Research ArticleMetabolism, Transport, and Pharmacogenomics
Quantitative contribution of six major transporters to the hepatic uptake of drugs: 'SLC-phenotyping' using primary human hepatocytes
Yi-an Bi, Chester Costales, Sumathy Mathialagan, Mark West, Soraya Eatemadpour, Sarah Lazzaro, Laurie Tylaska, Renato Scialis, Hui Zhang, John Umland, Emi Kimoto, David A Tess, Bo Feng, Larry Tremaine, Manthena V. S. Varma and A. David Rodrigues
Journal of Pharmacology and Experimental Therapeutics April 11, 2019, jpet.119.257600; DOI: https://doi.org/10.1124/jpet.119.257600
Yi-an Bi
Pfizer, Inc.
Chester Costales
Pfizer, Inc.
Sumathy Mathialagan
Pfizer, Inc.
Mark West
Pfizer, Inc.
Soraya Eatemadpour
Pfizer, Inc.
Sarah Lazzaro
Pfizer, Inc.
Laurie Tylaska
Pfizer, Inc.
Renato Scialis
Pfizer, Inc.
Hui Zhang
Pfizer, Inc.
John Umland
Pfizer, Inc.
Emi Kimoto
Pfizer, Inc.
David A Tess
Pfizer, Inc.
Bo Feng
Pfizer, Inc.
Larry Tremaine
Pfizer, Inc.
Manthena V. S. Varma
Pfizer, Inc.
A. David Rodrigues
Pfizer, Inc.
Article Figures & Data
Additional Files
Data Supplement
- Supplemental Table -
Table S1: Observed DDIs of oral statins with a single dose oral 600mg rifampicin.
- Supplemental Table -
In this issue
Research ArticleMetabolism, Transport, and Pharmacogenomics
Quantitative contribution of six major transporters to the hepatic uptake of drugs: 'SLC-phenotyping' using primary human hepatocytes
Yi-an Bi, Chester Costales, Sumathy Mathialagan, Mark West, Soraya Eatemadpour, Sarah Lazzaro, Laurie Tylaska, Renato Scialis, Hui Zhang, John Umland, Emi Kimoto, David A Tess, Bo Feng, Larry Tremaine, Manthena V. S. Varma and A. David Rodrigues
Journal of Pharmacology and Experimental Therapeutics April 11, 2019, jpet.119.257600; DOI: https://doi.org/10.1124/jpet.119.257600
Research ArticleMetabolism, Transport, and Pharmacogenomics
Quantitative contribution of six major transporters to the hepatic uptake of drugs: 'SLC-phenotyping' using primary human hepatocytes
Yi-an Bi, Chester Costales, Sumathy Mathialagan, Mark West, Soraya Eatemadpour, Sarah Lazzaro, Laurie Tylaska, Renato Scialis, Hui Zhang, John Umland, Emi Kimoto, David A Tess, Bo Feng, Larry Tremaine, Manthena V. S. Varma and A. David Rodrigues
Journal of Pharmacology and Experimental Therapeutics April 11, 2019, jpet.119.257600; DOI: https://doi.org/10.1124/jpet.119.257600
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