Index by author
July 01, 2020; Volume 374,Issue 1
A
Ahmed, Faizy
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Ajith, Siddarth
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Allison, Dan
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Altenburger, Jean-Michel
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
An, Guohua
- You have accessSimultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide HydrolaseNan Wu, Bruce D. Hammock, Kin Sing Stephen Lee and Guohua AnJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 223-232; DOI: https://doi.org/10.1124/jpet.120.265330
Anderson, Katie
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Andreassen, Kim Vietz
- You have accessThe Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist TherapyAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, Morten Asser Karsdal and Kim HenriksenJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 74-83; DOI: https://doi.org/10.1124/jpet.119.263392
Ashton, J.C.
- You have accessInhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung CancerN. Shrestha, A.R. Bland, R.L. Bower, R.J. Rosengren and J.C. AshtonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 134-140; DOI: https://doi.org/10.1124/jpet.120.266049
B
Baker, Brian
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Barbe, Fabrice
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Barnstein, Brian O.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Beauverger, Philippe
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Becanovic, Kristina
- You have accessEffects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and NeurotransmissionKristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per SvenningssonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
Belleville, Karine
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Beltran, Nina M.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Bidouard, Jean-Pierre
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Billgren, Jens
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Bland, A.R.
- You have accessInhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung CancerN. Shrestha, A.R. Bland, R.L. Bower, R.J. Rosengren and J.C. AshtonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 134-140; DOI: https://doi.org/10.1124/jpet.120.266049
Blough, Bruce E.
- You have accessEvaluation of the Reinforcing Strength of Phendimetrazine Using a Progressive-Ratio Schedule of Reinforcement in Rhesus MonkeysMolly Minkiewicz, Paul W. Czoty, Bruce E. Blough and Michael A. NaderJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 1-5; DOI: https://doi.org/10.1124/jpet.120.264952
Boekema, P.H.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Bolden, Chris T.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Bower, R.L.
- You have accessInhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung CancerN. Shrestha, A.R. Bland, R.L. Bower, R.J. Rosengren and J.C. AshtonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 134-140; DOI: https://doi.org/10.1124/jpet.120.266049
Briand, Véronique
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Burn, Timothy
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
C
Calcutt, Nigel A.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Carta, Manolo
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Caslin, Heather L.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Cheng, Hsuan-Ping
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
Choi, Man Ho
- You have access7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human HepatocytesJin Huang, Seung-Jin Lee, Saeromi Kang, Man Ho Choi and Dong-Soon ImJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 142-150; DOI: https://doi.org/10.1124/jpet.120.264960
Collier, Paul
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Collins, Robert
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Combs, Andrew
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Covington, Maryanne
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Cruz, Bryan
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Czoty, Paul W.
- You have accessEvaluation of the Reinforcing Strength of Phendimetrazine Using a Progressive-Ratio Schedule of Reinforcement in Rhesus MonkeysMolly Minkiewicz, Paul W. Czoty, Bruce E. Blough and Michael A. NaderJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 1-5; DOI: https://doi.org/10.1124/jpet.120.264952
D
Dailey, Jordan M.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Das, Aditi
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Demeule, Michel
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Diamond, Sharon
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Dömling, A.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Douty, Brent
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Dutzar, Benjamin
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
E
Edling, Malin
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Eiselt, Émilie
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Elsinga, P.H.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Erceg, S.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Ewing, Laura E.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
F
Fagerberg, Anne
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Fantegrossi, William E.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Feldman, Patricia
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Fernyhough, Paul
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Flores-Robles, Grace
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Frizzi, Katie E.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Fukuoka, Yoshihiro
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
G
Gao, Mingming
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Garcia-Martinez, Leon F.
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Gendron, Louis
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Gewirtz, David A.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Ghidini, Andrea
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Gonzalez, Adrian T.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Gosens, R.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Grant, Alice H.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Guernsey, Lucie S.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Guillon, Jean-Michel
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Gunnergren, Jenny
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Guo, Leiming
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
H
Hall, Leslie
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Hambuchen, Michael D.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Hammock, Bruce D.
- You have accessSimultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide HydrolaseNan Wu, Bruce D. Hammock, Kin Sing Stephen Lee and Guohua AnJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 223-232; DOI: https://doi.org/10.1124/jpet.120.265330
Han, May Madi
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Hansbury, Michael
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Haque, Tamara T.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Hardin, Ethan J.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Harris, Eric W.
- You have accessAnalgesia with Gabapentin and Pregabalin May Involve N-Methyl-d-Aspartate Receptors, Neurexins, and ThrombospondinsCharles P. Taylor and Eric W. HarrisJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 161-174; DOI: https://doi.org/10.1124/jpet.120.266056
Hay, Charles E.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
He, Xin
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Henriksen, Kim
- You have accessThe Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist TherapyAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, Morten Asser Karsdal and Kim HenriksenJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 74-83; DOI: https://doi.org/10.1124/jpet.119.263392
Hjorth, Stephan
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Hollis, Greg
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Huang, Jin
- You have access7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human HepatocytesJin Huang, Seung-Jin Lee, Saeromi Kang, Man Ho Choi and Dong-Soon ImJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 142-150; DOI: https://doi.org/10.1124/jpet.120.264960
Huber, Reid
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Huestis, Marilyn A.
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Huff, Hannah
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Hulsbeek, I.R.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
I
Ikeda, Takanori
- You have accessEzetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux TransportersYuji Tanaka, Takanori Ikeda, Hiroshi Ogawa and Toshinori KamisakoJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 175-183; DOI: https://doi.org/10.1124/jpet.120.265660
Im, Dong-Soon
- You have access7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human HepatocytesJin Huang, Seung-Jin Lee, Saeromi Kang, Man Ho Choi and Dong-Soon ImJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 142-150; DOI: https://doi.org/10.1124/jpet.120.264960
J
Janiak, Philip
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Jolivalt, Corinne G.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
K
Kamisako, Toshinori
- You have accessEzetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux TransportersYuji Tanaka, Takanori Ikeda, Hiroshi Ogawa and Toshinori KamisakoJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 175-183; DOI: https://doi.org/10.1124/jpet.120.265660
Kang, Saeromi
- You have access7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human HepatocytesJin Huang, Seung-Jin Lee, Saeromi Kang, Man Ho Choi and Dong-Soon ImJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 142-150; DOI: https://doi.org/10.1124/jpet.120.264960
Karasek, Charlie
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Karsdal, Morten Asser
- You have accessThe Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist TherapyAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, Morten Asser Karsdal and Kim HenriksenJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 74-83; DOI: https://doi.org/10.1124/jpet.119.263392
Katiyar, Kamna
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Kee, Sydney A.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Kema, I.P.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Kistemaker, L.E.M.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Kiwanuka, Kasalina N.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Koblish, Holly
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Kolawole, Motunrayo
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Kotra, Lakshmi P.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
Kovacevich, Brian
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Kullingsjö, Johan
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Kurhade, S.H.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
L
Larocque, Alain
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Larsen, Anna Thorsø
- You have accessThe Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist TherapyAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, Morten Asser Karsdal and Kim HenriksenJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 74-83; DOI: https://doi.org/10.1124/jpet.119.263392
Latham, John A.
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Le, Quang T.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Lee, Kin Sing Stephen
- You have accessSimultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for Their Pharmacological Target: Soluble Epoxide HydrolaseNan Wu, Bruce D. Hammock, Kin Sing Stephen Lee and Guohua AnJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 223-232; DOI: https://doi.org/10.1124/jpet.120.265330
Lee, Seung-Jin
- You have access7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human HepatocytesJin Huang, Seung-Jin Lee, Saeromi Kang, Man Ho Choi and Dong-Soon ImJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 142-150; DOI: https://doi.org/10.1124/jpet.120.264960
Leffet, Lynn
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Li, Yanlong
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Li, Yun-Long
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Liu, Phillip C.C.
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Ljung, Elisabeth
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Lu, Jin
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
M
Ma, Xiaochao
- You have accessABCG2 Deficiency Does Not Alter Dolutegravir Metabolism and PharmacokineticsJunjie Zhu, Xin Tian, Amina I. Shehu, Deborah K. McMahon and Xiaochao MaJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 38-43; DOI: https://doi.org/10.1124/jpet.119.264424
Maarsingh, H.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Mahler, Stephen V.
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Marek, Gerard J.
- You have accessExtending the Specificity of DRL 72-s Behavior for Screening Antidepressant-Like Effects of Glutamatergic Clinically Validated Anxiolytic or Antidepressant Drugs in RatsGerard J. Marek and Allyson A. SalekJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 200-210; DOI: https://doi.org/10.1124/jpet.119.264069
Margaritis, Paris
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Martin, Rebecca K.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Martinez, Arantxa K.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
McLeod, Jamie Josephine Avila
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
McMahon, Deborah K.
- You have accessABCG2 Deficiency Does Not Alter Dolutegravir Metabolism and PharmacokineticsJunjie Zhu, Xin Tian, Amina I. Shehu, Deborah K. McMahon and Xiaochao MaJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 38-43; DOI: https://doi.org/10.1124/jpet.119.264424
McNeil, Brandon
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Metcalf, Brian
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Meurs, H.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Minkiewicz, Molly
- You have accessEvaluation of the Reinforcing Strength of Phendimetrazine Using a Progressive-Ratio Schedule of Reinforcement in Rhesus MonkeysMolly Minkiewicz, Paul W. Czoty, Bruce E. Blough and Michael A. NaderJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 1-5; DOI: https://doi.org/10.1124/jpet.120.264952
Mizutani, Hiroya
- You have accessTAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive BladderHiroya Mizutani, Fukumitsu Sakakibara and Eiji SasakiJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 84-92; DOI: https://doi.org/10.1124/jpet.119.264572
Mota, Andre J.
- You have accessTopical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic MiceCorinne G. Jolivalt, Katie E. Frizzi, May Madi Han, Andre J. Mota, Lucie S. Guernsey, Lakshmi P. Kotra, Paul Fernyhough and Nigel A. CalcuttJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 44-51; DOI: https://doi.org/10.1124/jpet.120.265447
N
Nader, Michael A.
- You have accessEvaluation of the Reinforcing Strength of Phendimetrazine Using a Progressive-Ratio Schedule of Reinforcement in Rhesus MonkeysMolly Minkiewicz, Paul W. Czoty, Bruce E. Blough and Michael A. NaderJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 1-5; DOI: https://doi.org/10.1124/jpet.120.264952
Newton, Robert
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
O
O’Connor, Sybil
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Ogawa, Hiroshi
- You have accessEzetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux TransportersYuji Tanaka, Takanori Ikeda, Hiroshi Ogawa and Toshinori KamisakoJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 175-183; DOI: https://doi.org/10.1124/jpet.120.265660
Ojala, Ethan W.
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Otis, Valérie
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Owens, S. Michael
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Ozoux, Marie-Laure
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
P
Paez, Patrick A.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Pelat, Michel
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Peterson, Eric C.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Petit, Frédéric
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Piomelli, Daniele
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
Poirier, Bruno
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
R
Ramos, Jeremiah
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Raport, Carol J.
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Régina, Anthony
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Roberts, Alan
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Rosengren, R.J.
- You have accessInhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung CancerN. Shrestha, A.R. Bland, R.L. Bower, R.J. Rosengren and J.C. AshtonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 134-140; DOI: https://doi.org/10.1124/jpet.120.266049
Ryan, John J.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
S
Sakakibara, Fukumitsu
- You have accessTAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive BladderHiroya Mizutani, Fukumitsu Sakakibara and Eiji SasakiJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 84-92; DOI: https://doi.org/10.1124/jpet.119.264572
Salek, Allyson A.
- You have accessExtending the Specificity of DRL 72-s Behavior for Screening Antidepressant-Like Effects of Glutamatergic Clinically Validated Anxiolytic or Antidepressant Drugs in RatsGerard J. Marek and Allyson A. SalekJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 200-210; DOI: https://doi.org/10.1124/jpet.119.264069
Sarret, Philippe
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Sasaki, Eiji
- You have accessTAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive BladderHiroya Mizutani, Fukumitsu Sakakibara and Eiji SasakiJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 84-92; DOI: https://doi.org/10.1124/jpet.119.264572
Scalley-Kim, Michelle
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Schaeffer, Paul
- Open AccessPotential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated ComorbiditiesMarie-Laure Ozoux, Véronique Briand, Michel Pelat, Fabrice Barbe, Paul Schaeffer, Philippe Beauverger, Bruno Poirier, Jean-Michel Guillon, Frédéric Petit, Jean-Michel Altenburger, Jean-Pierre Bidouard and Philip JaniakJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 24-37; DOI: https://doi.org/10.1124/jpet.120.265496
Scherle, Peggy
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Schwartz, Lawrence B.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Seigel, Gail M.
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
Serafine, Katherine M.
- You have accessThe Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D1 Receptor Agonist SKF 82958Jeremiah Ramos, Ethan J. Hardin, Alice H. Grant, Grace Flores-Robles, Adrian T. Gonzalez, Bryan Cruz, Arantxa K. Martinez, Nina M. Beltran and Katherine M. SerafineJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 6-15; DOI: https://doi.org/10.1124/jpet.119.263293
Shah, Dhaval K.
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
Shehu, Amina I.
- You have accessABCG2 Deficiency Does Not Alter Dolutegravir Metabolism and PharmacokineticsJunjie Zhu, Xin Tian, Amina I. Shehu, Deborah K. McMahon and Xiaochao MaJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 38-43; DOI: https://doi.org/10.1124/jpet.119.264424
Shin, Niu
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Shrestha, N.
- You have accessInhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung CancerN. Shrestha, A.R. Bland, R.L. Bower, R.J. Rosengren and J.C. AshtonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 134-140; DOI: https://doi.org/10.1124/jpet.120.266049
Shuey, Dana
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Singh, Aman P.
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
Small, Juliana C.
- You have accessThe Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine AbuseCharles E. Hay, Laura E. Ewing, Michael D. Hambuchen, Shannon M. Zintner, Juliana C. Small, Chris T. Bolden, William E. Fantegrossi, Paris Margaritis, S. Michael Owens and Eric C. PetersonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 16-23; DOI: https://doi.org/10.1124/jpet.119.261180
Soloviev, Maxim
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Sonesson, Clas
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Sonne, Nina
- You have accessThe Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist TherapyAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, Morten Asser Karsdal and Kim HenriksenJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 74-83; DOI: https://doi.org/10.1124/jpet.119.263392
Sousa, Vasco C.
- You have accessEffects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and NeurotransmissionKristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per SvenningssonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
Stewart, Erica
- Open AccessPharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideLeon F. Garcia-Martinez, Carol J. Raport, Ethan W. Ojala, Benjamin Dutzar, Katie Anderson, Erica Stewart, Brian Kovacevich, Brian Baker, Jens Billgren, Michelle Scalley-Kim, Charlie Karasek, Dan Allison and John A. LathamJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 93-103; DOI: https://doi.org/10.1124/jpet.119.264671
Straus, David B.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Stubbs, Matthew
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Svanberg, Boel
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Svenningsson, Per
- You have accessEffects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and NeurotransmissionKristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per SvenningssonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
Svensson, Peder
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
T
Tanaka, Yuji
- You have accessEzetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux TransportersYuji Tanaka, Takanori Ikeda, Hiroshi Ogawa and Toshinori KamisakoJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 175-183; DOI: https://doi.org/10.1124/jpet.120.265660
Taruselli, Marcela T.
- You have accessFluvastatin Induces Apoptosis in Primary and Transformed Mast CellsPatrick A. Paez, Motunrayo Kolawole, Marcela T. Taruselli, Siddarth Ajith, Jordan M. Dailey, Sydney A. Kee, Tamara T. Haque, Brian O. Barnstein, Jamie Josephine Avila McLeod, Heather L. Caslin, Kasalina N. Kiwanuka, Yoshihiro Fukuoka, Quang T. Le, Lawrence B. Schwartz, David B. Straus, David A. Gewirtz, Rebecca K. Martin and John J. RyanJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 104-112; DOI: https://doi.org/10.1124/jpet.119.264234
Taylor, Charles P.
- You have accessAnalgesia with Gabapentin and Pregabalin May Involve N-Methyl-d-Aspartate Receptors, Neurexins, and ThrombospondinsCharles P. Taylor and Eric W. HarrisJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 161-174; DOI: https://doi.org/10.1124/jpet.120.266056
Tedroff, Joakim
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
- You have accessEffects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and NeurotransmissionKristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per SvenningssonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
Tian, Xin
- You have accessABCG2 Deficiency Does Not Alter Dolutegravir Metabolism and PharmacokineticsJunjie Zhu, Xin Tian, Amina I. Shehu, Deborah K. McMahon and Xiaochao MaJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 38-43; DOI: https://doi.org/10.1124/jpet.119.264424
Torrens, Alexa
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
V
van den Berg, M.P.M.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
van Faassen, M.
- You have accessPharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors with Efficacy against Allergen-Induced Airway Narrowing In Vitro and In VivoM.P.M. van den Berg, S.H. Kurhade, H. Maarsingh, S. Erceg, I.R. Hulsbeek, P.H. Boekema, L.E.M. Kistemaker, M. van Faassen, I.P. Kema, P.H. Elsinga, A. Dömling, H. Meurs and R. GosensJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 62-73; DOI: https://doi.org/10.1124/jpet.119.264341
Verma, Ashwni
- You have accessEvolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander EffectAman P. Singh, Gail M. Seigel, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Hsuan-Ping Cheng and Dhaval K. ShahJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 184-199; DOI: https://doi.org/10.1124/jpet.119.262287
Vittoria de Donno, Maria
- You have accessEffects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and NeurotransmissionKristina Becanovic, Maria Vittoria de Donno, Vasco C. Sousa, Joakim Tedroff and Per SvenningssonJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 126-133; DOI: https://doi.org/10.1124/jpet.119.264754
Vozella, Valentina
- You have accessComparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male MiceAlexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V. Mahler, Marilyn A. Huestis, Aditi Das and Daniele PiomelliJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 151-160; DOI: https://doi.org/10.1124/jpet.120.265892
W
Waeltz, Paul
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Wang, Kathy He
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Wang, Qian
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Waters, Nicholas
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Waters, Susanna
- Open AccessPreclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson DiseaseSusanna Waters, Clas Sonesson, Peder Svensson, Joakim Tedroff, Manolo Carta, Elisabeth Ljung, Jenny Gunnergren, Malin Edling, Boel Svanberg, Anne Fagerberg, Johan Kullingsjö, Stephan Hjorth and Nicholas WatersJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 113-125; DOI: https://doi.org/10.1124/jpet.119.264226
Wong, Gloria Gao-Li
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Wu, Nan
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Yang, Gaoqiang
- Open AccessUse of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the BrainÉmilie Eiselt, Valérie Otis, Karine Belleville, Gaoqiang Yang, Alain Larocque, Anthony Régina, Michel Demeule, Philippe Sarret and Louis GendronJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 52-61; DOI: https://doi.org/10.1124/jpet.119.263566
Yang, Gengjie
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Yao, Wenqing
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Yeleswaram, Swamy
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
Yue, Eddy W.
- Open AccessParsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell MalignancyNiu Shin, Matthew Stubbs, Holly Koblish, Eddy W. Yue, Maxim Soloviev, Brent Douty, Kathy He Wang, Qian Wang, Mingming Gao, Patricia Feldman, Gengjie Yang, Leslie Hall, Michael Hansbury, Sybil O’Connor, Lynn Leffet, Robert Collins, Kamna Katiyar, Xin He, Paul Waeltz, Paul Collier, Jin Lu, Yun-Long Li, Yanlong Li, Phillip C.C. Liu, Timothy Burn, Maryanne Covington, Sharon Diamond, Dana Shuey, Alan Roberts, Swamy Yeleswaram, Greg Hollis, Brian Metcalf, Wenqing Yao, Reid Huber, Andrew Combs, Robert Newton and Peggy ScherleJournal of Pharmacology and Experimental Therapeutics July 2020, 374 (1) 211-222; DOI: https://doi.org/10.1124/jpet.120.265538
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Zhu, Junjie
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Zintner, Shannon M.
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