A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques

Daicia C. Allen; Timothy L. Carlson; Yan Xiong; Jian Jin; Kathleen A. Grant; Verginia C. Cuzon Carlson

doi:10.1124/jpet.118.252031

Research ArticleNeuropharmacology

A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques

Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson

Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

Daicia C. Allen

Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon (D.C.A., K.A.G., V.C.C.C.); Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon (T.L.C., K.A.G., V.C.C.C.); and Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York (Y.X., J.J.)

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Timothy L. Carlson

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Yan Xiong

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Jian Jin

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Kathleen A. Grant

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Verginia C. Cuzon Carlson

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Journal of Pharmacology and Experimental Therapeutics

Vol. 368, Issue 2

1 Feb 2019

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Research ArticleNeuropharmacology