Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Disrupted Murine Gut to Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evan, Albert P Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
Journal of Pharmacology and Experimental Therapeutics October 27, 2016, jpet.116.236935; DOI: https://doi.org/10.1124/jpet.116.236935
Edwin C. Y. Chow
1 1Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canad;
Holly P. Quach
2 Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada;
Yueping Zhang
3 Bristol Myers Squibb, Pharmaceutical Candidate Optimization Dept, Princeton, NJ 08540, USA;
Jason Z. Y. Wang
2 Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada;
David C. Evan
4 Pharmacokinetics Dynamics of & Metabolism, Janssen Research and Development, LLC, Spring House, PA;
Albert P Li
5 In Vitro ADMET Laboratories, 9221 Rumsey Rd, Suite 8, Columbia, MD 21045, USA;
Jose Silva
4 Pharmacokinetics Dynamics of & Metabolism, Janssen Research and Development, LLC, Spring House, PA;
Rommel G. Tirona
6 Department of Physiology and Pharmacology and Medicine, University of Western Ontario, London, ON
Yurong Lai
3 Bristol Myers Squibb, Pharmaceutical Candidate Optimization Dept, Princeton, NJ 08540, USA;
K. Sandy Pang
2 Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada;
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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Disrupted Murine Gut to Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evan, Albert P Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
Journal of Pharmacology and Experimental Therapeutics October 27, 2016, jpet.116.236935; DOI: https://doi.org/10.1124/jpet.116.236935
Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Disrupted Murine Gut to Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evan, Albert P Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
Journal of Pharmacology and Experimental Therapeutics October 27, 2016, jpet.116.236935; DOI: https://doi.org/10.1124/jpet.116.236935
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