Abstract
Intravenous sodium succinate was more effective in counteracting pentobarbital anesthesia than intraperitoneal injection of the same quantity of succinate.
Intravenous sucrose in large quantities was followed by a decrease in sleeping time comparable to that with intravenous succinate.
Intravenous succinate or sucrose resulted in immediate diuresis. Intraperitoneal succinate was followed by a delayed excretion of urine similar to the antidiuretic effects of the control animals.
The length of pentobarbital anesthesia appears to be correlated in general with the degree of diuresis produced by the various drugs used and the method of injection.
Footnotes
- Received August 26, 1946.
- 1946 by The American Society for Pharmacology and Experimental Therapeutics
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