ARTICLES:

G Iacono and M Vassalle

On the mechanism of the different sensitivity of Purkinje and myocardial fibers to strophanthidin
J Pharmacol Exp Ther 1990 253: 1-12. [Abstract] [PDF]  

FJ Ehlert, FM Delen, SH Yun, and HA Liem

The interaction of amitriptyline, doxepin, imipramine and their N- methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart
J Pharmacol Exp Ther 1990 253: 13-19. [Abstract] [PDF]  

KM Boje and HL Fung

Endothelial nitric oxide generating enzyme(s) in the bovine aorta: subcellular location and metabolic characterization
J Pharmacol Exp Ther 1990 253: 20-26. [Abstract] [PDF]  

MJ Wiester, JS Tepper, MF Weber, and MG Menache

Histamine and methacholine aerosol bronchial challenge in awake guinea pigs
J Pharmacol Exp Ther 1990 253: 27-33. [Abstract] [PDF]  

R Sabra, K Takahashi, RA Branch, and KF Badr

Mechanisms of amphotericin B-induced reduction of the glomerular filtration rate: a micropuncture study
J Pharmacol Exp Ther 1990 253: 34-37. [Abstract] [PDF]  

J Peris, SJ Boyson, WA Cass, P Curella, LP Dwoskin, G Larson, LH Lin, RP Yasuda, and NR Zahniser

Persistence of neurochemical changes in dopamine systems after repeated cocaine administration
J Pharmacol Exp Ther 1990 253: 38-44. [Abstract] [PDF]  

TH Lin and JH Lin

Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats
J Pharmacol Exp Ther 1990 253: 45-50. [Abstract] [PDF]  

RJ Lukas

Heterogeneity of high-affinity nicotinic [3H]acetylcholine binding sites
J Pharmacol Exp Ther 1990 253: 51-57. [Abstract] [PDF]  

RA Hahn, BR MacDonald, PJ Simpson, BD Potts, and CJ Parli

Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size
J Pharmacol Exp Ther 1990 253: 58-66. [Abstract] [PDF]  

K Nishino, YF Su, CS Wong, WD Watkins, and KJ Chang

Dissociation of mu opioid tolerance from receptor down-regulation in rat spinal cord
J Pharmacol Exp Ther 1990 253: 67-72. [Abstract] [PDF]  

M Iscan and MD Maines

Differential regulation of heme and drug metabolism in rat testis and prostate: response to cis-platinum and human chorionic gonadotropin
J Pharmacol Exp Ther 1990 253: 73-79. [Abstract] [PDF]  

GJ Trachte

Pharmacological differentiation of angiotensin effects in the rabbit isolated vas deferens with dithiothreitol and pertussis toxin
J Pharmacol Exp Ther 1990 253: 80-84. [Abstract] [PDF]  

WN Shaw, CH Mitch, JD Leander, and DM Zimmerman

Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat
J Pharmacol Exp Ther 1990 253: 85-89. [Abstract] [PDF]  

M Mistry and A Nasjletti

Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats
J Pharmacol Exp Ther 1990 253: 90-94. [Abstract] [PDF]  

BS Givens and GR Breese

Electrophysiological evidence that ethanol alters function of medial septal area without affecting lateral septal function
J Pharmacol Exp Ther 1990 253: 95-103. [Abstract] [PDF]  

R Zaczek, G Battaglia, S Culp, NM Appel, JF Contrera, and EB De Souza

Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data
J Pharmacol Exp Ther 1990 253: 104-112. [Abstract] [PDF]  

BD Anderson, BL Hoesterey, DC Baker, and RE Galinsky

Uptake kinetics of 2',3'-dideoxyinosine into brain and cerebrospinal fluid of rats: intravenous infusion studies
J Pharmacol Exp Ther 1990 253: 113-118. [Abstract] [PDF]  

DP Brooks, LC Contino, W Trizna, RM Edwards, EH Ohlstein, and HA Solleveld

Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal ablation
J Pharmacol Exp Ther 1990 253: 119-123. [Abstract] [PDF]  

T Massamiri and SP Duckles

Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses
J Pharmacol Exp Ther 1990 253: 124-129. [Abstract] [PDF]  

JJ Grigg and EG Anderson

Competitive and noncompetitive N-methyl-D-aspartate antagonists modify hypoxia-induced membrane potential changes and protect rat hippocampal slices from functional failure: a quantitative comparison
J Pharmacol Exp Ther 1990 253: 130-135. [Abstract] [PDF]  

BI Ghanayem, JM Sanders, AM Clark, J Bailer, and HB Matthews

Effects of dose, age, inhibition of metabolism and elimination on the toxicokinetics of 2-butoxyethanol and its metabolites
J Pharmacol Exp Ther 1990 253: 136-143. [Abstract] [PDF]  

RJ Sheldon, PJ Riviere, ME Malarchik, HI Moseberg, TF Burks, and F Porreca

Opioid regulation of mucosal ion transport in the mouse isolated jejunum
J Pharmacol Exp Ther 1990 253: 144-151. [Abstract] [PDF]  

RF Kirby and AK Johnson

Effects of sympathetic activation on plasma renin activity in the developing rat
J Pharmacol Exp Ther 1990 253: 152-157. [Abstract] [PDF]  

DL Barringer and RD Bunag

Age-dependent baroreflex attenuation by centrally infused verapamil in rats
J Pharmacol Exp Ther 1990 253: 158-164. [Abstract] [PDF]  

HM Vargas and B Ringdahl

Centrally active antimuscarinic analogs of oxotremorine selectively block physostigmine-induced hypertension, but not peripheral muscarinic vasodepression
J Pharmacol Exp Ther 1990 253: 165-170. [Abstract] [PDF]  

U del Balzo, I Sakuma, and R Levi

Cardiac dysfunction caused by recombinant human C5A anaphylatoxin: mediation by histamine, adenosine and cyclooxygenase arachidonate metabolites
J Pharmacol Exp Ther 1990 253: 171-179. [Abstract] [PDF]  

WR Rebagay and RW Caldwell

Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside
J Pharmacol Exp Ther 1990 253: 180-184. [Abstract] [PDF]  

RK Hoover and ML Toews

Activation of protein kinase C inhibits internalization and downregulation of muscarinic receptors in 1321N1 human astrocytoma cells
J Pharmacol Exp Ther 1990 253: 185-191. [Abstract] [PDF]  

MW Church, EL Abel, BA Dintcheff, and C Matyjasik

Maternal age and blood alcohol concentration in the pregnant Long-Evans rat
J Pharmacol Exp Ther 1990 253: 192-199. [Abstract] [PDF]  

S Chakder and S Rattan

[Tyr0]-calcitonin gene-related peptide 28-37 (rat) as a putative antagonist of calcitonin gene-related peptide responses on opossum internal anal sphincter smooth muscle
J Pharmacol Exp Ther 1990 253: 200-206. [Abstract] [PDF]  

T Nishimiya, HB Daniell, JG Webb, J Oatis, T Walle, TE Gaffney, and PV Halushka

Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats
J Pharmacol Exp Ther 1990 253: 207-213. [Abstract] [PDF]  

V Simonneaux, LC Murrin, and M Ebadi

Characterization of D1 dopamine receptors in the bovine pineal gland with [3H]SCH 23390
J Pharmacol Exp Ther 1990 253: 214-220. [Abstract] [PDF]  

MT Nakada, JM Stadel, and ST Crooke

Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts
J Pharmacol Exp Ther 1990 253: 221-229. [Abstract] [PDF]  

BJ Aungst, JA Blake, NJ Rogers, and BA Dusak

Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent
J Pharmacol Exp Ther 1990 253: 230-236. [Abstract] [PDF]  

NK Mello, JH Mendelson, S Palmieri, BW Lex, and SK Teoh

Operant acquisition of alcohol by women
J Pharmacol Exp Ther 1990 253: 237-245. [Abstract] [PDF]  

F Amenta, A Ricci, and JA Vega

Pharmacological characterization of rat renal medulla dopamine- sensitive cyclic adenosine monophosphate generating system
J Pharmacol Exp Ther 1990 253: 246-249. [Abstract] [PDF]  

Y Hattori, H Nakaya, M Endou, and M Kanno

Inotropic, electrophysiological and biochemical responses to histamine in rabbit papillary muscles: evidence for coexistence of H1- and H2- receptors
J Pharmacol Exp Ther 1990 253: 250-256. [Abstract] [PDF]  

C Eva, SR Gamalero, E Genazzani, and E Costa

Molecular mechanisms of homologous desensitization and internalization of muscarinic receptors in primary cultures of neonatal corticostriatal neurons
J Pharmacol Exp Ther 1990 253: 257-265. [Abstract] [PDF]  

RL Kline and PF Mercer

Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation
J Pharmacol Exp Ther 1990 253: 266-271. [Abstract] [PDF]  

R Tabrizchi and CR Triggle

Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin
J Pharmacol Exp Ther 1990 253: 272-276. [Abstract] [PDF]  

FT van Amsterdam, NC Punt, M Haas, and J Zaagsma

Calcium antagonists show two modes of protection in ischemic heart failure
J Pharmacol Exp Ther 1990 253: 277-283. [Abstract] [PDF]  

M Joels, CM Pennartz, H Sijbesma, and J Schipper

Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus
J Pharmacol Exp Ther 1990 253: 284-289. [Abstract] [PDF]  

FL Christofi, TJ McDonald, and MA Cook

Adenosine receptors are coupled negatively to release of tachykinin(s) from enteric nerve endings
J Pharmacol Exp Ther 1990 253: 290-295. [Abstract] [PDF]  

M Clergue, B Riou, and Y Lecarpentier

Inotropic and lusitropic effects of chlorpromazine on rat left ventricular papillary muscle
J Pharmacol Exp Ther 1990 253: 296-304. [Abstract] [PDF]  

S Urien, R Zini, M Lemaire, and JP Tillement

Assessment of cyclosporine A interactions with human plasma lipoproteins in vitro and in vivo in the rat
J Pharmacol Exp Ther 1990 253: 305-309. [Abstract] [PDF]  

R Micheletti and A Schiavone

Functional determination of McN-A-343 affinity for M1 muscarinic receptors
J Pharmacol Exp Ther 1990 253: 310-314. [Abstract] [PDF]  

A Tsuji, T Terasaki, I Tamai, and K Takeda

In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver
J Pharmacol Exp Ther 1990 253: 315-320. [Abstract] [PDF]  

B Ferrier, M Martin, and G Baverel

Effect of lithium on renal transport and utilization of alpha- ketoglutarate in the rat
J Pharmacol Exp Ther 1990 253: 321-327. [Abstract] [PDF]  

A Lopez-Farre, F Bernabeu, D Gomez-Garre, S Ramon y Cajal, P Braquet, and JM Lopez- Novoa

Platelet-activating factor antagonists treatment protects against postischemic acute renal failure in rats
J Pharmacol Exp Ther 1990 253: 328-333. [Abstract] [PDF]  

DN Stephens, HH Schneider, W Kehr, JS Andrews, KJ Rettig, L Turski, R Schmiechen, JD Turner, LH Jensen, and EN Petersen

Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors
J Pharmacol Exp Ther 1990 253: 334-343. [Abstract] [PDF]  

L Turski, DN Stephens, LH Jensen, EN Petersen, BS Meldrum, S Patel, JB Hansen, W Loscher, HH Schneider, and R Schmiechen

Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio
J Pharmacol Exp Ther 1990 253: 344-352. [Abstract] [PDF]  

M Nayebpour, M Talajic, W Jing, and S Nattel

Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs
J Pharmacol Exp Ther 1990 253: 353-361. [Abstract] [PDF]  

FH Noormohamed, WR McNabb, and AF Lant

Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment
J Pharmacol Exp Ther 1990 253: 362-368. [Abstract] [PDF]  

S Fujita, M Chiba, M Ohta, K Kitani, and T Suzuki

Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats
J Pharmacol Exp Ther 1990 253: 369-374. [Abstract] [PDF]  

MJ Stevens and RF Moulds

Alpha adrenoceptor activation and postreceptor contractile mechanisms in the human digital artery
J Pharmacol Exp Ther 1990 253: 375-380. [Abstract] [PDF]  

J Black, L Diment, C Armour, L Alouan, and P Johnson

Distribution of substance P receptors in rabbit airways, functional and autoradiographic studies
J Pharmacol Exp Ther 1990 253: 381-386. [Abstract] [PDF]  

I de Waziers, PH Cugnenc, CS Yang, JP Leroux, and PH Beaune

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
J Pharmacol Exp Ther 1990 253: 387-394. [Abstract] [PDF]  

MG Lacey, P Calabresi, and RA North

Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors
J Pharmacol Exp Ther 1990 253: 395-400. [Abstract] [PDF]  

AK Louie, ES Bass, J Zhan, PY Law, and HH Loh

Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells
J Pharmacol Exp Ther 1990 253: 401-407. [Abstract] [PDF]  

P Ernsberger, R Giuliano, RN Willette, and DJ Reis

Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla
J Pharmacol Exp Ther 1990 253: 408-418. [Abstract] [PDF]  

AN Schoffelmeer, YH Yao, TL Gioannini, JM Hiller, D Ofri, BP Roques, and EJ Simon

Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex
J Pharmacol Exp Ther 1990 253: 419-426. [Abstract] [PDF]  

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