ARTICLES:

LG Miller, DJ Greenblatt, RB Roy, F Lopez, and L Wecker

Dietary choline intake modulates benzodiazepine receptor binding and gamma-aminobutyric acidA receptor function in mouse brain
J Pharmacol Exp Ther 1989 248: 1-6. [Abstract] [PDF]  

TD Djokic, JA Nadel, DJ Dusser, K Sekizawa, PD Graf, and DB Borson

Inhibitors of neutral endopeptidase potentiate electrically and capsaicin-induced noncholinergic contraction in guinea pig bronchi
J Pharmacol Exp Ther 1989 248: 7-11. [Abstract] [PDF]  

S McArdle, LC Garg, and FT Crews

Cholinergic receptors in renal medullary collecting duct cells
J Pharmacol Exp Ther 1989 248: 12-16. [Abstract] [PDF]  

GB Corcoran and DE Salazar

Obesity as a risk factor in drug-induced organ injury. IV. Increased gentamicin nephrotoxicity in the obese overfed rat
J Pharmacol Exp Ther 1989 248: 17-22. [Abstract] [PDF]  

MJ Mangino, EM Brunt, P Von Doersten, and CB Anderson

Effects of the thromboxane synthesis inhibitor CGS-12970 on experimental acute renal allograft rejection
J Pharmacol Exp Ther 1989 248: 23-28. [Abstract] [PDF]  

SM Evans and CE Johanson

Discriminative stimulus properties of midazolam in the pigeon
J Pharmacol Exp Ther 1989 248: 29-38. [Abstract] [PDF]  

NE Farber and GJ Gross

Cardioprotective effects of a new vascular intracellular calcium antagonist, KT-362, in the stunned myocardium
J Pharmacol Exp Ther 1989 248: 39-43. [Abstract] [PDF]  

SL Lee, S Levitsky, and H Feinberg

Effects of exogenous vasoconstrictors on coronary vascular resistance and prostacyclin production of the quiescent heart: the inhibitory effect of aspirin
J Pharmacol Exp Ther 1989 248: 44-49. [Abstract] [PDF]  

RW Fuller and KW Perry

Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats
J Pharmacol Exp Ther 1989 248: 50-56. [Abstract] [PDF]  

RD Wilkerson

Cardiovascular effects of cocaine: enhancement by yohimbine and atropine
J Pharmacol Exp Ther 1989 248: 57-61. [Abstract] [PDF]  

MR Lakshman, SJ Chirtel, LL Chambers, and PJ Coutlakis

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on lipid synthesis and lipogenic enzymes in the rat
J Pharmacol Exp Ther 1989 248: 62-66. [Abstract] [PDF]  

TR Bosin

Oxidant stress stimulates active transport of serotonin by platelets
J Pharmacol Exp Ther 1989 248: 67-72. [Abstract] [PDF]  

KN Hawkins, RJ Knapp, GK Lui, K Gulya, W Kazmierski, YP Wan, JT Pelton, VJ Hruby, and HI Yamamura

[3H]-[H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2] ([3H]CTOP), a potent and highly selective peptide for mu opioid receptors in rat brain
J Pharmacol Exp Ther 1989 248: 73-80. [Abstract] [PDF]  

J Latifpour, A Gousse, S Kondo, T Morita, and RM Weiss

Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors
J Pharmacol Exp Ther 1989 248: 81-88. [Abstract] [PDF]  

M Williams, DA Bennett, PS Loo, AF Braunwalder, CL Amrick, DE Wilson, TN Thompson, M Schmutz, N Yokoyoma, and JW Wasley

CGS 20625, a novel pyrazolopyridine anxiolytic
J Pharmacol Exp Ther 1989 248: 89-96. [Abstract] [PDF]  

K Bohmaker, T Puza, M Goldstein, and E Meller

Absence of spare autoreceptors regulating dopamine agonist inhibition of tyrosine hydroxylation in slices of rat striatum
J Pharmacol Exp Ther 1989 248: 97-103. [Abstract] [PDF]  

RH Kennedy and E Seifen

Aging: ouabain-sensitive 86Rb+ uptake rate and responsiveness to digoxin in rat left atrial muscle
J Pharmacol Exp Ther 1989 248: 104-110. [Abstract] [PDF]  

JJ Waite and DJ Jenden

Spontaneous regeneration of free muscarinic receptor after alkylation by BM 123. I. Recovery in vivo and in cell culture
J Pharmacol Exp Ther 1989 248: 111-118. [Abstract] [PDF]  

JJ Waite and DJ Jenden

Spontaneous regeneration of free muscarinic receptor after alkylation by BM 123. II. Recovery in broken cell preparations
J Pharmacol Exp Ther 1989 248: 119-126. [Abstract] [PDF]  

SJ Heishman, ML Stitzer, GE Bigelow, and IA Liebson

Acute opioid physical dependence in postaddict humans: naloxone dose effects after brief morphine exposure
J Pharmacol Exp Ther 1989 248: 127-134. [Abstract] [PDF]  

JG Drewett, GJ Trachte, and GR Marchand

Atrial natriuretic factor inhibits adrenergic and purinergic neurotransmission in the rabbit isolated vas deferens
J Pharmacol Exp Ther 1989 248: 135-142. [Abstract] [PDF]  

CW Bazil and KP Minneman

Effects of clinically effective concentrations of halothane on adrenergic and cholinergic synapses in rat brain in vitro
J Pharmacol Exp Ther 1989 248: 143-148. [Abstract] [PDF]  

RJ Winquist, LA Heaney, AA Wallace, EP Baskin, RB Stein, ML Garcia, and GJ Kaczorowski

Glyburide blocks the relaxation response to BRL 34915 (cromakalim), minoxidil sulfate and diazoxide in vascular smooth muscle
J Pharmacol Exp Ther 1989 248: 149-156. [Abstract] [PDF]  

MT Moslen, RF Whitehead, AE Ferguson, and MF Kanz

Protection by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug, against 1,1-dichloroethylene hepatotoxicity in rats is associated with decreases in toxin metabolism and cytochrome P-450
J Pharmacol Exp Ther 1989 248: 157-163. [Abstract] [PDF]  

D Rampe, A Skattebol, DJ Triggle, and AM Brown

Effects of McN-6186 on voltage-dependent Ca++ channels in heart and pituitary cells
J Pharmacol Exp Ther 1989 248: 164-170. [Abstract] [PDF]  

CC Felder, PA Jose, and J Axelrod

The dopamine-1 agonist, SKF 82526, stimulates phospholipase-C activity independent of adenylate cyclase
J Pharmacol Exp Ther 1989 248: 171-175. [Abstract] [PDF]  

GM Pollack, DD Shen, and MB Dorr

Contribution of metabolites to the route- and time-dependent hepatic effects of di-(2-ethylhexyl)phthalate in the rat
J Pharmacol Exp Ther 1989 248: 176-181. [Abstract] [PDF]  

DW Potter, NR Pumford, JA Hinson, RW Benson, and DW Roberts

Epitope characterization of acetaminophen bound to protein and nonprotein sulfhydryl groups by an enzyme-linked immunosorbent assay
J Pharmacol Exp Ther 1989 248: 182-189. [Abstract] [PDF]  

NR Pumford, JA Hinson, DW Potter, KL Rowland, RW Benson, and DW Roberts

Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen adducts in serum and liver proteins of acetaminophen-treated mice
J Pharmacol Exp Ther 1989 248: 190-196. [Abstract] [PDF]  

ML Cohen, W Bloomquist, JS Gidda, and W Lacefield

Comparison of the 5-HT3 receptor antagonist properties of ICS 205-930, GR38032F and zacopride
J Pharmacol Exp Ther 1989 248: 197-201. [Abstract] [PDF]  

KM Sanders, JB Reed, and RG Berry

Gradient in the effects of ethyl alcohol on canine gastric antral circular muscles
J Pharmacol Exp Ther 1989 248: 202-207. [Abstract] [PDF]  

EW Black, SJ Strada, RL Jr Garrett, PR Kvietys, WJ Thompson, and JA Norman

Inhibition of gastric acid secretion in vivo and in vitro by a new calmodulin antagonist, CGS 9343B
J Pharmacol Exp Ther 1989 248: 208-214. [Abstract] [PDF]  

GA Kopia and RE Valocik

Demonstration of specific dopamine-1 receptor-mediated coronary vasodilation in the anesthetized dog
J Pharmacol Exp Ther 1989 248: 215-221. [Abstract] [PDF]  

JJ Liccione and MD Maines

Manganese-mediated increase in the rat brain mitochondrial cytochrome P- 450 and drug metabolism activity: susceptibility of the striatum
J Pharmacol Exp Ther 1989 248: 222-228. [Abstract] [PDF]  

B Escalante, WC Sessa, JR Falck, P Yadagiri, and ML Schwartzman

Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase
J Pharmacol Exp Ther 1989 248: 229-232. [Abstract] [PDF]  

EH Ohlstein, S Horohonich, RJ Shebuski, and RR Jr Ruffolo

Localization and characterization of alpha-2 adrenoceptors in the isolated canine pulmonary vein
J Pharmacol Exp Ther 1989 248: 233-239. [Abstract] [PDF]  

RA Keith, TF Hwang, VS Murthy, ST Kau, AI Salama, and RE Giles

ICI 147,798: a slowly dissociable beta adrenoceptor antagonist that causes insurmountable beta-1 and surmountable beta-2 adrenoceptor antagonism in isolated tissues
J Pharmacol Exp Ther 1989 248: 240-248. [Abstract] [PDF]  

VS Murthy, TF Hwang, R Wurm, ME Zagar, RA Keith, ST Kau, AI Salama, and RE Giles

Insurmountable beta receptor blockade by ICI 147,798 in rabbits
J Pharmacol Exp Ther 1989 248: 249-255. [Abstract] [PDF]  

TJ Cicero, L O'Connor, B Nock, ML Adams, BT Miller, RD Bell, and ER Meyer

Age-related differences in the sensitivity to opiate-induced perturbations in reproductive endocrinology in the developing and adult male rat
J Pharmacol Exp Ther 1989 248: 256-261. [Abstract] [PDF]  

KR Gogas and LB Hough

Inhibition of naloxone-resistant antinociception by centrally administered H2-antagonists
J Pharmacol Exp Ther 1989 248: 262-267. [Abstract] [PDF]  

AW Baird and HS Margolius

Bradykinin stimulates electrogenic bicarbonate secretion by the guinea pig gallbladder
J Pharmacol Exp Ther 1989 248: 268-272. [Abstract] [PDF]  

MS Kleven and SB Sparber

Morphine blocks and naloxone enhances suppression of operant behavior by low doses of 3-isobutyl-1-methylxanthine
J Pharmacol Exp Ther 1989 248: 273-277. [Abstract] [PDF]  

CA Maggi, F Borsini, A Lecci, S Giuliani, P Meli, L Gragnani, and A Meli

Effect of acute or chronic administration of imipramine on spinal and supraspinal micturition reflexes in rats
J Pharmacol Exp Ther 1989 248: 278-285. [Abstract] [PDF]  

E Vannier, M Roch-Arveiller, B Molinie, B Terlain, and JP Giroud

Effects of ketoprofen and indomethacin on leukocyte migration in two models of pleurisy induced by carrageenan or zymosan-activated serum in rats
J Pharmacol Exp Ther 1989 248: 286-291. [Abstract] [PDF]  

N Frossard, KJ Rhoden, and PJ Barnes

Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase
J Pharmacol Exp Ther 1989 248: 292-298. [Abstract] [PDF]  

F Passarelli and T Costa

Mu and delta opioid receptors inhibit serotonin release in rat hippocampus
J Pharmacol Exp Ther 1989 248: 299-305. [Abstract] [PDF]  

S Takeo, K Tanonaka, K Shimizu, K Hirai, K Miyake, and R Minematsu

Beneficial effects of lidocaine and disopyramide on oxygen-deficiency- induced contractile failure and metabolic disturbance in isolated rabbit hearts
J Pharmacol Exp Ther 1989 248: 306-314. [Abstract] [PDF]  

A Lelo, G Kjellen, DJ Birkett, and JO Miners

Paraxanthine metabolism in humans: determination of metabolic partial clearances and effects of allopurinol and cimetidine
J Pharmacol Exp Ther 1989 248: 315-319. [Abstract] [PDF]  

JA Aram, D Martin, M Tomczyk, S Zeman, J Millar, G Pohler, and D Lodge

Neocortical epileptogenesis in vitro: studies with N-methyl-D- aspartate, phencyclidine, sigma and dextromethorphan receptor ligands
J Pharmacol Exp Ther 1989 248: 320-328. [Abstract] [PDF]  

LJ Hellebrekers, WE van den Brom, and JA Mol

Plasma arginine vasopressin response to intravenous methadone and naloxone in conscious dogs
J Pharmacol Exp Ther 1989 248: 329-333. [Abstract] [PDF]  

M Livio, A Benigni, C Zoja, R Begnis, C Morelli, M Rossini, S Garattini, and G Remuzzi

Differential inhibition by aspirin of platelet thromboxane and renal prostaglandins in the rat
J Pharmacol Exp Ther 1989 248: 334-341. [Abstract] [PDF]  

AG Meehan and DF Story

Interaction of the prejunctional inhibitory action of 5- hydroxytryptamine on noradrenergic transmission with neuronal amine uptake in rabbit isolated ear artery
J Pharmacol Exp Ther 1989 248: 342-347. [Abstract] [PDF]  

PT Reeves, RF Minchin, and KF Ilett

In vivo mechanisms for the enhanced acetylation of sulfamethazine in the rabbit after hydrocortisone treatment
J Pharmacol Exp Ther 1989 248: 348-352. [Abstract] [PDF]  

M Pretolani, J Lefort, C Dumarey, and BB Vargaftig

Role of lipoxygenase metabolites for the hyper-responsiveness to platelet-activating factor of lungs from actively sensitized guinea pigs
J Pharmacol Exp Ther 1989 248: 353-359. [Abstract] [PDF]  

S Kacew

Inhibition of gentamicin-induced nephrotoxicity by pyridoxal-5'- phosphate in the rat
J Pharmacol Exp Ther 1989 248: 360-366. [Abstract] [PDF]  

N Sato, H Hashimoto, Y Takiguchi, and M Nakashima

Altered responsiveness to sympathetic nerve stimulation and agonists of isolated left atria of diabetic rats: no evidence for involvement of hypothyroidism
J Pharmacol Exp Ther 1989 248: 367-371. [Abstract] [PDF]  

SC Dennis, WA Coetzee, JW de Jong, W Clusin, and LH Opie

Effects of coronary flow, pacing rate, isoprenaline and diltiazem on ischemic ventricular arrhythmias in guinea pig hearts
J Pharmacol Exp Ther 1989 248: 372-377. [Abstract] [PDF]  

I Sano, K Taniyama, and C Tanaka

Cholecystokinin, but not gastrin, induces gamma-aminobutyric acid release from myenteric neurons of the guinea pig ileum
J Pharmacol Exp Ther 1989 248: 378-383. [Abstract] [PDF]  

MD Hollenberg, I Muramatsu, H Itoh, P Patel, SG Yang, and K Lederis

Contractile actions of epidermal growth factor-urogastrone in isolated smooth muscle preparations from guinea pig stomach: structure-activity relationships and comparison with the effects of human transforming growth factor-alpha
J Pharmacol Exp Ther 1989 248: 384-390. [Abstract] [PDF]  

WP Burkard, EP Bonetti, M Da Prada, JR Martin, P Polc, R Schaffner, R Scherschlicht, F Hefti, RK Muller, and PC Wyss

Pharmacological profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A
J Pharmacol Exp Ther 1989 248: 391-399. [Abstract] [PDF]  

M Da Prada, R Kettler, HH Keller, WP Burkard, D Muggli-Maniglio, and WE Haefely

Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A
J Pharmacol Exp Ther 1989 248: 400-414. [Abstract] [PDF]  

E Somekh, D Douer, N Shaked, and E Rubinstein

In vitro effects of ciprofloxacin and pefloxacin on growth of normal human hematopoietic progenitor cells and on leukemic cell lines
J Pharmacol Exp Ther 1989 248: 415-418. [Abstract] [PDF]  

G Eisenhofer, D Hovevey-Sion, IJ Kopin, R Miletich, KL Kirk, R Finn, and DS Goldstein

Neuronal uptake and metabolism of 2- and 6-fluorodopamine: false neurotransmitters for positron emission tomographic imaging of sympathetically innervated tissues
J Pharmacol Exp Ther 1989 248: 419-427. [Abstract] [PDF]  

FG Russell, AC Wouterse, and CA van Ginneken

Renal clearance of substituted hippurates in the dog. I. Benzoylglycine (hippurate) and methyl-substituted benzoylglycines
J Pharmacol Exp Ther 1989 248: 428-435. [Abstract] [PDF]  

FG Russel, AC Wouterse, and CA van Ginneken

Renal clearance of substituted hippurates in the dog. II. 4-Amino-, hydroxy- and methoxy-substituted benzoylglycines
J Pharmacol Exp Ther 1989 248: 436-446. [Abstract] [PDF]  

MI Sweeney, TD White, and J Sawynok

Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord
J Pharmacol Exp Ther 1989 248: 447-454. [Abstract] [PDF]  

A Saito, T Masaki, Y Uchiyama, TJ Lee, and K Goto

Calcitonin gene-related peptide and vasodilator nerves in large cerebral arteries of cats
J Pharmacol Exp Ther 1989 248: 455-462. [Abstract] [PDF]  

AS Basile, GT Bolger, HW Lueddens, and P Skolnick

Electrophysiological actions of Ro5-4864 on cerebellar Purkinje neurons: evidence for "peripheral" benzodiazepine receptor-mediated depression
J Pharmacol Exp Ther 1989 248: 463-469. [Abstract] [PDF]  

GE Duncan, IA Paul, KR Powell, JB Fassberg, WE Stumpf, and GR Breese

Neuroanatomically selective down-regulation of beta adrenergic receptors by chronic imipramine treatment: relationships to the topography of [3H]imipramine and [3H] desipramine binding sites
J Pharmacol Exp Ther 1989 248: 470-477. [Abstract] [PDF]  

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