ARTICLES:

TE Jr Tenner, J Young, BJ Riker, and S Ramanadham

Nonspecific supersensitivity induced by reserpine in guinea pig cardiac ventricle tissue
J Pharmacol Exp Ther 1988 246: 1-6. [Abstract] [PDF]  

DR Rutledge, JA Pieper, and DM Mirvis

Effects of chronic phenobarbital on verapamil disposition in humans
J Pharmacol Exp Ther 1988 246: 7-13. [Abstract] [PDF]  

TJ Cicero, ER Meyer, BT Miller, and RD Bell

Age-related differences in the sensitivity of serum luteinizing hormone to prototypic mu, kappa and delta opiate agonists and antagonists
J Pharmacol Exp Ther 1988 246: 14-20. [Abstract] [PDF]  

RR Griffiths and PP Woodson

Reinforcing effects of caffeine in humans
J Pharmacol Exp Ther 1988 246: 21-29. [Abstract] [PDF]  

AA Alousi, AM Grant, PD Allen, and ED Pagani

Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts
J Pharmacol Exp Ther 1988 246: 30-37. [Abstract] [PDF]  

JM O'Donnell

Psychopharmacological consequences of activation of beta adrenergic receptors by SOM-1122
J Pharmacol Exp Ther 1988 246: 38-46. [Abstract] [PDF]  

BJ Undem and GK 3d Adams

An analysis of the functional interactions of selected contractile agonists in the guinea pig isolated trachea
J Pharmacol Exp Ther 1988 246: 47-53. [Abstract] [PDF]  

S Connors and M Vore

Coregulation of C3-hydroxyl versus C17-hydroxyl glucuronidation of beta- estradiol in pregnancy and after treatment with phenobarbital or ethinyl-estradiol
J Pharmacol Exp Ther 1988 246: 54-59. [Abstract] [PDF]  

GM Rubanyi, U Hoeffner, A Schwartz, and PM Vanhoutte

Stereoselective effect of diltiazem on endothelium-dependent relaxations in canine femoral arteries
J Pharmacol Exp Ther 1988 246: 60-64. [Abstract] [PDF]  

J Lehmann, AJ Hutchison, SE McPherson, C Mondadori, M Schmutz, CM Sinton, C Tsai, DE Murphy, DJ Steel, and M Williams

CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist
J Pharmacol Exp Ther 1988 246: 65-75. [Abstract] [PDF]  

JL Katz

Effects of drugs on stimulus control of behavior. III. Analysis of effects of pentobarbital and d-amphetamine
J Pharmacol Exp Ther 1988 246: 76-83. [Abstract] [PDF]  

DA Cory-Slechta

Mobilization of lead over the course of DMSA chelation therapy and long- term efficacy
J Pharmacol Exp Ther 1988 246: 84-91. [Abstract] [PDF]  

RL Spencer, VJ Hruby, and TF Burks

Body temperature response profiles for selective mu, delta and kappa opioid agonists in restrained and unrestrained rats
J Pharmacol Exp Ther 1988 246: 92-101. [Abstract] [PDF]  

CF Lundergan, TM Fitzpatrick, JC Rose, PW Ramwell, and PA Kot

Effect of cyclooxygenase inhibition on the pulmonary vasodilator response to furosemide
J Pharmacol Exp Ther 1988 246: 102-106. [Abstract] [PDF]  

O Yu, TH Chiu, and HC Rosenberg

Modulation of GABA-gated chloride ion flux in rat brain by acute and chronic benzodiazepine administration
J Pharmacol Exp Ther 1988 246: 107-113. [Abstract] [PDF]  

RS Mansbach, C Harrod, SM Hoffmann, MA Nader, Z Lei, JM Witkin, and JE Barrett

Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding
J Pharmacol Exp Ther 1988 246: 114-120. [Abstract] [PDF]  

CN Nair

Proton gradient independent organic cation transport by HeLa cells
J Pharmacol Exp Ther 1988 246: 121-124. [Abstract] [PDF]  

RN Friedman, GD Bittner, and JA Blundon

Electrophysiological and behavioral effects of ethanol on crayfish
J Pharmacol Exp Ther 1988 246: 125-131. [Abstract] [PDF]  

DS Louie, HT Chen, and C Owyang

Inhibition of exocrine pancreatic secretion by opiates is mediated by suppression of cholinergic transmission: characterization of receptor subtypes
J Pharmacol Exp Ther 1988 246: 132-136. [Abstract] [PDF]  

S Rothman

Noncompetitive N-methyl-D-aspartate antagonists affect multiple ionic currents
J Pharmacol Exp Ther 1988 246: 137-142. [Abstract] [PDF]  

SA Chow, DE Rickert, and LJ Fischer

Evidence that drug metabolites are involved in cyproheptadine-induced loss of pancreatic insulin
J Pharmacol Exp Ther 1988 246: 143-149. [Abstract] [PDF]  

UM Joshi, PR Kodavanti, B Coudert, TM Dwyer, and HM Mehendale

Types of interaction of amphiphilic drugs with phospholipid vesicles
J Pharmacol Exp Ther 1988 246: 150-157. [Abstract] [PDF]  

AL Morrow, PD Suzdak, JW Karanian, and SM Paul

Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes
J Pharmacol Exp Ther 1988 246: 158-164. [Abstract] [PDF]  

M Yasuhara and G Levy

Kinetics of drug action in disease states. XXVII. Effect of experimental renal failure on the pharmacodynamics of zoxazolamine and chlorzoxazone
J Pharmacol Exp Ther 1988 246: 165-169. [Abstract] [PDF]  

LG Miller, DJ Greenblatt, JG Barnhill, and RI Shader

Chronic benzodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gamma-aminobutyric acidA receptor function
J Pharmacol Exp Ther 1988 246: 170-176. [Abstract] [PDF]  

LG Miller, DJ Greenblatt, RB Roy, WR Summer, and RI Shader

Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function
J Pharmacol Exp Ther 1988 246: 177-182. [Abstract] [PDF]  

AF DeFelice and A Brousseau

Natriuretic and vasodilating activities of intrarenally administered atriopeptin II, substance P and bradykinin in the dog
J Pharmacol Exp Ther 1988 246: 183-188. [Abstract] [PDF]  

DA Twombly, M Yoshii, and T Narahashi

Mechanisms of calcium channel block by phenytoin
J Pharmacol Exp Ther 1988 246: 189-195. [Abstract] [PDF]  

RR Matsumoto, KH Brinsfield, RL Patrick, and JM Walker

Rotational behavior mediated by dopaminergic and nondopaminergic mechanisms after intranigral microinjection of specific mu, delta and kappa opioid agonists
J Pharmacol Exp Ther 1988 246: 196-203. [Abstract] [PDF]  

JD Winkler, HM Sarau, JJ Foley, S Mong, and ST Crooke

Leukotriene B4-induced homologous desensitization of calcium mobilization and phosphoinositide metabolism in U-937 cells
J Pharmacol Exp Ther 1988 246: 204-210. [Abstract] [PDF]  

GJ Trachte

Adrenergic nerves mediate angiotensin-induced prostaglandin release in the rabbit vas deferens
J Pharmacol Exp Ther 1988 246: 211-217. [Abstract] [PDF]  

LJ Ignarro, GM Buga, RE Byrns, KS Wood, and G Chaudhuri

Endothelium-derived relaxing factor and nitric oxide possess identical pharmacologic properties as relaxants of bovine arterial and venous smooth muscle
J Pharmacol Exp Ther 1988 246: 218-226. [Abstract] [PDF]  

SH Pollock, HH Herman, LC Fowler, AS Edwards, CO Evans, and SW May

Demonstration of the antihypertensive activity of phenyl-2-aminoethyl selenide
J Pharmacol Exp Ther 1988 246: 227-234. [Abstract] [PDF]  

V Elharrar

Recovery from use-dependent block of Vmax and restitution of action potential duration in canine cardiac Purkinje fibers
J Pharmacol Exp Ther 1988 246: 235-242. [Abstract] [PDF]  

VH Sethy and JW Francis

Regulation of brain acetylcholine concentration by muscarinic receptors
J Pharmacol Exp Ther 1988 246: 243-248. [Abstract] [PDF]  

IC Medgett and RR Jr Ruffolo

Alpha adrenoceptor-mediated vasoconstriction in rat hindlimb: innervated alpha-2 adrenoceptors in the saphenous arterial bed
J Pharmacol Exp Ther 1988 246: 249-254. [Abstract] [PDF]  

AE Takemori, BY Ho, JS Naeseth, and PS Portoghese

Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays
J Pharmacol Exp Ther 1988 246: 255-258. [Abstract] [PDF]  

PF Vonvoigtlander and RA Lewis

Analgesic and mechanistic evaluation of spiradoline, a potent kappa opioid
J Pharmacol Exp Ther 1988 246: 259-262. [Abstract] [PDF]  

GJ Grover, PG Sleph, and CS Parham

Effect of diltiazem on infarct size, reperfusion flow and flow reserve: the effect of timing of treatment
J Pharmacol Exp Ther 1988 246: 263-269. [Abstract] [PDF]  

GL Diamond, JM Klotzbach, and JR Stewart

Complexing activity of 2,3-dimercapto-1-propanesulfonate and its disulfide auto-oxidation product in rat kidney
J Pharmacol Exp Ther 1988 246: 270-274. [Abstract] [PDF]  

HE Shannon, TJ Hagen, F Guzman, and JA Cook

Beta-carbolines as antagonists of the discriminative stimulus effects of diazepam in rats
J Pharmacol Exp Ther 1988 246: 275-281. [Abstract] [PDF]  

LL Werling, A Frattali, PS Portoghese, AE Takemori, and BM Cox

Kappa receptor regulation of dopamine release from striatum and cortex of rats and guinea pigs
J Pharmacol Exp Ther 1988 246: 282-286. [Abstract] [PDF]  

F Delaini, N Perico, M Tagliaferri, C Lupini, O Patino, G Remuzzi, and S Garattini

Tertatolol ameliorates renal function in rats with chronic renal failure
J Pharmacol Exp Ther 1988 246: 287-293. [Abstract] [PDF]  

K Sato, H Ozaki, and H Karaki

Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator fura 2
J Pharmacol Exp Ther 1988 246: 294-300. [Abstract] [PDF]  

P Gresele, D Blockmans, H Deckmyn, and J Vermylen

Adenylate cyclase activation determines the effect of thromboxane synthase inhibitors on platelet aggregation in vitro. Comparison of platelets from responders and nonresponders
J Pharmacol Exp Ther 1988 246: 301-307. [Abstract] [PDF]  

CA Maggi, M Parlani, M Astolfi, P Santicioli, P Rovero, L Abelli, V Somma, S Giuliani, D Regoli, and R Patacchini

Neurokinin receptors in the rat lower urinary tract
J Pharmacol Exp Ther 1988 246: 308-315. [Abstract] [PDF]  

RA Bassani and S de Moraes

Effects of repeated footshock stress on the chronotropic responsiveness of the isolated pacemaker of the rat: role of beta-2 adrenoceptors
J Pharmacol Exp Ther 1988 246: 316-321. [Abstract] [PDF]  

S Giuliani, CA Maggi, P Rovero, and A Meli

Neurokinins induce a relaxation of the rat duodenum "in vivo" by activating postganglionic sympathetic elements in prevertebral ganglia: involvement of an NK-2 type of neurokinin receptor
J Pharmacol Exp Ther 1988 246: 322-327. [Abstract] [PDF]  

A Wellstein, GG Belz, and D Palm

Beta adrenoceptor subtype binding activity in plasma and beta blockade by propranolol and beta-1 selective bisoprolol in humans. Evaluation with Schild-plots
J Pharmacol Exp Ther 1988 246: 328-337. [Abstract] [PDF]  

I Tamai, A Tsuji, and Y Kin

Carrier-mediated transport of cefixime, a new cephalosporin antibiotic, via an organic anion transport system in the rat renal brush-border membrane
J Pharmacol Exp Ther 1988 246: 338-344. [Abstract] [PDF]  

JO Karlsson, H Elwing, N Grundstrom, and RG Andersson

Pronounced supersensitivity of postjunctional alpha adrenoceptors after denervation of fish melanophores
J Pharmacol Exp Ther 1988 246: 345-351. [Abstract] [PDF]  

JW Downie and GJ Bialik

Evidence for a spinal site of action of clonidine on somatic and viscerosomatic reflex activity evoked on the pudendal nerve in cats
J Pharmacol Exp Ther 1988 246: 352-358. [Abstract] [PDF]  

Y Chaput and C de Montigny

Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5- hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system
J Pharmacol Exp Ther 1988 246: 359-370. [Abstract] [PDF]  

J Dingemanse, M Polhuijs, and M Danhof

Altered pharmacokinetic-pharmacodynamic relationship of heptabarbital in experimental renal failure in rats
J Pharmacol Exp Ther 1988 246: 371-376. [Abstract] [PDF]  

RC Levi and G Alloatti

Histamine modulates calcium current in guinea pig ventricular myocytes
J Pharmacol Exp Ther 1988 246: 377-383. [Abstract] [PDF]  

P Molenaar, CR Jones, LR McMartin, and RJ Summers

Autoradiographic localization and densitometric analysis of beta-1 and beta-2 adrenoceptors in the canine left anterior descending coronary artery
J Pharmacol Exp Ther 1988 246: 384-393. [Abstract] [PDF]  

JP O'Callaghan and DB Miller

Acute exposure of the neonatal rat to tributyltin results in decreases in biochemical indicators of synaptogenesis and myelinogenesis
J Pharmacol Exp Ther 1988 246: 394-402. [Abstract] [PDF]  

SJ Li, SP Sivam, JF McGinty, HK Jiang, J Douglass, L Calavetta, and JS Hong

Regulation of the metabolism of striatal dynorphin by the dopaminergic system
J Pharmacol Exp Ther 1988 246: 403-408. [Abstract] [PDF]  

PM Lippiello and KG Fernandes

Identification of putative high affinity nicotinic receptors on cultured cortical neurons
J Pharmacol Exp Ther 1988 246: 409-416. [Abstract] [PDF]  

ERRATUM
J Pharmacol Exp Ther 1988 246: 416-417. [Abstract] [PDF]  

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