ARTICLES:

J Nishimura and C van Breemen

Energetic aspects of the regulation of Ca++ sensitivity of permeabilized rabbit mesenteric artery: possible involvement of a second Ca++ regulatory system in smooth muscle contraction
J Pharmacol Exp Ther 1991 258: 397-402. [Abstract] [PDF]  

K Elrod and JJ Buccafusco

Correlation of the amnestic effects of nicotinic antagonists with inhibition of regional brain acetylcholine synthesis in rats
J Pharmacol Exp Ther 1991 258: 403-409. [Abstract] [PDF]  

TL Smith

Selective effects of acute and chronic ethanol exposure on neuropeptide and guanine nucleotide stimulated phospholipase C activity in intact N1E-115 neuroblastoma
J Pharmacol Exp Ther 1991 258: 410-415. [Abstract] [PDF]  

SC Black, LG Chi, DX Mu, and BR Lucchesi

The antifibrillatory actions of UK-68,798, a class III antiarrhythmic agent
J Pharmacol Exp Ther 1991 258: 416-423. [Abstract] [PDF]  

T Huo and DP Healy

[3H]domperidone binding to the kidney inner medullary collecting duct dopamine-2K (DA2K) receptor
J Pharmacol Exp Ther 1991 258: 424-428. [Abstract] [PDF]  

WP Schiemann, KO Doggwiler, and IL Buxton

Action of adenosine in estrogen-primed nonpregnant guinea pig myometrium: characterization of the smooth muscle receptor and coupling to phosphoinositide metabolism
J Pharmacol Exp Ther 1991 258: 429-437. [Abstract] [PDF]  

Y Takano and TL Yaksh

Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2- ethoxy-1,2-dihydroquinoline, an irreversible antagonist
J Pharmacol Exp Ther 1991 258: 438-446. [Abstract] [PDF]  

SP Svensson, LG Martensson, N Grundstrom, RG Andersson, EJ Jr Cragoe, and JO Karlsson

Antagonistic effect of amiloride on alpha-2 adrenoceptor-mediated pigment aggregation: pharmacological heterogeneity between B-HT 920 and noradrenaline
J Pharmacol Exp Ther 1991 258: 447-451. [Abstract] [PDF]  

AS Adeagbo and KU Malik

Contribution of K+ channels to arachidonic acid-induced endothelium- dependent vasodilation in rat isolated perfused mesenteric arteries
J Pharmacol Exp Ther 1991 258: 452-458. [Abstract] [PDF]  

T Shimura, S Tabata, T Ohnishi, T Terasaki, and A Tsuji

Transport mechanism of a new behaviorally highly potent adrenocorticotropic hormone (ACTH) analog, ebiratide, through the blood- brain barrier
J Pharmacol Exp Ther 1991 258: 459-465. [Abstract] [PDF]  

Y Goshima, S Nakamura, and Y Misu

L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices
J Pharmacol Exp Ther 1991 258: 466-471. [Abstract] [PDF]  

L Beani, C Bianchi, L Ferraro, M Morari, M Simonato, G Spalluto, and S Tanganelli

Alpha-2 adrenoreceptor-mediated decrease in gamma-aminobutyric acid outflow in cortical slices and synaptosomes during morphine tolerance
J Pharmacol Exp Ther 1991 258: 472-476. [Abstract] [PDF]  

JA Sandberg and GD Olsen

Cocaine pharmacokinetics in the pregnant guinea pig
J Pharmacol Exp Ther 1991 258: 477-482. [Abstract] [PDF]  

W Loscher and C Rundfeldt

Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats
J Pharmacol Exp Ther 1991 258: 483-489. [Abstract] [PDF]  

C Barajas-Lopez, A Surprenant, and RA North

Adenosine A1 and A2 receptors mediate presynaptic inhibition and postsynaptic excitation in guinea pig submucosal neurons
J Pharmacol Exp Ther 1991 258: 490-495. [Abstract] [PDF]  

HJ Lee, NV Cozzi, and MH Weiler

Age-related differences in the effects of some muscarinic agents on acetylcholine release from rat neostriatal slices
J Pharmacol Exp Ther 1991 258: 496-501. [Abstract] [PDF]  

CP France, G Winger, F Medzihradsky, MR Seggel, KC Rice, and JH Woods

Mirfentanil: pharmacological profile of a novel fentanyl derivative with opioid and nonopioid effects
J Pharmacol Exp Ther 1991 258: 502-510. [Abstract] [PDF]  

HN Bhargava, VM Villar, A Gulati, and G Chari

Analgesic and hyperthermic effects of intravenously administered morphine in the rat are related to its serum levels
J Pharmacol Exp Ther 1991 258: 511-516. [Abstract] [PDF]  

AH Lichtman and BR Martin

Spinal and supraspinal components of cannabinoid-induced antinociception
J Pharmacol Exp Ther 1991 258: 517-523. [Abstract] [PDF]  

J Chan and DA Greenberg

Endothelin and calcium signaling in NG108-15 neuroblastoma x glioma cells
J Pharmacol Exp Ther 1991 258: 524-530. [Abstract] [PDF]  

JT Shirley and JB Cheng

Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes
J Pharmacol Exp Ther 1991 258: 531-536. [Abstract] [PDF]  

H Steen, R Oosting, and DK Meijer

Mechanisms for the uptake of cationic drugs by the liver: a study with tributylmethylammonium (TBuMA)
J Pharmacol Exp Ther 1991 258: 537-543. [Abstract] [PDF]  

E Mjanger and TL Yaksh

Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists
J Pharmacol Exp Ther 1991 258: 544-550. [Abstract] [PDF]  

AC Le Dain, BW Madsen, and RO Edeson

Naltrexone modulation of nicotinic acetylcholine receptor activity
J Pharmacol Exp Ther 1991 258: 551-558. [Abstract] [PDF]  

H Refsum, B Christensen, R Djurhuus, and PM Ueland

Interaction between methotrexate, "rescue" agents and cell proliferation as modulators of homocysteine export from cells in culture
J Pharmacol Exp Ther 1991 258: 559-566. [Abstract] [PDF]  

A Floch, L Tahraoui, P Sedivy, and I Cavero

The platelet activating factor receptor antagonist, RP 59227, blocks platelet activating factor receptors mediating liberation of reactive oxygen species in guinea pig macrophages and human polymorphonuclear leukocytes
J Pharmacol Exp Ther 1991 258: 567-575. [Abstract] [PDF]  

MJ Durcan, RG Lister, and M Linnoila

Evidence for central alpha-2 adrenoceptors, not imidazoline binding sites, mediating the ethanol-attenuating properties of alpha-2 adrenoceptor antagonists
J Pharmacol Exp Ther 1991 258: 576-582. [Abstract] [PDF]  

A Mattia, T Vanderah, HI Mosberg, and F Porreca

Lack of antinociceptive cross-tolerance between [D-Pen2, D- Pen5]enkephalin and [D-Ala2]deltorphin II in mice: evidence for delta receptor subtypes
J Pharmacol Exp Ther 1991 258: 583-587. [Abstract] [PDF]  

I Biaggioni, S Paul, A Puckett, and C Arzubiaga

Caffeine and theophylline as adenosine receptor antagonists in humans
J Pharmacol Exp Ther 1991 258: 588-593. [Abstract] [PDF]  

DA Di Monte, EY Wu, I Irwin, LE Delanney, and JW Langston

Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes
J Pharmacol Exp Ther 1991 258: 594-600. [Abstract] [PDF]  

M Morigi, D Macconi, E Riccardi, P Boccardo, P Zilio, T Bertani, and G Remuzzi

Platelet-activating factor receptor blocking reduces proteinuria and improves survival in lupus autoimmune mice
J Pharmacol Exp Ther 1991 258: 601-606. [Abstract] [PDF]  

H Wu, JT Turner, and SP Halenda

Activation of phospholipase D by E-series prostaglandins in human erythroleukemia cells
J Pharmacol Exp Ther 1991 258: 607-612. [Abstract] [PDF]  

N Bakry, Y Kamata, R Sorensen, and LL Simpson

Tetanus toxin and neuronal membranes: the relationship between binding and toxicity
J Pharmacol Exp Ther 1991 258: 613-619. [Abstract] [PDF]  

V Dorai, MC Hazard, J Paris, and R Delansorne

Lipolytic activity of progesterone and synthetic progestins on rat parametrial adipocytes in vitro
J Pharmacol Exp Ther 1991 258: 620-625. [Abstract] [PDF]  

KF Melia and RD Spealman

Pharmacological characterization of the discriminative-stimulus effects of GBR 12909
J Pharmacol Exp Ther 1991 258: 626-632. [Abstract] [PDF]  

L Grundemar, C Wahlestedt, and DJ Reis

Neuropeptide Y acts at an atypical receptor to evoke cardiovascular depression and to inhibit glutamate responsiveness in the brainstem
J Pharmacol Exp Ther 1991 258: 633-638. [Abstract] [PDF]  

Y Torrens, M Dietl, JC Beaujouan, and J Glowinski

Inhibitory effects of substance P and carbachol on the saturable sodium- dependent uptake process of myo-inositol in rat parotid gland
J Pharmacol Exp Ther 1991 258: 639-646. [Abstract] [PDF]  

CD Lind, RL Guerrant, A Kurosky, and JR Mathias

Purified choleragenoid does not induce migrating action potential complex activity in rabbit ileum in vivo
J Pharmacol Exp Ther 1991 258: 647-651. [Abstract] [PDF]  

GC Yaney, GA Stafford, JD Henstenberg, GW Sharp, and GA Weiland

Binding of the dihydropyridine calcium channel blocker (+)-[3H] isopropyl-4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-5-methoxycarbonyl-2, 6-dimethyl-3-pyridinecarboxylate (PN200-110) to RINm5F membranes and cells: characterization and functional significance
J Pharmacol Exp Ther 1991 258: 652-662. [Abstract] [PDF]  

N Uchimura and RA North

Baclofen and adenosine inhibit synaptic potentials mediated by gamma- aminobutyric acid and glutamate release in rat nucleus accumbens
J Pharmacol Exp Ther 1991 258: 663-668. [Abstract] [PDF]  

WH Folger, D Lawson, CS Wilcox, and JL Mehta

Response of rat thoracic aortic rings to thromboxane mimetic U-46,619: roles of endothelium-derived relaxing factor and thromboxane A2 release
J Pharmacol Exp Ther 1991 258: 669-675. [Abstract] [PDF]  

H Shimaji, H Shirahase, M Kanda, S Osumi, and K Kurahashi

Effect of accumulation of NKY-722, a water-soluble vasoselective Ca++ antagonist, on KCl-induced contraction in isolated canine mesenteric arteries
J Pharmacol Exp Ther 1991 258: 676-680. [Abstract] [PDF]  

JH Lee, SF Steinberg, and MR Rosen

A WB 4101-sensitive alpha-1 adrenergic receptor subtype modulates repolarization in canine Purkinje fibers
J Pharmacol Exp Ther 1991 258: 681-687. [Abstract] [PDF]  

ED Hall, JM Braughler, PA Yonkers, SL Smith, KL Linseman, ED Means, HM Scherch, PF Von Voigtlander, RA Lahti, and EJ Jacobsen

U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia
J Pharmacol Exp Ther 1991 258: 688-694. [Abstract] [PDF]  

BW Berry and F Jamali

Presystemic and systemic chiral inversion of R-(-)-fenoprofen in the rat
J Pharmacol Exp Ther 1991 258: 695-701. [Abstract] [PDF]  

DA Cox, PT Ellinor, TL Kirley, and MA Matlib

Identification of a 17-kDa protein associated with the peripheral-type benzodiazepine receptor in vascular and other smooth muscle types
J Pharmacol Exp Ther 1991 258: 702-709. [Abstract] [PDF]  

RB Pearce and CM Peterson

Studies of concanavalin A in nonobese diabetic mice. I. Prevention of insulin-dependent diabetes
J Pharmacol Exp Ther 1991 258: 710-715. [Abstract] [PDF]  

B Mukherjee, RB Pearce, B Formby, and CM Peterson

Studies of concanavalin A in nonobese diabetic mice. II. Lymphocyte tracking and phenotype responses
J Pharmacol Exp Ther 1991 258: 716-721. [Abstract] [PDF]  

AM Gillis, WM Lester, and R Keashly

Propafenone disposition and pharmacodynamics in normal and norepinephrine-induced cardiomyopathic rabbit hearts
J Pharmacol Exp Ther 1991 258: 722-727. [Abstract] [PDF]  

R Godbout, J Mantz, S Pirot, J Glowinski, and AM Thierry

Inhibitory influence of the mesocortical dopaminergic neurons on their target cells: electrophysiological and pharmacological characterization
J Pharmacol Exp Ther 1991 258: 728-738. [Abstract] [PDF]  

L Carpenter-Deyo, JR Duimstra, O Hedstrom, and DJ Reed

Toxicity to isolated hepatocytes caused by the intracellular calcium indicator, Quin 2
J Pharmacol Exp Ther 1991 258: 739-746. [Abstract] [PDF]  

L Carpenter-Deyo and DJ Reed

Involvement of calcium and iron in Quin 2 toxicity to isolated hepatocytes
J Pharmacol Exp Ther 1991 258: 747-752. [Abstract] [PDF]  

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