Abstract
Parenteral administration of berberine has been shown to give rise to a statistically significant prolongation of the lives of rats infected with Trypanosoma equiperdum.
Berberine has been shown to potentiate procaine anesthesia in the frog and the dog but not in the rabbit and man. In man berberine is an anesthetic in itself, but occasional toxic aftereffects would preclude its clinical use.
Footnotes
- Received February 26, 1940.
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