Anti-Atherosclerotic Effects of A Novel Synthetic Tissue-Selective Steroidal LXR Agonist in LDLR-/- Mice

Data Supplement

Files in this Data Supplement:

• Data Supplement -
  Supplemental Fig. 1. Synthesis of 3α, 6α, 24-trihydroxy-24, 24-di(trifluoromethyl)-5β-cholane (ATI-829) (5).
  Supplemental Fig. 2. Information regarding compound T0901317, 22(R)-HC, 24(S)-HC and 24(S), 25-EC is available from the following references...
  Supplemental Fig. 3. Activation of nuclear receptors by their own agonists.
  Supplemental Fig. 4. effect of T0901317, ATI-829, 22(R)-HC, 24(S)-HC, and 24(S), 25-EC on luciferase reporter gene expression in HEK293 cells without expressing LXRα or LXRβ.