ARTICLES:

JG Granneman and CJ Whitty

CGP 12177A modulates brown fat adenylate cyclase activity by interacting with two distinct receptor sites
J Pharmacol Exp Ther 1991 256: 421-425. [Abstract] [PDF]  

GL Kamatchi and MK Ticku

A functional assay to measure postsynaptic gamma-aminobutyric acidB responses in cultured spinal cord neurons: heterologous regulation of the same K+ channel
J Pharmacol Exp Ther 1991 256: 426-431. [Abstract] [PDF]  

W Loscher and D Honack

Anticonvulsant and behavioral effects of two novel competitive N-methyl- D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine
J Pharmacol Exp Ther 1991 256: 432-440. [Abstract] [PDF]  

GE Boeckxstaens, PA Pelckmans, JJ Bogers, H Bult, JG De Man, L Oosterbosch, AG Herman, and YM Van Maercke

Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus
J Pharmacol Exp Ther 1991 256: 441-447. [Abstract] [PDF]  

JJ Rady, SC Roerig, and JM Fujimoto

Heroin acts on different opioid receptors than morphine in Swiss Webster and ICR mice to produce antinociception
J Pharmacol Exp Ther 1991 256: 448-457. [Abstract] [PDF]  

M Polhuijs, DK Meijer, and GJ Mulder

The fate of diastereomeric glutathione conjugates of alpha- bromoisovalerylurea in blood in the rat in vivo and in the perfused liver. Stereoselectivity in biliary and urinary excretion
J Pharmacol Exp Ther 1991 256: 458-461. [Abstract] [PDF]  

DJ Hupe, ER Pfefferkorn, ND Behrens, and K Peters

L-651,582 inhibition of intracellular parasitic protozoal growth correlates with host-cell directed effects
J Pharmacol Exp Ther 1991 256: 462-467. [Abstract] [PDF]  

NH Lee and EE el-Fakahany

Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes
J Pharmacol Exp Ther 1991 256: 468-479. [Abstract] [PDF]  

D Raeburn and TJ Brown

RP 49356 and cromakalim relax airway smooth muscle in vitro by opening a sulphonylurea-sensitive K+ channel: a comparison with nifedipine
J Pharmacol Exp Ther 1991 256: 480-485. [Abstract] [PDF]  

CJ Chen, S Apparsundaram, and MF Lokhandwala

Intrarenally produced angiotensin II opposes the natriuretic action of the dopamine-1 receptor agonist fenoldopam in rats
J Pharmacol Exp Ther 1991 256: 486-491. [Abstract] [PDF]  

KD Meisheri, MA Swirtz, SS Purohit, LA Cipkus-Dubray, SA Khan, and JJ Oleynek

Characterization of K+ channel-dependent as well as -independent components of pinacidil-induced vasodilation
J Pharmacol Exp Ther 1991 256: 492-499. [Abstract] [PDF]  

J Manzanares, KJ Lookingland, and KE Moore

Kappa opioid receptor-mediated regulation of dopaminergic neurons in the rat brain
J Pharmacol Exp Ther 1991 256: 500-505. [Abstract] [PDF]  

PK Sonsalla, DE Riordan, and RE Heikkila

Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice
J Pharmacol Exp Ther 1991 256: 506-512. [Abstract] [PDF]  

SP Duckles

Reserpine-induced supersensitivity in rat caudal artery: influence of age
J Pharmacol Exp Ther 1991 256: 513-518. [Abstract] [PDF]  

T Massamiri and SP Duckles

Interactions of sigma and phencyclidine receptor ligands with the norepinephrine uptake carrier in both rat brain and rat tail artery
J Pharmacol Exp Ther 1991 256: 519-524. [Abstract] [PDF]  

O Mukaiyama, A Takeuchi, T Kimura, and S Satoh

Effects of pirenzepine and AF-DX 116 on ganglionic transmission in the cardiac sympathetic nerves of the dog: interaction of M1 and M2 receptors with nicotinic receptors
J Pharmacol Exp Ther 1991 256: 525-529. [Abstract] [PDF]  

NR Swerdlow, VA Keith, DL Braff, and MA Geyer

Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat
J Pharmacol Exp Ther 1991 256: 530-536. [Abstract] [PDF]  

KF Heim, G Thomas, and PW Ramwell

Superoxide production in the isolated rabbit aorta and the effect of alloxan, indomethacin and nitrovasodilators
J Pharmacol Exp Ther 1991 256: 537-541. [Abstract] [PDF]  

AS Nies, ML Beckmann, and JG Gerber

Contrasting effects of changes in salt balance on the renovascular response to A1-adenosine receptor stimulation in vivo and in vitro in the rat
J Pharmacol Exp Ther 1991 256: 542-546. [Abstract] [PDF]  

PJ Riviere, SC Farmer, TF Burks, and F Porreca

Prostaglandin E2-induced diarrhea in mice: importance of colonic secretion
J Pharmacol Exp Ther 1991 256: 547-552. [Abstract] [PDF]  

GJ Christ and M Jean-Jacques

Mutual-effect amplification of contractile responses elicited by simultaneous activation of alpha-1 adrenergic and 5-hydroxytryptamine2 receptors in isolated rat aorta
J Pharmacol Exp Ther 1991 256: 553-561. [Abstract] [PDF]  

L Noronha-Blob and JF Kachur

Enantiomers of oxybutynin: in vitro pharmacological characterization at M1, M2 and M3 muscarinic receptors and in vivo effects on urinary bladder contraction, mydriasis and salivary secretion in guinea pigs
J Pharmacol Exp Ther 1991 256: 562-567. [Abstract] [PDF]  

RE Weishaar, RL Panek, TC Major, J Simmerman, ST Rapundalo, and DG Jr Taylor

Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure
J Pharmacol Exp Ther 1991 256: 568-574. [Abstract] [PDF]  

K Lutfy and BC Yoburn

The role of opioid receptor density in morphine tolerance
J Pharmacol Exp Ther 1991 256: 575-580. [Abstract] [PDF]  

E Baldi and MJ Dunn

Endothelin binding and receptor down regulation in rat glomerular mesangial cells
J Pharmacol Exp Ther 1991 256: 581-586. [Abstract] [PDF]  

PA Johnston and ST Kau

Micropuncture evaluation of the site of action of 2-aminomethyl-4-(1,1- dimethylethyl)-6-iodophenol hydrochloride (MK447) in the rat kidney
J Pharmacol Exp Ther 1991 256: 587-591. [Abstract] [PDF]  

J Hauser and S Szabo

Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury
J Pharmacol Exp Ther 1991 256: 592-598. [Abstract] [PDF]  

RN Willette, JP Hieble, and CF Sauermelch

The role of alpha adrenoceptor subtypes in sympathetic control of the acral-cutaneous microcirculation
J Pharmacol Exp Ther 1991 256: 599-605. [Abstract] [PDF]  

E Tibirica, J Feldman, C Mermet, F Gonon, and P Bousquet

An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan
J Pharmacol Exp Ther 1991 256: 606-613. [Abstract] [PDF]  

RG Pendleton, G Gessner, and E Horner

Comparative effects of angiotensin II and angiotensin III in rabbit adrenal and aortic tissues
J Pharmacol Exp Ther 1991 256: 614-620. [Abstract] [PDF]  

JW Hubbard, PG Conway, LC Nordstrom, HB Hartman, Y Lebedinsky, GJ O'Malley, and RW Jr Kosley

Cardiac adenylate cyclase activity, positive chronotropic and inotropic effects of forskolin analogs with either low, medium or high binding site affinity
J Pharmacol Exp Ther 1991 256: 621-627. [Abstract] [PDF]  

LC Wilkes and MR Boarder

Characterization of the endothelin binding site on bovine adrenomedullary chromaffin cells: comparison with vascular smooth muscle cells. Evidence for receptor heterogeneity
J Pharmacol Exp Ther 1991 256: 628-633. [Abstract] [PDF]  

Y Kamisaki, T Hamahashi, C Mita, and T Itoh

D-2 dopamine receptors inhibit release of aspartate and glutamate in rat retina
J Pharmacol Exp Ther 1991 256: 634-638. [Abstract] [PDF]  

NJ Lodge, RB Cohen, CN Havens, and TJ Colatsky

The effects of the putative potassium channel activator WAY-120,491 on 86Rb efflux from the rabbit aorta
J Pharmacol Exp Ther 1991 256: 639-644. [Abstract] [PDF]  

TE Nelson, M Lin, and P Volpe

Evidence for intraluminal Ca++ regulatory site defect in sarcoplasmic reticulum from malignant hyperthermia pig muscle
J Pharmacol Exp Ther 1991 256: 645-649. [Abstract] [PDF]  

S Shibanoki, SB Weinberger, D Beniston, KA Nudelman, G Schulteis, EL Bennett, MR Rosenzweig, K Ishikawa, and JL Jr Martinez

Hydrolysis of [Leu]enkephalin by chick plasma in vitro
J Pharmacol Exp Ther 1991 256: 650-655. [Abstract] [PDF]  

JG Hensler, GA Ordway, C Gambarana, P Areso, and A Frazer

Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol
J Pharmacol Exp Ther 1991 256: 656-664. [Abstract] [PDF]  

FA Redegeld, GA Hofman, PG van de Loo, AS Koster, and J Noordhoek

Nephrotoxicity of the glutathione conjugate of menadione (2-methyl-1, 4- naphthoquinone) in the isolated perfused rat kidney. Role of metabolism by gamma-glutamyltranspeptidase and probenecid-sensitive transport
J Pharmacol Exp Ther 1991 256: 665-669. [Abstract] [PDF]  

LJ Janssen and EE Daniel

Classification of postjunctional beta adrenoceptors mediating relaxation of canine bronchi
J Pharmacol Exp Ther 1991 256: 670-676. [Abstract] [PDF]  

M Kuhn, A Otten, JC Frolich, and U Forstermann

Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells
J Pharmacol Exp Ther 1991 256: 677-682. [Abstract] [PDF]  

H Shirahase, H Usui, H Shimaji, K Kurahashi, and M Fujiwara

Endothelium-independent and endothelium-dependent contractions mediated by P2X- and P2Y-purinoceptors in canine basilar arteries
J Pharmacol Exp Ther 1991 256: 683-688. [Abstract] [PDF]  

L Mei, J Lai, HI Yamamura, and WR Roeske

Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82)
J Pharmacol Exp Ther 1991 256: 689-694. [Abstract] [PDF]  

VL Lucaites, LG Mendelsohn, NR Mason, and ML Cohen

CCK-8, CCK-4 and gastrin-induced contractions in guinea pig ileum: evidence for differential release of acetylcholine and substance P by CCK-A and CCK-B receptors
J Pharmacol Exp Ther 1991 256: 695-703. [Abstract] [PDF]  

JE Shaffer, F Lee, S Thomson, BJ Han, JP Cooke, and J Loscalzo

The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs
J Pharmacol Exp Ther 1991 256: 704-709. [Abstract] [PDF]  

PY Law, DS Hom, and HH Loh

Effect of chronic D-Ala,2 D-Leu5-enkephalin or pertussis toxin treatment on the high-affinity state of delta opioid receptor in neuroblastoma x glioma NG108-15 hybrid cells
J Pharmacol Exp Ther 1991 256: 710-716. [Abstract] [PDF]  

PT Peachell, LM Lichtenstein, and RP Schleimer

Differential regulation of human basophil and lung mast cell function by adenosine [published erratum appears in J Pharmacol Exp Ther 1991 Apr;257(1):539]
J Pharmacol Exp Ther 1991 256: 717-726. [Abstract] [PDF]  

F Dorje, J Wess, G Lambrecht, R Tacke, E Mutschler, and MR Brann

Antagonist binding profiles of five cloned human muscarinic receptor subtypes
J Pharmacol Exp Ther 1991 256: 727-733. [Abstract] [PDF]  

JV Frnka, AS Chang, and DM Lam

Pharmacological characteristics of high-affinity serotonin uptake systems established through gene transfer
J Pharmacol Exp Ther 1991 256: 734-740. [Abstract] [PDF]  

PJ Bushnell, SS Padilla, T Ward, CN Pope, and VB Olszyk

Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate
J Pharmacol Exp Ther 1991 256: 741-750. [Abstract] [PDF]  

SX Ma, JP Long, JR Flynn, PA Leonard, and JG Cannon

Dopaminergic structure-activity relationships of 2-aminoindans and cardiovascular action and dopaminergic activity of 4-hydroxy, 5-methyl, 2-di-n-propylaminoindan (RD-211)
J Pharmacol Exp Ther 1991 256: 751-756. [Abstract] [PDF]  

JB Pracyk, SE Lappi, and TA Slotkin

Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney
J Pharmacol Exp Ther 1991 256: 757-766. [Abstract] [PDF]  

C Legrand, V Vivat, C Rigolot, and JP Maltier

Selective distribution of alpha-1 and beta adrenoceptors in pregnant rat uterus visualized by autoradiography
J Pharmacol Exp Ther 1991 256: 767-772. [Abstract] [PDF]  

T Kobayashi, H Hasegawa, E Kaneko, and A Ichiyama

Gastrointestinal serotonin: depletion due to tetrahydrobiopterin deficiency induced by 2,4-diamino-6-hydroxypyrimidine administration
J Pharmacol Exp Ther 1991 256: 773-779. [Abstract] [PDF]  

PJ Simpson, JA Schelm, and GF Smith

Therapeutic defibrination with ancrod does not protect canine myocardium from reperfusion injury
J Pharmacol Exp Ther 1991 256: 780-786. [Abstract] [PDF]  

MJ Owens, DL Knight, JC Ritchie, and CB Nemeroff

The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)- 2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain
J Pharmacol Exp Ther 1991 256: 787-794. [Abstract] [PDF]  

MJ Owens, DL Knight, JC Ritchie, and CB Nemeroff

The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)- 2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration
J Pharmacol Exp Ther 1991 256: 795-800. [Abstract] [PDF]  

SK Wilson

Peripheral alpha-1 and alpha-2 adrenergic receptors in three models of hypertension in rats: an in vitro autoradiography study
J Pharmacol Exp Ther 1991 256: 801-810. [Abstract] [PDF]  

S Subramaniam and P McGonigle

Quantitative autoradiographic characterization of the binding of (+)-5- methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK- 801) in rat brain: regional effects of polyamines
J Pharmacol Exp Ther 1991 256: 811-819. [Abstract] [PDF]  

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