ARTICLES:

D Roy and WR Snodgrass

Covalent binding of phenytoin to protein and modulation of phenytoin metabolism by thiols in A/J mouse liver microsomes
J Pharmacol Exp Ther 1990 252: 895-900. [Abstract] [PDF]  

HN Bhargava and A Gulati

Modification of brain and spinal cord dopamine D1 receptors labeled with [3H]SCH 23390 after morphine withdrawal from tolerant and physically dependent rats
J Pharmacol Exp Ther 1990 252: 901-907. [Abstract] [PDF]  

GD Hoke, HY Cheng, CK Mirabelli, and GF Rush

Mechanism of inhibition of rat liver mitochondrial respiration by oxmetidine, an H2-receptor antagonist
J Pharmacol Exp Ther 1990 252: 908-914. [Abstract] [PDF]  

EE Reynolds and LL Mok

Role of thromboxane A2/prostaglandin H2 receptor in the vasoconstrictor response of rat aorta to endothelin
J Pharmacol Exp Ther 1990 252: 915-921. [Abstract] [PDF]  

WR Tracey, J Linden, MJ Peach, and RA Johns

Comparison of spectrophotometric and biological assays for nitric oxide (NO) and endothelium-derived relaxing factor (EDRF): nonspecificity of the diazotization reaction for NO and failure to detect EDRF
J Pharmacol Exp Ther 1990 252: 922-928. [Abstract] [PDF]  

RD Page and T Yorio

Prostaglandin F2 alpha inhibits acidification in H(+)-secreting epithelia
J Pharmacol Exp Ther 1990 252: 929-933. [Abstract] [PDF]  

TH Kelly, RW Foltin, AJ Rose, MW Fischman, and JV Brady

Smoked marijuana effects on tobacco cigarette smoking behavior
J Pharmacol Exp Ther 1990 252: 934-944. [Abstract] [PDF]  

RM Craft and LA Dykstra

Differential cross-tolerance to opioids in squirrel monkeys responding under a shock titration schedule
J Pharmacol Exp Ther 1990 252: 945-952. [Abstract] [PDF]  

PM Beardsley, BA Hayes, and RL Balster

The self-administration of MK-801 can depend upon drug-reinforcement history, and its discriminative stimulus properties are phencyclidine- like in rhesus monkeys
J Pharmacol Exp Ther 1990 252: 953-959. [Abstract] [PDF]  

RW Foltin

Differential development of tolerance to the effects of d-amphetamine and fenfluramine on food intake in baboons
J Pharmacol Exp Ther 1990 252: 960-969. [Abstract] [PDF]  

RR Griffiths, SM Evans, SJ Heishman, KL Preston, CA Sannerud, B Wolf, and PP Woodson

Low-dose caffeine discrimination in humans
J Pharmacol Exp Ther 1990 252: 970-978. [Abstract] [PDF]  

SG Oakes, JJ Schlager, KS Santone, RT Abraham, and G Powis

Doxorubicin blocks the increase in intracellular Ca++, part of a second messenger system in N1E-115 murine neuroblastoma cells
J Pharmacol Exp Ther 1990 252: 979-983. [Abstract] [PDF]  

E Sanders-Bush and M Breeding

Serotonin1c receptor reserve in choroid plexus masks receptor subsensitivity
J Pharmacol Exp Ther 1990 252: 984-988. [Abstract] [PDF]  

SY Tam and RH Roth

Modulation of mesoprefrontal dopamine neurons by central benzodiazepine receptors. I. Pharmacological characterization
J Pharmacol Exp Ther 1990 252: 989-996. [Abstract] [PDF]  

IA Paul, GE Duncan, C Kuhn, RA Mueller, JS Hong, and GR Breese

Neural adaptation in imipramine-treated rats processed in forced swim test: assessment of time course, handling, rat strain and amine uptake
J Pharmacol Exp Ther 1990 252: 997-1005. [Abstract] [PDF]  

JA Qi, JS Heyman, RJ Sheldon, RJ Koslo, and F Porreca

Mu antagonist and kappa agonist properties of beta-funaltrexamine (beta- FNA) in vivo: long-lasting spinal analgesia in mice
J Pharmacol Exp Ther 1990 252: 1006-1011. [Abstract] [PDF]  

JK Saha, JN Sengupta, and RK Goyal

Effect of bradykinin on opossum esophageal longitudinal smooth muscle: evidence for novel bradykinin receptors
J Pharmacol Exp Ther 1990 252: 1012-1020. [Abstract] [PDF]  

RA Rabin

Chronic ethanol exposure of PC 12 cells alters adenylate cyclase activity and intracellular cyclic AMP content
J Pharmacol Exp Ther 1990 252: 1021-1027. [Abstract] [PDF]  

RC Baker, M Tucker, and KL Clay

Ethanol inhibits zymosan-stimulated and enhances nonstimulated platelet- activating factor production in a clonal macrophage cell line
J Pharmacol Exp Ther 1990 252: 1028-1033. [Abstract] [PDF]  

DR Blue, RA Bond, N Adham, R Delmendo, AD Michel, RM Eglen, RL Whiting, and DE Clarke

Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol
J Pharmacol Exp Ther 1990 252: 1034-1042. [Abstract] [PDF]  

PL Barrington and RE Ten Eick

Characterization of the electrophysiological effects of metoprolol on isolated feline ventricular myocytes
J Pharmacol Exp Ther 1990 252: 1043-1052. [Abstract] [PDF]  

JH Ngai, PS Roth, and RJ Paul

Effects of endothelium on basal tone and agonist and O2 sensitivity in porcine coronary artery
J Pharmacol Exp Ther 1990 252: 1053-1059. [Abstract] [PDF]  

KO Sedaa, RA Bjur, K Shinozuka, and DP Westfall

Nerve and drug-induced release of adenine nucleosides and nucleotides from rabbit aorta
J Pharmacol Exp Ther 1990 252: 1060-1067. [Abstract] [PDF]  

HA Singer

Phorbol ester-induced stress and myosin light chain phosphorylation in swine carotid medial smooth muscle
J Pharmacol Exp Ther 1990 252: 1068-1074. [Abstract] [PDF]  

CJ Hillard, JJ Pounds, DR Boyer, and AS Bloom

Studies of the role of membrane lipid order in the effects of delta 9- tetrahydrocannabinol on adenylate cyclase activation in heart
J Pharmacol Exp Ther 1990 252: 1075-1082. [Abstract] [PDF]  

AL Killam, SS Nikam, GM Lambert, AR Martin, and DL Nelson

Comparison of two different arterial tissues suggests possible 5- hydroxytryptamine2 receptor heterogeneity
J Pharmacol Exp Ther 1990 252: 1083-1089. [Abstract] [PDF]  

MM Billah, RW Chapman, RW Egan, H Gilchrest, JJ Piwinski, J Sherwood, MI Siegel, RE Jr West, and W Kreutner

Sch 37370: a potent, orally active, dual antagonist of platelet- activating factor and histamine
J Pharmacol Exp Ther 1990 252: 1090-1096. [Abstract] [PDF]  

KA Kirchner, JR Voelker, and DC Brater

Intratubular albumin blunts the response to furosemide-A mechanism for diuretic resistance in the nephrotic syndrome
J Pharmacol Exp Ther 1990 252: 1097-1101. [Abstract] [PDF]  

J Nandi, RL King, DS Kaplan, and RA Levine

Mechanisms of gastric proton pump inhibition by calcium channel antagonists
J Pharmacol Exp Ther 1990 252: 1102-1107. [Abstract] [PDF]  

KA Neve, RA Henningsen, JM Kinzie, T De Paulis, DE Schmidt, RM Kessler, and A Janowsky

Sodium-dependent isomerization of dopamine D-2 receptors characterized using [125I]epidepride, a high-affinity substituted benzamide ligand
J Pharmacol Exp Ther 1990 252: 1108-1116. [Abstract] [PDF]  

TD Lindstrom, WA Althaus, KJ Ruterbories, and D Kau

Pharmacokinetics and disposition of the KS1/4 monoclonal antibody- desacetylvinblastine hydrazide conjugate LY203725 in rats and monkeys
J Pharmacol Exp Ther 1990 252: 1117-1124. [Abstract] [PDF]  

NR Boisse, N Quaglietta, GM Samoriski, and JJ Guarino

Tolerance and physical dependence to a short-acting benzodiazepine, midazolam
J Pharmacol Exp Ther 1990 252: 1125-1133. [Abstract] [PDF]  

CR Lupica, WA Cass, NR Zahniser, and TV Dunwiddie

Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum
J Pharmacol Exp Ther 1990 252: 1134-1141. [Abstract] [PDF]  

N Ogata and T Narahashi

Potent blocking action of chlorpromazine on two types of calcium channels in cultured neuroblastoma cells
J Pharmacol Exp Ther 1990 252: 1142-1149. [Abstract] [PDF]  

MA Moron, CW Stevens, and TL Yaksh

The antiseizure activity of dihydropyridine calcium channel antagonists in the conscious rat
J Pharmacol Exp Ther 1990 252: 1150-1155. [Abstract] [PDF]  

MM Puig, H Turndorf, and W Warner

Effect of pertussis toxin on the interaction of azepexole and halothane
J Pharmacol Exp Ther 1990 252: 1156-1159. [Abstract] [PDF]  

MS Barnette, M Grous, TJ Torphy, and HS 3d Ormsbee

Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation
J Pharmacol Exp Ther 1990 252: 1160-1166. [Abstract] [PDF]  

KD Meisheri, GP 2d Sage, and LA Cipkus-Dubray

Factors affecting rabbit mesenteric artery smooth muscle sensitivity to calcium antagonists
J Pharmacol Exp Ther 1990 252: 1167-1174. [Abstract] [PDF]  

JR Hughes, SW Gust, RM Keenan, and JW Fenwick

Effect of dose on nicotine's reinforcing, withdrawal-suppression and self-reported effects
J Pharmacol Exp Ther 1990 252: 1175-1183. [Abstract] [PDF]  

G Jagadeesh, EJ Jr Cragoe, and RC Deth

Modulation of bovine aortic alpha-2 receptors by Na+, 5'- guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: evidence for receptor G-protein precoupling
J Pharmacol Exp Ther 1990 252: 1184-1196. [Abstract] [PDF]  

K Komori, NA Flavahan, VM Miller, and PM Vanhoutte

Electrophysiological analysis of adrenergic neurotransmission and its modulation by chronic denervation in canine saphenous veins
J Pharmacol Exp Ther 1990 252: 1197-1201. [Abstract] [PDF]  

OH Drummer, J Nicolaci, and D Iakovidis

Biliary excretion and conjugation of diacid angiotensin-converting enzyme inhibitors
J Pharmacol Exp Ther 1990 252: 1202-1206. [Abstract] [PDF]  

M Ichinose and PJ Barnes

A potassium channel activator modulates both excitatory noncholinergic and cholinergic neurotransmission in guinea pig airways
J Pharmacol Exp Ther 1990 252: 1207-1212. [Abstract] [PDF]  

N Perico, J Dadan, M Gabanelli, and G Remuzzi

Cyclooxygenase products and atrial natriuretic peptide modulate renal response to endothelin
J Pharmacol Exp Ther 1990 252: 1213-1220. [Abstract] [PDF]  

L Tahraoui, A Floch, and I Cavero

Functional validation of platelet-activating factor receptor sites characterized biochemically by a specific and reproducible [3H]platelet- activating factor binding in human platelets
J Pharmacol Exp Ther 1990 252: 1221-1227. [Abstract] [PDF]  

K Takeuchi, O Furukawa, M Okada, H Niida, and S Okabe

Influences of stress on gastric alkaline secretion in rats
J Pharmacol Exp Ther 1990 252: 1228-1233. [Abstract] [PDF]  

Y Kawai and T Ohhashi

Age-related changes in relaxant response of vascular smooth muscles to atrial natriuretic peptide
J Pharmacol Exp Ther 1990 252: 1234-1239. [Abstract] [PDF]  

K Hayashi, Y Matsumura, Y Yoshida, T Ohyama, K Hisaki, Y Suzuki, and S Morimoto

Effects of BRL 34915 (cromakalim) on renal hemodynamics and function in anesthetized dogs
J Pharmacol Exp Ther 1990 252: 1240-1246. [Abstract] [PDF]  

T Nakazawa, Y Furuya, T Kaneko, K Yamatsu, H Yoshino, and S Tachibana

Analgesia produced by E-2078, a systemically active dynorphin analog, in mice
J Pharmacol Exp Ther 1990 252: 1247-1254. [Abstract] [PDF]  

JC Drieman, HH Thijssen, and HA Struyker-Boudier

Renal selective N-acetyl-gamma-glutamyl prodrugs. II. Carrier-mediated transport and intracellular conversion as determinants in the renal selectivity of N-acetyl-gamma-glutamyl sulfamethoxazole
J Pharmacol Exp Ther 1990 252: 1255-1260. [Abstract] [PDF]  

T Ohkubo, M Shibata, H Takahashi, and R Inoki

Roles of substance P and somatostatin on transmission of nociceptive information induced by formalin in spinal cord
J Pharmacol Exp Ther 1990 252: 1261-1268. [Abstract] [PDF]  

Y Kanai, O Wada, and S Manabe

Antagonism of gamma-aminobutyric acidA receptor-mediated responses by amino-gamma-carbolines
J Pharmacol Exp Ther 1990 252: 1269-1276. [Abstract] [PDF]  

BS Gan and MD Hollenberg

Distinct coronary artery receptor systems for epidermal growth factor- urogastrone
J Pharmacol Exp Ther 1990 252: 1277-1282. [Abstract] [PDF]  

M Okada, K Mine, and M Fujiwara

The Na(+)-dependent release of endogenous dopamine and noradrenaline from rat brain synaptosomes
J Pharmacol Exp Ther 1990 252: 1283-1288. [Abstract] [PDF]  

H Nagaya, H Satoh, and Y Maki

Possible mechanism for the inhibition of acid formation by the proton pump inhibitor AG-1749 in isolated canine parietal cells
J Pharmacol Exp Ther 1990 252: 1289-1295. [Abstract] [PDF]  

R Plevin, PJ Owen, DB Marriott, JA Jones, and MR Boarder

Role of phosphoinositide turnover and cyclic AMP accumulation in prostaglandin-stimulated noradrenaline release from cultured adrenal chromaffin cells
J Pharmacol Exp Ther 1990 252: 1296-1303. [Abstract] [PDF]  

S Fujimoto and T Matsuda

Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats
J Pharmacol Exp Ther 1990 252: 1304-1311. [Abstract] [PDF]  

S Giuliani, IT Lippe, CA Maggi, and A Meli

Dual effects of cholecystokinin-octapeptide on duodenal motility of urethane-anesthetized rats
J Pharmacol Exp Ther 1990 252: 1312-1317. [Abstract] [PDF]  

SR O'Donnell, JC Wanstall, and XP Zeng

Pinacidil antagonism of endothelin-induced contractions of smooth muscle in the lungs: differences between tracheal and pulmonary artery preparations
J Pharmacol Exp Ther 1990 252: 1318-1323. [Abstract] [PDF]  

U Scheurer, F Wenger, A Caliezi, E Drack, L Varga, and F Halter

Different motor actions of dynorphins and nonpeptide kappa opioid receptor agonists in the isolated rat colon
J Pharmacol Exp Ther 1990 252: 1324-1330. [Abstract] [PDF]  

DP Bloxham, D Bradshaw, CH Cashin, BB Dodge, EJ Lewis, D Westmacott, and CR Self

Biologic properties of romazarit (Ro 31-3948), a potential disease- modifying antirheumatic drug
J Pharmacol Exp Ther 1990 252: 1331-1340. [Abstract] [PDF]  

V Nerme, T Abrahamsson, and G Vauquelin

Chronic isoproterenol administration causes altered beta adrenoceptor- Gs-coupling in guinea pig lung
J Pharmacol Exp Ther 1990 252: 1341-1346. [Abstract] [PDF]  

RD Ciaranello, GL Tan, and R Dean

G-protein-linked serotonin receptors in mouse kidney exhibit identical properties to 5-HT1b receptors in brain
J Pharmacol Exp Ther 1990 252: 1347-1354. [Abstract] [PDF]  

BJ Keller, H Yamanaka, DC Liang, FC Kauffman, and RG Thurman

O2-dependent hepatotoxicity due to ethylhexanol in the perfused rat liver: mitochondria as a site of action
J Pharmacol Exp Ther 1990 252: 1355-1360. [Abstract] [PDF]  

RM Caudle and C Chavkin

Mu opioid receptor activation reduces inhibitory postsynaptic potentials in hippocampal CA3 pyramidal cells of rat and guinea pig
J Pharmacol Exp Ther 1990 252: 1361-1369. [Abstract] [PDF]  

MC Austin and PW Kalivas

Enkephalinergic and GABAergic modulation of motor activity in the ventral pallidum
J Pharmacol Exp Ther 1990 252: 1370-1377. [Abstract] [PDF]  

DA Craig and DE Clarke

Pharmacological characterization of a neuronal receptor for 5- hydroxytryptamine in guinea pig ileum with properties similar to the 5- hydroxytryptamine receptor [published erratum appears in J Pharmacol Exp Ther 1990 May;253(2):i]
J Pharmacol Exp Ther 1990 252: 1378-1386. [Abstract] [PDF]  

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