ARTICLES:

DK Agrawal, DR Bergren, PJ Byorth, and RG Townley

Platelet-activating factor induces nonspecific desensitization to bronchodilators in guinea pigs
J Pharmacol Exp Ther 1991 259: 1-7. [Abstract] [PDF]  

RJ Klauser, W Raake, E Meinetsberger, and P Zeiller

Antithrombotic and anticoagulant properties of synthetic polyanions: sulfated bis-aldonic acid amides
J Pharmacol Exp Ther 1991 259: 8-14. [Abstract] [PDF]  

K Miyata, T Kamato, A Nishida, H Ito, Y Katsuyama, A Iwai, H Yuki, M Yamano, R Tsutsumi, and M Ohta

Pharmacologic profile of (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7- tetrahydro-1H- benzimidazole hydrochloride (YM060), a potent and selective 5-hydroxytryptamine3 receptor antagonist, and its enantiomer in the isolated tissue
J Pharmacol Exp Ther 1991 259: 15-21. [Abstract] [PDF]  

T Massamiri and SP Duckles

Sigma receptor ligands inhibit rat tail artery contractile responses by multiple mechanisms
J Pharmacol Exp Ther 1991 259: 22-29. [Abstract] [PDF]  

MA Rogawski, S Yamaguchi, SM Jones, KC Rice, A Thurkauf, and JA Monn

Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine
J Pharmacol Exp Ther 1991 259: 30-37. [Abstract] [PDF]  

LM Ren, Y Furukawa, Y Karasawa, M Murakami, M Takei, M Narita, and S Chiba

Differential inhibition of neuropeptide Y on the chronotropic and inotropic responses to sympathetic and parasympathetic stimulation in the isolated, perfused dog atrium
J Pharmacol Exp Ther 1991 259: 38-43. [Abstract] [PDF]  

JM Herbert, A Bernat, G Valette, V Gigo, A Lale, MC LaPlace, L Lespy, P Savi, JP Maffrand, and G Le Fur

Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist
J Pharmacol Exp Ther 1991 259: 44-51. [Abstract] [PDF]  

J Yamazaki, N Fujita, and T Nagao

NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats
J Pharmacol Exp Ther 1991 259: 52-57. [Abstract] [PDF]  

PA Rittenhouse, EA Bakkum, and LD Van de Kar

Evidence that the serotonin agonist, DOI, increases renin secretion and blood pressure through both central and peripheral 5-HT2 receptors
J Pharmacol Exp Ther 1991 259: 58-65. [Abstract] [PDF]  

WM Pardridge, JL Buciak, and PM Friden

Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo
J Pharmacol Exp Ther 1991 259: 66-70. [Abstract] [PDF]  

SN Joshi, AJ Lonigro, RJ Secrest, and BM Chapnick

Role of endothelium in responses of isolated hepatic vessels to vasoactive agents
J Pharmacol Exp Ther 1991 259: 71-77. [Abstract] [PDF]  

HJ Crowley, B Yaremko, WM Selig, DR Janero, C Burghardt, AF Welton, and M O'Donnell

Pharmacology of a potent platelet-activating factor antagonist: Ro 24- 4736
J Pharmacol Exp Ther 1991 259: 78-85. [Abstract] [PDF]  

Y Yoneda and K Ogita

Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques
J Pharmacol Exp Ther 1991 259: 86-96. [Abstract] [PDF]  

CA Sargent, MA Smith, S Dzwonczyk, PG Sleph, and GJ Grover

Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents
J Pharmacol Exp Ther 1991 259: 97-103. [Abstract] [PDF]  

AC Myers and BJ Undem

Functional interactions between capsaicin-sensitive and cholinergic nerves in the guinea pig bronchus
J Pharmacol Exp Ther 1991 259: 104-109. [Abstract] [PDF]  

LJ Janssen and EE Daniel

Depolarizing agents induce oscillations in canine bronchial smooth muscle membrane potential: possible mechanisms
J Pharmacol Exp Ther 1991 259: 110-117. [Abstract] [PDF]  

MS D'Almeida and WW Lautt

Glucagon pharmacodynamics and modulation of sympathetic nerve and norepinephrine-induced constrictor responses in the superior mesenteric artery of the cat
J Pharmacol Exp Ther 1991 259: 118-123. [Abstract] [PDF]  

MO Carruba, E Nisoli, V Garosi, M Pizzi, M Memo, and P Spano

Characterization of monoaminergic receptors in hypothalamic nuclei mediating feeding behavior in rats
J Pharmacol Exp Ther 1991 259: 124-130. [Abstract] [PDF]  

RD Bunag, D Krizsan-Agbas, and H Itoh

Sympathetic activation by chronic insulin treatment in conscious rats
J Pharmacol Exp Ther 1991 259: 131-138. [Abstract] [PDF]  

BJ Aungst, JA Blake, and MA Hussain

An in vitro evaluation of metabolism and poor membrane permeation impeding intestinal absorption of leucine enkephalin, and methods to increase absorption
J Pharmacol Exp Ther 1991 259: 139-145. [Abstract] [PDF]  

D Aharony, CA Catanese, and DP Woodhouse

Binding of the novel ligand [4,5-3H-Leu10]substance P to high-affinity NK-1 receptors on guinea pig lung membranes: modulation by GTP analogs and sulfhydryl modifying agents
J Pharmacol Exp Ther 1991 259: 146-155. [Abstract] [PDF]  

JB Pritchard, R Walden, and A Oikari

Dehydroabietic acid, a major anionic contaminant of pulp mill effluent, reduces both active p-aminohippurate transport and passive membrane permeability in isolated renal membranes
J Pharmacol Exp Ther 1991 259: 156-163. [Abstract] [PDF]  

L Rakotoarisoa, C Mironneau, I Sayet, and J Mironneau

Guanine nucleotide-binding proteins modulate desmethoxyverapamil binding to calcium channels in vascular smooth muscle
J Pharmacol Exp Ther 1991 259: 164-168. [Abstract] [PDF]  

AM Bendele, SM Spaethe, DN Benslay, and HU Bryant

Anti-inflammatory activity of pergolide, a dopamine receptor agonist
J Pharmacol Exp Ther 1991 259: 169-175. [Abstract] [PDF]  

DC Eikenburg

Age-related changes in vascular sympathetic neurotransmission in the rat kidney
J Pharmacol Exp Ther 1991 259: 176-181. [Abstract] [PDF]  

E Aceto and M Vassalle

On the mechanism of the positive inotropy of low concentrations of strophanthidin
J Pharmacol Exp Ther 1991 259: 182-189. [Abstract] [PDF]  

C Dedieu-Chaufour, F Hertz, F Caussade, and A Cloarec

Pharmacological profile of UP 5145-52, an original antiulcer and antisecretory agent
J Pharmacol Exp Ther 1991 259: 190-197. [Abstract] [PDF]  

KJ Morrison and PM Vanhoutte

Inhibition of airway smooth muscle tone by a phorbol ester in the guinea pig trachea: role of epithelium and receptor reserve of the contractile agent
J Pharmacol Exp Ther 1991 259: 198-204. [Abstract] [PDF]  

T Sakurada, T Yamada, K Tan-no, Y Manome, S Sakurada, K Kisara, and M Ohba

Differential effects of substance P analogs on neurokinin 1 receptor agonists in the mouse spinal cord
J Pharmacol Exp Ther 1991 259: 205-210. [Abstract] [PDF]  

CS Park, TW Honeyman, SK Ha, HK Choi, CL Chung, and CD Hong

Mechanisms of ionophore-induced stimulation of renin secretion with special reference to a chemiosmotic hypothesis
J Pharmacol Exp Ther 1991 259: 211-218. [Abstract] [PDF]  

NR Levens, D Cote, and G Ksander

Inhibition of thromboxane synthetase potentiates the antihypertensive action of an angiotensin-converting enzyme inhibitor by a prostaglandin- dependent but kinin-independent mechanism
J Pharmacol Exp Ther 1991 259: 219-227. [Abstract] [PDF]  

GW 2d Dorn

Mechanism for homologous downregulation of thromboxane A2 receptors in cultured human chronic myelogenous leukemia (K562) cells
J Pharmacol Exp Ther 1991 259: 228-234. [Abstract] [PDF]  

M Nakahiro, O Arakawa, and T Narahashi

Modulation of gamma-aminobutyric acid receptor-channel complex by alcohols
J Pharmacol Exp Ther 1991 259: 235-240. [Abstract] [PDF]  

JM Farley, JG Adderholt, and TM Dwyer

Cocaine and tracheal epithelial function: effects on short circuit current and neurotransmitter receptors
J Pharmacol Exp Ther 1991 259: 241-247. [Abstract] [PDF]  

AH Tang, SR Franklin, CS Himes, and PM Ho

Behavioral effects of U-78875, a quinoxalinone anxiolytic with potent benzodiazepine antagonist activity
J Pharmacol Exp Ther 1991 259: 248-254. [Abstract] [PDF]  

MD Johnson, HY Wang, D Ciechanowski, and E Friedman

Reduced G protein function in desensitized rat aorta
J Pharmacol Exp Ther 1991 259: 255-259. [Abstract] [PDF]  

JF French, LE Lambert, and RC Dage

Nitric oxide synthase inhibitors inhibit interleukin-1 beta-induced depression of vascular smooth muscle
J Pharmacol Exp Ther 1991 259: 260-264. [Abstract] [PDF]  

JK Saha, JN Sengupta, and RK Goyal

Effects of bradykinin and bradykinin analogs on the opossum lower esophageal sphincter: characterization of an inhibitory bradykinin receptor
J Pharmacol Exp Ther 1991 259: 265-273. [Abstract] [PDF]  

J Hidalgo, M Giralt, JS Garvey, and A Armario

Effect of morphine administration on rat liver metallothionein and zinc metabolism
J Pharmacol Exp Ther 1991 259: 274-278. [Abstract] [PDF]  

MG Lopez, F Abad, C Sancho, R de Pascual, R Borges, R Maroto, W Dixon, and AG Garcia

Membrane-mediated effects of the steroid 17-alpha-estradiol on adrenal catecholamine release
J Pharmacol Exp Ther 1991 259: 279-285. [Abstract] [PDF]  

O Nikodijevic, R Sarges, JW Daly, and KA Jacobson

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism
J Pharmacol Exp Ther 1991 259: 286-294. [Abstract] [PDF]  

JA Leedham, LE Bennett, DA Taylor, and WW Fleming

Involvement of mu, delta and kappa receptors in morphine-induced tolerance in the guinea pig myenteric plexus
J Pharmacol Exp Ther 1991 259: 295-301. [Abstract] [PDF]  

MM Belcheva, J Barg, RJ McHale, XM Gao, DM Chuang, and CJ Coscia

Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone
J Pharmacol Exp Ther 1991 259: 302-309. [Abstract] [PDF]  

A Rengasamy and RA Johns

Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions
J Pharmacol Exp Ther 1991 259: 310-316. [Abstract] [PDF]  

P Arner, E Kriegholm, and P Engfeldt

In vivo interactions between beta-1 and beta-2 adrenoceptors regulate catecholamine tachyphylaxia in human adipose tissue
J Pharmacol Exp Ther 1991 259: 317-322. [Abstract] [PDF]  

HS Blaxall, TJ Murphy, JC Baker, C Ray, and DB Bylund

Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line
J Pharmacol Exp Ther 1991 259: 323-329. [Abstract] [PDF]  

LF Tseng and KA Collins

Involvement of epsilon and kappa opioid receptors in inhibition of the tail-flick response induced by bremazocine in the mouse
J Pharmacol Exp Ther 1991 259: 330-336. [Abstract] [PDF]  

BJ Ebersole and PB Molinoff

Inhibition of binding of [3H]PN200-110 to membranes from rat brain and heart by ascorbate is mediated by lipid peroxidation
J Pharmacol Exp Ther 1991 259: 337-344. [Abstract] [PDF]  

M Buonamici, S Mantegani, MA Cervini, R Maj, AC Rossi, C Caccia, N Carfagna, P Carminati, and RG Fariello

FCE 23884, substrate-dependent interaction with the dopaminergic system. I. Preclinical behavioral studies
J Pharmacol Exp Ther 1991 259: 345-355. [Abstract] [PDF]  

N Carfagna, C Caccia, S Mantegani, S Cavanus, MG Fornaretto, M Buonamici, AC Rossi, R Roncucci, and RG Fariello

FCE 23884, substrate-dependent interaction with the dopaminergic system. II. Preclinical biochemical studies
J Pharmacol Exp Ther 1991 259: 356-364. [Abstract] [PDF]  

F Ikomi, Y Kawai, and T Ohhashi

Beta-1 and beta-2 adrenoceptors mediate smooth muscle relaxation in bovine isolated mesenteric lymphatics
J Pharmacol Exp Ther 1991 259: 365-370. [Abstract] [PDF]  

T Ohrui, K Sekizawa, K Yamauchi, Y Ohkawara, H Nakazawa, T Aikawa, H Sasaki, and T Takishima

Chemical oxidant potentiates electrically and acetylcholine-induced contraction in rat trachea: possible involvement of cholinesterase inhibition
J Pharmacol Exp Ther 1991 259: 371-376. [Abstract] [PDF]  

KL Swanson, RS Aronstam, S Wonnacott, H Rapoport, and EX Albuquerque

Nicotinic pharmacology of anatoxin analogs. I. Side chain structure- activity relationships at peripheral agonist and noncompetitive antagonist sites
J Pharmacol Exp Ther 1991 259: 377-386. [Abstract] [PDF]  

S Wonnacott, S Jackman, KL Swanson, H Rapoport, and EX Albuquerque

Nicotinic pharmacology of anatoxin analogs. II. Side chain structure- activity relationships at neuronal nicotinic ligand binding sites
J Pharmacol Exp Ther 1991 259: 387-391. [Abstract] [PDF]  

MJ Marks, SM Campbell, E Romm, and AC Collins

Genotype influences the development of tolerance to nicotine in the mouse
J Pharmacol Exp Ther 1991 259: 392-402. [Abstract] [PDF]  

FJ Carmichael, Y Israel, M Crawford, K Minhas, V Saldivia, S Sandrin, P Campisi, and H Orrego

Central nervous system effects of acetate: contribution to the central effects of ethanol
J Pharmacol Exp Ther 1991 259: 403-408. [Abstract] [PDF]  

B Gomez-Mancilla and PJ Bedard

Effect of D1 and D2 agonists and antagonists on dyskinesia produced by L-dopa in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys
J Pharmacol Exp Ther 1991 259: 409-413. [Abstract] [PDF]  

R Zini, D Morin, P Martin, AJ Puech, and JP Tillement

Interactions of flerobuterol, an antidepressant drug candidate, with beta adrenoceptors in the rat brain
J Pharmacol Exp Ther 1991 259: 414-422. [Abstract] [PDF]  

KJ Ivins and PB Molinoff

Desensitization and down-regulation of 5-HT2 receptors in P11 cells
J Pharmacol Exp Ther 1991 259: 423-429. [Abstract] [PDF]  

D Bleakman, PS Chard, S Foucart, and RJ Miller

Block of neuronal Ca++ influx by the anti-ischemic agent TA3090
J Pharmacol Exp Ther 1991 259: 430-438. [Abstract] [PDF]  

G Suarez-Kurtz, ML Garcia, and GJ Kaczorowski

Effects of charybdotoxin and iberiotoxin on the spontaneous motility and tonus of different guinea pig smooth muscle tissues
J Pharmacol Exp Ther 1991 259: 439-443. [Abstract] [PDF]  

DW Thibeault, G Downing, N Reddy, AJ Sonderfan, and A Parkinson

Oxygen-induced lung damage in newborn rats, potentiated by 3- methylcholanthrene, a P-450 inducer, and lack of protection by cimetidine, a P-450 inhibitor
J Pharmacol Exp Ther 1991 259: 444-451. [Abstract] [PDF]  

SD Skaper, A Leon, and L Facci

Death of cultured hippocampal pyramidal neurons induced by pathological activation of N-methyl-D-aspartate receptors is reduced by monosialogangliosides
J Pharmacol Exp Ther 1991 259: 452-457. [Abstract] [PDF]  

Z Argov, S Nioka, S Eleff, and B Chance

Effects of intra-arterial epinephrine on energy metabolism in exercising rabbit gastrocnemius muscle, studied by in vivo phosphorus nuclear magnetic resonance
J Pharmacol Exp Ther 1991 259: 458-463. [Abstract] [PDF]  

K Grasing and H Szeto

Naloxone causes a dose-dependent increase in total power and delta wave activity in the EEG of opioid-naive rats
J Pharmacol Exp Ther 1991 259: 464-469. [Abstract] [PDF]  

SG Kim, RM Philpot, and RF Novak

Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases
J Pharmacol Exp Ther 1991 259: 470-477. [Abstract] [PDF]  

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