ARTICLES:

KM Hull and TJ Maher

L-tyrosine potentiates the anorexia induced by mixed-acting sympathomimetic drugs in hyperphagic rats
J Pharmacol Exp Ther 1990 255: 403-409. [Abstract] [PDF]  

HU Bryant and RE Roudebush

Suppressive effects of morphine pellet implants on in vivo parameters of immune function
J Pharmacol Exp Ther 1990 255: 410-414. [Abstract] [PDF]  

RP Garay, JP Labaune, D Mesangeau, C Nazaret, T Imbert, and G Moinet

CRE 10904 [2-(p-fluorophenoxy), 1-(o-hydroxyphenyl)-ethane]: a new diuretic and antihypertensive drug acting by in vivo sulfation
J Pharmacol Exp Ther 1990 255: 415-422. [Abstract] [PDF]  

SP Han, L Naes, and TC Westfall

Calcitonin gene-related peptide is the endogenous mediator of nonadrenergic-noncholinergic vasodilation in rat mesentery
J Pharmacol Exp Ther 1990 255: 423-428. [Abstract] [PDF]  

C Ripoll, WJ Lederer, and CG Nichols

Modulation of ATP-sensitive K+ channel activity and contractile behavior in mammalian ventricle by the potassium channel openers cromakalim and RP49356
J Pharmacol Exp Ther 1990 255: 429-435. [Abstract] [PDF]  

PP Sokol

Effect of DQ-2556, a new cephalosporin, on organic ion transport in renal plasma membrane vesicles from the dog, rabbit and rat
J Pharmacol Exp Ther 1990 255: 436-441. [Abstract] [PDF]  

F Zavala, V Taupin, and B Descamps-Latscha

In vivo treatment with benzodiazepines inhibits murine phagocyte oxidative metabolism and production of interleukin 1, tumor necrosis factor and interleukin-6
J Pharmacol Exp Ther 1990 255: 442-450. [Abstract] [PDF]  

AI Faden, R Shirane, LH Chang, TL James, M Lemke, and PR Weinstein

Opiate-receptor antagonist improves metabolic recovery and limits neurochemical alterations associated with reperfusion after global brain ischemia in rats
J Pharmacol Exp Ther 1990 255: 451-458. [Abstract] [PDF]  

ER Jacobs and TE DeCoursey

Mechanisms of potassium channel block in rat alveolar epithelial cells
J Pharmacol Exp Ther 1990 255: 459-472. [Abstract] [PDF]  

MY Farhat, PW Ramwell, and G Thomas

Endothelium-mediated effects of N-substituted arginines on the isolated perfused rat kidney
J Pharmacol Exp Ther 1990 255: 473-477. [Abstract] [PDF]  

CJ Schmidt, GM Abbate, CK Black, and VL Taylor

Selective 5-hydroxytryptamine2 receptor antagonists protect against the neurotoxicity of methylenedioxymethamphetamine in rats
J Pharmacol Exp Ther 1990 255: 478-483. [Abstract] [PDF]  

T Shimizu, T Kawabata, and M Nakamura

Protective effect of a novel calcium blocker, S-312-d, on ischemic acute renal failure in rat
J Pharmacol Exp Ther 1990 255: 484-490. [Abstract] [PDF]  

PG Cox, WM Moons, FG Russel, and CA van Ginneken

Renal disposition and effects of naproxen and its l-enantiomer in the isolated perfused rat kidney
J Pharmacol Exp Ther 1990 255: 491-496. [Abstract] [PDF]  

JG Drewett, RJ Ziegler, and GJ Trachte

Neuromodulatory effects of atrial natriuretic factor are independent of guanylate cyclase in adrenergic neuronal pheochromocytoma cells
J Pharmacol Exp Ther 1990 255: 497-503. [Abstract] [PDF]  

Y Kumagai, T Todaka, and S Toki

A new metabolic pathway of morphine: in vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig
J Pharmacol Exp Ther 1990 255: 504-510. [Abstract] [PDF]  

DR Haubrich, SJ Ward, E Baizman, MR Bell, J Bradford, R Ferrari, M Miller, M Perrone, AK Pierson, and JK Saelens

Pharmacology of pravadoline: a new analgesic agent
J Pharmacol Exp Ther 1990 255: 511-522. [Abstract] [PDF]  

M Feria, C Alvarez, J Dominguez, A Sanchez, and J Boada

Naloxone potentiation of cardiovascular responses to sympathomimetic amines in the rat
J Pharmacol Exp Ther 1990 255: 523-528. [Abstract] [PDF]  

E Freneaux, B Fromenty, A Berson, G Labbe, C Degott, P Letteron, D Larrey, and D Pessayre

Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids
J Pharmacol Exp Ther 1990 255: 529-535. [Abstract] [PDF]  

AL Giordano, B Nock, and TJ Cicero

Antagonist-induced up-regulation of the putative epsilon opioid receptor in rat brain: comparison with kappa, mu and delta opioid receptors
J Pharmacol Exp Ther 1990 255: 536-540. [Abstract] [PDF]  

W Loscher, D Honack, R Scherkl, A Hashem, and HH Frey

Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs
J Pharmacol Exp Ther 1990 255: 541-548. [Abstract] [PDF]  

HE Shannon and SC Peters

A comparison of the effects of cholinergic and dopaminergic agents on scopolamine-induced hyperactivity in mice
J Pharmacol Exp Ther 1990 255: 549-553. [Abstract] [PDF]  

J Hidalgo, JS Garvey, and A Armario

On the metallothionein, glutathione and cysteine relationship in rat liver
J Pharmacol Exp Ther 1990 255: 554-564. [Abstract] [PDF]  

RC Falcone and D Aharony

Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents
J Pharmacol Exp Ther 1990 255: 565-571. [Abstract] [PDF]  

DJ Fretland, D Widomski, BS Tsai, JM Zemaitis, S Levin, SW Djuric, RL Shone, and TS Gaginella

Effect of the leukotriene B4 receptor antagonist SC-41930 on colonic inflammation in rat, guinea pig and rabbit
J Pharmacol Exp Ther 1990 255: 572-576. [Abstract] [PDF]  

RE Galinsky, DH Johnson, RE Kane, and MR Franklin

Effect of aging on hepatic biotransformation in female Fischer 344 rats: changes in sulfotransferase activities are consistent with known gender-related changes in pituitary growth hormone secretion in aging animals
J Pharmacol Exp Ther 1990 255: 577-583. [Abstract] [PDF]  

PC Wong, SD Hart, AM Zaspel, AT Chiu, RJ Ardecky, RD Smith, and PB Timmermans

Functional studies of nonpeptide angiotensin II receptor subtype- specific ligands: DuP 753 (AII-1) and PD123177 (AII-2)
J Pharmacol Exp Ther 1990 255: 584-592. [Abstract] [PDF]  

P Polster, B Christophe, M Van Damme, A Houlliche, and P Chatelain

SR 33557, a novel calcium entry blocker. I. In vitro isolated tissue studies
J Pharmacol Exp Ther 1990 255: 593-599. [Abstract] [PDF]  

P Nokin, M Clinet, P Beaufort, L Meysmans, R Laruel, and P Chatelain

SR 33557, a novel calcium entry blocker. II. Interactions with 1,4- dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes
J Pharmacol Exp Ther 1990 255: 600-607. [Abstract] [PDF]  

AI Faden, SW Yum, M Lemke, and R Vink

Effects of TRH-analog treatment on tissue cations, phospholipids and energy metabolism after spinal cord injury
J Pharmacol Exp Ther 1990 255: 608-614. [Abstract] [PDF]  

MT Whittico, YA Gang, and KM Giacomini

Cimetidine transport in isolated brush border membrane vesicles from bovine choroid plexus
J Pharmacol Exp Ther 1990 255: 615-623. [Abstract] [PDF]  

BF Thomas, DR Compton, and BR Martin

Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency
J Pharmacol Exp Ther 1990 255: 624-630. [Abstract] [PDF]  

TA Heming, CG Vanoye, and A Bidani

Dipyridamole inhibition of HCO3(-)-Cl- exchange in human erythrocytes
J Pharmacol Exp Ther 1990 255: 631-635. [Abstract] [PDF]  

JA Qi, WD Bowen, HI Mosberg, RB Rothman, and F Porreca

Opioid agonist and antagonist antinociceptive properties of [D- Ala2,Leu5,Cys6]enkephalin: selective actions at the deltanoncomplexed site
J Pharmacol Exp Ther 1990 255: 636-641. [Abstract] [PDF]  

J Turgeon, HN Pavlou, W Wong, C Funck-Brentano, and DM Roden

Genetically determined steady-state interaction between encainide and quinidine in patients with arrhythmias
J Pharmacol Exp Ther 1990 255: 642-649. [Abstract] [PDF]  

SA Keitz, R Osman, WP Clarke, J Goldfarb, and S Maayani

Functional interactions in smooth muscle: kinetic characterization of the relaxation and desensitization responses to a beta adrenergic agonist in the rabbit aorta
J Pharmacol Exp Ther 1990 255: 650-656. [Abstract] [PDF]  

M Maitre, V Hechler, P Vayer, S Gobaille, CD Cash, M Schmitt, and JJ Bourguignon

A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties
J Pharmacol Exp Ther 1990 255: 657-663. [Abstract] [PDF]  

JB Cheng, JS Pillar, MJ Conklyn, R Breslow, JT Shirley, and HJ Showell

Evidence that peptidoleukotriene is a prerequisite for antigen- dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs
J Pharmacol Exp Ther 1990 255: 664-671. [Abstract] [PDF]  

NA Boughattas, F Levi, C Fournier, B Hecquet, G Lemaigre, A Roulon, G Mathe, and A Reinberg

Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice
J Pharmacol Exp Ther 1990 255: 672-679. [Abstract] [PDF]  

Y Nasa, K Ichihara, and Y Abiko

Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart
J Pharmacol Exp Ther 1990 255: 680-689. [Abstract] [PDF]  

GK Lloyd, G Danielou, and F Thuret

The activity of zolpidem and other hypnotics within the gamma- aminobutyric acid (GABAA) receptor supramolecular complex, as determined by 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding to rat cerebral cortex membranes
J Pharmacol Exp Ther 1990 255: 690-696. [Abstract] [PDF]  

TR Jones, L Charette, ML Garcia, and GJ Kaczorowski

Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor
J Pharmacol Exp Ther 1990 255: 697-706. [Abstract] [PDF]  

TJ Cicero, ML Adams, L O'Connor, B Nock, ER Meyer, and D Wozniak

Influence of chronic alcohol administration on representative indices of puberty and sexual maturation in male rats and the development of their progeny
J Pharmacol Exp Ther 1990 255: 707-715. [Abstract] [PDF]  

T Okaniwa, H Echizen, T Ishizaki, M Kasao, and T Iizuka

Pharmacodynamic characterization of posture-related diuretic and saluretic responses to furosemide in humans
J Pharmacol Exp Ther 1990 255: 716-723. [Abstract] [PDF]  

H Tanaka and T Tokiwa

Pharmacokinetics of recombinant human granulocyte colony-stimulating factor studied in the rat by a sandwich enzyme-linked immunosorbent assay
J Pharmacol Exp Ther 1990 255: 724-729. [Abstract] [PDF]  

KC Kirby, ML Stitzer, and SJ Heishman

Acute opioid physical dependence in humans: effect of varying the morphine-naloxone interval II
J Pharmacol Exp Ther 1990 255: 730-737. [Abstract] [PDF]  

CD Jeck and MR Rosen

Use-dependent effects of lidocaine in neonatal and adult ventricular myocardium
J Pharmacol Exp Ther 1990 255: 738-743. [Abstract] [PDF]  

WR Martin, JW Sloan, and E Wala

Precipitated abstinence in orally dosed benzodiazepine-dependent dogs
J Pharmacol Exp Ther 1990 255: 744-755. [Abstract] [PDF]  

JE Bleasdale, NR Thakur, RS Gremban, GL Bundy, FA Fitzpatrick, RJ Smith, and S Bunting

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils
J Pharmacol Exp Ther 1990 255: 756-768. [Abstract] [PDF]  

D Paul, JA Levison, DH Howard, CG Pick, EF Hahn, and GW Pasternak

Naloxone benzoylhydrazone (NalBzoH) analgesia
J Pharmacol Exp Ther 1990 255: 769-774. [Abstract] [PDF]  

KM Merchant, LG Bush, JW Gibb, and GR Hanson

Neurotensin-dopamine interactions in the substantia nigra of the rat brain
J Pharmacol Exp Ther 1990 255: 775-780. [Abstract] [PDF]  

YN Kwok, C McIntosh, and J Brown

Augmentation of release of gastric somatostatin-like immunoreactivity by adenosine, adenosine triphosphate and their analogs
J Pharmacol Exp Ther 1990 255: 781-788. [Abstract] [PDF]  

T Nabeshima, K Tohyama, K Ichihara, and T Kameyama

Effects of benzodiazepines on passive avoidance response and latent learning in mice: relationship to benzodiazepine receptors and the cholinergic neuronal system
J Pharmacol Exp Ther 1990 255: 789-794. [Abstract] [PDF]  

CG Parsons and A Herz

Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress
J Pharmacol Exp Ther 1990 255: 795-802. [Abstract] [PDF]  

L Ahtee, LM Attila, and KR Carlson

Augmentation of morphine-induced changes in brain monoamine metabolism after chronic naltrexone treatment
J Pharmacol Exp Ther 1990 255: 803-808. [Abstract] [PDF]  

PC Chang, K Szemeredi, E Grossman, IJ Kopin, and DS Goldstein

Fate of tritiated 6-fluorodopamine in rats: a false neurotransmitter for positron emission tomographic imaging of sympathetic innervation and function
J Pharmacol Exp Ther 1990 255: 809-817. [Abstract] [PDF]  

K Masuzawa, M Asano, T Matsuda, Y Imaizumi, and M Watanabe

Possible involvement of ATP-sensitive K+ channels in the relaxant response of dog middle cerebral artery to cromakalim
J Pharmacol Exp Ther 1990 255: 818-825. [Abstract] [PDF]  

R Kawai, Y Sawada, M Channing, B Dunn, AH Newman, KC Rice, and RG Blasberg

Kinetic analysis of the opiate antagonist cyclofoxy in rat brain: simultaneous infusion of active and inactive enantiomers
J Pharmacol Exp Ther 1990 255: 826-835. [Abstract] [PDF]  

JF Giudicelli, CD la Rochelle, and A Berdeaux

Effects of cromakalim and pinacidil on large epicardial and small coronary arteries in conscious dogs
J Pharmacol Exp Ther 1990 255: 836-842. [Abstract] [PDF]  

NM Appel, WM Mitchell, RK Garlick, RA Glennon, M Teitler, and EB De Souza

Autoradiographic characterization of (+-)-1-(2,5-dimethoxy-4-[125I] iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain
J Pharmacol Exp Ther 1990 255: 843-857. [Abstract] [PDF]  

D Beauchamp, G Laurent, P Maldague, S Abid, BK Kishore, and PM Tulkens

Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid
J Pharmacol Exp Ther 1990 255: 858-866. [Abstract] [PDF]  

BK Kishore, Z Kallay, P Lambricht, G Laurent, and PM Tulkens

Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro
J Pharmacol Exp Ther 1990 255: 867-874. [Abstract] [PDF]  

BK Kishore, P Lambricht, G Laurent, P Maldague, R Wagner, and PM Tulkens

Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids
J Pharmacol Exp Ther 1990 255: 875-885. [Abstract] [PDF]  

WP Schiemann, JM Walther, and IL Buxton

On the ability of endogenous adenosine to regulate purine nucleoside receptor binding of antagonists in smooth muscle membranes
J Pharmacol Exp Ther 1990 255: 886-892. [Abstract] [PDF]  

WM Pardridge, D Triguero, J Buciak, and J Yang

Evaluation of cationized rat albumin as a potential blood-brain barrier drug transport vector
J Pharmacol Exp Ther 1990 255: 893-899. [Abstract] [PDF]  

C Alzheimer and G ten Bruggencate

Nonopioid actions of the kappa-opioid receptor agonists, U 50488H and U 69593 on electrophysiologic properties of hippocampal CA3 neurons in vitro
J Pharmacol Exp Ther 1990 255: 900-905. [Abstract] [PDF]  

H Hara and K Kogure

Prevention of hippocampus neuronal damage in ischemic gerbils by a novel lipid peroxidation inhibitor (quinazoline derivative)
J Pharmacol Exp Ther 1990 255: 906-913. [Abstract] [PDF]  

BA Sabel, P Dominiak, W Hauser, MJ During, and A Freese

Levodopa delivery from controlled-release polymer matrix: delivery of more than 600 days in vitro and 225 days of elevated plasma levels after subcutaneous implantation in rats
J Pharmacol Exp Ther 1990 255: 914-922. [Abstract] [PDF]  

J Szolcsanyi, A Szallasi, Z Szallasi, F Joo, and PM Blumberg

Resiniferatoxin: an ultrapotent selective modulator of capsaicin- sensitive primary afferent neurons
J Pharmacol Exp Ther 1990 255: 923-928. [Abstract] [PDF]  

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