Abstract
Ketonuria in fasting female rats anesthetized with ether is much greater than that of male rats treated similarly, particularly on the third and fourth days of fasting when the resultant ether ketosis is at its height. Subcutaneous injection of epinephrine hydrochloride in divided doses of 0.2 mgm. per kilogram at four-hour intervals did not result in a ketosis in either male or female animals. Thus, if ether ketosis is mediated through stimulation of epinephrine output, this effect must be greater than that obtained by subcutaneous injection of the above doses of epinephrine hydrochloride. Apparently the same mechanisms function in ether ketosis as are present in less obscure ketoses.
Footnotes
- Received June 17, 1935.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.