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More articles from Metabolism, Transport, and Pharmacogenomics

  • Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
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    Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
    Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
    Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382
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    Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice
    Joseph A. Cichocki, Shinji Furuya, Kranti Konganti, Yu-Syuan Luo, Thomas J. McDonald, Yasuhiro Iwata, Weihsueh A. Chiu, David W. Threadgill, Igor P. Pogribny and Ivan Rusyn
    Journal of Pharmacology and Experimental Therapeutics April 2017, 361 (1) 17-28; DOI: https://doi.org/10.1124/jpet.116.238790
  • Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations
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    Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations
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    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 484-495; DOI: https://doi.org/10.1124/jpet.116.237438
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    Hormonal and Chemical Regulation of the Glut9 Transporter in Mice
    Pengli Bu, Yuan Le, Yue Zhang and Xingguo Cheng
    Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 206-214; DOI: https://doi.org/10.1124/jpet.116.237040
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    Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
    Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
    Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214
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    Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
    Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
    Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594
  • Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
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    Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
    N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
    Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495
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    Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
    Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
    Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984
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    Blood–Brain Barrier Disruption and Neurovascular Unit Dysfunction in Diabetic Mice: Protection with the Mitochondrial Carbonic Anhydrase Inhibitor Topiramate
    Therese S. Salameh, Gul N. Shah, Tulin O. Price, Melvin R. Hayden and William A. Banks
    Journal of Pharmacology and Experimental Therapeutics December 2016, 359 (3) 452-459; DOI: https://doi.org/10.1124/jpet.116.237057
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    Impact of Substrate-Dependent Inhibition on Renal Organic Cation Transporters hOCT2 and hMATE1/2-K-Mediated Drug Transport and Intracellular Accumulation
    Jia Yin, Haichuan Duan and Joanne Wang
    Journal of Pharmacology and Experimental Therapeutics December 2016, 359 (3) 401-410; DOI: https://doi.org/10.1124/jpet.116.236158

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