Research ArticleCardiovascular
Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide–Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model
Helen Christou, Hannes Hudalla, Zoe Michael, Evgenia J. Filatava, Jun Li, Minglin Zhu, Jose S. Possomato-Vieira, Carlos Dias-Junior, Stella Kourembanas and Raouf A. Khalil
Journal of Pharmacology and Experimental Therapeutics February 2018, 364 (2) 258-274; DOI: https://doi.org/10.1124/jpet.117.244798
Helen Christou
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Hannes Hudalla
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Zoe Michael
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Evgenia J. Filatava
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Jun Li
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Minglin Zhu
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Jose S. Possomato-Vieira
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Carlos Dias-Junior
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Stella Kourembanas
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
Raouf A. Khalil
Department of Pediatric Newborn Medicine (H.C., H.H., Z.M., E.J.F., S.K.), and Division of Vascular and Endovascular Surgery (J.L., M.Z., J.S.P.-V., C.D.-J., R.A.K.), Brigham and Women’s Hospital, and Division of Newborn Medicine, Children’s Hospital (H.C., S.K.), Harvard Medical School, Boston, Massachusetts; and Department of Neonatology, Children’s University Hospital, Heidelberg, Germany (H.H.)
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In this issue
Research ArticleCardiovascular
Pulmonary Vascular Dysfunction in Pulmonary Hypertension
Helen Christou, Hannes Hudalla, Zoe Michael, Evgenia J. Filatava, Jun Li, Minglin Zhu, Jose S. Possomato-Vieira, Carlos Dias-Junior, Stella Kourembanas and Raouf A. Khalil
Journal of Pharmacology and Experimental Therapeutics February 1, 2018, 364 (2) 258-274; DOI: https://doi.org/10.1124/jpet.117.244798
Research ArticleCardiovascular
Pulmonary Vascular Dysfunction in Pulmonary Hypertension
Helen Christou, Hannes Hudalla, Zoe Michael, Evgenia J. Filatava, Jun Li, Minglin Zhu, Jose S. Possomato-Vieira, Carlos Dias-Junior, Stella Kourembanas and Raouf A. Khalil
Journal of Pharmacology and Experimental Therapeutics February 1, 2018, 364 (2) 258-274; DOI: https://doi.org/10.1124/jpet.117.244798
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