ARTICLES:

PC Wong, AT Chiu, WA Price, MJ Thoolen, DJ Carini, AL Johnson, RI Taber, and PB Timmermans

Nonpeptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-(2-chlorobenzyl)imidazole-5- acetic acid, sodium salt (S-8307)
J Pharmacol Exp Ther 1988 247: 1-7. [Abstract] [PDF]  

CP Sung, AJ Arleth, K Shikano, and BA Berkowitz

Characterization and function of bradykinin receptors in vascular endothelial cells
J Pharmacol Exp Ther 1988 247: 8-13. [Abstract] [PDF]  

LL Devaud and TF Murray

Involvement of peripheral-type benzodiazepine receptors in the proconvulsant actions of pyrethroid insecticides
J Pharmacol Exp Ther 1988 247: 14-22. [Abstract] [PDF]  

JF French and MA Matlib

Identification of a high-affinity peripheral-type benzodiazepine binding site in rat aortic smooth muscle membranes
J Pharmacol Exp Ther 1988 247: 23-28. [Abstract] [PDF]  

AD Weissman, TP Su, JC Hedreen, and ED London

Sigma receptors in post-mortem human brains
J Pharmacol Exp Ther 1988 247: 29-33. [Abstract] [PDF]  

PJ Silver, RE Lepore, B O'Connor, BM Lemp, LT Hamel, RG Bentley, and AL Harris

Inhibition of the low Km cyclic AMP phosphodiesterase and activation of the cyclic AMP system in vascular smooth muscle by milrinone
J Pharmacol Exp Ther 1988 247: 34-42. [Abstract] [PDF]  

GJ Trachte, PJ Hook, JR Kemp, EP Acosta, and RJ Ziegler

Thromboxane synthesis and actions in isolated adrenergic nerve (pheochromocytoma-12) cells
J Pharmacol Exp Ther 1988 247: 43-46. [Abstract] [PDF]  

WK Bickel, ML Stitzer, GE Bigelow, IA Liebson, DR Jasinski, and RE Johnson

Buprenorphine: dose-related blockade of opioid challenge effects in opioid dependent humans
J Pharmacol Exp Ther 1988 247: 47-53. [Abstract] [PDF]  

JD Winkler, HM Sarau, JJ Foley, and ST Crooke

Leukotriene D4-induced homologous desensitization in basal and differentiated U-937 cells: characterization with the partial agonist leukotriene E4 and assessment of receptor reserve
J Pharmacol Exp Ther 1988 247: 54-62. [Abstract] [PDF]  

JP Pieroni, F Dray, CR Pace-Asciak, and JC McGiff

Identification of 6-keto-prostaglandin E1 obtained from isolated perfused kidney of the rabbit
J Pharmacol Exp Ther 1988 247: 63-68. [Abstract] [PDF]  

AL Siren and G Feuerstein

Cardiovascular effects of rat calcitonin gene-related peptide in the conscious rat
J Pharmacol Exp Ther 1988 247: 69-78. [Abstract] [PDF]  

DM Stone, M Johnson, GR Hanson, and JW Gibb

Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine
J Pharmacol Exp Ther 1988 247: 79-87. [Abstract] [PDF]  

JK Zubieta, EJ Jr Cragoe, and LX Cubeddu

Effects of amiloride and 5-(N,N-hexamethylene)amiloride on dopaminergic and cholinergic neurotransmission
J Pharmacol Exp Ther 1988 247: 88-95. [Abstract] [PDF]  

EJ Zambraski, DC Atkinson, and J Diamond

Effects of salicylate vs. aspirin on renal prostaglandins and function in normal and sodium-depleted dogs
J Pharmacol Exp Ther 1988 247: 96-103. [Abstract] [PDF]  

N Jaiswal, G Lambrecht, E Mutschler, and KU Malik

Contribution of M2 alpha and M2 beta muscarinic receptors to the action of cholinergic stimuli on prostaglandin synthesis and mechanical function in the isolated rabbit heart
J Pharmacol Exp Ther 1988 247: 104-113. [Abstract] [PDF]  

SG Oakes, PA Iaizzo, E Richelson, and G Powis

Histamine-induced intracellular free Ca++, inositol phosphates and electrical changes in murine N1E-115 neuroblastoma cells
J Pharmacol Exp Ther 1988 247: 114-121. [Abstract] [PDF]  

RN Daly, AC Sulpizio, B Levitt, RM DeMarinis, JW Regan, RR Jr Ruffolo, and JP Hieble

Evidence for heterogeneity between pre- and postjunctional alpha-2 adrenoceptors using 9-substituted 3-benzazepines
J Pharmacol Exp Ther 1988 247: 122-128. [Abstract] [PDF]  

SB Weinberger and JL Jr Martinez

Characterization of hydrolysis of [leu]enkephalin and D-ala2-[L- leu]enkephalin in rat plasma
J Pharmacol Exp Ther 1988 247: 129-135. [Abstract] [PDF]  

T Scott and KK McMahon

Antagonists and agonists interactions with the muscarinic receptor of the rat large airways
J Pharmacol Exp Ther 1988 247: 136-142. [Abstract] [PDF]  

PL Smith, GP McCafferty, JD Fondacaro, MA Wasserman, E Elton, and FM Ryan

Effects of putative thromboxane receptor agonists and antagonists on rat small intestinal ion transport
J Pharmacol Exp Ther 1988 247: 143-149. [Abstract] [PDF]  

U Agnarsson, T Tajima, and AJ Pappano

Carbachol depolarizes and accelerates pacemaker activity in the sinoatrial node of chicks treated with pertussis toxin
J Pharmacol Exp Ther 1988 247: 150-155. [Abstract] [PDF]  

JJ Liccione and MD Maines

Selective vulnerability of glutathione metabolism and cellular defense mechanisms in rat striatum to manganese
J Pharmacol Exp Ther 1988 247: 156-161. [Abstract] [PDF]  

GD Olsen, TM Cline, and KM Sommer

Comparison of chronic morphine and placebo infusion in late gestation fetal lambs: effect upon survival and breathing movements [published erratum appears in J Pharmacol Exp Ther 1989 Mar;248(3):1343]
J Pharmacol Exp Ther 1988 247: 162-168. [Abstract] [PDF]  

E Sanders-Bush and M Breeding

Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus
J Pharmacol Exp Ther 1988 247: 169-173. [Abstract] [PDF]  

MW Dudley, BW Siegel, AM Ogden, and DR McCarty

A low dose of xylamine produces sustained and selective decreases in rat brain norepinephrine without evidence of neuronal degeneration
J Pharmacol Exp Ther 1988 247: 174-179. [Abstract] [PDF]  

PK Sonsalla, L Manzino, and RE Heikkila

Interactions of D1 and D2 dopamine receptors on the ipsilateral vs. contralateral side in rats with unilateral lesions of the dopaminergic nigrostriatal pathway
J Pharmacol Exp Ther 1988 247: 180-185. [Abstract] [PDF]  

EH Ohlstein, LI Kruse, M Ezekiel, and RN Willette

Further characterization of the cardiovascular effects of the dopamine beta-hydroxylase inhibitor SK&F 102698 in conscious hypertensive rats
J Pharmacol Exp Ther 1988 247: 186-195. [Abstract] [PDF]  

G Jagadeesh and RC Deth

Phorbol ester-induced modulation of agonist binding to alpha-1 adrenergic receptors in bovine aortic membranes
J Pharmacol Exp Ther 1988 247: 196-202. [Abstract] [PDF]  

LJ Lee, JA Cook, and DE Smith

Renal transport kinetics of chlorothiazide in the isolated perfused rat kidney
J Pharmacol Exp Ther 1988 247: 203-208. [Abstract] [PDF]  

BJ Undem, PT Peachell, and LM Lichtenstein

Isoproterenol-induced inhibition of immunoglobulin E-mediated release of histamine and arachidonic acid metabolites from the human lung mast cell
J Pharmacol Exp Ther 1988 247: 209-217. [Abstract] [PDF]  

JA Warner, LM Lichtenstein, and DW Jr MacGlashan

Effects of a specific inhibitor of the 5-lipoxygenase pathway on mediator release from human basophils and mast cells
J Pharmacol Exp Ther 1988 247: 218-222. [Abstract] [PDF]  

RK Hester

Functional importance of alpha adrenoceptor-mediated, D600-insensitive Ca++ entry in rabbit aorta
J Pharmacol Exp Ther 1988 247: 223-234. [Abstract] [PDF]  

K Inui, T Okano, H Maegawa, M Kato, M Takano, and R Hori

H+ coupled transport of p.o. cephalosporins via dipeptide carriers in rabbit intestinal brush-border membranes: difference of transport characteristics between cefixime and cephradine
J Pharmacol Exp Ther 1988 247: 235-241. [Abstract] [PDF]  

SV Otton, HK Crewe, MS Lennard, GT Tucker, and HF Woods

Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes
J Pharmacol Exp Ther 1988 247: 242-247. [Abstract] [PDF]  

G Suarez-Kurtz and GJ Kaczorowski

Effects of dichlorobenzamil on calcium currents in clonal GH3 pituitary cells
J Pharmacol Exp Ther 1988 247: 248-253. [Abstract] [PDF]  

V Lagente, ZB Fortes, J Garcia-Leme, and BB Vargaftig

PAF-acether and endotoxin display similar effects on rat mesenteric microvessels: inhibition by specific antagonists
J Pharmacol Exp Ther 1988 247: 254-261. [Abstract] [PDF]  

AW Obianime, SJ Hirst, and MM Dale

Interactions between phorbol esters and agents which increase cytosolic calcium in the guinea pig parenchymal strip: direct and indirect effects on the contractile response
J Pharmacol Exp Ther 1988 247: 262-270. [Abstract] [PDF]  

DW Rurak, SD Yoo, E Kwan, SM Taylor, KW Riggs, and JE Axelson

Effects of diphenhydramine in the fetal lamb after maternal or fetal administration
J Pharmacol Exp Ther 1988 247: 271-278. [Abstract] [PDF]  

MA Czuba, GW Mihaly, MS Ching, DJ Morgan, KJ Hardy, and RA Smallwood

Effects of gestational age on the disposition of propranolol in pregnant sheep
J Pharmacol Exp Ther 1988 247: 279-282. [Abstract] [PDF]  

A Mulsch, R Busse, S Liebau, and U Forstermann

LY 83583 interferes with the release of endothelium-derived relaxing factor and inhibits soluble guanylate cyclase
J Pharmacol Exp Ther 1988 247: 283-288. [Abstract] [PDF]  

IB Linden, E Nissinen, E Etemadzadeh, S Kaakkola, P Mannisto, and P Pohto

Favorable effect of catechol-O-methyltransferase inhibition by OR-462 in experimental models of Parkinson's disease
J Pharmacol Exp Ther 1988 247: 289-293. [Abstract] [PDF]  

L Beani, C Bianchi, S Tanganelli, T Antonelli, M Simonato, and S Rando

Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs
J Pharmacol Exp Ther 1988 247: 294-301. [Abstract] [PDF]  

T Katsuragi, T Tokunaga, K Miyamoto, L Kuratomi, and T Furukawa

Norepinephrine and adenosine triphosphate release in different ratio from guinea pig vas deferens by high potassium chloride, ouabain and monensin
J Pharmacol Exp Ther 1988 247: 302-308. [Abstract] [PDF]  

T Dennis, A Dubois, J Benavides, and B Scatton

Distribution of central omega 1 (benzodiazepine1) and omega 2 (benzodiazepine2) receptor subtypes in the monkey and human brain. An autoradiographic study with [3H]flunitrazepam and the omega 1 selective ligand [3H]zolpidem
J Pharmacol Exp Ther 1988 247: 309-322. [Abstract] [PDF]  

SM de Morais and PG Wells

Deficiency in bilirubin UDP-glucuronyl transferase as a genetic determinant of acetaminophen toxicity
J Pharmacol Exp Ther 1988 247: 323-331. [Abstract] [PDF]  

D Bouhassira, L Villanueva, and D Le Bars

Intracerebroventricular morphine decreases descending inhibitions acting on lumbar dorsal horn neuronal activities related to pain in the rat
J Pharmacol Exp Ther 1988 247: 332-342. [Abstract] [PDF]  

KJ Nicklaus, P McGonigle, and PB Molinoff

[3H]SCH 23390 labels both dopamine-1 and 5-hydroxytryptamine1c receptors in the choroid plexus
J Pharmacol Exp Ther 1988 247: 343-348. [Abstract] [PDF]  

PD Holohan, PP Sokol, CR Ross, R Coulson, ME Trimble, DA Laska, and PD Williams

Gentamicin-induced increases in cytosolic calcium in pig kidney cells (LLC-PK1)
J Pharmacol Exp Ther 1988 247: 349-354. [Abstract] [PDF]  

RF Cox, JL Neumeyer, and BL Waszczak

Effects of N-n-propylnorapomorphine enantiomers on single unit activity of substantia nigra pars compacta and ventral tegmental area dopamine neurons
J Pharmacol Exp Ther 1988 247: 355-362. [Abstract] [PDF]  

G Matera, JA Cook, RA Hennigar, GE Tempel, WC Wise, TD Oglesby, and PV Halushka

Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat
J Pharmacol Exp Ther 1988 247: 363-371. [Abstract] [PDF]  

DJ Hinman and HH Szeto

Cholinergic influences on sleep-wake patterns and breathing movements in the fetus
J Pharmacol Exp Ther 1988 247: 372-378. [Abstract] [PDF]  

GA Ordway, C Gambarana, and A Frazer

Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol
J Pharmacol Exp Ther 1988 247: 379-389. [Abstract] [PDF]  

N Mahy, M Woolkalis, D Manning, and T Reisine

Characteristics of somatostatin desensitization in the pituitary tumor cell line AtT-20
J Pharmacol Exp Ther 1988 247: 390-396. [Abstract] [PDF]  

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