Insulin | l-valine and phenylboronic acid modified chitosan-based multifunctional nanocarrier | To overcome multiple barriers for oral insulin delivery | Li et al. (2017) |
Insulin | PLGA and Pluronic F68 based nanoparticles | To enhance the bioavailability using negatively changed nanoparticles for better absorption | Czuba et al. (2018) |
Curcumin | Folic acid conjugated PLGA–PEG copolymer based nanosystem | To carryout site specific release of hydrophobic anti-cancer drugs | Pillai et al. (2015) |
Curcumin | N-carboxymethyl chitosan based nanoparticles | To enhance the drug delivery to lymphatic system | Baek and Cho (2017) |
Curcumin | Polyacrylamide-grafted-xanthan gum based nanoparticles | To improve the bioavailability of drug for colon targeting | Mutalik et al. (2016) |
Paclitaxel and curcumin | Folate conjugated lipid nanoparticles | To co-deliver both drugs to enhance uptake and inhibit multidrug resistant | Liu et al. (2017) |
Cisplatin prodrug [Asplatin, c,c,t-[PtCl2(NH3)2(OH) (aspirin)] | Cholesterol–asplatin-incorporated mPEG-PLGA nanoparticles | To improve the oral delivery with improved efficacy and reduced toxicity | Cheng et al. (2015) |
Doxorubicin | HN-1 medicated PEGylated DOX | To improve the penetration efficiency to oral squamous cell carcinoma | Wang et al. (2017b) |
Triclabendazole | Chitosan 70/5 and Miglyol 812 | To develop oral nanoformulation for anti-parasitic drugs | Real et al. (2018) |
Cyclosporine A | Lipid nanoparticles | To enhance drug delivery | Guada et al. (2016) |
Betulinic acid | PLGA based nanoparticles | For improved anti- hepatocellular carcinoma activity than the parent compound | Kumar et al. (2018) |
Olmesartan medoxomil | Lipid nanoparticles | To enhance oral bioavailability | Kaithwas et al. (2017) |
Epirubicin | PLGA based nanoparticles with PEG modification | To improve permeability across the ileum of Rodent | Tariq et al. (2016) |
Scutellarin | Nanosystem based on chitosan derivatives | To enhance oral bioavailability | Wang et al. (2017) |
Resveratrol | Zein-based nanoparticles | Improved oral bioavailability and anti-inflammatory effects | Penalva et al. (2015) |
Superoxide dismutase | Zein-alginate nanoparticles | For steady state release of drug to decrease endotoxicity of IP administration | Lee et al. (2016) |
Quercetin | Modified chitosan and alginate nanoparticles | To reduce blood glucose levels in diabetic rats | Mukhopadhyay et al. (2018) |
Hesperetin | Nanocrystals of drug using phytantriol and lecithin with Pluronic F-127 or mannitol as surfactant | To improve site targeting using 2D and 3D arrays of nanocrystals | Shete et al. (2015) |
Paclitaxel | Eudragit-coated nanorods | For better therapeutic response by taking advantage of less macrophagial consumption of the polymer | Yilmaz et al. (2016) |
Platinum complex drugs | B-lactoglobulin-pectin encapsulated nanoparticles | To protect the drug through GIT using natural coating of pectin | Izadi et al. (2016) |