II. INFLUENCE OF DIETARY FACTORS ON THE TOXICITY OF DICHLOROPROPANE
Abstract
(1) Weaning rats prepared for several weeks on low protein-choline deficient diets were more susceptible to the effects of inhalation exposures to 1,2-dichloropropane than were control rats on an adequate diet. This was true even in pairfeeding experiments.
(2) Supplements of choline did not appreciably increase the resistance of the choline deficient-protein deficient rats. dl-Methionine and the combination of l-cystine plus choline were quite effective.
(3) The pathological lesions found in exposed and control rats are described.
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