ARTICLES:

KD Meisheri, LA Cipkus, and CJ Taylor

Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability
J Pharmacol Exp Ther 1988 245: 751-760. [Abstract] [PDF]  

IS Hoffmann, RK Talmaciu, CP Ferro, and LX Cubeddu

Sustained high release at rapid stimulation rates and reduced functional autoreceptors characterize prefrontal cortex dopamine terminals
J Pharmacol Exp Ther 1988 245: 761-772. [Abstract] [PDF]  

G Scholtysik, Y Imoto, A Yatani, and AM Brown

5-Hydroxytryptamine antagonist ICS 205-930 blocks cardiac potassium, sodium and calcium currents
J Pharmacol Exp Ther 1988 245: 773-778. [Abstract] [PDF]  

KP Patel and PG Schmid

Vasopressin inhibits sympathetic ganglionic transmission but potentiates sympathetic neuroeffector responses in hindlimb vasculature of rabbits
J Pharmacol Exp Ther 1988 245: 779-785. [Abstract] [PDF]  

A Hedberg, SE Hall, ML Ogletree, DN Harris, and EC Liu

Characterization of [5,6-3H]SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets
J Pharmacol Exp Ther 1988 245: 786-792. [Abstract] [PDF]  

VK Lamba-Kanwal, A Hamada, A Adejare, MT Clark, DD Miller, and PN Patil

Activation of alpha-1 adrenoreceptors of rat aorta by analogs of imidazoline [published erratum appears in J Pharmacol Exp Ther 1988 Sep;246(3):1201]
J Pharmacol Exp Ther 1988 245: 793-797. [Abstract] [PDF]  

RN Daly, PB Goldberg, and J Roberts

Effects of age on neurotransmission at the cardiac sympathetic neuroeffector junction
J Pharmacol Exp Ther 1988 245: 798-803. [Abstract] [PDF]  

TD Bjornsson, DE Schneider, and AR Hecht

Effects of N-deacetylation and N-desulfation of heparin on its anticoagulant activity and in vivo disposition
J Pharmacol Exp Ther 1988 245: 804-808. [Abstract] [PDF]  

MG Wientjes and G Levy

Nonlinear pharmacokinetics of aspirin in rats
J Pharmacol Exp Ther 1988 245: 809-815. [Abstract] [PDF]  

DR Jones, SD Hall, EK Jackson, RA Branch, and GR Wilkinson

Brain uptake of benzodiazepines: effects of lipophilicity and plasma protein binding
J Pharmacol Exp Ther 1988 245: 816-822. [Abstract] [PDF]  

Y Miyamoto, DF Balkovetz, V Ganapathy, T Iwatsubo, M Hanano, and FH Leibach

Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit
J Pharmacol Exp Ther 1988 245: 823-828. [Abstract] [PDF]  

RE Chipkin, JG Berger, W Billard, LC Iorio, R Chapman, and A Barnett

Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic
J Pharmacol Exp Ther 1988 245: 829-838. [Abstract] [PDF]  

FA Fitzpatrick and CF Lawson

Myotropic activity of leukotriene B4 on lung parenchyma strips is not necessarily attributable to thromboxane A2 release
J Pharmacol Exp Ther 1988 245: 839-844. [Abstract] [PDF]  

RG Knodell, RK Dubey, GR Wilkinson, and FP Guengerich

Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation
J Pharmacol Exp Ther 1988 245: 845-849. [Abstract] [PDF]  

BA Berkowitz, AJ Arleth, CP Sung, LI Kruse, WE Jr DeWolf, and EH Ohlstein

Effects of the novel dopamine beta-hydroxylase inhibitor SK&F 102698 on catecholamines and blood pressure in spontaneously hypertensive rats
J Pharmacol Exp Ther 1988 245: 850-857. [Abstract] [PDF]  

H Rollema, WG Kuhr, G Kranenborg, J De Vries, and C Van den Berg

MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis
J Pharmacol Exp Ther 1988 245: 858-866. [Abstract] [PDF]  

LL Simpson

Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins
J Pharmacol Exp Ther 1988 245: 867-872. [Abstract] [PDF]  

JF Jr Nash, HY Meltzer, and GA Gudelsky

Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine
J Pharmacol Exp Ther 1988 245: 873-879. [Abstract] [PDF]  

PD Suzdak, SM Paul, and JN Crawley

Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-induced intoxication in the rat
J Pharmacol Exp Ther 1988 245: 880-886. [Abstract] [PDF]  

SA Rogers, KC Gale, JF Newton, JG Dent, and TB Leonard

Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity
J Pharmacol Exp Ther 1988 245: 887-894. [Abstract] [PDF]  

NK Mello, JH Mendelson, MP Bree, and A Skupny

Alcohol effects on naloxone-stimulated luteinizing hormone, follicle- stimulating hormone and prolactin plasma levels in female rhesus monkeys
J Pharmacol Exp Ther 1988 245: 895-904. [Abstract] [PDF]  

RE Solomon and GF Gebhart

Mechanisms of effects of intrathecal serotonin on nociception and blood pressure in rats
J Pharmacol Exp Ther 1988 245: 905-912. [Abstract] [PDF]  

HU Bryant, EW Bernton, and JW Holaday

Morphine pellet-induced immunomodulation in mice: temporal relationships
J Pharmacol Exp Ther 1988 245: 913-920. [Abstract] [PDF]  

JA Near, JC Bigelow, and RM Wightman

Comparison of uptake of dopamine in rat striatal chopped tissue and synaptosomes
J Pharmacol Exp Ther 1988 245: 921-927. [Abstract] [PDF]  

SD Provan and RA Yokel

Aluminum uptake by the in situ rat gut preparation
J Pharmacol Exp Ther 1988 245: 928-931. [Abstract] [PDF]  

BR Lindgren, N Grundstrom, and RG Andersson

Effects of an alpha-2 adrenoceptor agonist on angiotensin converting enzyme inhibitor-induced hypotension and potentiated allergen-evoked inflammatory skin responses
J Pharmacol Exp Ther 1988 245: 932-935. [Abstract] [PDF]  

T Nakane, G Tsujimoto, K Hashimoto, and S Chiba

Beta adrenoceptors in the canine large coronary arteries: beta-1 adrenoceptors predominate in vasodilation
J Pharmacol Exp Ther 1988 245: 936-943. [Abstract] [PDF]  

B Valenta, H Drobny, and EA Singer

Presynaptic autoinhibition of central noradrenaline release in vitro: operational characteristics and effects of drugs acting at alpha-2 adrenoceptors in the presence of uptake inhibition
J Pharmacol Exp Ther 1988 245: 944-949. [Abstract] [PDF]  

B Jackson, RB Cubela, and CI Johnston

Inhibition of tissue angiotensin converting enzyme by perindopril: in vivo assessment in the rat using radioinhibitor binding displacement
J Pharmacol Exp Ther 1988 245: 950-955. [Abstract] [PDF]  

JS Leeder, M Cannon, A Nakhooda, and SP Spielberg

Drug metabolite toxicity assessed in human lymphocytes with a purified, reconstituted cytochrome P-450 system
J Pharmacol Exp Ther 1988 245: 956-962. [Abstract] [PDF]  

A Eschalier, J Fialip, O Varoquaux, MC Makambila, H Marty, and P Bastide

Pharmacokinetic patterns of repeated administration of antidepressants in animals. I. Implications for antinociceptive action of clomipramine in mice
J Pharmacol Exp Ther 1988 245: 963-968. [Abstract] [PDF]  

W Koek, JH Woods, and GD Winger

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
J Pharmacol Exp Ther 1988 245: 969-974. [Abstract] [PDF]  

M Gascon-Barre, PM Huet, G St-Onge-Brault, A Brault, and I Kassissia

Liver extraction of vitamin D3 is independent of its hepatic venous or arterial route of delivery. Studies in isolated-perfused rat liver preparations
J Pharmacol Exp Ther 1988 245: 975-981. [Abstract] [PDF]  

H Mitsushio, M Takashima, N Mataga, and M Toru

Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders
J Pharmacol Exp Ther 1988 245: 982-989. [Abstract] [PDF]  

T Okamoto, K Kurahashi, and M Fujiwara

Cholinergic transmission in the superior cervical ganglion reinnervated by peripheral vagal stump cut below the nodose ganglion in cats
J Pharmacol Exp Ther 1988 245: 990-994. [Abstract] [PDF]  

JE Gairin, R Gout, JC Meunier, and J Cros

[D-Pro10]-dynorphin(1-11) is a kappa-selective opioid analgesic in mice
J Pharmacol Exp Ther 1988 245: 995-1001. [Abstract] [PDF]  

EE Daniel, F Kostolanska, HD Allescher, S Ahmad, and JE Fox

Local actions of trimebutine maleate in canine small intestine
J Pharmacol Exp Ther 1988 245: 1002-1009. [Abstract] [PDF]  

AJ Kaumann and M Frenken

ICI 169,369 is both a competitive antagonist and an allosteric activator of the arterial 5-hydroxytryptamine2 receptor system
J Pharmacol Exp Ther 1988 245: 1010-1015. [Abstract] [PDF]  

JC Wanstall and SR O'Donnell

Inhibition of norepinephrine contractions by diltiazem on aorta and pulmonary artery from young and aged rats: influence of alpha- adrenoceptor reserve
J Pharmacol Exp Ther 1988 245: 1016-1020. [Abstract] [PDF]  

SC Mah, JR Opperman, HP Baum, and KG Hofbauer

Biologic response to chronic blockade of vasopressin receptors in Sprague-Dawley rats
J Pharmacol Exp Ther 1988 245: 1021-1027. [Abstract] [PDF]  

SC Mah and KG Hofbauer

Evaluation of the pharmacologic properties of a vasopressin antagonist in Brattleboro rats
J Pharmacol Exp Ther 1988 245: 1028-1032. [Abstract] [PDF]  

J Benavides, B Peny, A Dubois, G Perrault, E Morel, B Zivkovic, and B Scatton

In vivo interaction of zolpidem with central benzodiazepine (BZD) binding sites (as labeled by [3H]Ro 15-1788) in the mouse brain. Preferential affinity of zolpidem for the omega 1 (BZD1) subtype
J Pharmacol Exp Ther 1988 245: 1033-1041. [Abstract] [PDF]  

S Phaneuf, P Berta, LP Peuch, J Haiech, and JC Cavadore

Phorbol ester modulation of cyclic AMP accumulation in a primary culture of rat aortic smooth muscle cells
J Pharmacol Exp Ther 1988 245: 1042-1047. [Abstract] [PDF]  

SG Gilbert, DC Rice, KR Reuhl, and B Stavric

Adverse pregnancy outcome in the monkey (Macaca fascicularis) after chronic caffeine exposure
J Pharmacol Exp Ther 1988 245: 1048-1053. [Abstract] [PDF]  

BM Tune, RK Sibley, and CY Hsu

The mitochondrial respiratory toxicity of cephalosporin antibiotics. An inhibitory effect on substrate uptake
J Pharmacol Exp Ther 1988 245: 1054-1059. [Abstract] [PDF]  

SM Shreeve

Classification of bovine aortic alpha-1 adrenoceptors by the criteria of ligand affinity and molecular mass
J Pharmacol Exp Ther 1988 245: 1060-1067. [Abstract] [PDF]  

JG Granneman and RG MacKenzie

Neural modulation of the stimulatory regulatory protein of adenylate cyclase in rat brown adipose tissue
J Pharmacol Exp Ther 1988 245: 1068-1074. [Abstract] [PDF]  

JG Granneman

Norepinephrine infusions increase adenylate cyclase responsiveness in brown adipose tissue
J Pharmacol Exp Ther 1988 245: 1075-1080. [Abstract] [PDF]  

MP Goldberg, V Viseskul, and DW Choi

Phencyclidine receptor ligands attenuate cortical neuronal injury after N-methyl-D-aspartate exposure or hypoxia
J Pharmacol Exp Ther 1988 245: 1081-1087. [Abstract] [PDF]  

SM Spaethe, MS Freed, K De Schryver-Kecskemeti, JB Lefkowith, and P Needleman

Essential fatty acid deficiency reduces the inflammatory cell invasion in rabbit hydronephrosis resulting in suppression of the exaggerated eicosanoid production
J Pharmacol Exp Ther 1988 245: 1088-1094. [Abstract] [PDF]  

PW Kalivas and B Weber

Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine
J Pharmacol Exp Ther 1988 245: 1095-1102. [Abstract] [PDF]  

JG Kenna, H Satoh, DD Christ, and LR Pohl

Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane
J Pharmacol Exp Ther 1988 245: 1103-1109. [Abstract] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.