Research ArticleNeuropharmacology
VU0477573: Partial negative allosteric modulator of the subtype 5 metabotropic glutamate receptor with in vivo efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, Ryan D Morrison, Brittney S Bates, Shaun R Stauffer, Kyle A Emmitte, Michael Bubser, Weimin Peng, Michael T Nedelcovych, Analisa Thompson, Xiaohui Lv, Zixiu Xiang, J Scott Daniels, Colleen M Niswender, Craig W Lindsley, Carrie K Jones and P Jeffrey Conn
Journal of Pharmacology and Experimental Therapeutics October 26, 2015, jpet.115.226597; DOI: https://doi.org/10.1124/jpet.115.226597
Hilary Highfield Nickols
1 Vanderbilt;
Joannes P Yuh
1 Vanderbilt;
Karen J Gregory
2 Monash University
Ryan D Morrison
1 Vanderbilt;
Brittney S Bates
1 Vanderbilt;
Shaun R Stauffer
1 Vanderbilt;
Kyle A Emmitte
1 Vanderbilt;
Michael Bubser
1 Vanderbilt;
Weimin Peng
1 Vanderbilt;
Michael T Nedelcovych
1 Vanderbilt;
Analisa Thompson
1 Vanderbilt;
Xiaohui Lv
1 Vanderbilt;
Zixiu Xiang
1 Vanderbilt;
J Scott Daniels
1 Vanderbilt;
Colleen M Niswender
1 Vanderbilt;
Craig W Lindsley
1 Vanderbilt;
Carrie K Jones
1 Vanderbilt;
P Jeffrey Conn
1 Vanderbilt;
Article Figures & Data
Additional Files
Data Supplement
Files in this Data Supplement:
- Supplemental Figures - Figure S1. Simulating negative allosteric modulators of mGlu5 with weak negative cooperativity. Figure S2: Calculating 3H-mPEPy occupancy.
In this issue
Research ArticleNeuropharmacology
VU0477573: Partial negative allosteric modulator of the subtype 5 metabotropic glutamate receptor with in vivo efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, Ryan D Morrison, Brittney S Bates, Shaun R Stauffer, Kyle A Emmitte, Michael Bubser, Weimin Peng, Michael T Nedelcovych, Analisa Thompson, Xiaohui Lv, Zixiu Xiang, J Scott Daniels, Colleen M Niswender, Craig W Lindsley, Carrie K Jones and P Jeffrey Conn
Journal of Pharmacology and Experimental Therapeutics October 26, 2015, jpet.115.226597; DOI: https://doi.org/10.1124/jpet.115.226597
Research ArticleNeuropharmacology
VU0477573: Partial negative allosteric modulator of the subtype 5 metabotropic glutamate receptor with in vivo efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, Ryan D Morrison, Brittney S Bates, Shaun R Stauffer, Kyle A Emmitte, Michael Bubser, Weimin Peng, Michael T Nedelcovych, Analisa Thompson, Xiaohui Lv, Zixiu Xiang, J Scott Daniels, Colleen M Niswender, Craig W Lindsley, Carrie K Jones and P Jeffrey Conn
Journal of Pharmacology and Experimental Therapeutics October 26, 2015, jpet.115.226597; DOI: https://doi.org/10.1124/jpet.115.226597
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