Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
Blocking Sirtuin 1 and 2 Inhibits Renal Interstitial Fibroblast Activation and Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy
Murugavel Ponnusamy, Xiaoxu Zhou, Yanli Yan, Jinhua Tang, Evelyn Tolbert, Ting C. Zhao, Rujun Gong and Shougang Zhuang
Journal of Pharmacology and Experimental Therapeutics August 2014, 350 (2) 243-256; DOI: https://doi.org/10.1124/jpet.113.212076
Murugavel Ponnusamy
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Xiaoxu Zhou
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Yanli Yan
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Jinhua Tang
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Evelyn Tolbert
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Ting C. Zhao
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Rujun Gong
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
Shougang Zhuang
Department of Medicine, Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island (M.P., X.Z., Y.Y., E.T., R.G., S.Z.); First Affiliated Hospital of Harbin Medical University, Harbin, China (X.Z.); Departments of Nephrology (J.T., S.Z.) and Emergency Medicine (Y.Y.), Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; and Department of Surgery, Roger William Medical Center, Boston University Medical School, Providence, Rhode Island (T.C.Z.)
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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
SIRT1/2 Mediates Renal Fibrosis
Murugavel Ponnusamy, Xiaoxu Zhou, Yanli Yan, Jinhua Tang, Evelyn Tolbert, Ting C. Zhao, Rujun Gong and Shougang Zhuang
Journal of Pharmacology and Experimental Therapeutics August 1, 2014, 350 (2) 243-256; DOI: https://doi.org/10.1124/jpet.113.212076
Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal
SIRT1/2 Mediates Renal Fibrosis
Murugavel Ponnusamy, Xiaoxu Zhou, Yanli Yan, Jinhua Tang, Evelyn Tolbert, Ting C. Zhao, Rujun Gong and Shougang Zhuang
Journal of Pharmacology and Experimental Therapeutics August 1, 2014, 350 (2) 243-256; DOI: https://doi.org/10.1124/jpet.113.212076
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