Research ArticleNeuropharmacology
Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574
Christopher L. Shaffer, Raymond S Hurst, Renato J Scialis, Sarah M Osgood, Dianne K Bryce, William E Hoffmann, John T Lazzaro, Ashley N Hanks, Susan Lotarski, Mark L Weber, JianHua Liu, Frank S Menniti, Christopher J Schmidt and Mihaly Hajos
Journal of Pharmacology and Experimental Therapeutics July 30, 2013, jpet.113.204735; DOI: https://doi.org/10.1124/jpet.113.204735
Christopher L. Shaffer
1 Pfizer Global Research & Development;
Raymond S Hurst
2 Amgen Inc.;
Renato J Scialis
1 Pfizer Global Research & Development;
Sarah M Osgood
1 Pfizer Global Research & Development;
Dianne K Bryce
3 Bristol-Myers Squibb Company;
William E Hoffmann
1 Pfizer Global Research & Development;
John T Lazzaro
1 Pfizer Global Research & Development;
Ashley N Hanks
1 Pfizer Global Research & Development;
Susan Lotarski
1 Pfizer Global Research & Development;
Mark L Weber
1 Pfizer Global Research & Development;
JianHua Liu
1 Pfizer Global Research & Development;
Frank S Menniti
4 Mnemosyne Pharmaceuticals, Inc.;
Christopher J Schmidt
1 Pfizer Global Research & Development;
Mihaly Hajos
5 Yale School of Medicine
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Research ArticleNeuropharmacology
Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574
Christopher L. Shaffer, Raymond S Hurst, Renato J Scialis, Sarah M Osgood, Dianne K Bryce, William E Hoffmann, John T Lazzaro, Ashley N Hanks, Susan Lotarski, Mark L Weber, JianHua Liu, Frank S Menniti, Christopher J Schmidt and Mihaly Hajos
Journal of Pharmacology and Experimental Therapeutics July 30, 2013, jpet.113.204735; DOI: https://doi.org/10.1124/jpet.113.204735
Research ArticleNeuropharmacology
Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574
Christopher L. Shaffer, Raymond S Hurst, Renato J Scialis, Sarah M Osgood, Dianne K Bryce, William E Hoffmann, John T Lazzaro, Ashley N Hanks, Susan Lotarski, Mark L Weber, JianHua Liu, Frank S Menniti, Christopher J Schmidt and Mihaly Hajos
Journal of Pharmacology and Experimental Therapeutics July 30, 2013, jpet.113.204735; DOI: https://doi.org/10.1124/jpet.113.204735
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