Dynamics of Aβ Turnover and Deposition in Different APP Transgenic Mouse Models Following Gamma-Secretase Inhibition

Data Supplement

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    Figure 1S. Dose dependency of Aβ reduction and CTF accumulation in pre-plaque APP23 mice after LY-411575 treatment...
    Figure 2S. Stronger reduction of Aβ in forebrain following subchronic as compared to acute g γ-secretase inhibition with LY-411575...
    Figure 3S. Decreased brain weight, increased CSF volume and change in coat color after chronic treatment of APP23 mice with LY-411575...
    Figure 4S. Aβ40 and A&beat;42 immunostaining in cortical pyramidal cells of APP23 mice after chronic γ secretase inhibition...

This Article

  1. Published online before print August 7, 2008, doi: 10.1124/jpet.108.140327
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