Methoxyluteolin inhibits neuropeptide-stimulated TNF, CXCL8 and VEGF release via mTOR activation from human mast cells

Data Supplement

• Supplemental Figures -

  
  

  Supplementary Figure 1. Human MC degranulation in response to NT or SP is decreased by the PI3K inhibitor LY294002, luteolin and methoxyluteolin.  

  
  

  Supplementary Figure 2. Methoxyluteolin more potently than luteolin inhibits NT-stimulated pro-inflammatory mediator release from human MC.