ARTICLES:

JE Shook, JT Pelton, PK Lemcke, F Porreca, VJ Hruby, and TF Burks

Mu opioid antagonist properties of a cyclic somatostatin octapeptide in vivo: identification of mu receptor-related functions
J Pharmacol Exp Ther 1987 242: 1-7. [Abstract] [PDF]  

H Bitterman, GR 3d Phillips, G Dragon, and AM Lefer

Potentiation of the protective effects of a converting enzyme inhibitor and a thromboxane synthetase inhibitor in hemorrhagic shock
J Pharmacol Exp Ther 1987 242: 8-14. [Abstract] [PDF]  

RA Cruciani, RA Lutz, PJ Munson, and D Rodbard

Naloxonazine effects on the interaction of enkephalin analogs with mu- 1, mu and delta opioid binding sites in rat brain membranes
J Pharmacol Exp Ther 1987 242: 15-20. [Abstract] [PDF]  

JA Van Loon and RM Weinshilboum

Human lymphocyte thiopurine methyltransferase pharmacogenetics: effect of phenotype on 6-mercaptopurine-induced inhibition of mitogen stimulation
J Pharmacol Exp Ther 1987 242: 21-26. [Abstract] [PDF]  

Z Gregus, AF Stein, and CD Klaassen

Effect of inhibition of gamma-glutamyltranspeptidase on biliary and urinary excretion of glutathione-derived thiols and methylmercury
J Pharmacol Exp Ther 1987 242: 27-32. [Abstract] [PDF]  

JD Leander, JC Hart, and RL Zerbe

Kappa agonist-induced diuresis: evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels
J Pharmacol Exp Ther 1987 242: 33-39. [Abstract] [PDF]  

JV Barnett, DS Segal, and R Kuczenski

Repeated amphetamine pretreatment alters the responsiveness of striatal dopamine-stimulated adenylate cyclase to amphetamine-induced desensitization
J Pharmacol Exp Ther 1987 242: 40-47. [Abstract] [PDF]  

PP De Deyn and RL Macdonald

CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture
J Pharmacol Exp Ther 1987 242: 48-55. [Abstract] [PDF]  

TE Nelson

Ryanodine: antithetical calcium channel effects in skeletal muscle sarcoplasmic reticulum
J Pharmacol Exp Ther 1987 242: 56-61. [Abstract] [PDF]  

RA Hahn and BR MacDonald

Primate myocardial and systemic hemodynamic responses to leukotriene D4: antagonism by LY171883
J Pharmacol Exp Ther 1987 242: 62-69. [Abstract] [PDF]  

SJ Moore, JC Norris, DA Walsh, and AS Hume

Antidotal use of methemoglobin forming cyanide antagonists in concurrent carbon monoxide/cyanide intoxication
J Pharmacol Exp Ther 1987 242: 70-73. [Abstract] [PDF]  

RP Shank, JF Gardocki, CR Schneider, JL Vaught, PE Setler, BE Maryanoff, and DF McComsey

Preclinical evaluation of McN-5707 as a potential antidepressant
J Pharmacol Exp Ther 1987 242: 74-84. [Abstract] [PDF]  

BP Fine, A Ty, N Lestrange, E Maher, and OR Levine

Diuretic-induced growth failure in rats and its reversal by sodium repletion
J Pharmacol Exp Ther 1987 242: 85-89. [Abstract] [PDF]  

S Wigdor and GL Wilcox

Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways
J Pharmacol Exp Ther 1987 242: 90-95. [Abstract] [PDF]  

SM Owens, WC Hardwick, and D Blackall

Phencyclidine pharmacokinetic scaling among species
J Pharmacol Exp Ther 1987 242: 96-101. [Abstract] [PDF]  

J Joselevitz-Goldman, ME Upsher, and HR Weiss

Effects of propranolol on regional O2 supply and O2 consumption in reperfused dog myocardium
J Pharmacol Exp Ther 1987 242: 102-107. [Abstract] [PDF]  

BM Clancy, R Osman, and S Maayani

Kinetics of competitive drug action at 5-hydroxytryptamine2 receptors in isolated rabbit aorta
J Pharmacol Exp Ther 1987 242: 108-114. [Abstract] [PDF]  

CA Altar, WC Boyar, E Oei, and PL Wood

Dopamine autoreceptors modulate the in vivo release of dopamine in the frontal, cingulate and entorhinal cortices
J Pharmacol Exp Ther 1987 242: 115-120. [Abstract] [PDF]  

PJ Rice, A Hamada, DD Miller, and PN Patil

Asymmetric catecholimidazolines and catecholamidines: affinity and efficacy relationships at the alpha adrenoreceptor in rat aorta
J Pharmacol Exp Ther 1987 242: 121-130. [Abstract] [PDF]  

CJ Helke, ET Phillips, and JT O'Neill

Intrathecal administration of a substance P receptor antagonist: studies on peripheral and central nervous system hemodynamics and on specificity of action
J Pharmacol Exp Ther 1987 242: 131-136. [Abstract] [PDF]  

ED Hall, JM McCall, RL Chase, PA Yonkers, and JM Braughler

A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage
J Pharmacol Exp Ther 1987 242: 137-142. [Abstract] [PDF]  

S Nagahama, HS Ann, YF Chen, MD Lindheimer, and S Oparil

Role of vasopressin in the cardiovascular effects of LY171555, a selective dopamine D2 receptor agonist: studies in conscious Brattleboro and Long-Evans rats
J Pharmacol Exp Ther 1987 242: 143-151. [Abstract] [PDF]  

PP Sokol, PD Holohan, and CR Ross

The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl- 1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles
J Pharmacol Exp Ther 1987 242: 152-157. [Abstract] [PDF]  

RJ Shebuski, EH Ohlstein, JM Jr Smith, and RR Jr Ruffolo

Enhanced pulmonary alpha-2 adrenoceptor responsiveness under conditions of elevated pulmonary vascular tone
J Pharmacol Exp Ther 1987 242: 158-165. [Abstract] [PDF]  

S Wanwimolruk and G Levy

Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition
J Pharmacol Exp Ther 1987 242: 166-172. [Abstract] [PDF]  

SH Zorn, RS Duman, A Giachetti, R Micheletti, E Giraldo, P Krogsgaard-Larsen, and SJ Enna

(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors
J Pharmacol Exp Ther 1987 242: 173-178. [Abstract] [PDF]  

JL Katz and SR Goldberg

Psychomotor stimulant effects of caffeine alone and in combination with an adenosine analog in the squirrel monkey
J Pharmacol Exp Ther 1987 242: 179-187. [Abstract] [PDF]  

RM Rapoport

Effects of norepinephrine on contraction and hydrolysis of phosphatidylinositols in rat aorta
J Pharmacol Exp Ther 1987 242: 188-194. [Abstract] [PDF]  

CP France and JH Woods

Morphine, saline and naltrexone discrimination in morphine-treated pigeons
J Pharmacol Exp Ther 1987 242: 195-202. [Abstract] [PDF]  

PM Beardsley and RL Balster

Behavioral dependence upon phencyclidine and ketamine in the rat
J Pharmacol Exp Ther 1987 242: 203-211. [Abstract] [PDF]  

JA Gray and RJ Kavlock

Pharmacologic probing of mercuric chloride-induced renal dysfunction in the neonatal rat
J Pharmacol Exp Ther 1987 242: 212-216. [Abstract] [PDF]  

N Aiyar, P Nambi, FL Stassen, and ST Crooke

Effects of N-ethylmaleimide on arginine vasopressin-induced responses in an established smooth muscle cell line
J Pharmacol Exp Ther 1987 242: 217-221. [Abstract] [PDF]  

BI Ghanayem, LT Burka, and HB Matthews

Metabolic basis of ethylene glycol monobutyl ether (2-butoxyethanol) toxicity: role of alcohol and aldehyde dehydrogenases
J Pharmacol Exp Ther 1987 242: 222-231. [Abstract] [PDF]  

TA Slotkin, L Orband-Miller, and KL Queen

Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions
J Pharmacol Exp Ther 1987 242: 232-237. [Abstract] [PDF]  

J Xu and DM Chuang

Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists
J Pharmacol Exp Ther 1987 242: 238-244. [Abstract] [PDF]  

DC Stump, L Kieckens, F De Cock, and D Collen

Pharmacokinetics of single chain forms of urokinase-type plasminogen activator
J Pharmacol Exp Ther 1987 242: 245-250. [Abstract] [PDF]  

E Hovav and M Weinstock

Temporal factors influencing the development of acute tolerance to opiates
J Pharmacol Exp Ther 1987 242: 251-256. [Abstract] [PDF]  

HN Doods, MJ Mathy, D Davidesko, KJ van Charldorp, A de Jonge, and PA van Zwieten

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors
J Pharmacol Exp Ther 1987 242: 257-262. [Abstract] [PDF]  

Z Terashita, Y Imura, M Takatani, S Tsushima, and K Nishikawa

CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo
J Pharmacol Exp Ther 1987 242: 263-268. [Abstract] [PDF]  

I Muramatsu, M Noda, M Nishio, and M Fujiwara

Mechanism of sodium channel block in crayfish giant axons by 711389-S, a new antiarrhythmic drug
J Pharmacol Exp Ther 1987 242: 269-276. [Abstract] [PDF]  

M Seiler and DG Weiss

Nocodazole irreversibly reduces the capacity of rapid axoplasmic transport in vitro
J Pharmacol Exp Ther 1987 242: 277-283. [Abstract] [PDF]  

GR Bolt, H Itoh, K Lederis, and KL MacCannell

Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by urotensin I, a selective mesenteric vasodilator peptide
J Pharmacol Exp Ther 1987 242: 284-291. [Abstract] [PDF]  

MP Moffat

Concentration-dependent effects of prostacyclin on the response of the isolated guinea pig heart to ischemia and reperfusion: possible involvement of the slow inward current
J Pharmacol Exp Ther 1987 242: 292-299. [Abstract] [PDF]  

S Consolo, CF Wu, and R Fusi

D-1 receptor-linked mechanism modulates cholinergic neurotransmission in rat striatum
J Pharmacol Exp Ther 1987 242: 300-305. [Abstract] [PDF]  

S Narumiya, K Ohno, M Fukushima, and M Fujiwara

Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei
J Pharmacol Exp Ther 1987 242: 306-311. [Abstract] [PDF]  

MD Threadgill, DB Axworthy, TA Baillie, PB Farmer, KC Farrow, A Gescher, P Kestell, PG Pearson, and AJ Shaw

Metabolism of N-methylformamide in mice: primary kinetic deuterium isotope effect and identification of S-(N-methylcarbamoyl)glutathione as a metabolite
J Pharmacol Exp Ther 1987 242: 312-319. [Abstract] [PDF]  

C Lambert, R Cardinal, M Vermeulen, D Lamontagne, R Nadeau, P Paradis, and JL Rouleau

Lack of relation between the ventricular refractory period prolongation by amiodarone and the thyroid state in rats
J Pharmacol Exp Ther 1987 242: 320-325. [Abstract] [PDF]  

S Yamada, N Ashizawa, H Ushijima, K Nakayama, E Hayashi, and K Honda

Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy
J Pharmacol Exp Ther 1987 242: 326-330. [Abstract] [PDF]  

BS Gan, MD Hollenberg, KL MacCannell, K Lederis, ME Winkler, and R Derynck

Distinct vascular actions of epidermal growth factor-urogastrone and transforming growth factor-alpha
J Pharmacol Exp Ther 1987 242: 331-337. [Abstract] [PDF]  

S Marleau, H Ong, L Gariepy, and P du Souich

Lidocaine and indocyanine green kinetics: effect of hypoxemia and/or hypercapnia
J Pharmacol Exp Ther 1987 242: 338-343. [Abstract] [PDF]  

DL Graham and P Skett

Endocrine regulation of the metabolism of 1-naphthol in the rat
J Pharmacol Exp Ther 1987 242: 344-348. [Abstract] [PDF]  

S Urien, JL Pinquier, B Paquette, P Chaumet-Riffaud, JR Kiechel, and JP Tillement

Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug
J Pharmacol Exp Ther 1987 242: 349-353. [Abstract] [PDF]  

P Haddad, PA Coulombe, and M Gascon-Barre

Influence of the vitamin D hormonal status on the hepatic response to bromobenzene
J Pharmacol Exp Ther 1987 242: 354-363. [Abstract] [PDF]  

RJ D'Amato, BL Largent, AM Snowman, and SH Snyder

Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine
J Pharmacol Exp Ther 1987 242: 364-371. [Abstract] [PDF]  

LF Chuang, RY Chuang, EM Acton, M Israel, and M Yu

Effect of morpholinyladriamycin analogs and adriamycin on the activities of DNA polymerase alpha and RNA polymerase II of chicken leukemia cells
J Pharmacol Exp Ther 1987 242: 372-377. [Abstract] [PDF]  

JA Mastrianni and AJ Ingenito

On the relationship between clonidine hypotension and brain beta- endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers
J Pharmacol Exp Ther 1987 242: 378-387. [Abstract] [PDF]  

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