ARTICLES:

D Paul, CG Pick, LA Tive, and GW Pasternak

Pharmacological characterization of nalorphine, a kappa 3 analgesic
J Pharmacol Exp Ther 1991 257: 1-7. [Abstract] [PDF]  

AH Oliveto, MJ Picker, and LA Dykstra

Acute and chronic morphine administration: effects of mixed-action opioids in rats and squirrel monkeys responding under a schedule of food presentation
J Pharmacol Exp Ther 1991 257: 8-18. [Abstract] [PDF]  

E Agneter, H Drobny, and EA Singer

Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition
J Pharmacol Exp Ther 1991 257: 19-25. [Abstract] [PDF]  

CK Buckner, D Dea, N Liberati, and RD Krell

A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig
J Pharmacol Exp Ther 1991 257: 26-34. [Abstract] [PDF]  

L Farraway and JD Huizinga

Potassium channel activation by cromakalim affects the slow wave type action potential of colonic smooth muscle
J Pharmacol Exp Ther 1991 257: 35-41. [Abstract] [PDF]  

RD McQuade, RA Duffy, VL Coffin, RE Chipkin, and A Barnett

In vivo binding of SCH 39166: a D-1 selective antagonist
J Pharmacol Exp Ther 1991 257: 42-49. [Abstract] [PDF]  

KH Park and JP Long

Modulation by physostigmine of head-up tilt- and bilateral carotid occlusion-induced baroreflexes in rats
J Pharmacol Exp Ther 1991 257: 50-55. [Abstract] [PDF]  

JT Eells

Methanol-induced visual toxicity in the rat
J Pharmacol Exp Ther 1991 257: 56-63. [Abstract] [PDF]  

Z Yu and JH McNeill

Altered inotropic responses in diabetic cardiomyopathy and hypertensive- diabetic cardiomyopathy
J Pharmacol Exp Ther 1991 257: 64-71. [Abstract] [PDF]  

NL Ostrowski and AR Caggiula

Correlation between locomotor stimulation and the electrophysiological effects of low doses of morphine on substantia nigra dopamine neurons. I. Acute drug administration
J Pharmacol Exp Ther 1991 257: 72-81. [Abstract] [PDF]  

M Kobayashi, H Nakamura, J Kobayashi, and Y Ohizumi

Mechanism of inotropic action of xestoquinone, a novel cardiotonic agent isolated from a sea sponge
J Pharmacol Exp Ther 1991 257: 82-89. [Abstract] [PDF]  

M Kobayashi, A Muroyama, H Nakamura, J Kobayashi, and Y Ohizumi

Xestoquinone, a novel cardiotonic agent activates actomyosin ATPase to enhance contractility of skinned cardiac or skeletal muscle fibers
J Pharmacol Exp Ther 1991 257: 90-94. [Abstract] [PDF]  

JA Saydoff, PA Rittenhouse, LD van de Kar, and MS Brownfield

Enhanced serotonergic transmission stimulates oxytocin secretion in conscious male rats
J Pharmacol Exp Ther 1991 257: 95-99. [Abstract] [PDF]  

RA Yokel, AK Datta, and EG Jackson

Evaluation of potential aluminum chelators in vitro by aluminum solubilization ability, aluminum mobilization from transferrin and the octanol/aqueous distribution of the chelators and their complexes with aluminum
J Pharmacol Exp Ther 1991 257: 100-106. [Abstract] [PDF]  

O Matusak, O Kuchel, and P Hamet

Effect of atrial natriuretic factor and 8-bromo cyclic guanosine 3':5'- monophosphate on [3H]acetylcholine outflow from myenteric-plexus longitudinal muscle of the guinea pig
J Pharmacol Exp Ther 1991 257: 107-113. [Abstract] [PDF]  

E Ongini, S Milani, M Marzanatti, M Trampus, and A Monopoli

Effects of selected beta-adrenergic blocking agents on sleep stages in spontaneously hypertensive rats
J Pharmacol Exp Ther 1991 257: 114-119. [Abstract] [PDF]  

ET Iwamoto

Characterization of the antinociception induced by nicotine in the pedunculopontine tegmental nucleus and the nucleus raphe magnus
J Pharmacol Exp Ther 1991 257: 120-133. [Abstract] [PDF]  

LA Merkel, LM Rivera, DJ Colussi, and MH Perrone

Protein kinase C and vascular smooth muscle contractility: effects of inhibitors and down-regulation
J Pharmacol Exp Ther 1991 257: 134-140. [Abstract] [PDF]  

Y Itzhak, I Stein, SH Zhang, CO Kassim, and D Cristante

Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes
J Pharmacol Exp Ther 1991 257: 141-148. [Abstract] [PDF]  

DA Griffiths, SD Hall, and PP Sokol

Interaction of 3'-azido-3'-deoxythymidine with organic ion transport in rat renal basolateral membrane vesicles
J Pharmacol Exp Ther 1991 257: 149-155. [Abstract] [PDF]  

GJ Grover, J Newburger, PG Sleph, S Dzwonczyk, SC Taylor, SZ Ahmed, and KS Atwal

Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides
J Pharmacol Exp Ther 1991 257: 156-162. [Abstract] [PDF]  

CP Cheng, Y Igarashi, K Pettersson, and WC Little

Effect of felodipine on left ventricular performance in conscious dogs: assessment by left ventricular pressure-volume analysis
J Pharmacol Exp Ther 1991 257: 163-169. [Abstract] [PDF]  

M Pacheco, SR Childers, R Arnold, F Casiano, and SJ Ward

Aminoalkylindoles: actions on specific G-protein-linked receptors
J Pharmacol Exp Ther 1991 257: 170-183. [Abstract] [PDF]  

JJ Pancrazio, MP Viglione, RJ Kleiman, and YI Kim

Verapamil-induced blockade of voltage-activated K+ current in small- cell lung cancer cells
J Pharmacol Exp Ther 1991 257: 184-191. [Abstract] [PDF]  

LS Sorkin, MG Hughes, D Liu, WD Jr Willis, and DJ McAdoo

Release and metabolism of 5-hydroxytryptamine in the cat spinal cord examined with microdialysis
J Pharmacol Exp Ther 1991 257: 192-199. [Abstract] [PDF]  

A Takayama, Y Okazaki, K Fukuda, M Takano, K Inui, and R Hori

Transport of cyclosporin A in kidney epithelial cell line (LLC-PK1)
J Pharmacol Exp Ther 1991 257: 200-204. [Abstract] [PDF]  

LE Brackett and JW Daly

Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms
J Pharmacol Exp Ther 1991 257: 205-213. [Abstract] [PDF]  

G Bittar, HS Friedman, A Dominguez, and V Vorperian

Theophylline produces an adverse effect on myocardial lactate metabolism at a therapeutic serum concentration: an effect blocked by verapamil
J Pharmacol Exp Ther 1991 257: 214-218. [Abstract] [PDF]  

CS Park, PS Doh, CJ Lee, DS Han, RE Carraway, and TB Miller

Cellular mechanism of stimulation of renin secretion by the mercurial diuretic mersalyl
J Pharmacol Exp Ther 1991 257: 219-224. [Abstract] [PDF]  

PE Simson, HE Criswell, KB Johnson, RE Hicks, and GR Breese

Ethanol inhibits NMDA-evoked electrophysiological activity in vivo
J Pharmacol Exp Ther 1991 257: 225-231. [Abstract] [PDF]  

D Ratge, KP Kohse, U Steegmuller, and H Wisser

Distribution of free and conjugated catecholamines between plasma, platelets and erythrocytes: different effects of intravenous and oral catecholamine administrations
J Pharmacol Exp Ther 1991 257: 232-238. [Abstract] [PDF]  

SM Johnson

Nonspecific tolerance in ileal circular muscle-myenteric plexus preparations from morphine-pretreated guinea pigs
J Pharmacol Exp Ther 1991 257: 239-246. [Abstract] [PDF]  

RW Foltin and MW Fischman

Smoked and intravenous cocaine in humans: acute tolerance, cardiovascular and subjective effects
J Pharmacol Exp Ther 1991 257: 247-261. [Abstract] [PDF]  

JF Bowyer, AC Scallet, RR Holson, GW Lipe, W Jr Slikker, and SF Ali

Interactions of MK-801 with glutamate-, glutamine- and methamphetamine- evoked release of [3H]dopamine from striatal slices
J Pharmacol Exp Ther 1991 257: 262-270. [Abstract] [PDF]  

T Nabeshima, K Tohyama, K Murase, S Ishihara, T Kameyama, T Yamasaki, S Hatanaka, H Kojima, T Sakurai, and Y Takasu

Effects of DM-9384, a cyclic derivative of GABA, on amnesia and decreases in GABAA and muscarinic receptors induced by cycloheximide
J Pharmacol Exp Ther 1991 257: 271-275. [Abstract] [PDF]  

R Andriantsitohaina, JC Stoclet, and RD Bukoski

Role of endothelium on the effects of neuropeptide Y in mesenteric resistance arteries of spontaneously hypertensive and Wistar-Kyoto normotensive rats
J Pharmacol Exp Ther 1991 257: 276-281. [Abstract] [PDF]  

MB Abou-Donia, ZH Hu, DM Lapadula, and RP Gupta

Mechanisms of joint neurotoxicity of n-hexane, methyl isobutyl ketone and O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens
J Pharmacol Exp Ther 1991 257: 282-289. [Abstract] [PDF]  

VM Miller, NA Flavahan, and PM Vanhoutte

Pertussis toxin reduces endothelium-dependent and independent responses to alpha-2- adrenergic stimulation in systemic canine arteries and veins
J Pharmacol Exp Ther 1991 257: 290-293. [Abstract] [PDF]  

KS Pang, F 3d Barker, WF Cherry, and CA Goresky

Esterases for enalapril hydrolysis are concentrated in the perihepatic venous region of the rat liver
J Pharmacol Exp Ther 1991 257: 294-301. [Abstract] [PDF]  

JL Banasik, H Hosick, JW Wright, and JW Harding

Endothelin binding in brain of normotensive and spontaneously hypertensive rats
J Pharmacol Exp Ther 1991 257: 302-306. [Abstract] [PDF]  

JP Boni, WH Barr, and BR Martin

Cocaine inhalation in the rat: pharmacokinetics and cardiovascular response
J Pharmacol Exp Ther 1991 257: 307-315. [Abstract] [PDF]  

MR Bleavins, FA de la Iglesia, AE Munson, JA McCay, ML Stern, BA Fuchs, and KL Jr White

Effects of CI-949, a novel antiallergy agent, on immune function of male Fischer 344 rats
J Pharmacol Exp Ther 1991 257: 316-322. [Abstract] [PDF]  

KY Sheff, MA Yorek, and JP Long

Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells
J Pharmacol Exp Ther 1991 257: 323-330. [Abstract] [PDF]  

P Porta, S Aebi, K Summer, and BH Lauterburg

L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human
J Pharmacol Exp Ther 1991 257: 331-334. [Abstract] [PDF]  

CW Murray and A Cowan

Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists
J Pharmacol Exp Ther 1991 257: 335-341. [Abstract] [PDF]  

NA Castle

Selective inhibition of potassium currents in rat ventricle by clofilium and its tertiary homolog
J Pharmacol Exp Ther 1991 257: 342-350. [Abstract] [PDF]  

XZ Wu, JA Bell, CE Spivak, ED London, and TP Su

Electrophysiological and binding studies on intact NCB-20 cells suggest presence of a low affinity sigma receptor
J Pharmacol Exp Ther 1991 257: 351-359. [Abstract] [PDF]  

S Aran and DL Hammond

Antagonism of baclofen-induced antinociception by intrathecal administration of phaclofen or 2-hydroxy-saclofen, but not delta- aminovaleric acid in the rat
J Pharmacol Exp Ther 1991 257: 360-368. [Abstract] [PDF]  

T Shimamura, T Kimura, and S Satoh

Effects of pirenzepine, AF-DX 116 and gallamine on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation: interaction of M1 and M2 receptors with nicotinic receptors
J Pharmacol Exp Ther 1991 257: 369-373. [Abstract] [PDF]  

TL Yue, MM Gleason, JL Gu, PG Lysko, J Hallenbeck, and G Feuerstein

Platelet-activating factor (PAF) receptor-mediated calcium mobilization and phosphoinositide turnover in neurohybrid NG108-15 cells: studies with BN50739, a new PAF antagonist
J Pharmacol Exp Ther 1991 257: 374-381. [Abstract] [PDF]  

PJ Silver, B O'Connor, WR Cumiskey, G Van Aller, LT Hamel, RG Bentley, and ED Pagani

Inhibition of low Km cGMP phosphodiesterases and Ca+(+)-regulated protein kinases and relationship to vasorelaxation by cicletanine
J Pharmacol Exp Ther 1991 257: 382-391. [Abstract] [PDF]  

A Fisher, R Brandeis, I Karton, Z Pittel, D Gurwitz, R Haring, M Sapir, A Levy, and E Heldman

(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease
J Pharmacol Exp Ther 1991 257: 392-403. [Abstract] [PDF]  

S Takeo, R Tanonaka, K Miyake, K Tanonaka, T Taguchi, K Kawakami, M Ono, M Hiramatsu, and K Okano

Naftidrofuryl oxalate improves impaired brain glucose metabolism after microsphere-induced cerebral embolism in rats
J Pharmacol Exp Ther 1991 257: 404-410. [Abstract] [PDF]  

DR Abernethy, LS Kaminsky, and TH Dickinson

Selective inhibition of warfarin metabolism by diltiazem in humans
J Pharmacol Exp Ther 1991 257: 411-415. [Abstract] [PDF]  

RR Ben-Harari, BA Dalton, R Osman, and S Maayani

Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta
J Pharmacol Exp Ther 1991 257: 416-424. [Abstract] [PDF]  

A Dedeoglu and LA Fisher

Central nervous actions of serotonin and a serotonin1A receptor agonist: cardiovascular excitation at low doses
J Pharmacol Exp Ther 1991 257: 425-432. [Abstract] [PDF]  

A Varrault, V Leviel, and J Bockaert

5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists
J Pharmacol Exp Ther 1991 257: 433-438. [Abstract] [PDF]  

G Bravo, J Ghysel-Burton, P Jaumin, and T Godfraind

A comparison of the inotropic effects of dopamine and epinine in human isolated cardiac preparations
J Pharmacol Exp Ther 1991 257: 439-443. [Abstract] [PDF]  

CE Lau, A Imam, F Ma, and JL Falk

Acute effects of cocaine on spontaneous and discriminative motor functions: relation to route of administration and pharmacokinetics
J Pharmacol Exp Ther 1991 257: 444-456. [Abstract] [PDF]  

JL Falk, F Ma, and CE Lau

Chronic oral cocaine self-administration: pharmacokinetics and effects on spontaneous and discriminative motor functions
J Pharmacol Exp Ther 1991 257: 457-465. [Abstract] [PDF]  

A Ezzaher, N el Houda Bouanani, JB Su, L Hittinger, and B Crozatier

Increased negative inotropic effect of calcium-channel blockers in hypertrophied and failing rabbit heart
J Pharmacol Exp Ther 1991 257: 466-471. [Abstract] [PDF]  

JW Mandema, LN Sansom, MC Dios-Vieitez, M Hollander-Jansen, and M Danhof

Pharmacokinetic-pharmacodynamic modeling of the electroencephalographic effects of benzodiazepines. Correlation with receptor binding and anticonvulsant activity
J Pharmacol Exp Ther 1991 257: 472-478. [Abstract] [PDF]  

AE Ahmed, S Jacob, JP Loh, SK Samra, M Nokta, and RB Pollard

Comparative disposition and whole-body autoradiographic distribution of [2-14C]azidothymidine and [2-14C]thymidine in mice
J Pharmacol Exp Ther 1991 257: 479-486. [Abstract] [PDF]  

DM Kerins, M Shuh, S Kunitada, GA Fitzgerald, and DJ Fitzgerald

A prostacyclin analog impairs the response to tissue-type plasminogen activator during coronary thrombolysis: evidence for a pharmacokinetic interaction
J Pharmacol Exp Ther 1991 257: 487-492. [Abstract] [PDF]  

M Soose, W Gwinner, J Grotkamp, W Hansemann, and H Stolte

Altered renal fibronectin excretion in early adriamycin nephrosis of rats
J Pharmacol Exp Ther 1991 257: 493-499. [Abstract] [PDF]  

HA Pretus, HE Ensley, RB McNamee, EL Jones, IW Browder, and DL Williams

Isolation, physicochemical characterization and preclinical efficacy evaluation of soluble scleroglucan
J Pharmacol Exp Ther 1991 257: 500-510. [Abstract] [PDF]  

VF Raczkowski, YM Hernandez, HK Erzouki, TP Abrahams, AK Mandal, P Hamosh, E Friedman, JA Quest, KL Dretchen, and RA Gillis

Cocaine acts in the central nervous system to inhibit sympathetic neural activity
J Pharmacol Exp Ther 1991 257: 511-519. [Abstract] [PDF]  

A Terzic and SM Vogel

On the mechanism of the positive inotropic action of the alpha adrenoceptor agonist, phenylephrine, in isolated rat left atria
J Pharmacol Exp Ther 1991 257: 520-529. [Abstract] [PDF]  

LF Tseng and KA Collins

Different mechanisms mediating tail-flick inhibition induced by beta- endorphin, DAMGO and morphine from ROb and GiA in anesthetized rats
J Pharmacol Exp Ther 1991 257: 530-538. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1991 257: 539. [Abstract] [PDF]  

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