ARTICLES:

GJ Trachte, CM Ferrario, and MC Khosla

Selective blockade of angiotensin responses in the rabbit isolated vas deferens by angiotensin receptor antagonists
J Pharmacol Exp Ther 1990 255: 929-934. [Abstract] [PDF]  

H Jaeschke

Glutathione disulfide formation and oxidant stress during acetaminophen- induced hepatotoxicity in mice in vivo: the protective effect of allopurinol
J Pharmacol Exp Ther 1990 255: 935-941. [Abstract] [PDF]  

L Rakotoarisoa, I Sayet, C Mironneau, and J Mironneau

Selective modulation by membrane potential of desmethoxyverapamil binding to calcium channels in rat portal vein
J Pharmacol Exp Ther 1990 255: 942-947. [Abstract] [PDF]  

P Lebrun, MH Antoine, V Devreux, M Hermann, and A Herchuelz

Paradoxical inhibitory effect of cromakalim on 86Rb outflow from pancreatic islet cells
J Pharmacol Exp Ther 1990 255: 948-954. [Abstract] [PDF]  

E Puil, H el-Beheiry, and KG Baimbridge

Anesthetic effects on glutamate-stimulated increase in intraneuronal calcium
J Pharmacol Exp Ther 1990 255: 955-961. [Abstract] [PDF]  

HO Heuer, J Casals-Stenzel, G Muacevic, and KH Weber

Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor
J Pharmacol Exp Ther 1990 255: 962-968. [Abstract] [PDF]  

JB Pritchard

Rat renal cortical slices demonstrate p-aminohippurate/glutarate exchange and sodium/glutarate coupled p-aminohippurate transport
J Pharmacol Exp Ther 1990 255: 969-975. [Abstract] [PDF]  

PU Dubuc and CM Peterson

Ineffectiveness of parenteral fluoxetine or RU-486 to alter long-term food intake, body weight or body composition of genetically obese mice
J Pharmacol Exp Ther 1990 255: 976-979. [Abstract] [PDF]  

Y Hamagishi, S Murata, H Kamei, T Oki, O Adachi, and M Ameyama

New biological properties of pyrroloquinoline quinone and its related compounds: inhibition of chemiluminescence, lipid peroxidation and rat paw edema
J Pharmacol Exp Ther 1990 255: 980-985. [Abstract] [PDF]  

WH Griffith and JA Sim

Comparison of 4-aminopyridine and tetrahydroaminoacridine on basal forebrain neurons
J Pharmacol Exp Ther 1990 255: 986-993. [Abstract] [PDF]  

VB Schini, ZS Katusic, and PM Vanhoutte

Neurohypophyseal peptides and tachykinins stimulate the production of cyclic GMP in cultured porcine aortic endothelial cells
J Pharmacol Exp Ther 1990 255: 994-1000. [Abstract] [PDF]  

IJ Reynolds

Arcaine uncovers dual interactions of polyamines with the N-methyl-D- aspartate receptor
J Pharmacol Exp Ther 1990 255: 1001-1007. [Abstract] [PDF]  

RE Howell

Multiple mechanisms of xanthine actions on airway reactivity
J Pharmacol Exp Ther 1990 255: 1008-1014. [Abstract] [PDF]  

TE Raya, RG Gay, and S Goldman

Selective vasopressin inhibition in rats with heart failure decreases afterload and results in venodilatation
J Pharmacol Exp Ther 1990 255: 1015-1020. [Abstract] [PDF]  

S Seiler, CL Brassard, AJ Arnold, NA Meanwell, JS Fleming, and SL Jr Keely

Octimibate inhibition of platelet aggregation: stimulation of adenylate cyclase through prostacyclin receptor activation
J Pharmacol Exp Ther 1990 255: 1021-1026. [Abstract] [PDF]  

JU Adams, CA Paronis, and SG Holtzman

Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine
J Pharmacol Exp Ther 1990 255: 1027-1032. [Abstract] [PDF]  

T Okano, H Maegawa, K Inui, and R Hori

Interaction of ofloxacin with organic cation transport system in rat renal brush-border membranes
J Pharmacol Exp Ther 1990 255: 1033-1037. [Abstract] [PDF]  

NA Castle

Bupivacaine inhibits the transient outward K+ current but not the inward rectifier in rat ventricular myocytes
J Pharmacol Exp Ther 1990 255: 1038-1046. [Abstract] [PDF]  

J Zawilska and PM Iuvone

Alpha-2 adrenergic activity of bromocriptine and quinpirole in chicken pineal gland. Effects on melatonin synthesis and [3H]rauwolscine binding
J Pharmacol Exp Ther 1990 255: 1047-1052. [Abstract] [PDF]  

DC Eikenburg

Effects of chronic norepinephrine administration on sympathetic neurotransmission in the isolated perfused rat kidney
J Pharmacol Exp Ther 1990 255: 1053-1059. [Abstract] [PDF]  

AI Sacaan and KM Johnson

Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate- induced hippocampal [3H]norepinephrine release
J Pharmacol Exp Ther 1990 255: 1060-1063. [Abstract] [PDF]  

XM Yang, AL Gorman, and AJ Dunn

The involvement of central noradrenergic systems and corticotropin- releasing factor in defensive-withdrawal behavior in rats
J Pharmacol Exp Ther 1990 255: 1064-1070. [Abstract] [PDF]  

HE Shannon, KG Bemis, JC Hendrix, and JS Ward

Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats
J Pharmacol Exp Ther 1990 255: 1071-1077. [Abstract] [PDF]  

Y Isobe, H Nagai, M Muramatsu, H Aihara, and S Otomo

Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats
J Pharmacol Exp Ther 1990 255: 1078-1082. [Abstract] [PDF]  

WM Armstead, R Mirro, DW Busija, and CW Leffler

Prostanoids modulate opioid cerebrovascular responses in newborn pigs
J Pharmacol Exp Ther 1990 255: 1083-1089. [Abstract] [PDF]  

Y Itoh, R Oishi, M Nishibori, and K Saeki

In vivo measurement of noradrenaline and 3,4- dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism
J Pharmacol Exp Ther 1990 255: 1090-1097. [Abstract] [PDF]  

R Oberlender and DE Nichols

(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity
J Pharmacol Exp Ther 1990 255: 1098-1106. [Abstract] [PDF]  

MH Ossipov, S Harris, P Lloyd, and E Messineo

An isobolographic analysis of the antinociceptive effect of systemically and intrathecally administered combinations of clonidine and opiates
J Pharmacol Exp Ther 1990 255: 1107-1116. [Abstract] [PDF]  

PJ Pauwels, HP Van Assouw, L Peeters, and JE Leysen

Neurotoxic action of veratridine in rat brain neuronal cultures: mechanism of neuroprotection by Ca++ antagonists nonselective for slow Ca++ channels
J Pharmacol Exp Ther 1990 255: 1117-1122. [Abstract] [PDF]  

RR Griffiths, SM Evans, SJ Heishman, KL Preston, CA Sannerud, B Wolf, and PP Woodson

Low-dose caffeine physical dependence in humans
J Pharmacol Exp Ther 1990 255: 1123-1132. [Abstract] [PDF]  

EH Jr Ellinwood, AM Nikaido, SK Gupta, DG Heatherly, and JK Nishita

Comparison of central nervous system and peripheral pharmacodynamics to atropine pharmacokinetics
J Pharmacol Exp Ther 1990 255: 1133-1139. [Abstract] [PDF]  

CC Felder, P Dieter, J Kinsella, K Tamura, RY Kanterman, and J Axelrod

A transfected m5 muscarinic acetylcholine receptor stimulates phospholipase A2 by inducing both calcium influx and activation of protein kinase C
J Pharmacol Exp Ther 1990 255: 1140-1147. [Abstract] [PDF]  

FJ Ehlert and LP Tran

Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain
J Pharmacol Exp Ther 1990 255: 1148-1157. [Abstract] [PDF]  

CT Dourish, MF O'Neill, LW Schaffer, PK Siegl, and SD Iversen

The cholecystokinin receptor antagonist devazepide enhances morphine- induced analgesia but not morphine-induced respiratory depression in the squirrel monkey
J Pharmacol Exp Ther 1990 255: 1158-1165. [Abstract] [PDF]  

DM Pollock and TJ Opgenorth

Beneficial effect of the atrial natriuretic factor analog A68828 in postischemic acute renal failure
J Pharmacol Exp Ther 1990 255: 1166-1169. [Abstract] [PDF]  

C Prior, JF Fiekers, F Henderson, J Dempster, IG Marshall, and RL Parsons

End-plate ion channel block produced by lincosamide antibiotics and their chemical analogs
J Pharmacol Exp Ther 1990 255: 1170-1176. [Abstract] [PDF]  

MA Czuba, DJ Morgan, MS Ching, GW Mihaly, KJ Hardy, and RA Smallwood

Ontogeny of fetal renal organic cation excretion: a study with cimetidine and ranitidine during the latter half of gestation in the pregnant ewe
J Pharmacol Exp Ther 1990 255: 1177-1182. [Abstract] [PDF]  

KW Jr Hunter, AA Brimfield, AT Knower, JA Powell, and GZ Feuerstein

Reversal of intracellular toxicity of the trichothecene mycotoxin T-2 with monoclonal antibody
J Pharmacol Exp Ther 1990 255: 1183-1187. [Abstract] [PDF]  

MP Gupta, N Makino, S Takeo, M Kaneko, and NS Dhalla

Cardiac sarcolemma as a possible site of action of caffeine in rat heart
J Pharmacol Exp Ther 1990 255: 1188-1194. [Abstract] [PDF]  

C Brodie and SR Sampson

Effects of ethanol on voltage-sensitive Na-channels in cultured skeletal muscle: up-regulation as a result of chronic treatment
J Pharmacol Exp Ther 1990 255: 1195-1201. [Abstract] [PDF]  

MS Dar

Central adenosinergic system involvement in ethanol-induced motor incoordination in mice
J Pharmacol Exp Ther 1990 255: 1202-1209. [Abstract] [PDF]  

T Kanayama, Y Kimura, K Iseki, Y Hayashi, Y Tamao, and S Mizogami

Antithrombotic effects of KP-10614, a novel and stable prostacyclin (PGI2) analog
J Pharmacol Exp Ther 1990 255: 1210-1217. [Abstract] [PDF]  

I Takahashi, E Kobayashi, H Nakano, C Murakata, H Saitoh, K Suzuki, and T Tamaoki

Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C
J Pharmacol Exp Ther 1990 255: 1218-1221. [Abstract] [PDF]  

FW Lee, T Salmonson, CH Metzler, and LZ Benet

Pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its two dinitrate metabolites in conscious dogs
J Pharmacol Exp Ther 1990 255: 1222-1229. [Abstract] [PDF]  

SJ Ward, D Mastriani, F Casiano, and R Arnold

Pravadoline: profile in isolated tissue preparations
J Pharmacol Exp Ther 1990 255: 1230-1239. [Abstract] [PDF]  

A Poling, J Cleary, K Berens, and T Thompson

Neuroleptics and learning: effects of haloperidol, molindone, mesoridazine and thioridazine on the behavior of pigeons under a repeated acquisition procedure
J Pharmacol Exp Ther 1990 255: 1240-1245. [Abstract] [PDF]  

SM Evans, FR Funderburk, and RR Griffiths

Zolpidem and triazolam in humans: behavioral and subjective effects and abuse liability
J Pharmacol Exp Ther 1990 255: 1246-1255. [Abstract] [PDF]  

EA Kowaluk and HL Fung

Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols
J Pharmacol Exp Ther 1990 255: 1256-1264. [Abstract] [PDF]  

DM Burnett, JF Bowyer, JM Masserano, and NR Zahniser

Effect of aging on alpha-1 adrenergic stimulation of phosphoinositide hydrolysis in various regions of rat brain
J Pharmacol Exp Ther 1990 255: 1265-1270. [Abstract] [PDF]  

CP France, Y Lu, and JH Woods

Interactions between N-methyl-D-aspartate and CGS 19755 administered intramuscularly and intracerebroventricularly in pigeons
J Pharmacol Exp Ther 1990 255: 1271-1277. [Abstract] [PDF]  

RJ Knapp, LK Vaughn, SN Fang, CL Bogert, MS Yamamura, VJ Hruby, and HI Yamamura

A new, highly selective CCK-B receptor radioligand ([3H][N-methyl- Nle28,31]CCK26-33): evidence for CCK-B receptor heterogeneity
J Pharmacol Exp Ther 1990 255: 1278-1286. [Abstract] [PDF]  

DM Ignar and CM Kuhn

Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat
J Pharmacol Exp Ther 1990 255: 1287-1295. [Abstract] [PDF]  

MA Wallace and E Claro

Comparison of serotoninergic to muscarinic cholinergic stimulation of phosphoinositide-specific phospholipase C in rat brain cortical membranes
J Pharmacol Exp Ther 1990 255: 1296-1300. [Abstract] [PDF]  

DD Schoepp, PL Ornstein, JD Leander, D Lodge, CR Salhoff, S Zeman, and DM Zimmerman

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action
J Pharmacol Exp Ther 1990 255: 1301-1308. [Abstract] [PDF]  

MH Fernandes and P Soares-da-Silva

Effects of MAO-A and MAO-B selective inhibitors Ro 41-1049 and Ro 19- 6327 on the deamination of newly formed dopamine in the rat kidney
J Pharmacol Exp Ther 1990 255: 1309-1313. [Abstract] [PDF]  

JJ Beutler, HA Koomans, JA Bijlsma, and EJ Dorhout Mees

Renal actions of theophylline and atrial natriuretic peptide in humans: a comparison by means of clearance studies
J Pharmacol Exp Ther 1990 255: 1314-1319. [Abstract] [PDF]  

MC Dyson, JA Bellan, RK Minkes, RC Beckerman, MJ Wegmann, P Braquet, DB McNamara, and PJ Kadowitz

Influence of SK&F 95587 and BN 50730 on bronchoconstrictor responses in the cat
J Pharmacol Exp Ther 1990 255: 1320-1327. [Abstract] [PDF]  

JG Wettstein, ES Teeple, and WH Morse

Respiratory effects of benzodiazepine-related drugs in awake rhesus monkeys
J Pharmacol Exp Ther 1990 255: 1328-1334. [Abstract] [PDF]  

LE Schechter, FJ Bolanos, H Gozlan, L Lanfumey, S Haj-Dahmane, AM Laporte, CM Fattaccini, and M Hamon

Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies
J Pharmacol Exp Ther 1990 255: 1335-1347. [Abstract] [PDF]  

OA Fasehun, SS Gross, LE Rubin, EA Jaffe, OW Griffith, and R Levi

L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor
J Pharmacol Exp Ther 1990 255: 1348-1353. [Abstract] [PDF]  

X Pascaud, JP Defaux, C Roze, and JL Junien

Effect of selective sigma ligands on duodenal alkaline secretion in the rat
J Pharmacol Exp Ther 1990 255: 1354-1359. [Abstract] [PDF]  

DG Soergel, F Gusovsky, T Yasumoto, and JW Daly

Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown
J Pharmacol Exp Ther 1990 255: 1360-1365. [Abstract] [PDF]  

LF Jones and RL Tackett

Chronic cocaine treatment enhances the responsiveness of the left anterior descending coronary artery and the femoral artery to vasoactive substances
J Pharmacol Exp Ther 1990 255: 1366-1370. [Abstract] [PDF]  

B Fromenty, C Fisch, G Labbe, C Degott, D Deschamps, A Berson, P Letteron, and D Pessayre

Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice
J Pharmacol Exp Ther 1990 255: 1371-1376. [Abstract] [PDF]  

B Fromenty, C Fisch, A Berson, P Letteron, D Larrey, and D Pessayre

Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II
J Pharmacol Exp Ther 1990 255: 1377-1384. [Abstract] [PDF]  

S Imaoka, K Enomoto, Y Oda, A Asada, M Fujimori, T Shimada, S Fujita, FP Guengerich, and Y Funae

Lidocaine metabolism by human cytochrome P-450s purified from hepatic microsomes: comparison of those with rat hepatic cytochrome P-450s
J Pharmacol Exp Ther 1990 255: 1385-1391. [Abstract] [PDF]  

PJ Robinson, HC Cheng, CK Black, CJ Schmidt, T Kariya, WD Jones, and RC Dage

MDL 27,032 [4-propyl-5-(4-pyridinyl)-2(3H)-oxazolone], an active site- directed inhibitor of protein kinase C and cyclic AMP-dependent protein kinase that relaxes vascular smooth muscle
J Pharmacol Exp Ther 1990 255: 1392-1398. [Abstract] [PDF]  

JJ Anderson and JA DiMicco

Effect of local inhibition of gamma-aminobutyric acid uptake in the dorsomedial hypothalamus on extracellular levels of gamma-aminobutyric acid and on stress-induced tachycardia: a study using microdialysis
J Pharmacol Exp Ther 1990 255: 1399-1407. [Abstract] [PDF]  

GM Kalabis and PG Wells

Biphasic modulation of acetaminophen bioactivation and hepatotoxicity by pretreatment with the interferon inducer polyinosinic-polycytidylic acid
J Pharmacol Exp Ther 1990 255: 1408-1419. [Abstract] [PDF]  

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