ARTICLES:

RK Zalups, RM Gelein, and E Cernichiari

DMPS as a rescue agent for the nephropathy induced by mercuric chloride
J Pharmacol Exp Ther 1991 256: 1-10. [Abstract] [PDF]  

K Miura, T Yukimura, Y Yamashita, T Shimmen, M Okumura, S Yamanaka, M Imanishi, and K Yamamoto

Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins
J Pharmacol Exp Ther 1991 256: 11-17. [Abstract] [PDF]  

M Kimura, I Kimura, T Kondoh, and H Tsuneki

Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle
J Pharmacol Exp Ther 1991 256: 18-23. [Abstract] [PDF]  

I Kimura, H Tsuneki, T Kondoh, and M Kimura

Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle
J Pharmacol Exp Ther 1991 256: 24-28. [Abstract] [PDF]  

KG Mugridge, M Perretti, C Becherucci, and L Parente

Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase
J Pharmacol Exp Ther 1991 256: 29-37. [Abstract] [PDF]  

K Ishii, B Chang, JF Jr Kerwin, FL Wagenaar, ZJ Huang, and F Murad

Formation of endothelium-derived relaxing factor in porcine kidney epithelial LLC-PK1 cells: an intra- and intercellular messenger for activation of soluble guanylate cyclase
J Pharmacol Exp Ther 1991 256: 38-43. [Abstract] [PDF]  

LG Jr Harsing and ES Vizi

Evidence that two stereochemically different alpha-2 adrenoceptors modulate norepinephrine release in rat cerebral cortex
J Pharmacol Exp Ther 1991 256: 44-49. [Abstract] [PDF]  

NA Flavahan, H Shimokawa, and PM Vanhoutte

Inhibition of endothelium-dependent relaxations by phorbol myristate acetate in canine coronary arteries: role of a pertussis toxin- sensitive G-protein
J Pharmacol Exp Ther 1991 256: 50-55. [Abstract] [PDF]  

NJ Brown, J Porter, D Ryder, and RA Branch

Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine
J Pharmacol Exp Ther 1991 256: 56-61. [Abstract] [PDF]  

SG Holtzman, S Mante, and KP Minneman

Role of adenosine receptors in caffeine tolerance
J Pharmacol Exp Ther 1991 256: 62-68. [Abstract] [PDF]  

YF Huang, RN Upton, WB Runciman, and LE Mather

Insight into interstitial drug disposition: lymph concentrations of lidocaine, procainamide and meperidine in the hindquarters of unanesthetized and anesthetized sheep
J Pharmacol Exp Ther 1991 256: 69-75. [Abstract] [PDF]  

T Nakazawa, Y Furuya, T Kaneko, and K Yamatsu

Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice
J Pharmacol Exp Ther 1991 256: 76-81. [Abstract] [PDF]  

AG Meehan and DL Kreulen

Electrophysiological studies on the interaction of 5-hydroxytryptamine with sympathetic transmission in the guinea pig inferior mesenteric artery and ganglion
J Pharmacol Exp Ther 1991 256: 82-87. [Abstract] [PDF]  

M Raiteri, G Bonanno, E Fedele, G Fontana, and A Gemignani

gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex
J Pharmacol Exp Ther 1991 256: 88-93. [Abstract] [PDF]  

RA Hahn, BR MacDonald, PJ Simpson, L Wang, RD Towner, PP Ho, M Goodwin, AP Breau, T Suarez, and ED Mihelich

Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium
J Pharmacol Exp Ther 1991 256: 94-102. [Abstract] [PDF]  

RJ Secrest, VL Lucaites, LG Mendelsohn, and ML Cohen

Protein kinase C translocation in rat stomach fundus: effects of serotonin, carbamylcholine and phorbol dibutyrate
J Pharmacol Exp Ther 1991 256: 103-109. [Abstract] [PDF]  

A Roca-Cusachs, DJ DiPette, and GA Nickols

Regional and systemic hemodynamic effects of parathyroid hormone- related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure
J Pharmacol Exp Ther 1991 256: 110-118. [Abstract] [PDF]  

EE Brown, JM Finlay, JT Wong, G Damsma, and HC Fibiger

Behavioral and neurochemical interactions between cocaine and buprenorphine: implications for the pharmacotherapy of cocaine abuse
J Pharmacol Exp Ther 1991 256: 119-126. [Abstract] [PDF]  

A Garcia-Pascual, G Costa, M Isla, E Jimenez, and A Garcia-Sacristan

Potassium-induced contraction in the lamb proximal urethra: involvement of norepinephrine and different calcium entry pathways
J Pharmacol Exp Ther 1991 256: 127-134. [Abstract] [PDF]  

XB Wang, N Sato, MA Greer, SE Greer, and S McAdams

Quinidine inhibits prolactin secretion induced by thyrotropin-releasing hormone, high medium potassium or hyposmolarity in GH4C1 cells
J Pharmacol Exp Ther 1991 256: 135-140. [Abstract] [PDF]  

CC Shieh, MF Petrini, TM Dwyer, and JM Farley

Concentration-dependence of acetylcholine-induced changes in calcium and tension in swine trachealis
J Pharmacol Exp Ther 1991 256: 141-148. [Abstract] [PDF]  

SS Negus, MJ Picker, and LA Dykstra

Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey
J Pharmacol Exp Ther 1991 256: 149-158. [Abstract] [PDF]  

JM Spitsbergen and WD Atchison

Voltage clamp analysis reveals multiple populations of quanta released at neuromuscular junctions of rats treated with 2,4-dithiobiuret
J Pharmacol Exp Ther 1991 256: 159-163. [Abstract] [PDF]  

FM Lai, T Tanikella, and P Cervoni

Characterization of serotonin receptors in isolated rat intramyocardial coronary artery
J Pharmacol Exp Ther 1991 256: 164-168. [Abstract] [PDF]  

K Takahashi and N Akaike

Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons
J Pharmacol Exp Ther 1991 256: 169-175. [Abstract] [PDF]  

NA Robinson, JG Pace, CF Matson, GA Miura, and WB Lawrence

Tissue distribution, excretion and hepatic biotransformation of microcystin-LR in mice
J Pharmacol Exp Ther 1991 256: 176-182. [Abstract] [PDF]  

SP Han, AJ Trapani, KF Fok, TC Westfall, and MM Knuepfer

A comparison of the hemodynamic effects of endothelin-1 and sarafotoxin S6b in conscious rats
J Pharmacol Exp Ther 1991 256: 183-188. [Abstract] [PDF]  

DA Katzka, JC Reynolds, AD King, and S Cohen

Low dose verapamil and nitroprusside distinguish tonic from cholinergic- induced contractions in in vivo feline lower esophageal sphincter
J Pharmacol Exp Ther 1991 256: 189-193. [Abstract] [PDF]  

MJ Van Diest, TJ Verbeuren, and AG Herman

15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase
J Pharmacol Exp Ther 1991 256: 194-203. [Abstract] [PDF]  

B Borowsky and CM Kuhn

Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation
J Pharmacol Exp Ther 1991 256: 204-210. [Abstract] [PDF]  

DB Vaupel and EJ Cone

Pharmacodynamic and pharmacokinetic actions of ketocyclazocine enantiomers in the dog: absence of sigma- or phencyclidine-like activity
J Pharmacol Exp Ther 1991 256: 211-221. [Abstract] [PDF]  

MI Steinberg, SA Wiest, KM Zimmerman, PJ Ertel, KG Bemis, and DW Robertson

Chiral recognition of pinacidil and its 3-pyridyl isomer by canine cardiac and smooth muscle: antagonism by sulfonylureas
J Pharmacol Exp Ther 1991 256: 222-229. [Abstract] [PDF]  

CJ Schmidt, VL Taylor, GM Abbate, and TR Nieduzak

5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4- methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa
J Pharmacol Exp Ther 1991 256: 230-235. [Abstract] [PDF]  

PC Levesque and WD Atchison

Disruption of brain mitochondrial calcium sequestration by methylmercury
J Pharmacol Exp Ther 1991 256: 236-242. [Abstract] [PDF]  

M Floreani and F Carpenedo

Modifications of cardiac contractility by redox cycling alkylating and mixed redox cycling/alkylating quinones
J Pharmacol Exp Ther 1991 256: 243-248. [Abstract] [PDF]  

JA Bauer and HL Fung

Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure
J Pharmacol Exp Ther 1991 256: 249-254. [Abstract] [PDF]  

CC Chao, TW Molitor, G Gekker, MP Murtaugh, and PK Peterson

Cocaine-mediated suppression of superoxide production by human peripheral blood mononuclear cells
J Pharmacol Exp Ther 1991 256: 255-258. [Abstract] [PDF]  

CK Kellogg, RJ Primus, and D Bitran

Sexually dimorphic influence of prenatal exposure to diazepam on behavioral responses to environmental challenge and on gamma- aminobutyric acid (GABA)-stimulated chloride uptake in the brain
J Pharmacol Exp Ther 1991 256: 259-265. [Abstract] [PDF]  

C Moummi, GW Gullikson, MB Grisham, and TS Gaginella

Differential effects of reactive oxygen metabolites on neurally stimulated and nonstimulated guinea pig ileum
J Pharmacol Exp Ther 1991 256: 266-271. [Abstract] [PDF]  

N Yoshida, A Mizumoto, Y Iwanaga, and Z Itoh

Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs
J Pharmacol Exp Ther 1991 256: 272-278. [Abstract] [PDF]  

SF Flaim, MM Gleason, A Hedberg, RP Shank, JR McCullough, A Gill, BP Damiano, MD Brannan, and JR Carson

Structurally novel antihypertensive compound, McN-5691, is a calcium channel blocker in vascular smooth muscle
J Pharmacol Exp Ther 1991 256: 279-288. [Abstract] [PDF]  

CW Xie and DV Lewis

Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse
J Pharmacol Exp Ther 1991 256: 289-296. [Abstract] [PDF]  

SS Navran, G Allain, HF Garcia, JC Allen, and CL Seidel

Serotonin-induced Na+/K+ pump stimulation in vascular smooth muscle cells. Evidence for coupling to multiple receptor mechanisms
J Pharmacol Exp Ther 1991 256: 297-303. [Abstract] [PDF]  

DJ Pettibone, BV Clineschmidt, EV Lis, DR Reiss, JA Totaro, CJ Woyden, MG Bock, RM Freidinger, RD Tung, and DF Veber

In vitro pharmacological profile of a novel structural class of oxytocin antagonists
J Pharmacol Exp Ther 1991 256: 304-308. [Abstract] [PDF]  

T Wang and YL Chan

The role of phosphoinositide turnover in mediating the biphasic effect of angiotensin II on renal tubular transport
J Pharmacol Exp Ther 1991 256: 309-317. [Abstract] [PDF]  

M Gwilt, JE Arrowsmith, KJ Blackburn, RA Burges, PE Cross, HW Dalrymple, and AJ Higgins

UK-68,798: a novel, potent and highly selective class III antiarrhythmic agent which blocks potassium channels in cardiac cells
J Pharmacol Exp Ther 1991 256: 318-324. [Abstract] [PDF]  

G Zuanetti and PB Corr

Antiarrhythmic efficacy of a new class III agent, UK-68,798, during chronic myocardial infarction: evaluation using three-dimensional mapping
J Pharmacol Exp Ther 1991 256: 325-334. [Abstract] [PDF]  

CR Albrightson-Winslow, B Brickson, DP Brooks, WM Bryan, N Caldwell, LB Kinter, ML Moore, P Nambi, FL Stassen, and WF Huffman

Vasopressin antidiuretic agonist and antagonist activity in dogs: structural and stereochemical relationship between bridge and carboxyl terminus
J Pharmacol Exp Ther 1991 256: 335-340. [Abstract] [PDF]  

P Blandina, J Goldfarb, J Walcott, and JP Green

Serotonergic modulation of the release of endogenous norepinephrine from rat hypothalamic slices
J Pharmacol Exp Ther 1991 256: 341-347. [Abstract] [PDF]  

J Ichikawa and HY Meltzer

Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens
J Pharmacol Exp Ther 1991 256: 348-357. [Abstract] [PDF]  

JA Miller, NL Velayo, RC Dage, and D Rampe

High affinity [3H]glibenclamide binding sites in rat neuronal and cardiac tissue: localization and developmental characteristics
J Pharmacol Exp Ther 1991 256: 358-364. [Abstract] [PDF]  

X Nair, J Quigley, KM Tramposch, FI Carroll, AH Lewin, and I Kiss

BMY 30047: a novel topically active retinoid with low local and systemic toxicity
J Pharmacol Exp Ther 1991 256: 365-370. [Abstract] [PDF]  

K Fujino, S Nakaya, T Wakatsuki, Y Miyoshi, Y Nakaya, H Mori, and I Inoue

Effects of nitroglycerin on ATP-induced Ca(++)-mobilization, Ca(++)- activated K channels and contraction of cultured smooth muscle cells of porcine coronary artery
J Pharmacol Exp Ther 1991 256: 371-377. [Abstract] [PDF]  

T Nabeshima, A Katoh, H Ishimaru, Y Yoneda, K Ogita, K Murase, H Ohtsuka, K Inari, T Fukuta, and T Kameyama

Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice
J Pharmacol Exp Ther 1991 256: 378-384. [Abstract] [PDF]  

E Chavez, C Zazueta, A Osornio, JA Holguin, and ME Miranda

Protective behavior of captopril on Hg(++)-induced toxicity on kidney mitochondria. In vivo and in vitro experiments
J Pharmacol Exp Ther 1991 256: 385-390. [Abstract] [PDF]  

S Kanekal, C Plopper, D Morin, and A Buckpitt

Metabolism and cytotoxicity of naphthalene oxide in the isolated perfused mouse lung
J Pharmacol Exp Ther 1991 256: 391-401. [Abstract] [PDF]  

K Kato, PS Puttfarcken, WE Lyons, and JT Coyle

Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures
J Pharmacol Exp Ther 1991 256: 402-411. [Abstract] [PDF]  

LJ Dahm, AE Schultze, and RA Roth

An antibody to neutrophils attenuates alpha-naphthylisothiocyanate- induced liver injury
J Pharmacol Exp Ther 1991 256: 412-420. [Abstract] [PDF]  

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