Research ArticleDrug Discovery and Translational Medicine
Exposure-Effect Relationships in Established Rat Adjuvant-Induced and Collagen-Induced Arthritis: A Translational Pharmacokinetic-Pharmacodynamic Analysis
Harvey Wong, Lichuan Liu, Wenjun Ouyang, Yuzhong Deng, Matthew R. Wright and Cornelis E.C.A. Hop
Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 406-418; DOI: https://doi.org/10.1124/jpet.118.255562
Harvey Wong
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
Lichuan Liu
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
Wenjun Ouyang
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
Yuzhong Deng
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
Matthew R. Wright
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
Cornelis E.C.A. Hop
Departments of Drug Metabolism and Pharmacokinetics (H.W., L.L., Y.D., M.R.W., C.E.C.A.H.) and Immunology (W.O.), Genentech Inc., South San Francisco, California
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Research ArticleDrug Discovery and Translational Medicine
Translational PK-PD Analysis of Rat Arthritis Models
Harvey Wong, Lichuan Liu, Wenjun Ouyang, Yuzhong Deng, Matthew R. Wright and Cornelis E.C.A. Hop
Journal of Pharmacology and Experimental Therapeutics June 1, 2019, 369 (3) 406-418; DOI: https://doi.org/10.1124/jpet.118.255562
Research ArticleDrug Discovery and Translational Medicine
Translational PK-PD Analysis of Rat Arthritis Models
Harvey Wong, Lichuan Liu, Wenjun Ouyang, Yuzhong Deng, Matthew R. Wright and Cornelis E.C.A. Hop
Journal of Pharmacology and Experimental Therapeutics June 1, 2019, 369 (3) 406-418; DOI: https://doi.org/10.1124/jpet.118.255562
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