Research ArticleDrug Discovery and Translational Medicine
Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy
Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283
Mark R. Kelley
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
James H. Wikel
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Chunlu Guo
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Karen E. Pollok
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Barbara J. Bailey
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Randy Wireman
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Melissa L. Fishel
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
Michael R. Vasko
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
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In this issue
Research ArticleDrug Discovery and Translational Medicine
Targeting APE1 for Prevention of CIPN
Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 1, 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283
Research ArticleDrug Discovery and Translational Medicine
Targeting APE1 for Prevention of CIPN
Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 1, 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283
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