Index by author
May 01, 2018; Volume 365,Issue 2
A
Aburatani, Takahide
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Aguayo-Ortiz, Rodrigo
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Apland, James P.
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Aroniadou-Anderjaska, Vassiliki
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Atwal, Suman
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Azhar, Salman
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
B
Baksh, Shairaz
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Banoub, Mary G.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Bartko, Johann
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Baruffaldi, Federico
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Beeton, Christine
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Bhullar, Khushwant S.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Birnbaum, Angela K.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Bittner, Alex
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Bittner, Stefanie
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Blankstein, Anna R.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Boess, Franziska
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Bouchara, Jean-Philippe
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Braga, Maria F. M.
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Branch Woods, Amanda A.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Briet, Marie
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Brocks, Dion
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Brouwer, Kenneth R.
- You have accessFarnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and MechanismsCen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer and Kim L. R. BrouwerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 413-421; DOI: https://doi.org/10.1124/jpet.117.246033
Brouwer, Kim L. R.
- You have accessFarnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and MechanismsCen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer and Kim L. R. BrouwerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 413-421; DOI: https://doi.org/10.1124/jpet.117.246033
Burkey, Bryan F.
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
C
Cai, Wei
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Carroll, F. Ivy
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Chamberlain, Brayden H.
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Chan, Jackie K. W.
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Chang, Zhao
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Chen, Yan
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Cleator, John H.
- You have accessThe N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit DissociationJohn H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz and John D. HildebrandtJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 219-225; DOI: https://doi.org/10.1124/jpet.117.245779
Cobb, Denise A.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Cohen, Samuel M.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Conn, P. Jeffrey
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
D
Dagur, Raghubendra S.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Danmaliki, Gaddafi I.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Darios, Emma S.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Dingus, Jane
- You have accessThe N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit DissociationJohn H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz and John D. HildebrandtJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 219-225; DOI: https://doi.org/10.1124/jpet.117.245779
Diquet, Bertrand
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Dong, Kelly
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Droste, Miriam
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Durrwell, Alexandre
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
E
Edwards, Jeffrey E.
- You have accessFarnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and MechanismsCen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer and Kim L. R. BrouwerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 413-421; DOI: https://doi.org/10.1124/jpet.117.246033
Ekiciler, Aynur
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Elmquist, William F.
- You have accessPharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K. Laramy, Minjee Kim, Karen E. Parrish, Jann N. Sarkaria and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 249-261; DOI: https://doi.org/10.1124/jpet.117.246116
F
Fang, Yan
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Farquhar, Charlotte E.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Ferland, David J.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Figueiredo, Taiza H.
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Fisher, Nicole M.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Fiteh, Yahya
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Fong, Sunny
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Fowler, Stephen
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Fu, Tingting
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
G
Gamage, Thomas F.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Gao, Jie
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Gao, Na
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Garcia, Laura Ramos
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Gehrmann, Elizabeth J.
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Gendelman, Howard E.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Gibson, Spencer B.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Giglio, Daniel
- You have accessChanges in the Neuronal Control of the Urinary Bladder in a Model of Radiation CystitisDaniel Giglio, Lucie Podmolíková and Gunnar TobinJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 327-335; DOI: https://doi.org/10.1124/jpet.117.246371
Godon, Charlotte
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Gogliotti, Rocco G.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Gonsard, Pierre-Alexis
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Goosen, Theunis C.
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Goping, Ing Swie
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Gorantla, Santhi
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Gulko, Pércio S.
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Guo, Cen
- You have accessFarnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and MechanismsCen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer and Kim L. R. BrouwerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 413-421; DOI: https://doi.org/10.1124/jpet.117.246033
Gurumurthy, Channabasavaiah B.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
H
Hamadjida, Adjia
- You have accessPredictive Value of Parkinsonian Primates in Pharmacologic Studies: A Comparison between the Macaque, Marmoset, and Squirrel MonkeyNicolas Veyres, Adjia Hamadjida and Philippe HuotJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 379-397; DOI: https://doi.org/10.1124/jpet.117.247171
Harms, Donald W.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Hashimoto, Ryuji
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Hildebrandt, John D.
- You have accessThe N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit DissociationJohn H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz and John D. HildebrandtJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 219-225; DOI: https://doi.org/10.1124/jpet.117.245779
Hobl, Eva-Luise
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Hoglen, Niel C.
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
Huang, Liang
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Hubbard, Basil P.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Hughes, Thomas E.
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
Huot, Philippe
- You have accessPredictive Value of Parkinsonian Primates in Pharmacologic Studies: A Comparison between the Macaque, Marmoset, and Squirrel MonkeyNicolas Veyres, Adjia Hamadjida and Philippe HuotJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 379-397; DOI: https://doi.org/10.1124/jpet.117.247171
Huq, Redwan
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Hwang, Peter
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
I
Inayathullah, Mohammed
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Inskeep, Philip
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
Ishihara, Hidetoshi
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
J
Jilma, Bernd
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Jin, Han
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Jin, Yuyan
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Johnson, Nathaniel
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Jones, Carrie K.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Jones, Russell
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Joshi, Poonam S.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
K
Kalgutkar, Amit S.
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Kevin, Richard C.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Kim, Minjee
- You have accessPharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K. Laramy, Minjee Kim, Karen E. Parrish, Jann N. Sarkaria and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 249-261; DOI: https://doi.org/10.1124/jpet.117.246116
Klammers, Florian
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Kocher, Ted
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Kraemer, Fredric B.
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Kratochwil, Nicole A.
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Kretzschmar, Titus
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Kubica, Jacek
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Kurtz, David T.
- You have accessThe N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit DissociationJohn H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz and John D. HildebrandtJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 219-225; DOI: https://doi.org/10.1124/jpet.117.245779
L
LaCerte, Carl
- You have accessFarnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and MechanismsCen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer and Kim L. R. BrouwerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 413-421; DOI: https://doi.org/10.1124/jpet.117.246033
Laragione, Teresina
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Laramy, Janice K.
- You have accessPharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K. Laramy, Minjee Kim, Karen E. Parrish, Jann N. Sarkaria and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 249-261; DOI: https://doi.org/10.1124/jpet.117.246116
Laudenbach, Megan
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Lefever, Timothy W.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Legras, Pierre
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Lelièvre, Bénédicte
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Leonard, Brian
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Lin, Zhiwu
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Lin, Zhiyi
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Lindsley, Craig W.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Liu, Houfu
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Liu, Jihong
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Lu, Gang
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
M
Makarov, Edward
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Manaloor, Robin
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Marschmann, Michaela
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Marti, Andrea
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Marusich, Julie A.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Masuda, Yusuke
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Matschiner, Gabriele
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
McGregor, Iain S.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
McMillan, JoEllyn M.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Meier, Pascal
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Miyauchi, Ryuki
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Molitor, Birgit
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Moore, Jack
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Moscovitz, Jamie E.
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Mueller, Martina B.
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Mullick, Adam E.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
N
Nagano, Yuki
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Nagatomo, Kentaro
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Nara, Futoshi
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Nicolls, Mark R.
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Nishizawa, Tomohiro
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Niswender, Colleen M.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Nulick, Kelly
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
O
Okuno, Kazuaki
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Ottaviani, Giorgio
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
P
Pandya, Vrajeshkumar
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Parrish, Karen E.
- You have accessPharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K. Laramy, Minjee Kim, Karen E. Parrish, Jann N. Sarkaria and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 249-261; DOI: https://doi.org/10.1124/jpet.117.246116
Parrott, Neil J.
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Pennington, Michael W.
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Pentel, Paul R.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Peterson, Samantha J.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Phillips, Douglas J.
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Pidoplichko, Volodymyr I.
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Podmolíková, Lucie
- You have accessChanges in the Neuronal Control of the Urinary Bladder in a Model of Radiation CystitisDaniel Giglio, Lucie Podmolíková and Gunnar TobinJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 327-335; DOI: https://doi.org/10.1124/jpet.117.246371
Poluektova, Larisa Y.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Pravetoni, Marco
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Q
Qiao, Hai-Ling
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Quadros, Rolen M.
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
R
Rajada, Jayakumar
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Raleigh, Michael D.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Riou, Jérémie
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Roslawski, Michaela J.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
Rossetti, Katia
- You have accessComparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric PopulationJames P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Volodymyr I. Pidoplichko, Katia Rossetti and Maria F. M. BragaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 314-326; DOI: https://doi.org/10.1124/jpet.117.245969
Runyon, Scott P.
- You have accessOpioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in RatsMichael D. Raleigh, Megan Laudenbach, Federico Baruffaldi, Samantha J. Peterson, Michaela J. Roslawski, Angela K. Birnbaum, F. Ivy Carroll, Scott P. Runyon, Scott Winston, Paul R. Pentel and Marco PravetoniJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 346-353; DOI: https://doi.org/10.1124/jpet.117.247049
S
Said, Ahmed
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Salla, Mohamed
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Sarkaria, Jann N.
- You have accessPharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K. Laramy, Minjee Kim, Karen E. Parrish, Jann N. Sarkaria and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 249-261; DOI: https://doi.org/10.1124/jpet.117.246116
Schmaler, Josephine
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Schoergenhofer, Christian
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Schwameis, Michael
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Seitz, Bridget
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Shamshiev, Abdijapar
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Shen, Wen-Jun
- You have accessNordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in MiceJackie K. W. Chan, Stefanie Bittner, Alex Bittner, Suman Atwal, Wen-Jun Shen, Mohammed Inayathullah, Jayakumar Rajada, Mark R. Nicolls, Fredric B. Kraemer and Salman AzharJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 281-290; DOI: https://doi.org/10.1124/jpet.117.243733
Stansley, Branden J.
- You have accessTotal RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G. Gogliotti, Nicole M. Fisher, Branden J. Stansley, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn and Colleen M. NiswenderJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 291-300; DOI: https://doi.org/10.1124/jpet.117.246991
Summerfield, Scott G.
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Sun, Xueying
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Suzuki, Chikako
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Suzuki, Eiko
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Szabó, Emese
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
T
Takahashi, Tohru
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Tanner, Mark R.
- You have accessTargeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid ArthritisMark R. Tanner, Michael W. Pennington, Brayden H. Chamberlain, Redwan Huq, Elizabeth J. Gehrmann, Teresina Laragione, Pércio S. Gulko and Christine BeetonJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 227-236; DOI: https://doi.org/10.1124/jpet.117.245118
Terstappen, Georg C.
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Thomas, Brian F.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Thompson, Janice M.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Tobin, Gunnar
- You have accessChanges in the Neuronal Control of the Urinary Bladder in a Model of Radiation CystitisDaniel Giglio, Lucie Podmolíková and Gunnar TobinJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 327-335; DOI: https://doi.org/10.1124/jpet.117.246371
Tournillac, Charles A.
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Triyatni, Miriam
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Turley, Dan
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
U
Ullah, Mohammed
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
V
Vandeputte, Patrick
- You have accessImpact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral ScedosporiosisBénédicte Lelièvre, Marie Briet, Charlotte Godon, Pierre Legras, Jérémie Riou, Patrick Vandeputte, Bertrand Diquet and Jean-Philippe BoucharaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 408-412; DOI: https://doi.org/10.1124/jpet.117.245449
Vath, James E.
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
Velázquez-Martínez, Carlos A.
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Veyres, Nicolas
- You have accessPredictive Value of Parkinsonian Primates in Pharmacologic Studies: A Comparison between the Macaque, Marmoset, and Squirrel MonkeyNicolas Veyres, Adjia Hamadjida and Philippe HuotJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 379-397; DOI: https://doi.org/10.1124/jpet.117.247171
Vliagoftis, Harissios
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
W
Wadowski, Patricia
- Open AccessMorphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy VolunteersJohann Bartko, Christian Schoergenhofer, Michael Schwameis, Patricia Wadowski, Jacek Kubica, Bernd Jilma and Eva-Luise HoblJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 430-436; DOI: https://doi.org/10.1124/jpet.117.247213
Walter, Isabelle
- Open AccessSimultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus InhibitorNicole A. Kratochwil, Miriam Triyatni, Martina B. Mueller, Florian Klammers, Brian Leonard, Dan Turley, Josephine Schmaler, Aynur Ekiciler, Birgit Molitor, Isabelle Walter, Pierre-Alexis Gonsard, Charles A. Tournillac, Alexandre Durrwell, Michaela Marschmann, Russell Jones, Mohammed Ullah, Franziska Boess, Giorgio Ottaviani, Yuyan Jin, Neil J. Parrott and Stephen FowlerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 237-248; DOI: https://doi.org/10.1124/jpet.117.245712
Wan, Zehong
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Wang, Cai-E.
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Wang, Gao-Ju
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Wang, Jianfei
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Wang, Jie
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Wang, Weimin
- Open AccessAntiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG MiceJoEllyn M. McMillan, Denise A. Cobb, Zhiyi Lin, Mary G. Banoub, Raghubendra S. Dagur, Amanda A. Branch Woods, Weimin Wang, Edward Makarov, Ted Kocher, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Samuel M. Cohen, Howard E. Gendelman, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. PoluektovaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 272-280; DOI: https://doi.org/10.1124/jpet.117.247288
Wang, Zhao
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Watts, Stephanie W.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Weller, Michael
- You have accessAntitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma ModelsEmese Szabó, Douglas J. Phillips, Miriam Droste, Andrea Marti, Titus Kretzschmar, Abdijapar Shamshiev and Michael WellerJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 422-429; DOI: https://doi.org/10.1124/jpet.117.246249
Wells, Christopher A.
- You have accessThe N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit DissociationJohn H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz and John D. HildebrandtJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 219-225; DOI: https://doi.org/10.1124/jpet.117.245779
Weng, Yan
- You have accessEstablishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human HepatocytesJamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen and Yan WengJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 262-271; DOI: https://doi.org/10.1124/jpet.117.247296
Wiley, Jenny L.
- You have accessMolecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICAThomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley and Brian F. ThomasJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 437-446; DOI: https://doi.org/10.1124/jpet.117.246983
Winston, Scott
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Wu, Shengqian
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Wyman, Margaret
- You have accessPreclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061Bryan F. Burkey, Niel C. Hoglen, Philip Inskeep, Margaret Wyman, Thomas E. Hughes and James E. VathJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 301-313; DOI: https://doi.org/10.1124/jpet.117.246272
Y
Yamaguchi, Shinji
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Yamamura, Naotoshi
- You have accessGeneration and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain–Fused Anticalin ProteinYusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi and Tomohiro NishizawaJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 368-378; DOI: https://doi.org/10.1124/jpet.117.246652
Yang, Ting
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Yeh, Steve T.
- You have accessWhole-Body but Not Hepatic Knockdown of Chemerin by Antisense Oligonucleotide Decreases Blood Pressure in RatsDavid J. Ferland, Bridget Seitz, Emma S. Darios, Janice M. Thompson, Steve T. Yeh, Adam E. Mullick and Stephanie W. WattsJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 212-218; DOI: https://doi.org/10.1124/jpet.117.245456
Yu, Xiaohong
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Z
Zare, Alaa
- Open AccessIdentification and Characterization of Novel Receptor-Interacting Serine/Threonine‐Protein Kinase 2 Inhibitors Using Structural Similarity AnalysisMohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I. Danmaliki, Alaa Zare, Ahmed Said, Jack Moore, Vrajeshkumar Pandya, Robin Manaloor, Sunny Fong, Anna R. Blankstein, Spencer B. Gibson, Laura Ramos Garcia, Pascal Meier, Khushwant S. Bhullar, Basil P. Hubbard, Yahya Fiteh, Harissios Vliagoftis, Ing Swie Goping, Dion Brocks, Peter Hwang, Carlos A. Velázquez-Martínez and Shairaz BakshJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 354-367; DOI: https://doi.org/10.1124/jpet.117.247163
Zhang, Hong-Xin
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Zhang, Wandong
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Zhang, Yun-Fei
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Zhen, Wei
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
Zhou, Jun
- You have accessHigher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by DiethylnitrosamineJie Gao, Zhao Wang, Gao-Ju Wang, Hong-Xin Zhang, Na Gao, Jie Wang, Cai-E. Wang, Zhao Chang, Yan Fang, Yun-Fei Zhang, Jun Zhou, Han Jin and Hai-Ling QiaoJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 398-407; DOI: https://doi.org/10.1124/jpet.117.245555
Zhu, Xiaoyan
- You have accessDrug Distribution into Peripheral NerveHoufu Liu, Yan Chen, Liang Huang, Xueying Sun, Tingting Fu, Shengqian Wu, Xiaoyan Zhu, Wei Zhen, Jihong Liu, Gang Lu, Wei Cai, Ting Yang, Wandong Zhang, Xiaohong Yu, Zehong Wan, Jianfei Wang, Scott G. Summerfield, Kelly Dong and Georg C. TerstappenJournal of Pharmacology and Experimental Therapeutics May 2018, 365 (2) 336-345; DOI: https://doi.org/10.1124/jpet.117.245613
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