ARTICLES:

CW Stevens and TL Yaksh

Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion
J Pharmacol Exp Ther 1989 250: 1-8. [Abstract] [PDF]  

EK Jackson

Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats
J Pharmacol Exp Ther 1989 250: 9-21. [Abstract] [PDF]  

SJ Haleen, RP Steffen, I Sircar, TC Major, MD Taylor, TA Pugsley, and RE Weishaar

PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties
J Pharmacol Exp Ther 1989 250: 22-30. [Abstract] [PDF]  

RG Pendleton, G Gessner, and E Horner

Studies defining minimal receptor domains for angiotensin II
J Pharmacol Exp Ther 1989 250: 31-36. [Abstract] [PDF]  

DH Bobker and JT Williams

Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors
J Pharmacol Exp Ther 1989 250: 37-43. [Abstract] [PDF]  

RJ Heaslip and BD Sickels

Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism
J Pharmacol Exp Ther 1989 250: 44-51. [Abstract] [PDF]  

GJ Marek, AA Li, and LS Seiden

Selective 5-hydroxytryptamine2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule
J Pharmacol Exp Ther 1989 250: 52-59. [Abstract] [PDF]  

GJ Marek, AA Li, and LS Seiden

Evidence for involvement of 5-hydroxytryptamine1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low- rate 72-second behavior
J Pharmacol Exp Ther 1989 250: 60-71. [Abstract] [PDF]  

G Bagdy, K Szemeredi, B Kanyicska, and DL Murphy

Different serotonin receptors mediate blood pressure, heart rate, plasma catecholamine and prolactin responses to m- chlorophenylpiperazine in conscious rats
J Pharmacol Exp Ther 1989 250: 72-78. [Abstract] [PDF]  

S Barone, PC Churchill, and KA Jacobson

Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines
J Pharmacol Exp Ther 1989 250: 79-85. [Abstract] [PDF]  

J Zawilska and PM Iuvone

Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2- dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland
J Pharmacol Exp Ther 1989 250: 86-92. [Abstract] [PDF]  

RE Howell, PN Lanken, JH Hansen-Flaschen, FR Haselton, SM Albelda, and AP Fishman

Pulmonary extraction of propranolol in normal and oxygen-toxic sheep
J Pharmacol Exp Ther 1989 250: 93-99. [Abstract] [PDF]  

JW Ferkany, DJ Kyle, J Willets, WJ Rzeszotarski, ME Guzewska, SR Ellenberger, SM Jones, AI Sacaan, LD Snell, and S Borosky

Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D- aspartate receptor antagonist
J Pharmacol Exp Ther 1989 250: 100-109. [Abstract] [PDF]  

BS Schonwetter, RR Luedtke, MP Kung, J Billings, HF Kung, and PB Molinoff

Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM
J Pharmacol Exp Ther 1989 250: 110-116. [Abstract] [PDF]  

DM Niedzwiecki, LX Cubeddu, and RB Mailman

Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum
J Pharmacol Exp Ther 1989 250: 117-125. [Abstract] [PDF]  

DM Niedzwiecki, LX Cubeddu, and RB Mailman

Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine
J Pharmacol Exp Ther 1989 250: 126-133. [Abstract] [PDF]  

DJ Greenblatt, BL Ehrenberg, J Gunderman, JM Scavone, NT Tai, JS Harmatz, and RI Shader

Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam
J Pharmacol Exp Ther 1989 250: 134-140. [Abstract] [PDF]  

JC Chen, PB Crino, PW Schnepper, AC To, and L Volicer

Increased serotonin efflux by a partially oxidized serotonin: tryptamine-4,5-dione
J Pharmacol Exp Ther 1989 250: 141-148. [Abstract] [PDF]  

LS Ramsammy, C Josepovitz, BP Lane, and GJ Kaloyanides

Polyaspartic acid protects against gentamicin nephrotoxicity in the rat
J Pharmacol Exp Ther 1989 250: 149-153. [Abstract] [PDF]  

TD Bjornsson, DE Schneider, and H Jr Berger

Aspirin acetylates fibrinogen and enhances fibrinolysis. Fibrinolytic effect is independent of changes in plasminogen activator levels
J Pharmacol Exp Ther 1989 250: 154-161. [Abstract] [PDF]  

BM Baron, MW Dudley, DR McCarty, FP Miller, IJ Reynolds, and CJ Schmidt

Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo
J Pharmacol Exp Ther 1989 250: 162-169. [Abstract] [PDF]  

CF Neely, PJ Kadowitz, H Lippton, M Neiman, and AL Hyman

Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed
J Pharmacol Exp Ther 1989 250: 170-176. [Abstract] [PDF]  

Y Ohno and JE Warnick

Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro
J Pharmacol Exp Ther 1989 250: 177-183. [Abstract] [PDF]  

KL Preston, GE Bigelow, WK Bickel, and IA Liebson

Drug discrimination in human postaddicts: agonist-antagonist opioids
J Pharmacol Exp Ther 1989 250: 184-196. [Abstract] [PDF]  

CP France, AM Snyder, and JH Woods

Analgesic effects of phencyclidine-like drugs in rhesus monkeys
J Pharmacol Exp Ther 1989 250: 197-201. [Abstract] [PDF]  

MD Jr Dulaney, RW Rockhold, AC Porter, B Hoskins, and IK Ho

Changes in drinking activity, urine volume and urinary electrolyte excretion after intracerebroventricular administration of diisopropylfluorophosphate
J Pharmacol Exp Ther 1989 250: 202-209. [Abstract] [PDF]  

AK Cho, M Hiramatsu, RN Pechnick, and E Di Stefano

Pharmacokinetic and pharmacodynamic evaluation of phencyclidine and its decadeutero variant
J Pharmacol Exp Ther 1989 250: 210-215. [Abstract] [PDF]  

JF Tomera and J Martyn

Intraperitoneal endotoxin but not protein malnutrition shifts d- tubocurarine dose-response curves in mouse gastrocnemius muscle
J Pharmacol Exp Ther 1989 250: 216-220. [Abstract] [PDF]  

JC Deutsch and JF Kolhouse

Structural specificity of mechanisms controlling the hepatic uptake and biliary output of methotrexate in the rat
J Pharmacol Exp Ther 1989 250: 221-226. [Abstract] [PDF]  

MM Foreman, RW Fuller, MD Hynes, JS Gidda, CL Nichols, JM Schaus, EC Kornfeld, and JA Clemens

Preclinical studies on quinelorane, a potent and highly selective D2- dopaminergic agonist
J Pharmacol Exp Ther 1989 250: 227-235. [Abstract] [PDF]  

EM Kudlacz, HA Navarro, and TA Slotkin

Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation
J Pharmacol Exp Ther 1989 250: 236-240. [Abstract] [PDF]  

KW Locke, B Gorney, M Cornfeldt, and S Fielding

Characterization of the discriminative stimulus effects of physostigmine in the rat
J Pharmacol Exp Ther 1989 250: 241-246. [Abstract] [PDF]  

AM Torres, JV Rodriguez, and MM Elias

Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin
J Pharmacol Exp Ther 1989 250: 247-253. [Abstract] [PDF]  

T Tadano, S Satoh, N Satoh, K Kisara, Y Arai, SK Kim, and H Kinemuchi

Potentiation of para-hydroxyamphetamine-induced head-twitch response by inhibition of monoamine oxidase type A in the brain
J Pharmacol Exp Ther 1989 250: 254-260. [Abstract] [PDF]  

U Quast and NS Cook

In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide
J Pharmacol Exp Ther 1989 250: 261-271. [Abstract] [PDF]  

Y Kitada, M Kobayashi, A Narimatsu, and Y Ohizumi

Potent stimulation of myofilament force and adenosine triphosphatase activity of canine cardiac muscle through a direct enhancement of troponin C Ca++ binding by MCI-154, a novel cardiotonic agent
J Pharmacol Exp Ther 1989 250: 272-277. [Abstract] [PDF]  

M Hiraoka and Z Fan

Activation of ATP-sensitive outward K+ current by nicorandil (2- nicotinamidoethyl nitrate) in isolated ventricular myocytes
J Pharmacol Exp Ther 1989 250: 278-285. [Abstract] [PDF]  

E Okabe, M Sugihara, K Tanaka, H Sasaki, and H Ito

Calmodulin and free oxygen radicals interaction with steady-state calcium accumulation and passive calcium permeability of cardiac sarcoplasmic reticulum
J Pharmacol Exp Ther 1989 250: 286-292. [Abstract] [PDF]  

O Marquis, C Robaut, and I Cavero

Evidence for the existence and ionic modulation of platelet-activating factor receptors mediating degranulatory responses in human polymorphonuclear leukocytes
J Pharmacol Exp Ther 1989 250: 293-300. [Abstract] [PDF]  

B Zimmerli, J Valantinas, and PJ Meier

Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles
J Pharmacol Exp Ther 1989 250: 301-308. [Abstract] [PDF]  

JP Gies, C Bertrand, P Vanderheyden, F Waeldele, P Dumont, G Pauli, and Y Landry

Characterization of muscarinic receptors in human, guinea pig and rat lung
J Pharmacol Exp Ther 1989 250: 309-315. [Abstract] [PDF]  

BM Bennett, DC Leitman, H Schroder, JH Kawamoto, K Nakatsu, and F Murad

Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines
J Pharmacol Exp Ther 1989 250: 316-323. [Abstract] [PDF]  

T Nohjoh, H Suzuki, Y Sawada, Y Sugiyama, T Iga, and M Hanano

Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus
J Pharmacol Exp Ther 1989 250: 324-328. [Abstract] [PDF]  

M Mousli, C Bronner, JL Bueb, E Tschirhart, JP Gies, and Y Landry

Activation of rat peritoneal mast cells by substance P and mastoparan
J Pharmacol Exp Ther 1989 250: 329-335. [Abstract] [PDF]  

M Wong and PG Wells

Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)
J Pharmacol Exp Ther 1989 250: 336-342. [Abstract] [PDF]  

YY Zeng, CG Benishin, and PK Pang

Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride
J Pharmacol Exp Ther 1989 250: 343-351. [Abstract] [PDF]  

YY Zeng, CG Benishin, and PK Pang

Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'- (gamma)triphosphate
J Pharmacol Exp Ther 1989 250: 352-357. [Abstract] [PDF]  

XM Yang, ZP Luo, and JH Zhou

Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate
J Pharmacol Exp Ther 1989 250: 358-363. [Abstract] [PDF]  

U Ravens, XL Wang, and E Wettwer

Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes
J Pharmacol Exp Ther 1989 250: 364-370. [Abstract] [PDF]  

FJ Ayesta and J Florez

Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance
J Pharmacol Exp Ther 1989 250: 371-378. [Abstract] [PDF]  

M Frenken

Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery
J Pharmacol Exp Ther 1989 250: 379-387. [Abstract] [PDF]  

H Ishihara, H Ozaki, K Sato, M Hori, H Karaki, S Watabe, Y Kato, N Fusetani, K Hashimoto, and D Uemura

Calcium-independent activation of contractile apparatus in smooth muscle by calyculin-A
J Pharmacol Exp Ther 1989 250: 388-396. [Abstract] [PDF]  

A Zaza, G Malfatto, and MR Rosen

Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart
J Pharmacol Exp Ther 1989 250: 397-405. [Abstract] [PDF]  

MW Kalichman, HC Powell, and RR Myers

Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve
J Pharmacol Exp Ther 1989 250: 406-413. [Abstract] [PDF]  

K Beaumont, DA Vaughn, and DP Healy

Thiazide diuretic receptors: autoradiographic localization in rat kidney with [3H]metolazone
J Pharmacol Exp Ther 1989 250: 414-419. [Abstract] [PDF]  

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