Abstract
1. The sodium salts of o-m- and p-cresotinic acids have a powerful specific action in acute rheumatic conditions.
2. They are for practical purposes inferior to sodium salicylate: (1) The ortho-cresotinate, even in comparatively moderate doses, slows and depresses the heart; (2) the para-cresotinate is not nearly so efficacious; (3) the meta-cresotinate, while very similar in strength, has no advantages over the salicylate.
3. So far as I tested them, they have no therapeutical actions which are not possessed by sodium salicylate.
Footnotes
- Received October 9, 1912.
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