Abstract
1. Blindness has been produced in monkeys by the administration of the following compounds: atoxyl, tryparsamide, stovarsol, 3-amino-4-beta-hydroxy-ethoxy-phenylarsonic acid (No. 190), and 4-β-(β'-hydroxy)ethoxy-ethoxy-phenylarsonic acid (No. 266), the last containing no nitrogen in the molecule.
2. The work herein reported would appear to provide an experimental basis for detecting the blinding potentialities of arsenical compounds for man.
3. Means now become available for a study of prophylactic procedures designed to reduce or eliminate optic atrophy as a sequence of chemotherapy of neurosyphilis.
Footnotes
- Received July 17, 1942.
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