Abstract
1. Dogs, rabbits, chickens, white rats, and guinea pigs were exposed to known concentrations of gaseous hydrocyanic acid for long periods.
2. The critical level for various animals has been measured and is shown by the onset of convulsions.
3. Below the critical level hydrocyanic acid is efficiently dealt with by the detoxifying mechanism for an unlimited time.
4. There is no evidence of tolerance or increased susceptibility.
5. Methylene blue has but little value as a treatment for cyanide poisoning above the critical level.
6. Methylene blue has considerable value as a prophylactic against concentrations of hydrocyanic acid above the critical level.
Footnotes
- Received August 3, 1936.
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