ARTICLES:

LC Daniell and RA Harris

Neuronal intracellular calcium concentrations are altered by anesthetics: relationship to membrane fluidization
J Pharmacol Exp Ther 1988 245: 1-7. [Abstract] [PDF]  

CL Williams, RJ Bodnar, JE Clark, EF Hahn, TF Burks, and GW Pasternak

Irreversible opiate agonists and antagonists. IV. Analgesic actions of 14-hydroxydihydromorphinone hydrazones
J Pharmacol Exp Ther 1988 245: 8-12. [Abstract] [PDF]  

JL Vaught, JR Mathiasen, and RB Raffa

Examination of the involvement of supraspinal and spinal mu and delta opioid receptors in analgesia using the mu receptor deficient CXBK mouse
J Pharmacol Exp Ther 1988 245: 13-16. [Abstract] [PDF]  

MW Emmett-Oglesby, TS Shippenberg, and A Herz

Tolerance and cross-tolerance to the discriminative stimulus properties of fentanyl and morphine
J Pharmacol Exp Ther 1988 245: 17-23. [Abstract] [PDF]  

SJ Donohue, RE Stitzel, and RJ Head

Time course of changes in the norepinephrine content of tissues from spontaneously hypertensive and Wistar Kyoto rats
J Pharmacol Exp Ther 1988 245: 24-31. [Abstract] [PDF]  

BV Clineschmidt, DJ Pettibone, VJ Lotti, HB Hucker, BM Sweeney, DR Reiss, EV Lis, JR Huff, and J Vacca

A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066
J Pharmacol Exp Ther 1988 245: 32-40. [Abstract] [PDF]  

CJ Helke and ET Phillips

Thyrotropin-releasing hormone receptor activation in the spinal cord increases blood pressure and sympathetic tone to the vasculature and the adrenals
J Pharmacol Exp Ther 1988 245: 41-46. [Abstract] [PDF]  

RJ Secrest, EH Ohlstein, and BM Chapnick

Relationship between LTD4-induced endothelium-dependent vasomotor relaxation and cGMP
J Pharmacol Exp Ther 1988 245: 47-52. [Abstract] [PDF]  

Y Shirasaki, P Kolm, GA Nickols, and TJ Lee

Endothelial regulation of cyclic GMP and vascular responses in hypertension
J Pharmacol Exp Ther 1988 245: 53-58. [Abstract] [PDF]  

N Jaiswal and KU Malik

Prostaglandin synthesis elicited by cholinergic stimuli is mediated by activation of M2 muscarinic receptors in rabbit heart
J Pharmacol Exp Ther 1988 245: 59-66. [Abstract] [PDF]  

RE Purdy, GL Stupecky, and PR Coulombe

Further evidence for a homogeneous population of beta-1-adrenoceptors in bovine coronary artery
J Pharmacol Exp Ther 1988 245: 67-71. [Abstract] [PDF]  

BV Sastry, N Jaiswal, LK Owens, VE Janson, and RD Moore

2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase
J Pharmacol Exp Ther 1988 245: 72-80. [Abstract] [PDF]  

G Eisenhofer, TG Ropchak, IJ Kopin, and DS Goldstein

Release, metabolism and intraneuronal disposition of exogenous, endogenous and newly synthesized norepinephrine in the rat vas deferens
J Pharmacol Exp Ther 1988 245: 81-88. [Abstract] [PDF]  

CT Harker and PM Vanhoutte

Cooling the central ear artery of the rabbit: myogenic and adrenergic responses
J Pharmacol Exp Ther 1988 245: 89-93. [Abstract] [PDF]  

JA Nathanson

Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process
J Pharmacol Exp Ther 1988 245: 94-101. [Abstract] [PDF]  

TJ Rimele, RJ Sturm, LM Adams, DE Henry, RJ Heaslip, BM Weichman, and D Grimes

Interaction of neutrophils with vascular smooth muscle: identification of a neutrophil-derived relaxing factor
J Pharmacol Exp Ther 1988 245: 102-111. [Abstract] [PDF]  

SS Shetty and GB Weiss

Alterations in 28Mg distribution and movements in rabbit aortic smooth muscle
J Pharmacol Exp Ther 1988 245: 112-119. [Abstract] [PDF]  

R Chandrasekhar, HM Huang, and GY Sun

Alterations in rat brain polyphosphoinositide metabolism due to acute ethanol administration
J Pharmacol Exp Ther 1988 245: 120-123. [Abstract] [PDF]  

DA Robertson, DY Wang, CO Lee, and R Levi

Negative inotropic effect of platelet-activating factor: association with a decrease in intracellular sodium activity [published erratum appears in J Pharmacol Exp Ther 1988 Sep;246(3):1201]
J Pharmacol Exp Ther 1988 245: 124-128. [Abstract] [PDF]  

KE Thummel, JT Slattery, and SD Nelson

Mechanism by which ethanol diminishes the hepatotoxicity of acetaminophen
J Pharmacol Exp Ther 1988 245: 129-136. [Abstract] [PDF]  

GN Ervin and BR Cooper

Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs
J Pharmacol Exp Ther 1988 245: 137-146. [Abstract] [PDF]  

P Nencini, CE Johanson, and CR Schuster

Sensitization to kappa opioid mechanisms associated with tolerance to the anorectic effects of cathinone
J Pharmacol Exp Ther 1988 245: 147-154. [Abstract] [PDF]  

JF McElroy and JM O'Donnell

Discriminative stimulus properties of clenbuterol: evidence for beta adrenergic involvement
J Pharmacol Exp Ther 1988 245: 155-163. [Abstract] [PDF]  

T Suzuki, FR George, and RA Meisch

Differential establishment and maintenance of oral ethanol reinforced behavior in Lewis and Fischer 344 inbred rat strains
J Pharmacol Exp Ther 1988 245: 164-170. [Abstract] [PDF]  

RH Abhold and JW Harding

Metabolism of angiotensins II and III by membrane-bound peptidases from rat brain
J Pharmacol Exp Ther 1988 245: 171-177. [Abstract] [PDF]  

GE Schulze, DE McMillan, JR Bailey, A Scallet, SF Ali, W Jr Slikker, and MG Paule

Acute effects of delta-9-tetrahydrocannabinol in rhesus monkeys as measured by performance in a battery of complex operant tests
J Pharmacol Exp Ther 1988 245: 178-186. [Abstract] [PDF]  

F Lux, DA Brase, and WL Dewey

Differential effects of subcutaneous and intrathecal morphine administration on blood glucose in mice: comparison with intracerebroventricular administration
J Pharmacol Exp Ther 1988 245: 187-194. [Abstract] [PDF]  

C Severi, JR Grider, and GM Makhlouf

Identification of separate bombesin and substance P receptors on isolated muscle cells from canine gallbladder
J Pharmacol Exp Ther 1988 245: 195-198. [Abstract] [PDF]  

EM Parker and LX Cubeddu

Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding
J Pharmacol Exp Ther 1988 245: 199-210. [Abstract] [PDF]  

DP Brooks, PF Koster, CR Albrightson-Winslow, FL Stassen, WF Huffman, and LB Kinter

SK&F 105494 is a potent antidiuretic hormone antagonist in the rhesus monkey (Macaca mulatta)
J Pharmacol Exp Ther 1988 245: 211-215. [Abstract] [PDF]  

M Callaham, H Schumaker, and P Pentel

Phenytoin prophylaxis of cardiotoxicity in experimental amitriptyline poisoning
J Pharmacol Exp Ther 1988 245: 216-220. [Abstract] [PDF]  

LF McNicholas, WR Martin, JW Sloan, and E Wala

Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs
J Pharmacol Exp Ther 1988 245: 221-224. [Abstract] [PDF]  

T Reisine, HL Wang, and S Guild

Somatostatin inhibits cAMP-dependent and cAMP-independent calcium influx in the clonal pituitary tumor cell line AtT-20 through the same receptor population
J Pharmacol Exp Ther 1988 245: 225-231. [Abstract] [PDF]  

RJ Bache, DC Homans, JS Schwartz, and XZ Dai

Differences in the effects of alpha-1 adrenergic blockade with prazosin and indoramin on coronary blood flow during exercise
J Pharmacol Exp Ther 1988 245: 232-237. [Abstract] [PDF]  

JS Heyman, CL Williams, TF Burks, HI Mosberg, and F Porreca

Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine
J Pharmacol Exp Ther 1988 245: 238-243. [Abstract] [PDF]  

WR Milnor and A Sastre

Cholinergic receptors and contraction of smooth muscle in canine portal vein
J Pharmacol Exp Ther 1988 245: 244-249. [Abstract] [PDF]  

K Taniyama, S Hashimoto, S Hanada, and C Tanaka

Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gamma-aminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine
J Pharmacol Exp Ther 1988 245: 250-256. [Abstract] [PDF]  

A Imperato, G Tanda, R Frau, and G Di Chiara

Pharmacological profile of dopamine receptor agonists as studied by brain dialysis in behaving rats
J Pharmacol Exp Ther 1988 245: 257-264. [Abstract] [PDF]  

D Harland and MJ Brown

Effects of acute and chronic administration of idazoxan on blood pressure and plasma catecholamine concentrations of rats
J Pharmacol Exp Ther 1988 245: 265-273. [Abstract] [PDF]  

J Uetrecht, N Zahid, NH Shear, and WD Biggar

Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells
J Pharmacol Exp Ther 1988 245: 274-279. [Abstract] [PDF]  

E Klinge, S Alaranta, and NO Sjostrand

Pharmacological analysis of nicotinic relaxation of bovine retractor penis muscle
J Pharmacol Exp Ther 1988 245: 280-286. [Abstract] [PDF]  

MC Gambino, S Passaghe, ZM Chen, F Bucchi, G Gori, R Latini, G de Gaetano, and C Cerletti

Selectivity of oral aspirin as an inhibitor of platelet vs. vascular cyclooxygenase activity is reduced by portacaval shunt in rats
J Pharmacol Exp Ther 1988 245: 287-290. [Abstract] [PDF]  

SM Pond, JA Waschek, V Mahacha, RM Fielding, DJ Effeney, and TN Tozer

Nonlinear intestinal first-pass metabolism of salicylamide in dogs after portacaval transposition
J Pharmacol Exp Ther 1988 245: 291-293. [Abstract] [PDF]  

K Ohno, T Sakai, M Fukushima, S Narumiya, and M Fujiwara

Site and mechanism of growth inhibition by prostaglandins. IV. Effect of cyclopentenone prostaglandins on cell cycle progression of G1- enriched HeLa S3 cells
J Pharmacol Exp Ther 1988 245: 294-298. [Abstract] [PDF]  

A Baba, Y Nishiuchi, A Uemura, and H Iwata

Mechanism of excitatory amino acid-induced accumulation of cyclic AMP in hippocampal slices: role of extracellular chloride
J Pharmacol Exp Ther 1988 245: 299-304. [Abstract] [PDF]  

Y Hara, K Ichihara, and Y Abiko

MCl-176, a novel calcium channel blocker, attenuates the ischemic myocardial acidosis induced by coronary artery occlusion in dogs
J Pharmacol Exp Ther 1988 245: 305-310. [Abstract] [PDF]  

K Kushiku, Y Araki, T Furukawa, T Iwasa, N Inoue, and E Miyamoto

Increment of calmodulin in proportion to enhancement of non-nicotinic responses after preganglionic stimulation of the dog cardiac sympathetic ganglia
J Pharmacol Exp Ther 1988 245: 311-318. [Abstract] [PDF]  

SE Sherman, CW Loomis, B Milne, and FW Cervenko

Tolerance to intrathecal oxymetazoline-induced analgesia, with paradigm- dependent cross-tolerance to intrathecal morphine
J Pharmacol Exp Ther 1988 245: 319-326. [Abstract] [PDF]  

J Scholz, B Schaefer, W Schmitz, H Scholz, M Steinfath, M Lohse, U Schwabe, and J Puurunen

Alpha-1 adrenoceptor-mediated positive inotropic effect and inositol trisphosphate increase in mammalian heart
J Pharmacol Exp Ther 1988 245: 327-335. [Abstract] [PDF]  

H Nakamura, Y Seto, S Motoyoshi, T Kadokawa, and N Sunahara

Recombinant human tumor necrosis factor causes long-lasting and prostaglandin-mediated fever, with little tolerance, in rabbits
J Pharmacol Exp Ther 1988 245: 336-341. [Abstract] [PDF]  

RT McCabe, RW Olsen, JP Yezuita, and JK Wamsley

Osmotic shock: a method to eliminate endogenous gamma-aminobutyric acid and account for the influence on benzodiazepine binding affinity in autoradiographic studies
J Pharmacol Exp Ther 1988 245: 342-349. [Abstract] [PDF]  

VC Yu and W Sadee

Efficacy and tolerance of narcotic analgesics at the mu opioid receptor in differentiated human neuroblastoma cells
J Pharmacol Exp Ther 1988 245: 350-355. [Abstract] [PDF]  

D Bhaskaran and CR Freed

Changes in arterial blood pressure lead to baroreceptor-mediated changes in norepinephrine and 5-hydroxyindoleacetic acid in rat nucleus tractus solitarius
J Pharmacol Exp Ther 1988 245: 356-363. [Abstract] [PDF]  

LL Howell, J Bergman, and WH Morse

Effects of levorphanol and several kappa-selective opioids on respiration and behavior in rhesus monkeys
J Pharmacol Exp Ther 1988 245: 364-372. [Abstract] [PDF]  

PJ Gatti, KJ Hill, AM Da Silva, WP Norman, and RA Gillis

Central nervous system site of action for the hypotensive effect of clonidine in the cat
J Pharmacol Exp Ther 1988 245: 373-380. [Abstract] [PDF]  

W Spinelli, P Jr Danilo, and MR Rosen

Reduction of Vmax by QX-314 and benzocaine in neonatal and adult canine cardiac Purkinje fibers
J Pharmacol Exp Ther 1988 245: 381-387. [Abstract] [PDF]  

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