-dimercaptopropane-1- sulfonate in humans
J Pharmacol Exp Ther 1991 259: 808-814. [Abstract] [PDF]  

K Miyata, T Kamato, M Yamano, A Nishida, H Ito, Y Katsuyama, H Yuki, R Tsutsumi, M Ohta, and M Takeda

Serotonin (5-HT)3 receptor blocking activities of YM060, a novel 4,5,6,7-tetrahydrobenzimidazole derivative, and its enantiomer in anesthetized rats
J Pharmacol Exp Ther 1991 259: 815-819. [Abstract] [PDF]  

JF Nash and J Brodkin

Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors
J Pharmacol Exp Ther 1991 259: 820-825. [Abstract] [PDF]  

DB Haughey and WJ Jusko

Effect of ketoconazole on methylprednisolone pharmacokinetics and receptor/gene-mediated pharmacodynamics
J Pharmacol Exp Ther 1991 259: 826-832. [Abstract] [PDF]  

TA French and N Weiner

Serotoninergic involvement in ethanol-induced alterations of thermoregulation in long-sleep and short-sleep mice
J Pharmacol Exp Ther 1991 259: 833-840. [Abstract] [PDF]  

G Engberg, T Elebring, and H Nissbrandt

Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons
J Pharmacol Exp Ther 1991 259: 841-847. [Abstract] [PDF]  

E MacDonald, M Scheinin, H Scheinin, and R Virtanen

Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist
J Pharmacol Exp Ther 1991 259: 848-854. [Abstract] [PDF]  

I Ringel and SB Horwitz

Effect of alkaline pH on taxol-microtubule interactions
J Pharmacol Exp Ther 1991 259: 855-860. [Abstract] [PDF]  

PC Wong, SD Hart, AT Chiu, WF Herblin, DJ Carini, RD Smith, RR Wexler, and PB Timmermans

Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist
J Pharmacol Exp Ther 1991 259: 861-870. [Abstract] [PDF]  

J Weissenburger, JM Davy, F Chezalviel, O Ertzbischoff, JM Poirier, F Engel, P Lainee, E Penin, G Motte, and G Cheymol

Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol
J Pharmacol Exp Ther 1991 259: 871-883. [Abstract] [PDF]  

T Shirayama, D Inoue, M Inoue, T Tatsumi, Y Yamahara, J Asayama, H Katsume, and M Nakagawa

Electrophysiological effects of sodium channel blockers on guinea pig left atrium
J Pharmacol Exp Ther 1991 259: 884-893. [Abstract] [PDF]  

D Deschamps, C Fisch, B Fromenty, A Berson, C Degott, and D Pessayre

Inhibition by salicylic acid of the activation and thus oxidation of long chain fatty acids. Possible role in the development of Reye's syndrome
J Pharmacol Exp Ther 1991 259: 894-904. [Abstract] [PDF]  

A Rego, R Vargas, S Cathapermal, M Kuwahara, ML Foegh, and PW Ramwell

Systemic vascular effects of cyclosporin A treatment in normotensive rats
J Pharmacol Exp Ther 1991 259: 905-915. [Abstract] [PDF]  

JD Steketee and PW Kalivas

Sensitization to psychostimulants and stress after injection of pertussis toxin into the A10 dopamine region
J Pharmacol Exp Ther 1991 259: 916-924. [Abstract] [PDF]  

CJ Stille and GL Stiles

Methylxanthine treatment of smooth muscle cells differentially modulates adenylate cyclase responsiveness
J Pharmacol Exp Ther 1991 259: 925-931. [Abstract] [PDF]  

SJ Hong and CC Chang

Hyperpolarization of denervated skeletal muscle by lemakalim and its antagonism by glybenclamide and tolbutamide
J Pharmacol Exp Ther 1991 259: 932-938. [Abstract] [PDF]  

S Nattel, N Turmel, R Macleod, and BC Solymoss

Actions of intravenous magnesium on ventricular arrhythmias caused by acute myocardial infarction
J Pharmacol Exp Ther 1991 259: 939-946. [Abstract] [PDF]  

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